Clinical trials: IVF-ET
Female Infertility
Female Fertility, Environmental Agents and Stress Oxidant
Synthetic products used in industrial, pharmaceutical, agro-alimentary or agricultural fields are found in our environment. Thus, humans could be simultaneously exposed to several of these pollutants.
- Trial name
- FERTENOX (NCT04866329)
- Testing
- Blood sample, Urine sample, Follicular fluid and granulosa cells sample
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Tours
Infertility, IVF Treatment
Early Follicular Supplementation of Ganirelix in IVF 2004
Our goal was to investigate whether early follicular supplementation of the GnRH antagonist to the flexible GnRH antagonist protocol, has a potential to improve IVF-ET clinical results
- Trial name
- NCT00461422
- Testing
- Ganirelix
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Obesity, Maternal
The Application of HCG in Luteal Support for Frozen Embryo Transfer in Ovulation Cycle of Obese Women
This study aims to explore whether the application of low-dose HCG in luteal support can improve the pregnancy outcomes of natural cycle frozen embryo transfer in obese patients
- Trial name
- NCT07633002
- Testing
- Human Chorionic Gonadotropin
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Shandong University
Infertility
Extended High Dose Letrozole Regimen Versus Short Low Dose Letrozole Regimen as an Adjuvant to GnRH Antagonist Protocol in the Management of Poor Responders Undergoing IVF-ET
The aim of this randomized controlled trial is to compare the efficacy of extended high dose letrozole regimen (5 mg /day for the first 5 days of cycle and 2.5 mg/day for the subsequent 3 days ) with short low dose letrozole…
- Trial name
- NCT01219153
- Testing
- Extended high dose letrozole regimen /GnRH antagonist protocol, Short low dose letrozole regimen /GnRH antagonist protocol
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Cairo University
Embryo/Fetus Death, Blastocyst Disintegration
Assessment of Implantation Potential of Embryos by Time-lapse Technology
1. Culture conditions of developing embryos are highly controlled in the Embryoscope and are monitored by Time-lapse videography to produce 3D images at different stages.This cannot be done under conventional culture conditions.
- Conditions
- Embryo/Fetus Death, Blastocyst Disintegration, Aneuploidy, Complication of Implant
- Trial name
- Embryoscope (NCT01760278)
- Testing
- recombinant Follicle Stimulating Hormone (rFSH)
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bloom IVF and Fertility Centre
Infertility
Salpingectomy Versus Aspiration of Hydrosalpingeal Fluid Prior to IVF-ET
The aim of this randomized controlled trial is to compare the efficacy of ultrasound guided aspiration of hydrosalpingeal fluid with salpingectomy in the management patients with ultrasound visible hydrosalpinges undergoing…
- Trial name
- NCT02008240
- Testing
- Needle aspiration of hydrosalpinx, Salpingectomy
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Aljazeera Hospital
Poor Ovarian Response
Effect of Recombinant Human Growth Hormone Injection on the Clinical Outcome of POR in Patients Undergoing IVF/ET
Observe the clinical efficacy and safety of Recombinant Human Growth Hormone Injection assisted in the treatment of the patients with poor ovarian response in vitro fertilization and embryo transfer.
- Trial name
- NCT02801591
- Testing
- Conventional ovarian stimulation proctol without rhGH
- Where
- 2 sites in China
- Volunteers
- 240 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Luteal Hormone Supplementation in In-vitro Fertilization, Embryo Transfer
Phase 3 Trial to Evaluate the Efficacy and Safety of COL-1620 Vaginal Progesterone Gel
The primary objective of this trial is to demonstrate the non-inferiority of the clinical pregnancy rate per embryo transfer to the historical standard value in in-vitro fertilization (IVF)/embryo transfer (ET) cycles in Japan…
- Trial name
- NCT01863680
- Testing
- COL-1620, Gonadotropin-releasing hormone (GnRH) analogue, Follicle-stimulating hormone (FSH)
- Where
- 5 sites in Japan
- Volunteers
- 178 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Female Infertility
Phase IV Study to Evaluate the Efficacy and Safety of Fang Le Shu Compared to Guo Na Fen for Controlled Ovarian Stimulation in Infertile Women Undergoing in Vitro Fertilization-embryo Transfer (IVF-ET).
The aim of this randomized, open-label, active-controlled, parallel-group, multicenter, phase IV study is to assess the efficacy and safety of Fang Le Shu versus Guo Na Fen used for controlled ovarian stimulation in infertile…
- Trial name
- NCT06921395
- Testing
- Fang Le Shu (Follitrope), Guo Na Fen (Gonal-F)
- Where
- China
- Volunteers
- 248 people
- Sponsor
- LG Chem
Diminished Ovarian Reserve
The Effeciency of NMN in Improving IVF/ICSI-ET Pregnancy Outcomes in Patients With DOR
The purpose of the study is to understand the effect of nicotinamide mononucleotide (NMN) on patients with diminished ovarian reserve and the outcomes of IVF/ICSI-ET.
- Trial name
- NCT06426355
- Testing
- NMN
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Preterm Birth
Prolonged Progesterone to Prevent Preterm Birth From IVF - ET
To investigate the incidence of preterm birth in IVF fresh embryo transplantation cycle patients after prolonged vaginal progesterone treatment
- Trial name
- NCT05787509
- Testing
- Progesterone Sustained-release vaginal gel
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Infertility
Successive Doses of GnRH Agonist Versus Single Dose of GnRH Agonist to Trigger Ovulation in Hyper-responders
The aim of this randomized controlled study is to compare the efficacy of three successive doses of a GnRH agonist ( administered 36 , 24 and 12 hours before oocyte retrieval ) with a single dose of a GnRH agonist ( administered…
- Trial name
- NCT07569315
- Testing
- Successive doses GnRH agonist, Single dose GnRH agonist
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Bedaya Hospital
Infertility
Endometrial Injury and IVF-ET Outcome
Implantation of the human embryo is the limiting factor in the success of invitro-fertilization and embryo transfer(IVF-ET).We wanted to find out whether creating a local injury to the endometrium in the non-transfer cycle would…
- Trial name
- NCT00796341
- Testing
- PIPELLE ENDOMETRIAL SAMPLING
- Where
- India
- Volunteers
- 99 people
- Sponsor
- Bangalore Assisted Conception Centre
Diminished Ovarian Reserve (DOR), Infertility (IVF Patients)
RCT Study on the Effect of ETN on Live Birth Rate in DOR Patients Undergoing IVF-ET
The goal of this clinical trial is to examine the effect of ETN on live birth rate in patients with diminished ovarian reserve (DOR) undergoing in vitro fertilizitaion-embryo transfer (IVF-ET).
- Trial name
- ETN-LBR-DOR (NCT07769684)
- Testing
- electro-thumbtack needle (ETN) / thumbtack needle (TN)
- Where
- 4 sites in China
- Volunteers
- 406 people
- Sponsor
- Huazhong University of Science and Technology
Effect on Implantation and Pregnancy Rates
Effect of Seminal Plasma Insemination on Pregnancy Rates After IVF-ET
Seminal plasma insemination into the vaginal vault of patients undergoing IVF-ET increases uterine receptivity.
- Trial name
- NCT01809366
- Testing
- seminal plasma insemination
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Assaf-Harofeh Medical Center
Infertility (IVF Patients), Infertility
Standardization of Variable Conditions of Embryo Transfer Into the Uterine Cavity in the Procedure of Medically Assisted Procreation in Humans
The EFECT study is a clinical trial designed to determine whether improving the consistency of embryo transfer procedures can increase pregnancy success in patients undergoing frozen embryo transfer (cryoET).
- Conditions
- Infertility (IVF Patients), Infertility, ART
- Trial name
- EFECT (NCT07396181)
- Testing
- Embryocase, Embryopass, Embryocase+Embryopass
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Przychodnia Lekarska nOvum Katarzyna Kozioł, Piotr Lewandowski sp.k.
Focus of Study Instead
Endometrial Injury Increases Implantation and Pregnancy Rates
Objective To evaluate the effect of local injury to the endometrium for implantation, pregnancy and live birth rates in ICSI -ET cycles with recurrent implantation failure. Design Randomized controlled clinical study.
- Trial name
- NCT01340560
- Testing
- Endometrial biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Infertility, Female
Multicenter, Randomized, Open Label, Parallel Study to Evaluate the Efficacy & Safety of IVF-M HP Inj. vs. Menopur® Inj.
The objective of this study was to demonstrate the non-inferiority of IVFM HP Inj. by evaluating its efficacy versus Menopur® Inj.
- Trial name
- NCT02458768
- Testing
- IVF-M HP Inj., Menopur® Inj.
- Volunteers
- 112 people
- Sponsor
- LG Life Sciences
Pregnancy, Thrombophilia
The Effect of Heparin in Treatment IVF-ET Failure
Embryo transfer failure is defined as ≥3 IVF-embryo transfer failures without pregnancy . In spite of transfer of 3 good quality embryos , just 20-30% of women undergoing IVF will achieve ongoing pregnancy .
- Trial name
- NCT01214772
- Testing
- heparin
- Where
- Iran
- Volunteers
- 86 people
- Sponsor
- Yazd Medical University
IVF-ET
Impact of Expressive Touching During Embryo Transfer
Infertile individuals report psychiatric symptoms and that their levels of anxiety and depression are significantly higher than in fertile controls .Thus,this study aimed to determine the effect of expressive touching during…
- Trial name
- NCT06590636
- Testing
- Expressive touching
- Where
- Palestinian Territories
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University