Clinical trials: ICU Patients
Intensive Care Unit Patients
Effects of Exercise Intervention on Muscle Strength in Severely Ill Patients
In recent years, due to the improvement in the survival rate of the intensive care unit, the problem of severe systemic fatigue (Intensive care unit acquired weakness; ICUAW) has continued to receive attention.
- Trial name
- NCT05342129
- Testing
- exercise bike
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Severe Pneumonia
The Application of Different Sedation Protocols in ICU Patients With Severe Pneumonia
This study collected data from patients with severe pneumonia to compare the duration of mechanical ventilation under different sedation regimens in real-world settings.
- Trial name
- ICU (NCT06514781)
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Xiangya Hospital of Central South University
Critical Illness, Muscle Weakness
Can Beta-Hydroxy-beta-Methylbutyrate Supplementation Counteract Muscle Catabolism in Critically Ill Patients?
The rapid decline of muscle mass and function in mechanically ventilated critically ill patients is associated with prolonged length of mechanical ventilation, prolonged intensive care (ICU) and hospital stay, increased ICU and…
- Trial name
- HMB-ICU-CH (NCT03628365)
- Testing
- HMB (beta-hydroxy beta-methylbutyrate)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Mette M Berger
Weaning Mechanical Ventilation, Ultrasonography
The Relationship Between Diaphragm Function Assessed by Ultrasound and Weaning Success in Mechanically Ventilated Patients in the ICU
The diaphragm is the most important muscle involved in the respiratory system and is solely responsible for approximately 65-80% of vital capacity.
- Conditions
- Weaning Mechanical Ventilation, Ultrasonography, Intensive Care (ICU), Assesment of Diaphragmatic Function by Ultrasound to Predict Weaning Success in Mechanical Ventilated Intensive Care Unit Patients
- Trial name
- ICU (NCT07332403)
- Testing
- Diaphragm ultrasound before weaning procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Ventilator Associated Pneumonia
Antibiotic Prophylaxis for Early Ventilator-associated Pneumonia in Neurological Patients
This study seeks to assess whether coma patients really benefit from the use of antibiotics as a prophylactic for reducing the incidence of early ventilator-associated pneumonia in this population group.
- Trial name
- NAVPRO (NCT01118403)
- Testing
- Sultamicillin
- Where
- Colombia
- Sponsor
- Hospital Pablo Tobón Uribe
Ventilation Therapy; Complications
Diaphragmatic Mobility In Ventilated Assisted Patients
The study was a randomized controlled trial. A total of 24 patients who met the inclusion criteria were included in this study and randomly divided by sealed envelope method into Experimental and Control groups with 12 patients…
- Trial name
- NCT04733261
- Testing
- Diaphragmatic mobility, Chest Physiotherapy
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aqua Medical Services (Pvt) Ltd
Hyperglycemia
Humalog or Humulin for Intensive Insulin Therapy in Intensive Care Unit
Insulin preparation -random assignment to regular insulin lin or lispro insulin as first treatment- was administered at constant infusion rate (0.04 units/Kg/h) in patients presenting blood glucose concentration ≥180 mg/dl and…
- Trial name
- NCT02165566
- Testing
- Regular-insulin, Lispro-insulin
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- University of Roma La Sapienza
Acute Respiratory Distress Syndrome
Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study)
Numerous trials support the efficacy and safety of volatile anesthetic agents, namely inhalation of sevoflurane through dedicated devices, for the sedation of ICU patients.
- Trial name
- SEGA (NCT02166853)
- Testing
- sevoflurane, midazolam
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Frailty Syndrome
Adaptation and Validation of Frailty Scales in Intensive Care Units in Spain
Increased life expectancy leads to population aging, increased morbidities and aging of hospitalized patients. The acquisition of frailty leads to worse outcomes derived from hospitalization, but although frailty has been related…
- Trial name
- NCT04830865
- Where
- Spain
- Volunteers
- 512 people
- Sponsor
- Hospital Universitario Getafe
Patient Safety
Machine Learning Prediction of Parameters of Early Warning Scores in Intensive Care Units
A large number of different organ functions are recorded in real time for patients being monitored in an intensive care unit. On the one hand, the measured values collected are used for continuous monitoring of vital parameters…
- Trial name
- AIM-PEW-ICU (NCT06259812)
- Testing
- Parameters of Early Warning Scores
- Where
- Austria
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Kepler University Hospital
Post Intensive Care Syndrome, Intensive Care Unit Acquired Weakness
Validity and Reliability of Korean Version of AM-PAC Inpatient Short Form (Low Function) in Critically Ill Patients
The Activity Measure for Post Acute Care (AM-PAC) inpatient short form (low function) evaluates the level of assistance a patient requires another person to provide for distinct functional mobility and daily activities.
