Clinical trials: IVf
Pregnancy, Ovarian
Clinical and Live Birth Rates After Following Long Antagonist Protocol Versus Long Agonist Protocol
A prospective study of the evaluation of the clinical IVF (in vitro fertilization) results after following Long Antagonist protocol for Controlled Ovarian Stimulation (COS) versus following Long Agonist protocol
- Trial name
- NCT03693534
- Testing
- Clinical Pregnancy Rate
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Infertility
Adding Insulin to IVF Culture Media Significantly Improve Outcome
Add insulin to a single step culture media for IVF embryo culture from day 0 to day 5/6 of In Vitro culture and detect the the effect upon embryo quality and implantation potential.
- Trial name
- NCT02420171
- Testing
- Adding insulin to In Vitro culture media
- Where
- 2 sites in Egypt
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Ibn Sina Hospital
Ovarian Function at Advanced Reproductive Age
Co Enzyme Q10 Improves IVF Outcome in With Advanced Reproductive Age
The goal of the investigators research is to explore energy production of the ovarian follicle in older reproductive age women at the time of oocyte retrieval.
- Trial name
- NCT01659788
- Testing
- Coenzyme Q10 concomitant treatment
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Brugada Syndrome, Long QT Syndrome 3
Worm Study: Modifier Genes in Sudden Cardiac Death
Quest for modifier genes associated with ventricular arrhythmias in presence of a cardiac sodium channel gene (SCN5A-delPhe1617) mutation.
- Trial name
- NCT02014961
- Testing
- Dermal biopsy, Gastro-intestinal questionnaire, Whole-exome sequencing
- Where
- Netherlands
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
IVF, LOW OVARIAN RESPONSE
Comparison of Triggers in Double Ovarian Stimulation (DuoStim).
This study aims to investigate the efficacy of 3 different trigggers used for final maturation in the second ovarian stimulation in double stimulation protocol (aGnRH and hCG-rec vs. aGnRH only vs. hCG-rec only).
- Trial name
- COTRID (NCT05321511)
- Testing
- Triptorelin acetate (a-GnRH), Ovitrelle® (hCG), Decapeptyl 0.1 mg® (a-GnRH) and Ovitrelle® (hCG) used together
- Where
- 4 sites in Spain
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Infertility
An Advanced Decision Support Tool, Opt-IVF for Clinical Ivf Practice
Aim: A Clinical trial to determine the effectiveness of using the proposed decision support tool for each patient's customized optimal drug dosage profile.
- Trial name
- NCT05564702
- Testing
- traditional drug treatment, Opt-IVF predicted dosage
- Where
- India
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Stochastic Research Technologies LLC
Aneuploidy, Pregnancy
The Effect of Co Enzyme Q10 Together With Fertility Drugs on Pregnancy Outcome of in Vitro Fertilization
The goal of our research is to increase live birth rates in infertile women and to reduce the incidence of aneuploidy leading to miscarriage and trisomies.
- Conditions
- Aneuploidy, Pregnancy, Miscarriage
- Trial name
- CoQ10-IVF (NCT01048385)
- Testing
- Coenzyme Q10 concomitant treatment
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Ovarian Hyperstimulation
Progesterone Diurnal Rhythm During Ovarian Stimulation for IVF
To evaluate the influence of circadian rhythm on progesterone levels during follicular phase of natural cycle and during follicular phase of controlled ovarian stimulation during IVF.
- Trial name
- NCT02975713
- Where
- United Arab Emirates
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
PCOS GnRH Antagonist and GnRH Agonist IVF/ICSI Cycles
In Vitro Fertilization Outcomes of Two Treatment Protocols in Women With Polycystic Ovary Syndrome
Outcomes of IVF/ICSI cycles of women with PCOS undergoing Gonadotropin Releasing Hormone (GnRH) agonist and GnRH Antagonist fixed protocol.
- Trial name
- PCOS and ivf (NCT01354275)
- Testing
- To compare the IVF/ICSI outcomes of GnRH Antagonist cycle versus GnRH agonist cycle, GnRH Antagonist
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bulent Haydardedeoglu
Infertility
Prospective, Randomized Trial Comparing ICSI to Insemination for Non-Male Factor Patients Undergoing PGT-A
Intracytoplasmic sperm injection (ICSI) is a procedure performed during in vitro fertilization (IVF) in which a single sperm is injected directly into an oocyte.
