Clinical trials: IVF
Use of GnRH Agonist Alone for Luteal Phase Support in Fresh IVF Cycles
GnRH Agonist for Luteal Phase Support.
Objective To assess the the efficacy of luteal support with GnRH agonist in patients undergoing IVF in antagonist-based hcg triggered cycles compared with standard luteal support with progesterone.
- Trial name
- NCT05484193
- Testing
- GnRH agonist, Progesterone
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
IVF Treatment
Follicle Size and Oocyte Development
Studies have shown that the follicles greater in diameter was most likely to have a mature oocyte that was capable of fertilization and best suited for development into a high-quality embryo.
- Trial name
- AMJH (NCT03660813)
- Testing
- Follicle measurment, Ovitrelle ( Hcg 250 mcg), Decapeptyl ( GnRH Agonist 0.1 mg*2 )
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
IVF
Serum Progesterone on the Day of Thawed Embryo Transfer and Pregnancy Rate After an Artificial Endometrial Preparation
To determine if different serum Progesterone levels on FET day are associated with different clinical pregnancy rates (CPR), and if increasing dosage of vaginal Progesterone in cases of lower serum Progesterone level on FET day…
- Trial name
- NCT04278508
- Testing
- Progesterone
- Where
- Israel
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
IVF
Comparative Study Between Fresh and Frozen Embryo Transfer in PCOS Patients Undergoing IVF Treatment
The objective of our study is to compare in vitro fertilization (IVF) outcomes between fresh embryo transfer (ET) and frozen-thawed ET in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT05167838
- Testing
- fresh embryo transfer, Frozen embryo transfer
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cairo University
IVF, LOW OVARIAN RESPONSE
Comparison of Triggers in Double Ovarian Stimulation (DuoStim).
This study aims to investigate the efficacy of 3 different trigggers used for final maturation in the second ovarian stimulation in double stimulation protocol (aGnRH and hCG-rec vs. aGnRH only vs. hCG-rec only).
- Trial name
- COTRID (NCT05321511)
- Testing
- Triptorelin acetate (a-GnRH), Ovitrelle® (hCG), Decapeptyl 0.1 mg® (a-GnRH) and Ovitrelle® (hCG) used together
- Where
- 4 sites in Spain
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Infertility, Infertility, Female
A Proof of Concept Study of Serum Progesterone Levels for IVF/ICSI Following HCG Trigger for Oocyte Maturation
This study will determine the rise of progesterone levels after human chorionic gonadotrophin (hCG) trigger in stimulated cycles IVF/ICSI
- Conditions
- Infertility, Infertility, Female, IVF, hCG
- Trial name
- NCT04417569
- Testing
- hCG, Ultrasound, Blood test
- Where
- United Arab Emirates
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility, IVF
Health of IVF Versus IVM Children (FM-BABIES)
The investigators conduct a follow up of our randomized controlled trial (RCT) to investigate the development of children born from In-vitro fertilization (IVF) and In-vitro maturation (IVM), in order to give strong evidence…
- Conditions
- Infertility, IVF, IVM
- Trial name
- FM-BABIES (NCT04296357)
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Placenta Diseases, IVF
Ultrasound Diagnosis of Placental and Umbilical Cord Anomalies in Singleton Pregnancies Resulting From In-vitro Fertilization
Objectives: to identify which type of placental and umbilical cord abnormalities are more common in IVF singleton pregnancies; to investigate if heterologous fertilization is an additional risk factor for the development of these…
- Trial name
- PLACENTA (NCT05172674)
- Testing
- ultrasound according routine antenatal care
- Where
- Italy
- Volunteers
- 587 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Infertility, Male, IVF
BPA Levels Relationship With IVF/ICSI Outcomes in Patients With Male Factor
Association between blood and semen BPA levels and ICSI outcomes in patients with male factor
- Trial name
- NCT05224284
- Testing
- BPA levels
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Infertility, IVF
Effects of E2, P4 and LH Levels on the Day of Transfer and Endometrial Cavity Thickness on Implantation Success in Patients With Frozen-thawed Embryo Transfer Cycle
Thanks to recent advances in clinical practice and laboratory, embryo cryopreservation has become the first-line procedure in assisted reproductive technology.
