Clinical trials: IBD-Inflammatory Bowel Disease
Colitis, Ulcerative
Trichuris Suis Ova Treatment in Left-sided Ulcerative Colitis
The purpose of this study is to evaluate the safety and effectiveness of trichuris suis ova (TSO) in ulcerative colitis (UC). We will look at how TSO affects the body's immune response and if there are related changes in…
- Trial name
- NCT01953354
- Testing
- Trichuris suis ova (TSO)
- Where
- 17 sites in United States
- Volunteers
- 16 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ulcerative Colitis
Golimumab in Ulcerative Colitis (UC) Patients With Loss of Response (LOR) Followed by Dose Optimization
It is planned to enroll 80 UC patients who will require optimization of golimumab after secondary LOR. The review of the study protocol and its approval by an Independent Ethics Committee of the University of Saint Etienne are…
- Trial name
- GOLILOR (NCT03182166)
- Testing
- Golimumab (Optimization), Rectosigmoidoscopy, Blood samples
- Where
- 5 sites in France
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Ulcerative Colitis, Crohn's Disease
VEST: The UK Vedolizumab Real Life Experience Study in Inflammatory Bowel Disease
Vedolizumab has been approved for the treatment of both ulcerative colitis and Crohn's disease. The aim of this study is to capture the early real life UK experience of vedolizumab including the outcomes of treatment, describing…
- Trial name
- VEST (NCT03257345)
- Where
- 22 sites in United Kingdom
- Volunteers
- 360 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Malnutrition, Cancer
Impact of a New Plant-based High-energy Oral Nutritional Supplement on Nutritional Outcomes in Malnourished Patients
This study aims to compare nutritional outcomes in terms of percentage of weight gain between a new planted-based high-energy ONS and a standard high-energy ONS with animal protein (cow's mil protein) in patients at malnutrition…
- Conditions
- Malnutrition, Cancer, Inflammatory Bowel Diseases, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT06055543
- Testing
- Fortimel
- Where
- 6 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Danone Specialized Nutrition
Ulcerative Colitis (UC)
A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)
This study is designed to evaluate the long-term safety and efficacy of Upadacitinib in participants with ulcerative colitis (UC) who have not responded at the end of the induction period in Study M14-234 Substudy 1, who have had…
- Trial name
- U-ACTIVATE (NCT03006068)
- Testing
- Upadacitinib (ABT-494)
- Where
- 492 sites in United States, Argentina and 44 more
- Volunteers
- 950 people
- Sponsor
- AbbVie
Crohn Disease (CD), Ulcerative Colitis (UC)
IBD Biomarker Discovery and Validation Platform
The goal of this observational study is to establish a multicenter prospective clinical and biospecimen platform for biomarker discovery and validation in inflammatory bowel disease, including Crohn's disease and ulcerative…
- Conditions
- Crohn Disease (CD), Ulcerative Colitis (UC), Inflammatory Bowel Diseases (IBD)
- Trial name
- IBD-BIOP (NCT07686406)
- Where
- 2 sites in China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Crohn Disease, Ulcerative Colitis
Changes in Faecal Calprotectin Levels and Participation-related Scores Following Three Weeks of Inpatient Rehabilitation
For many people affected by inflammatory bowel disease (IBD), their quality of life and their ability to participate in their professional and social lives are severely restricted.
- Trial name
- NCT05500040
- Testing
- Multimodal Rehabilitation
- Where
- Austria
- Volunteers
- 226 people
- Sponsor
- Pensionsversicherungsanstalt
Ulcerative Colitis
T Lymphocyte Subsets in Ulcerative Colitis
1. Study the distribution of peripheral blood T lymphocyte subsets among ulcerative colitis patients. 2. Correlation of T-cell subsets to therapeutic response/ disease activity. 3.
- Trial name
- NCT06352515
- Testing
- Flow cytometry
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Thyroid Disease, Irritable Bowel Disease
Study of Thyroid Status in Patients With IBD
. The aim of the present study is to study thyroid state in patients with IBD
- Trial name
- NCT05542368
- Testing
- Thyroid tests
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ulcerative Colitis
Human Umbilical-Cord-Derived Mesenchymal Stem Cell Therapy in Active Ulcerative Colitis
Phase I-II Clinical Trial - Safety and efficacy of umbilical-cord-derived mesenchymal stem cell (UC-MSC) in patients with active ulcerative colitis，randomized, single blind, controlled prospective study.
