Clinical trials: IVF
IVF
Direct Thawing of Vitrified Human Blastocyst
There are more than million frozen embryo transfers around the world each year; a faster, safer, and cheaper method can save a significant amount of money for patients undergoing IVF treatment worldwide.
- Trial name
- NCT06322823
- Testing
- direct thawing, Vitrification
- Where
- Hong Kong
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Pregnancy Complications, IVF
The START Clinic: a Feasibility Study
This is a study of the feasibility of a translational research clinic for pregnancies conceived by in vitro fertilisation (IVF).
- Conditions
- Pregnancy Complications, IVF, Fetal Growth Retardation, Preeclampsia
- Trial name
- START (NCT04488861)
- Testing
- Non-interventional cohort study
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Manchester Academic Health Science Centre
IVF Outcomes, Stress Levels
Virtual Reality Use in Assisted Reproductive Technology
The study will examine the effect of exposure to virtual reality on stress levels and pregnancy rates, in infertile women undergoing in vitro fertilization embryo transfer
- Trial name
- NCT04394962
- Testing
- Virtual reality
- Where
- Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Dr cliff Librach
Role of Vitamin D in IVF for Better Outcome
Vitamin D as a Prognostic Marker on Assisted Reproductive Technologies Outcomes.
Studying the effect of Vitamin D administration on assisted reproductive outcomes in women undergoing Intra Cytoplasmic Sperm Injection (ICSI) by giving a dose of vitamin D and determining the effect of this dose on both the…
- Trial name
- NCT05091203
- Testing
- Vitamin D
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infertility, Female, Web
Responsive Web-based Roadmap (InT-mAp) in Infertility Treatment
Infertility affects approximately 48 million couples and 186 million individuals globally, and it has biological, psychosocial, and economic problems in couples.
- Conditions
- Infertility, Female, Web, Anxiety, IVF
- Trial name
- InT-mAp (NCT05890625)
- Testing
- On going treatment, InT-mAp
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Effectiveness of Isoamyl-2-cyanoacrylate With and Without Ethiodized Oil in Occluding Hydrosalpinx Prior to IVF
Hysteroscopic Tubal Occlusion Using Amacrylate With or Without Lipidol in Patients With Hydrosalpinx Prior to IVF
Hysteroscopic tubal occlusion using iso-amyl- 2-cyanoacrylate with or without Ethiodized oil (Lipidol) in patients with hydrosalpinx prior to IVF
- Trial name
- NCT06130072
- Testing
- iso-amyl- 2-cyanoacrylate., iso-amyl- 2-cyanoacrylate mixed with Ethiodized oil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Infertility, IVF
The Importance of Embryo Transfer Day Progesterone Value in Natural Cycle Frozen Embryo Transfers and the Evaluation of the Effect of Rescue Therapy on Pregnancy Outcomes in Patients With Low Progesterone Levels
Thanks to recent advances in clinical practice and laboratory, embryo cryopreservation has become the first-line procedure in assisted reproductive technology.
- Conditions
- Infertility, IVF, Progesterone
- Trial name
- NCT05481684
- Testing
- Normal Progesterone group, Low Progesterone group
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
IVF, PCOS
Single vs. Group CAPA-IVM Culture of Cumulus-oocyte Complexes
Oocyte in vitro maturation (IVM) is a minimal-stimulation ART with reduced hormone-related side effects and risks for the patients.
- Conditions
- IVF, PCOS, IVM
- Trial name
- NCT04562883
- Testing
- The way of Cumulus-oocyte complexes (COC) culture
- Where
- Vietnam
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
IVF
Effect of Reducing the Oxygen Concentration From 5% to 2% on ICSI Outcome
To assess the effect of reducing the oxygen concentration from 5% to 2% on Intracytoplasmic sperm injection (ICSI) outcome.
- Trial name
- NCT05924048
- Testing
- Reducing the Oxygen Concentration From 5% to 2%
- Where
- Egypt
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- International Islamic Center for Population Studies and Research
Infertility, In Vitro Fertilization
Virtual Reality for Acute Pain and Anxiety During Egg Retrieval for in Vitro Fertility Treatment
This study is a comparison between the current standard practice of performing a transvaginal oocyte retrieval (TVOR) with paracervical block (PCB) and a relatively recently developed technology of virtual reality that is added…
- Conditions
- Infertility, In Vitro Fertilization, IVF, ART
- Trial name
- NCT05438238
- Testing
- Oncomfort
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, Female, AMH
AMHR2 Polymorphism in Blood and Granulosa Cells in Unexplained Infertility
There are various known parameters for assessing ovarian reserve, including ovarian volume, antral follicle count, follicle stimulating hormone (FSH) and Inhibin B at the beginning of the menstrual cycle, as well as…
- Conditions
- Infertility, Female, AMH, IVF
- Trial name
- NCT05592730
- Testing
- AMHR2 polymorphism in blood, AMHR2 polymorphism in granulosa cell
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Polycystic Ovary Syndrome, Infertility
Progesterone Primed Ovarian Stimulation Protocol Versus Antagonist Protocol for PCO Patient
this study is designed to compare the Progesterone primed ovarian stimulation protocol versus the antagonist protocol as a method to stimulate PCO patients in ICSI cycles to decrease cost and decrease OHSS.