- Conditions
- Infertility, IVF, Progesterone
- Trial name
- NCT04769401
- Testing
- Normal Progesterone group, Low Progesterone group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
COVID-19, IVF
The Impact of the Previous Exposure to Covid-19 Virus Infection on the Outcome of ICSI Cycles
Whilst the global COVID-19 pandemic is still evolving and there are many unknowns about the long-term effects of the virus on fertility and pregnancy, we found ourselves in need to offer some evidence-based guidance, that's why…
- Trial name
- NCT05198401
- Testing
- covid-19
- Where
- Egypt
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
Infertility, IVF
Addition of Dydrogesterone to the Luteal Phase Support After Fresh Embryo Transfer
Randomized controlled study, open label to compare effectiveness of addition of dydrogesterone 20mg to the standard luteal phase support treatment after fresh embryos transfer.
- Trial name
- NCT04408144
- Testing
- Dydrogesterone 10mg Oral Tablet
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Laniado Hospital
IVF
Dual Trigger, Urinary HCG or Recombinant HCG, Which is the Best !?
a comparative study among dual trigger, urinary HCG and recombinant HCG regarding the outcome of ICSI- antagonist cycles
- Trial name
- NCT04265495
- Where
- Bahrain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
IVF, PCOS
Effect of GM-CSF on CAPA-IVM System Success Rates in PCOS
In-vitro maturation (IVM) of human oocytes obtained from minimally stimulated or unstimulated ovaries offers a more "patient friendly" treatment option than the conventional Assisted Reproductive Technology (ART) treatment with…
- Conditions
- IVF, PCOS, IVM
- Trial name
- NCT04774432
- Testing
- GM-CSF group, Control group
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Infertility, Female, IVF
RCT to Assess the Impact of Microbiome Status in Infertile IVF Patients at Their First IVF/ICSI Cycle
Although the endometrium has been traditionally considered free of bacteria, recent studies have documented the presence of an endometrial microbiome.
- Trial name
- NCT04686357
- Testing
- EMMA/ALICE
- Volunteers
- 1,018 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
IVF
Uterine Lesions and Their Association to Invitro Fertilization(IVF) or Intracytoplasmic Sperm Injection(ICSI) Outcome
1. To study the effect of uterine wall , intracavitary , cervical as well as cervical canal lesion on the outcome of IVF/ICSI cycle. 2. To establish a score for prediction of IVF/ICSI cycle success .
- Trial name
- NCT04939376
- Testing
- IVF
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Assiut University
Polycystic Ovary Syndrome, IVF
Follicular Fluid Raman Shifts and IVF Outcomes
This study intends to collect about 150 cases of follicular fluid samples from PCOS and non-PCOS infertility patients undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles (in clinical…
- Trial name
- NCT04838535
- Testing
- Raman spectrum
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
HCG; IVF; Pregnancy Rates; ART; Chorionic Gonadotropin
Low-dose HCG as an Adjunct to Ovarian Stimulation in Subfertile Women Undergoing ART
The objective of this prospective randomized clinical trial is to investigate whether the addition of low-dose hCG to a short GnRH-agonist protocol for IVF and ovarian stimulation with rFSH from the onset of the follicular phase…
- Trial name
- HCG (NCT03423537)
- Testing
- hCG
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Infertility, Assisted Reproductive Technology
Does the Embryo Transfer Technique Affect the Success of in Vitro Fertilization?
Prospective, open, randomized, parallel, two-arm trial to compare the clinical pregnancy rate between most commonly used two embryo transfer techniques: trial followed by transfer technique and afterloading technique
- Conditions
- Infertility, Assisted Reproductive Technology, IVF
- Trial name
- NCT03756857
- Testing
- Afterload Transfer, Trial followed by transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Acibadem Kadiköy Hospital
Infertility, Female, Polycystic Ovary Syndrome
Letrozole for Frozen Embryo Transfer (FET) in Patients With Polycystic Ovary Syndrome (PCOS)
To offer patients with oligomenorrhoea or amenorrhoea an alternative to frozen embryo transfer in an artificial cycle, endometrial preparation using letrozole may be a valuable option.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, IVF, Ovulation Disorder
- Trial name
- LEFT (NCT04002635)
- Testing
- Letrozole, estradiol valerate
- Volunteers
- healthy volunteers welcome
- Sponsor
- CRG UZ Brussel