- Trial name
- AM-PAC (NCT06440265)
- Testing
- AM-PAC inpatient short form (low function)
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Seoul National University Hospital
Myasthenia Gravis, Guillain-Barre Syndrome
Ventilator Weaning Practices in Patients Intubated for Guillain-Barré Syndrome or Myasthenia Gravis
Guillain-Barré syndrome and myasthenia gravis are two neuromuscular diseases that are commonly managed in ICUs that may require different weaning protocols.
- Trial name
- GUIMAUVE (NCT07022028)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Poitiers University Hospital
Critical Illness, Elevated Left Atrial Pressure
The Use of Single-Beat TE-e' in Evaluation of Left Atrial Pressure in Critically Ill Patients: The TELAP-ICU Trial
This study evaluates a new single-beat echocardiographic technique (TE-e', the time difference between the onset of the mitral inflow E wave and the septal e' wave on tissue Doppler imaging) for estimating left atrial pressure…
- Conditions
- Critical Illness, Elevated Left Atrial Pressure, Left Ventricular Diastolic Dysfunction, Echocardiography
- Trial name
- TELAP-ICU (NCT07820319)
- Testing
- Echocardiography
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Thorax Traumas
The Investigation of Predicting Mortality and Morbidity in Patients Admitted to Intensive Care Unit With Thoracic Trauma Using Selected Biomarkers and Parameters
This prospective study aimed to predict morbidity and mortality after thoracic trauma in intensive care unit evaluated clinical and biochemical data of 50 intensive care unit patients.
- Trial name
- NCT06930222
- Testing
- blood sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Suleyman Demirel University
Cardiac Disease
Dysphagia and VFMI in Cardiac Patients
The proposed study seeks to determine the incidence of dysphagia and vocal fold mobility impairment (VFMI) in individuals undergoing cardiothoracic surgical procedures.
- Trial name
- NCT03768739
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing
- Where
- 3 sites in United States
- Volunteers
- 207 people
- Sponsor
- University of Florida
Delirium, Validity
Validation of the 3D-CAM Turkish Version
3D CAM into Turkish validity and reliability on postoperative delirium will be test as a prospective diagnostic study. After approval by Dr. Edward R. Marcantonio, (15) will translation and back-translation.
- Trial name
- NCT04853706
- Testing
- 3d cam, DSM 5
- Volunteers
- 245 people
- Sponsor
- Aydin Adnan Menderes University
Airway Extubation
Maximum Expiratory Pressure in Induced Cough as a Predictor of Extubation Failure
Clinical trial for the evaluation of diagnostic tests. The sample was composed of adults under mechanical ventilation who passed the spontaneous breathing trial and was ready to be extubated.
- Trial name
- NCT04356625
- Testing
- MEPic
- Where
- Argentina
- Volunteers
- 80 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
Mechanical Ventilator Weaning, Acute Brain Injury
Brain-injured Patients Extubation Readiness Study
The BIPER study is a stepped wedge cluster randomised clinical trial aiming to decrease extubation failure in critically-ill brain-injured patients with residual impaired consciousness using a simple clinical score.
- Conditions
- Mechanical Ventilator Weaning, Acute Brain Injury, Altered Level of Consciousness, Mechanical Ventilation
- Trial name
- Biper (NCT04080440)
- Testing
- Extubation readiness clinical score, Usual Care
- Where
- 21 sites in France
- Volunteers
- 660 people
- Sponsor
- University Hospital, Clermont-Ferrand
Microcirculation
Comparison Between Dexmedetomidine and Propofol for Patients in the Intensive Care Unit After Abdominal Surgery
This is a single-blind randomized clinical trial. Patients undergoing abdominal surgery will be enrolled and randomly divided into two groups: dexmedetomidine group and propofol group.
- Trial name
- NCT02874768
- Testing
- Dexmedetomidine, Propofol
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Sepsis, Shock
The Effect of Erythropietin on Microcircualtory Alteration in Intensive Care Unit Patients With Severe Sepsis
The objective of this study is to determine if observations the investigators made in an animal model of sepsis can be translated to clinical practice.
- Trial name
- NCT01087450
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- London Health Sciences Centre