Clinical trials: IVF Treatment
Women With Recurrent Implantation Failure in IVF
Use of GM-CSF Treatment in Recurrent Implantation Failure
The purpose of this study is to determine whether in Assisted Reproductive Technologies the treatment with GM-CSF, a growth factor working on stem cells, may improve the pregnancy rate and pregnancy outcome in patients…
- Trial name
- NCT01715974
- Testing
- GM-CSF group, CONTROL
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Fertility Disorders, Infertility (IVF Patients)
The Effect of Mindfulness-Based Lifestyle Support Program on Infertile Women
This randomized controlled trial aimed to determine whether a mindfulness-based lifestyle support program would improve quality of life, lifestyle, mindfulness, attention and meditation level and treatment outcomes in women…
- Trial name
- NCT06799507
- Testing
- Interventions Based on Mindfulness, Routine clinical procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dokuz Eylul University
Infertility, Female
Melatonin Study Between Diminished and Normal Responder in IVF
Poor sleep quality may lead to increase in oxidative stress and free radicals which in turn may decrease the reproductive function.
- Trial name
- NCT03117725
- Testing
- Melatonin adminstration
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bundang CHA Hospital
Subclinical Hypothyroidism, Infertility
Levothyroxine Treatment and IVF Outcomes in Women With Subclinical Hypothyroidism: A Target Trial Emulation
Subclinical hypothyroidism (SCH) is defined by elevated thyroid-stimulating hormone (TSH) with normal free thyroxine (fT4) levels.
- Conditions
- Subclinical Hypothyroidism, Infertility, Assisted Reproductive Technology, In Vitro Fertilization (IVF)
- Trial name
- LESI (NCT07257250)
- Where
- 2 sites in Vietnam
- Volunteers
- 900 people
- Sponsor
- Mỹ Đức Hospital
Infertility, Female
Multicenter, Randomized, Open Label, Parallel Study to Evaluate the Efficacy & Safety of IVF-M HP Inj. vs. Menopur® Inj.
The objective of this study was to demonstrate the non-inferiority of IVFM HP Inj. by evaluating its efficacy versus Menopur® Inj.
- Trial name
- NCT02458768
- Testing
- IVF-M HP Inj., Menopur® Inj.
- Volunteers
- 112 people
- Sponsor
- LG Life Sciences
Infertility, Female, Luteinizing Hormone (LH)
Extra Luteinizing Hormone Improve Embryo Quality in IVF Patients With Low LH During Long GnRH-Agonist Treatment
This randomized controlled trial aims to evaluate whether supplementation with exogenous luteinizing hormone (LH) can improve embryo quality in patients undergoing in vitro fertilization (IVF) with a long gonadotropin-releasing…
- Trial name
- ELH-IVF (NCT07128394)
- Testing
- Recombinant Luteinizing Hormone (rLH), Recombinant Follicle-Stimulating Hormone (rFSH), Gonadotropin-Releasing Hormone Agonist (GnRH-a)
- Where
- China
- Volunteers
- 590 people
- Sponsor
- Nanjing University
Fertilization in Vitro
The Comparison of Granulosa Cell Apoptosis Rates With or Without Luteinizing Hormone Administration in Poor Responders.
In Zeynep Kamil Women and Children's Education and Research Hospital which is a tertiary referral hospital, the investigators perform microdose flare-up gonadotropin-releasing hormone (GNRH) analogue or GNRH antagonist protocol…
- Trial name
- NCT03527823
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sebnem Alanya Tosun
IVF
Endometrial Preparation in Frozen Embryo Transfer Cycles
In order to get optimal pregnancy rates after frozen embryo transfer (FET), the embryo stage and endometrium should be synchronized.
- Trial name
- NCT06181305
- Testing
- estradiol valerate and letrozole, letrozole 2,5 mg tablet
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Rahem Fertility Center
Frozen Embryos
Time - Lapse Analysis of Frozen Embryos
A retrospective analysis of embryo defrost cycles that were rated in the EmbryoScope system and frozen will be performed. The study will examine the possible association between the morphokinetic grading received by these embryos…
- Trial name
- NCT04255641
- Testing
- time lapse analysis
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Infertility
Effect of Treatment With Corifollitropin Alpha in Vitro Fertilization in Patients With Poor Ovarian Response.
Patients who have had or are expected to have a poor ovarian response (POR), because they meet any of the criteria of Bologna, can benefit from ovarian stimulation with 150 mg of alpha Corifollitropin (CFA) (Elonva ®) as single…
- Trial name
- NCT02118051
- Testing
- Ganirelix 0.25 mg., Recombinant choriogonadotropin alfa, Micronized natural progesterone.
