Clinical trials: IMPLANTATION
Infertility, Recurrent Pregnancy Loss
TNFα and MFG-E8: Novel Biomarkers to Predict Implantation Failure
Question: Can implantation failure (IF) be predicted prior to in vitro fertilization (IVF)? A pilot, non-interventional, clinical study Prospective, controlled, cohort study
- Trial name
- NCT02386384
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Maxilla, Tooth Loss / Rehabilitation
Loading Protocols for Dental Implants Placed in Healed Fully Edentulous Maxilla
The goal of this clinical trial is to compare immediate versus early loading protocols for complete implant-supported fixed dental prostheses in healed edentulous maxillae.
- Trial name
- NCT07574099
- Testing
- Immediate implant loading, Early loading
- Where
- Serbia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Edentulous Alveolar Ridge
Effectiveness of Removable Prosthesis Retained by 4 Implant-supported Locator-Attachments
1. Hypothesis/Specific aims The aim of the present study proposal is to validate an implant treatment concept in the edentulous upper maxilla using four implants-supported locators abutments to retain removable prosthesis.
- Trial name
- LOC (NCT02380404)
- Testing
- Implants-supported locators placement
- Where
- 2 sites in Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Liege
Implant
A 1-year Clinical Investigation on the On1 Concept
A 1-year Clinical Investigation on the On1 Concept.
- Trial name
- T-190 (NCT03100448)
- Testing
- On1 Concept
- Where
- 6 sites in Belgium, Italy and 2 more
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Implant, Zinc Status
Zinc Incorporated Bovine Derived- Hydroxyappatite Xenograft in Immediately Placed Implant
The aim of this study is to evaluate Clinical and radiographic effect of zinc incorporated bovine derived hydroxyapatite xenograft and bovine hydroxyapatite xenograft alone for immediately placed implant
- Trial name
- NCT07187609
- Testing
- Immediate implant with bovine drived hydroxyapatite xenograft., immediate implant with zinc incorporated bovine drived hydroxyapatite xenograft
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Complete Edentulism
Clinical Performance and Stability of Different Types of Implant Supported Overdenture
A Total number of 36 implants were installed in 6 patients having mandibular single denture. The patients were divided into two groups according to the definitive prosthesis.
- Trial name
- NCT05972538
- Testing
- Osstell ( Osstell AB, Goteborg, Sweden)., periodontal probe (Vivacare, TPS, Vivadent, Schaan, Lichtenstein, questionnaire for patient satisfaction
- Where
- Egypt
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Head and Neck Cancer, Oral Cancer
Improved Implant for Reconstruction Purposes After Mandibular Resection
Study design: A single center non-randomized, prospective clinical feasibility study. Study population: Study population is composed of 10 patients ineligible for a free-flap bone reconstruction.
- Trial name
- RifRam (NCT05153733)
- Testing
- RIFRAM implant
- Where
- Netherlands
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The Netherlands Cancer Institute
Healthy Subjects
Peri-Implant Soft Tissue Integration in Humans: Influence of Material
The purpose of this study is to compare the mucointegration of 2 types of surface roughness of zirconia abutments with titanium. The surface roughness will be machined and ultra-polished.
- Trial name
- NCT05805033
- Testing
- Mucointegration
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Sinus; Dental, Implant Complication
Evaluation of the Efficacy of Allograft Versus Tenting Technique in Open Sinus Lifting With Immediate Implant Placement
Implant placement in deficient posterior maxilla is a challenging clinical situation that necessitates appropriate treatment options to restore this area.
- Conditions
- Sinus; Dental, Implant Complication, Surgery-Complications
- Trial name
- NCT06254378
- Testing
- Sinus lifting with allograft, Sinus lifting without graft
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Resorption
Bone Changes Assessment in Screw-Retained Maxillary Complete Denture With Electric Welded Framework Versus Cast One
comparing bony changes around implants that will be joined by ametal framework either with electric weiling or with the conventional casting metal
- Trial name
- NCT04548258
- Testing
- electric intraoral weilding, casting
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Loss, Edentulousness
Soft Tissue Thickness on Submerged and Non Submerged Implants
Changes in the marginal bone level surrounding the implant are the frequently used parameters in assessing the short- and long-term success.