- Conditions
- Polycystic Ovary Syndrome, Infertility, IVF
- Trial name
- NCT05847660
- Testing
- Progesterone antagonist, conventional antagonist protocol
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Non-viable Oocytes, Extra Spermatozoa
Evaluation of Discarded Laboratory Pathological Specimens and Media
The researchers propose to investigate the causes, incidence, and time-related events of chromosomal and physiologic abnormalities as they relate to patient diagnosis, fertility drugs utilized, and in vitro laboratory culture…
- Conditions
- Non-viable Oocytes, Extra Spermatozoa, Seminal Fluid, Granulosa Cells
- Trial name
- NCT01219439
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Pain, Postoperative, IVF
OPU-LUX: Virtual Reality for Pain and Anxiety Management During Oocyte Pick-up
In vitro fertilization (IVF) cycles are increasingly performed worldwide. Transvaginal oocyte pick-up (OPU) is a painful part of IVF. OPU in polyfollicular IVF is usually performed under sedation and pain relief.
- Trial name
- OPU-LUX (NCT05830513)
- Testing
- Virtual Reality
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Luzerner Kantonsspital
ART, IVF
Health in Childhood Following Assisted Reproductive Technology
The purpose of this trial is to investigate the metabolic and cardiovascular health in children aged 6-8 years born after in-vitro fertilization with frozen embryo transfer
- Conditions
- ART, IVF, Cardiovascular Risk Factor, Hypertension
- Trial name
- HiCART (NCT03719703)
- Where
- Denmark
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Anja Bisgaard Pinborg
Infertility, Female, IVF
The Difference Between POSEIDON Group 3 and Group 4 as Regards IVF
prospective observational study over POSEIDON group 3 and POSEIDON group 4 with antagonist protocol for clinical pregnancy rate outcomes
- Trial name
- POSEIDON (NCT05778331)
- Testing
- Antagonist protocol for induction of ovulation
- Where
- Egypt
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Infertility, IVF
Quality of Human Embryos in IVF, Culturing in Differentiated Oxygen
The goal of this clinical trial is to evaluate the importance of differential O2 tension to the developing embryos. As a secondary aim, we investigate the levels of reactive oxygen species (ROS) in spent media from the developing…
- Conditions
- Infertility, IVF, Embryo
- Trial name
- NCT05737381
- Testing
- Differential oxygen tension
- Where
- Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
IVF
Higher Dose of Rekovelle in Oocyte Donors
Higher numbers of oocytes have not been shown to increase implantation or live newborn rates, but higher numbers of oocytes are likely to be beneficial in certain treatments.
- Trial name
- REKO15 (NCT04778358)
- Testing
- Follitropin Delta, Recombinant
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
IVF, Pregnancy
Evaluation of the Relationship Between Oxidative Stress and Human Reproduction
The aim of the study is to investigate the role of oxidative stress in female infertility and the relationship between the stress as it is illustrated by questionnaires, serum markers, follicular fluid markers, and ovarian…
- Conditions
- IVF, Pregnancy, Oxidative Stress, Fertility Disorders
- Trial name
- OxidStressHR (NCT05575739)
- Testing
- Measurement of oxidative stress levels (Malondialdehide, glutathione disulphate, total antioxidant capacity, superoxide dismutase and carbonylated proteins )
- Where
- Romania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Calla IVF Center
Infertility, Infertility, Female
Serum Progesterone Levels on the Day of Frozen Embryo Transfer (FET) and Pregnancy Outcomes
Frozen embryo transfer (FET) cycles have become more common in recent years due to a push towards elective single embryo transfer (SET).
- Conditions
- Infertility, Infertility, Female, IVF
- Trial name
- ProFET (NCT04170517)
- Testing
- Measurement of serum progesterone on the day of FET
- Where
- United Kingdom
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- CARE Fertility UK