- Trial name
- UCMSC-UC (NCT02442037)
- Testing
- UCMSC group, Control group(Normal saline)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Crohn Disease (CD), Cryptoglandular Perianal Fistula
A Study Comparing Transperineal Ultrasound, Magnetic Resonance Imaging, Endoscopic Ultrasound, and Examination Under Anesthesia to Detect and Classify Perianal Fistulas in Patients With Crohn's Disease or Fistulas of Unknown Cause
The goal of this study is to learn how well different imaging tests detect and describe perianal fistulas in adults with Crohn's disease or fistulas with no known cause (cryptogenic).
- Trial name
- TRANSIT CD (NCT07794410)
- Testing
- Transperineal Ultrasound (TPUS), Magnetic Resonance Imaging (MRI), Endoscopic Ultrasound (EUS)
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Asian Institute of Gastroenterology, India
Crohn's Disease
TOward a Better Understanding of the autoPhagy Machinery for the Identification of Potential Novel Biomarkers and Therapeutic Targets in Crohn's Disease - TOPIC Study
Crohn's disease (CD) belongs to chronic inflammatory bowel diseases (IBD) affecting over 2 million individuals in the North America and 3.2 million in Europe with an increasing incidence rate in newly industrialized countries…
- Trial name
- TOPIC (NCT06244849)
- Testing
- Blood samples, Stool simple, Ileocolonic biopsies
- Where
- 2 sites in France
- Volunteers
- 170 people
- Sponsor
- Hospices Civils de Lyon
Inflammatory Bowel Diseases, Crohn Disease
Utility of Random Biopsies in Patients With Inflammatory Bowel Disease
The proposed study is a multicenter parallel group clinical trial that will include 821 evaluable patients per group who will be randomly assigned to either high definition white light colonoscopy (HDWLC) with targeted biopsies…
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- URBI (NCT06560021)
- Testing
- Biopsy strategy
- Where
- 21 sites in United States
- Volunteers
- 1,642 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Crohn's Disease
Urinary Prostaglandin E Metabolite (PGE-M), A Metabolite of Prostaglandin E2 (PGE2): A Novel Biomarker of Crohn's Disease Activity
The purpose of this study is to determine whether urinary PGE-M levels correlate with Crohn's disease activity and to compare how well urinary PGE-M correlates with other non-invasive biomarkers of disease activity such as…
- Trial name
- NCT00496548
- Testing
- Fecal calprotectin, Urinary PGE-M Level
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Vanderbilt University Medical Center
Patient With an Indication of Colonoscopy for Inflammatory Bowel Disease
National Multicentric Observatory of Low Bowel Preparations in Patients With IBD
National multicentric observatory of low bowel preparations in patients with IBD
- Trial name
- CLEAN (NCT03753425)
- Testing
- Low volume bowel preparation in inflammatory bowel diseases
- Where
- France
- Volunteers
- 278 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Inflammatory Bowel Diseases, Crohn Disease
Effects of an Intermittent Reduced Calorie Diet on Crohn's Disease
The purpose of this study is to see how an Intermittent Calorie Reduced Diet (IRCD) that mimics fasting (also known as a fasting mimicking diet, FMD) effects inflammation in patients with mild to moderate Crohn's disease (CD).
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Diet Modification
- Trial name
- NCT04147585
- Testing
- Intermittent Reduced Calorie Diet (IRCD)
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Stanford University
Crohn's Disease
One Year Study of Rifaximin Delayed Release (DR) in Crohn's Disease
The primary objective is to determine the efficacy of rifaximin DR also referred to as Extended Intestinal Release (EIR) tablets vs.
- Trial name
- NCT02240108
- Testing
- Rifaximin EIR
- Where
- 78 sites in United States
- Volunteers
- 81 people
- Sponsor
- Bausch Health Americas, Inc.
Crohn Disease
Surgically Resected Crohn's Disease Patients: Prognostic Factors for Re-operation and New Score Building
The project will consist of a multicentre, prospective, observational study with a total duration of 24 months. Clinical, endoscopic and ultrasound data will be collected in a dedicated database (on IG-IBD Register), which will…
- Trial name
- POCD2017 (NCT03150238)
- Testing
- observation of prognostic factors for relapse
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Istituto Clinico Humanitas
Crohn Disease
Surgery vs Biologics for Treating Stricturing CD--a RCT
The management of stricturing Crohn's disease (CD) remains challenging. Although surgical resection may be the final way to solve it, the efficacy of biologics for symptomatic CD associated strictures was acceptable.
- Trial name
- NCT05421455
- Testing
- Group A, Group B
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Zhu Weiming
Crohn's Disease
Infliximab, Regulatory T Cells, IL2 and Crohn's Disease
Crohn's disease is an inflammatory (swelling and soreness) disorder of the digestive tract. Affected patients suffer from abdominal pains, diarrhea (sometimes bloody), weight loss.
- Trial name
- NCT01266785
- Testing
- Infliximab
- Where
- United States
- Sponsor
- Oregon Health and Science University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.