- Trial name
- NCT02842385
- Testing
- Implant
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ege University
Maxillary Sinus Floor Augmentation
Evaluation of Crestal Sinus Floor Elevation Using Densah Burs Via Surgical Guide and Simultaneous Implant Placement
Ten patients with missing maxillary posterior teeth and maxillary sinus pneumatization in this study .the floor of maxillary sinus will be elevated using densah drill via surgical guide with simultaneous implant placement .
- Trial name
- NCT06902454
- Testing
- densah drill technique
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tanta University
Tooth Loss
The Effect of Pre-operative Single Dose Antibiotic Prophylaxis on the Post-operative Implant Success
There is no consensus on antibiotic prophylaxis in dental implant applications, and its necessity is controversial. Current reports on antibiotic use are insufficient.
- Trial name
- NCT04856319
- Testing
- Dental implant placement, Antibiotic prophylaxis
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Biruni University
Contraception
Ethyl Chloride Spray Versus Subcutaneous Lidocaine Anaesthetic Prior to Contraceptive Implant Insertion
Study to look at the acceptability of local anaesthetic spray versus injection, prior to contraceptive implant insertion
- Trial name
- NCT02651207
- Testing
- Questionnaire based study looking at pain scores felt by patients either having a lidocaine injection or ethyl chloride spray prior to insertion of a contraceptive implant
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tayside Medical Science Centre
Alveolar Ridge Augmentation, Bone Transplantation
Peri-Implant Soft and Hard Tissue Stability Following Socket Preservation
The viability of Platelet Rich Fibrin (PRF) on enhancement of osseous and associated tissue healing has been substantiated well in literature.
- Trial name
- NCT05005377
- Testing
- Socket Preservation with Platelet-Rich Fibrin, Socket Preservation with Freeze-Dried Bone Allograft
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Correction of Nasolabial Folds and Lip Augmentation
PREVELLE Shape (CX002) Dermal Filler Protocol
The purpose of this study was to assess PREVELLE Shape (CX002), with respect to safety and efficacy for one year following treatment, for correction of facial nasolabial folds and when applied as an intradermal implant for lip…
- Trial name
- NCT00764257
- Testing
- PREVELLE Shape, Restylane
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mentor Worldwide, LLC
Repeated Implantation Failure
The Study of the Relationship Between TWEAK/Fn14, JAK/STAT3 and IDO in the Immune Microenvironment of Endometrium in Repeated Implantation Failure
The purpose of this study is to find out the possible relationship among TWEAK/Fn14, JAK/STAT3 and IDO as well as their roles in the dysfunction of immune micro-environment of endometrium in people diagnosed as repeated…
- Trial name
- NCT02967419
- Testing
- No Intervention
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ZhangTao
Peri-Implantitis, Soft Tissue
Association of Keratinised Mucosa Around Implants and Teeth With Peri-implant/Periodontal Disease and Soft Tissue Conditioning
Lack of keratinised mucosa around dental implants and teeth is associated with plaque accumulation and worse tissue conditions. However, there is lack of data on the influence of the presence/lack of keratinised mucosa on the…
- Conditions
- Peri-Implantitis, Soft Tissue, Bone Gain
- Trial name
- NCT03501537
- Testing
- Free gingival graft obtained from the palate and debridement of the peri-implant lesion
- Where
- Spain
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Peri-Implantitis, Peri-implant Mucositis
Efficacy of Air-polishing on Pain Perception and Compliance Rate
Implants have become a popular and widely used treatment option for treating partial and total edentulism. As the number of implants placed increases, so does the incidence of peri-implant mucositis and peri-implantitis.
- Trial name
- NCT06109701
- Testing
- Debridement with ultrasonic device and scaling with plastic curettes, Debridement with erythritol based air-polishing powde
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Thick Gingival Margin to Tooth Restoration
Aesthetic Outcomes of Single Tooth Implant Using Metal Ceramic Restorations With Either Zirconia or Titanium Abutments
Different studies have proposed the use of zirconia abutments to improve the aesthetic outcomes in the anterior sextant, however the results have been inconclusive.
- Trial name
- NCT02315794
- Testing
- SPI®ART, SPI®EASY
- Where
- 2 sites in Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Firenze and Siena, Napoli, Italy