Clinical trials: IVF
Polycystic Ovarian Syndrome
In Vitro Maturation (IVM) for Polycystic Ovary Syndrome (PCOS)
This pilot study will be a prospective investigation to study the efficacy and safety of In-Vitro Maturation (IVM) for women with Polycystic Ovarian Syndrome (PCOS). There will be 10 subjects total in this Study.
- Trial name
- NCT01237106
- Testing
- IVM
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Reproductive Associates
Infertility, Obesity
Metabolomic Embryo Profiles of Obese in Vitro Fertilization (IVF) Patients and Their Relationship With Polycystic Ovary Syndrome (PCO)
The present study aims to elucidate if there is a metabolomic profile alteration in the embryos of obese women in order to understand if the reduced implantation rate observed in these patients is directly related to this factor.
- Trial name
- NCT01448863
- Testing
- Culture medium metabolomic analysis
- Where
- 2 sites in Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility Low Over Reserve, IVF
BPA Levels Relationship With IVF/ICSI Outcomes in Low Ovarian Reserve
The relationship between BPA elevation in urine, blood, and follicle fluid and embryo quality, IVF/ICSI outcomes.
- Conditions
- Infertility Low Over Reserve, IVF, Infertility, Female
- Trial name
- NCT04654598
- Testing
- BPA levels
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Nefise Nazlı YENIGUL
Infertility
Role of Heparin in Poor Responders Undergoing In Vitro Fertilisation
The addition of heparin increases pregnancy outcome parameters in poor responders undergoing In Vitro Fertilisation (IVF)
- Trial name
- NCT01315093
- Testing
- Heparin, Low-Molecular-Weight, no heparin
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Placenta Diseases, IVF
Ultrasound Diagnosis of Placental and Umbilical Cord Anomalies in Singleton Pregnancies Resulting From In-vitro Fertilization
Objectives: to identify which type of placental and umbilical cord abnormalities are more common in IVF singleton pregnancies; to investigate if heterologous fertilization is an additional risk factor for the development of these…
- Trial name
- PLACENTA (NCT05172674)
- Testing
- ultrasound according routine antenatal care
- Where
- Italy
- Volunteers
- 587 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
IVF-ET
Impact of Expressive Touching During Embryo Transfer
Infertile individuals report psychiatric symptoms and that their levels of anxiety and depression are significantly higher than in fertile controls .Thus,this study aimed to determine the effect of expressive touching during…
- Trial name
- NCT06590636
- Testing
- Expressive touching
- Where
- Palestinian Territories
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Fertility
Multi-Center, Randomized, Open-Label, Parallel Group Study of a Vaginal Micronized Progesterone Tablet (Endometrin®) Compared to Crinone 8% Vaginal Gel in Female Patients Undergoing In-Vitro Fertilization (IVF)
This multicenter, randomized, open-label study will be performed in approximately 990 healthy females undergoing IVF. Each study center will follow their study center standard practice for IVF unless otherwise noted in this…
- Trial name
- NCT00296478
- Testing
- Endometrin, Crinone
- Volunteers
- 1,211 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
ARTIFICIAL INTELLIGENCE (AI) APPLICATIONS IN REPRODUCTIVE MEDICINE
ARTIFICIAL INTELLIGENCE IN REPRODUCTIVE MEDICINE
Many studies have been published investigating the use of AI as an unbiased, automated approach to embryo assessment. This review will summarize the recent AI advancements in the IVF field.
- Trial name
- AI in ART (NCT05699850)
- Testing
- ARTIFICIAL INTELLIGENCE (AI)
- Where
- 2 sites in Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
In Vitro Fertilization
The Influence of Dopamine Agonist Cabergoline on Oocyte Maturation
The dopamine agonist cabergoline inhibits phosphorylation of the vascular endothelial growth factor receptor-2(VEGFR-2), which prevent vascular endothelial growth factor (VEGF) overexpression and reduce the severity of Ovarian…
- Trial name
- NCT01065376
- Testing
- the timing cabergoline administration
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Infertility (IVF Patients), BMI
BMI Versus Body Fat Percentage - Which is the Better Predictor of Fertility Outcomes in IVF Cycles?