- Where
- Spain
- Volunteers
- 234 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Sperm Capacitation
Sperm Capacitation Assay as a Tool to Predict Sperm Potential to Fertilize in IVF Treatment
Our aim is to evaluate the potential of a new laboratory method that measure sperm capacitation to predict fertilization of oocytes in patients that undergo IVF treatments
- Trial name
- NCT00731159
- Testing
- sperm capacitation, biologic
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
IVF, Intracytoplasmic Sperm Injection
Buscopan in Patients Undergoing IVF/Intracytoplasmic Sperm Injection Treatment
To determine if the use of Buscopan in patients undergoing IVF/ICSI treatment with high uterine contraction frequency prior to embryo transfer has a higher live birth rate.
- Trial name
- NCT04751084
- Testing
- Buscopan 20 milligrams/ML Injectable Solution
- Where
- Hong Kong
- Volunteers
- 675 people
- Sponsor
- Chinese University of Hong Kong
Infertility
A Trial Evaluating Autologous Endometrial Co-Culture Versus Conventional Medium in the Treatment of Infertility
One of the main factors in the success of in-vitro fertilization is the quality of the environment of the embryo. In contrast to maternal age, the environment in which the embryo develops is a modifiable factor.
- Trial name
- OvoGEN (NCT01886118)
- Testing
- Endometrial biopsy, Autologous Endometrial Co-Culture, Conventional media culture
- Where
- Canada
- Volunteers
- 207 people
- Sponsor
- Clinique Ovo
Infertility, Female, ART
Impact of COVID-19 on Psychological Status in Case of IVF Interrupted or Postponed
Infertility is a severely distressing experience for many couples. Depression and anxiety are psychological disorders associated with infertility, and they may worsen during infertility treatments.
- Conditions
- Infertility, Female, ART, IVF, COVID-19
- Trial name
- NCT04395755
- Testing
- Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-9 (PHQ-9)
- Where
- Italy
- Volunteers
- 503 people
- Sponsor
- Piazza della Vittoria 14 Studio Medico - Ginecologia e Ostetricia
Infertility, In Vitro Fertilization
Virtual Reality for Acute Pain and Anxiety During Egg Retrieval for in Vitro Fertility Treatment
This study is a comparison between the current standard practice of performing a transvaginal oocyte retrieval (TVOR) with paracervical block (PCB) and a relatively recently developed technology of virtual reality that is added…
- Conditions
- Infertility, In Vitro Fertilization, IVF, ART
- Trial name
- NCT05438238
- Testing
- Oncomfort
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
IVF Treatment
Self-operated Endo-vaginal Telemonitoring (SOET), an Economic and Patient-empowered Method for Ovarian Stimulation for In-vitro Fertilization (IVF)
The SOET project introduces a new strategy for routine follow-up of follicle growth during the hormonal treatment phase of an in-vitro fertilization (IVF) treatment cycle.
- Trial name
- SOET (NCT01781143)
- Testing
- Perform Echo at home.
- Where
- 4 sites in Belgium
- Volunteers
- 121 people
- Sponsor
- University Hospital, Ghent
IVF, IVF Treatment
A New Website for Australian IVF Patients: 'Evidence-based IVF'
IVF 'add-ons' are extra procedures, techniques, or medicines offered alongside standard IVF treatments, often marketed to improve success rates. Examples include EmbryoGlue, endometrial scratching, and acupuncture.
- Conditions
- IVF, IVF Treatment, IVF-ET, IVF/ICSI
- Trial name
- NCT06885151
- Testing
- Evidence-based IVF website content, Control
- Where
- Australia
- Volunteers
- 1,217 people
- Sponsor
- University of Melbourne
Infertility
Use of Granulocyte Colony-stimulating Factor for the Treatment of Recurrent Implantation Failure in IVF Patients
The investigators use granulocyte colony-stimulating factor (GCSF) for the treatment of recurrent implantation failure in IVF patient with cause unknown or due to thin endometrium.
- Trial name
- NCT01315470
- Testing
- neupogen administration for women with recurrent IVF failure
- Where
- 2 sites in Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Adenomyosis, Infertility
Adenomyosis and Pregnancy Outcomes in Women Undergoing Assisted Reproductive Technology Treatment
Rationale: A rising number of adenomyosis cases are being diagnosed in women in the age group of 30 to 40 years. This is due to a combination of better diagnostic imaging techniques and a higher number of women delaying the…
- Conditions
- Adenomyosis, Infertility, ART, Pregnancy Loss
- Trial name
- AdAPT-ART (NCT05418140)
- Testing
- Ultrasound diagnosis of adenomyosis
- Where
- 9 sites in United Kingdom
- Volunteers
- 828 people
- Sponsor
- CARE Fertility UK
Infertility
Efficacy of Endocell® vs Conventional Medium in the Treatment of Infertility
The aim of this study is to demonstrate the efficacy of a single embryo transfer at blastocyst stage (Day 5) after co-culture on Autologous Endometrial Cell Culture (AECC) versus transfer of a single embryo at Day 3 after culture…
- Trial name
- NCT01058603
- Testing
- - Conventional culture medium for IVF, - Endocell®
- Where
- France
- Volunteers
- 720 people
- Sponsor
- Laboratoires Genévrier