- Trial name
- NCT05548101
- Testing
- ICSI
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Texas Fertility Center
IVF-ET
Impact of Expressive Touching During Embryo Transfer
Infertile individuals report psychiatric symptoms and that their levels of anxiety and depression are significantly higher than in fertile controls .Thus,this study aimed to determine the effect of expressive touching during…
- Trial name
- NCT06590636
- Testing
- Expressive touching
- Where
- Palestinian Territories
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Infertility
Effect of Addition of Aromatase Inhibitor to Ovarian Stimulation Therapy in IVF Treatment
This project seeks to determine whether estradiol suppression achieved with adjuvant treatment with an aromatase inhibitor improves end-follicular and midluteal phase parameters during IVF.
- Trial name
- RIOT-A (NCT02946684)
- Testing
- Letrozole
- Where
- 4 sites in Denmark
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Sven O. Skouby
Infertility, Female, Polycystic Ovary Syndrome
Letrozole for Frozen Embryo Transfer (FET) in Patients With Polycystic Ovary Syndrome (PCOS)
To offer patients with oligomenorrhoea or amenorrhoea an alternative to frozen embryo transfer in an artificial cycle, endometrial preparation using letrozole may be a valuable option.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, IVF, Ovulation Disorder
- Trial name
- LEFT (NCT04002635)
- Testing
- Letrozole, estradiol valerate
- Volunteers
- healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Mood Disorders
Gonadal Steroid Manipulation and Personality Characteristics: Association With Mood Fluctuations and in Vitro Fertilization (IVF) Outcomes
The current study's primary aim is to investigate the association between neuroendocrine fluctuations and mood disorders by monitoring mood states over distinct hormonal phases during in-vitro-fertilization (IVF) treatment.
- Trial name
- IVF (NCT01032421)
- Testing
- IVF procedure
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Immunomodulatory Drugs, Killer-cell Immunoglobulin-like Receptors (KIRs)
Effect of Immunomodulatory Treatment on IVF (in Vitro Fertilization) Outcomes in Patients With KIR AA Genotype
The aim of the study is to investigate the immune cause of recurrent implantation failure (RIF) and the role of immunomodulatory treatment in IVF (in vitro fertilization) patients that have a KIR AA genotype.
- Conditions
- Immunomodulatory Drugs, Killer-cell Immunoglobulin-like Receptors (KIRs), KIR Alleles (KIR AA)
- Trial name
- NCT06264206
- Testing
- Killer-cell immunoglobulin-like receptors (KIRs) testing
- Where
- Romania
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Calla IVF Center
Embryo
Effect of Degranulation Needle With Different Diameters on the Rate Good Embryo in IVF
Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality.
- Trial name
- NCT03810040
- Testing
- 140 microns denuding pipette, 150 microns denuding pipette
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Abortion, Spontaneous, Abortion, Habitual
Intralipid for Recurrent Miscarriage
Intralipid infusion can improve the outcome in NK cells positive females with history of recurrent miscarriages undergoing IVF/ICSI cycles.
- Trial name
- NCT01788540
- Testing
- Intralipid
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
VITAMIN D Disorders
Serum Vitamin D Level and Its Association With Ovarian Reserve and IVF Outcome
Vitamin D has a major play in bone and calcium metabolism. Vitamin D deficiency (below 20 ng/ml) has also been linked to adverse health outcomes such as malignancy, cardiovascular disease, immune functioning, and glucose…
- Trial name
- NCT02317718
- Testing
- monitor reproductive outcome
- Where
- United Arab Emirates
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fakih IVF Fertility Center
Infertility, Female, Pain, Postoperative
Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Control for Oocyte Retrieval
In this research study we want to learn more about how effective certain medications are at reducing pain after oocyte (egg) retrieval surgery and how effective they are at reducing the time between the retrieval and discharge…
- Trial name
- NCT03073980
- Testing
- IV Acetaminophen, PO Acetaminophen
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Infertility, ART
Automation of the In Vitro Fertilization Laboratory
Enrolled patients will undergo an Assisted Reproductive technology (ART) treatment using intracytoplasmic sperm injection (ICSI, the direct injection of a single sperm cell into an oocyte) as the method of insemination.
- Trial name
- NCT06581068
- Testing
- AURA assisted ART treatment
- Where
- 2 sites in Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Conceivable Life Sciences