The goal of this prospective observational cohort study is to evaluate whether body composition measured using bioelectrical impedance analysis (BIA) (including measures of body fat% and visceral fat) serve as a better predictor…
- Conditions
- Infertility (IVF Patients), BMI, Bioelectrical Impedance Analysis, IVF Outcomes
- Trial name
- NCT07765368
- Testing
- Measurement of BIA (Body Fat and Visceral Fat Percentage)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Infertility
LH Hormone Pulsation in the Luteal Phase in GnRH Antagonist IVF Cycles Triggered by GnRH Agonist for Final Oocyte Maturation
Monitoring the LH pulsatility during the Luteal phase in GnRH antagonist IVF cycles triggered by GnRH agonist for final oocyte maturation.
- Trial name
- NCT02449642
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Metformin, Prediabetes
Effect of Metformin on Healthy Live Birth in Women With Prediabetes
To evaluate the efficacy and safety of metformin pretreatment on reproductive outcomes in infertile women with prediabetes.
- Conditions
- Metformin, Prediabetes, In-Vitro Fertilization
- Trial name
- MELT-PreDM (NCT06064669)
- Testing
- Metformin pretreatment before ovarian stimulation, Metformin pretreatment before endometrial preparation for frozen embryo transfer
- Where
- China
- Volunteers
- 988 people, healthy volunteers welcome
- Sponsor
- Shandong University
Infertility
DNA Analysis of Discarded Media Drops From the Clinical IVF Cycles
Performing DNA analysis of discarded media drops from the clinical IVF cycles completed in our Center
- Trial name
- NCT03717441
- Testing
- chromosome numeration of embryos
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Reproductive Medicine
Vitamin D Status
The Impact of Vitamin D Status on in Vitro Fertilization (IVF) Outcomes
Infertility is a common and psychologically devastating problem for 20% of Canadian couples. Approximately, 20% of infertile couples are diagnosed with unexplained infertility and left without an explanation for their inability…
- Trial name
- NCT01348594
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Infertility, Female
Androgenic Profile Following Controlled Ovarian Stimulation
In this study the investigators will try to discover whether there is a difference for any of the stimulation preparations - recombinant FSH + recombinant LH (pergoveris \& luveris) vs.
- Trial name
- NCT02992808
- Testing
- recombinant gonadotropins, HP-HMG
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
IVF Outcomes
Comparison of Two Protocols in Frozen Embryo Transfer
This randomized clinical trial evaluates two different endometrial preparation protocols-hormone replacement therapy (HRT) and natural cycle-for frozen embryo transfer (FET) in infertile women undergoing assisted reproductive…
- Trial name
- NCT07003373
- Testing
- hormone replacement therapy (HRT) group
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Malihe Mahmoudinia
Infertility
Autologous Endometrial Coculture (AECCT)
The purpose of this study is to determine if the use of Autologous Endometrial Coculture (AECC) in young in vitro fertilization (IVF) patients with poor ovarian reserve improves pregnancy outcome.
- Trial name
- AECCT (NCT01472861)
- Testing
- AECC (Autologous endometrial coculture), no endometrial biopsy or Autologous endometrial coculture (AECC) performed
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infertility, Infertility, Female
A Proof of Concept Study of Serum Progesterone Levels for IVF/ICSI Following HCG Trigger for Oocyte Maturation
This study will determine the rise of progesterone levels after human chorionic gonadotrophin (hCG) trigger in stimulated cycles IVF/ICSI
- Conditions
- Infertility, Infertility, Female, IVF, hCG
- Trial name
- NCT04417569
- Testing
- hCG, Ultrasound, Blood test
- Where
- United Arab Emirates
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Midazolam Overdose
Measurement of Midazolam Levels in Follicular Fluid
To determine the impact of Midazolam levels in follicular fluid on morpho-kinetics and morpho-genetics. The reason to measure Midazolam levels in larger size follicles in this study is to maximize the chances to get a mature…
- Trial name
- NCT03049293
- Testing
- Midazolam
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC