Clinical trials: Iatrogenic Disorder
Standard Precautions, Hand Hygiene Behavior
Infection Control Link Nurses Program to Improve Compliance With Standard Precautions, Hand Hygiene, and Prevent Healthcare-Associated Infections
The goal of this clinical trial is to learn if Infection Control Link Nurses (i.e., clinical nurses providing direct patient care with an interest and expertise in infection control practices) are effective in improving nurses'…
- Conditions
- Standard Precautions, Hand Hygiene Behavior, Healthcare Associated Infections
- Trial name
- INFECTION (NCT06857825)
- Testing
- Implementation of Infection Control Link Nurses (ICLNs)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
Craniotomy Surgery, Preventive Health Care
The Effect of Bundle Application on Surgical Site Infection
Surgical site infections (SSI) are the most common complications after surgical operations and are in the top three in Healthcare Associated Infections (HIE).
- Trial name
- NCT06724354
- Testing
- The Surgical Site Infections Precaution Package Form includes the parameters that should be applied to patients before, during and after surgery.
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Ventilator Associated Pneumonia
Single-used Versus MultiPlE-used Endotracheal suCtIon cAtheters in Mechanically ventiLated ICU Patients
In low and middle-income countries, open endotracheal suction catheters are used multiple times to perform suctioning due to limited resources [1,2].
- Trial name
- SPECIAL-ICU (NCT06207513)
- Testing
- Suction Circuit Flushing with Chlorhexidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Immobility Syndrome, Deep Venous Thrombosis
Bedside Bike Early Mobilization Program for Inpatients
Hospital immobility leads to serious complications including muscle loss, weakness, delirium, pressure ulcers, and blood clots. Despite being medically stable, hospitalized patients spend over 90% of their time in bed due to…
- Conditions
- Immobility Syndrome, Deep Venous Thrombosis, Delirium, Hospital Acquired Condition
- Trial name
- BB-STEP (NCT07281638)
- Testing
- Bedside Bike
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Hand Hygiene Training, Infection Prevention and Control
Effectiveness of an Edge AI-based Augmented Reality System for Hand Hygiene Training: a Multi-centre, Mixed-methods Cluster Randomised Controlled Trial
This multi-centre, mixed-methods cluster randomised controlled trial (cRCT) aims to evaluate the effectiveness of an edge artificial intelligence (AI)-based augmented reality (AR) training and assessment system for improving hand…
- Conditions
- Hand Hygiene Training, Infection Prevention and Control, Healthcare-Associated Infections (HAIs), Health Education
- Trial name
- HANDHEART (NCT07280026)
- Testing
- Instructional Video + Scanner Feedback, Edge AI-based AR Hand Hygiene Training System
- Where
- 3 sites in China, Hong Kong
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Hospital Infection, Standardized Antibiotic Prescribing Ratio (SAR)
InPART RX - Epicenters
InPART Rx is a collaborative research study to measure the impact of a planned quality improvement initiative to reduce unnecessary antibiotic prescribing by the Hospital Medicine Service through a process of receiving…
- Trial name
- InPART RX (NCT07368660)
- Testing
- Messaging Hospitalists, Usual Care
- Where
- 4 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Emory University
Covid19, Personal Protective Equipment
Rational Use of Personal Protective Equipment During COVID-19 Pandemic
This study aims to improve the personal protective equipment (PPE) used while treating patients with COVID-19, to protect staff and avoid cross-infection of patients.
- Trial name
- RUPERT (NCT04712045)
- Testing
- New PPE, Old PPE
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Hospital Acquired Condition
The Effect of Real Time Analytics on Adverse Events Among Hospitalized Patients
This study will examine the effect of providing nurses with continuous, remote, real-time monitoring of their patient's vital signs and MEWS scores using the BAS on the occurrence of adverse events, admissions to the ICU…
- Trial name
- NCT04674098
- Testing
- The Beat Analytics System (BAS)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bob Topp
Facial Nerve Injuries, Mandibular Fractures
Safety-zone Approach and Facial Nerve Preservation in Transbuccal-accessed Fixation of Mandibular Fractures
The goal of this study is to investigate the efficacy of a safety-zone that is anatomically landmarked on the face of patients with mandibular fractures that are approached transbuccally (through cheek) on postoperative…
- Conditions
- Facial Nerve Injuries, Mandibular Fractures, Surgical Incision
- Trial name
- NCT07807813
- Testing
- Landmarking Safety-zone
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Ventilator Associated Pneumonia
Risk Factors and Common Preventive Measures for Ventilator Associated Pneumonia in Patients With Severe Traumatic Brain Injury
The primary objective of this study is to assess the incidence of VAP in patients with TBI and to identify risk factors for developing VAP in this specific patient population (types of co-injuries in patients with multiple trauma…
- Trial name
- NCT03266380
- Testing
- observational
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Septic Shock, Severe Trauma
REAnimation Low Immune Status Markers
The fact that sepsis disrupts immune system homeostasis by inducing an initial cytokine storm, that participates to occurrence of organ failures and early death, followed by a compensatory anti-inflammatory response leading to…
- Conditions
- Septic Shock, Severe Trauma, Severe Burn, Major Surgery
- Trial name
- REALISM (NCT02638779)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Health Care Associated Infection
Clinical Trial Evaluating Chlorine e6 Derivative-mediated Antimicrobial Photodynamic Therapy as a Treatment for Denture Stomatitis
Objective: This randomized clinical trial assessed antimicrobial Photodynamic Therapy (aPDT) mediated by Photodithazine (PDZ) to treat patients with denture stomatitis (DS).
- Trial name
- NCT04532060
- Testing
- Nystatin, Antimicrobial Photodynamic Therapy
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Patient With Influenza Like Illness
Effect of Influenza Vaccination of Healthcare Workers (HCW) on the Risk of Influenza in Patients Hospitalized in Short Stays Units
Hospital acquired influenza is associated with significant morbidity and mortality in hospitalized patients notably elderly patients. Vaccination of HCW is recommended to prevent influenza transmission in healthcare setting.
- Trial name
- NCT02198638
- Testing
- A nasal swab
- Where
- 2 sites in France
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Elderly, Iatrogenic Drug Risk
Iatrogenic Drug Risk in People Over 75, With or Without Cognitive Disorders, From an Inventory of Their Family Pharmacy
Many hospitalizations or emergency room visits are due to problems of iatrogenic medication, especially in elderly patients who are very often polymedicated. Moreover, they are more at risk because of fragility.
- Trial name
- RIMPAP (NCT03686943)
- Testing
- Family pharmacy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Coronavirus Infections, Healthcare Associated Infection
NO Prevention of COVID-19 for Healthcare Providers
Thousands of healthcare workers have been infected with SARS-CoV-2 and contracted COVID-19 despite their best efforts to prevent contamination. No proven vaccine is available to protect healthcare workers against SARS-CoV-2.
- Trial name
- NOpreventCOVID (NCT04312243)
- Testing
- Inhaled nitric oxide gas
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Clostridioides Difficile Infection, Healthcare Associated Infection
Evaluation of GeoHAI Implementation
Geographic Information Systems (GIS) and spatial analysis have become important tools in public health informatics but have rarely been applied to the hospital setting.
- Trial name
- NCT05612672
- Testing
- GeoHAI
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pneumonia, Ventilator Associated, Closed System Suction Catheter
Time Interval for Changing Closed System Suction Catheters, Effect on Ventilator Associated Pneumonia
The purpose of this study was to compare the incidence of ventilator-associated pneumonia between two groups of patients randomised to have closed system suction catheter changes every 24 hours and patients having closed system…
- Trial name
- NCT00447109
- Testing
- Closed system suction
- Where
- Australia
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Functional Decline, Hospitalization-associated Disability
Incidence and Risk Factors for Hospitalization-Associated Disability
This prospective cohort study aims to determine the incidence of hospitalization-associated disability and its association with risk factors at the patient level and with care and hospital processes.
- Conditions
- Functional Decline, Hospitalization-associated Disability, Iatrogenic Disease
- Trial name
- NCT02572999
- Testing
- Not applicable (observational design)
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Catheter-Associated Infection
Clinical Evaluation of Copesilcup
Healthcare-associated infections (HAIs): HAIs are a problem for all institutions and countries worldwide. Currently, one of the main infections is catheter-associated urinary tract infection (CAUTI).
- Trial name
- Copesilcup (NCT07530328)
- Testing
- PEGylated Silicone Urinary Catheter with Copper Nanoparticles (COPESILCUP), Control Device
- Where
- Chile
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- WMAS SpA
Iatrogenic Disease
Rationalisation of Polypharmacy by the Geriatric Consultation Team
Polypharmacy is a common problem in elderly, leading among others to increased adverse drug events. The aim of this pilot study was to evaluate whether a systematic medication evaluation by a geriatric consultation team using the…
- Trial name
- RASP-GCT (NCT02165618)
- Testing
- Medication review, based on but not limited to the RASP list
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven