Clinical trials: Iatrogenic Injury
Multi-drug Resistant Gram-negative Bacilli Colonization
Multidrug Resistant Gram-negative Bacilli Colonization and Infection in Burn
This is a prospective observational study to determine the role of colonization and identify the timing of development of drug resistance in multidrug resistant Gram-negative bacilli (MDR-GNB) causing infection among critically…
- Trial name
- NCT02653157
- Testing
- MDR-GNB
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute Renal Failure, Infection
Efficacy and Safety of Ethanol Lock Solution in Prevention of Catheter Related Bloodstream Infection for Patients Suffering Acute Renal Failure, and Hospitalized in Intensive Care Unit. A Multi-Center, Randomized, Versus Placebo, Double Blinded Clinical Trial
The primary objective of the study is to demonstrate the efficacy of 60% ethanol lock solution in preventing major catheter related infections in critically ill patients.
- Trial name
- ELVIS (NCT00875069)
- Testing
- Ethanol
- Where
- France
- Volunteers
- 1,460 people
- Sponsor
- University Hospital, Clermont-Ferrand
Coagulopathy, Nosocomial Pneumonia
Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma
The purpose of this study is to determine the effect of antioxidant vitamins (vitamins C and E) on the development of coagulation derangements and nosocomial pneumonia after severe trauma in patients.
- Trial name
- NCT01897792
- Testing
- Vitamin C, Vitamin E, Saline (for Vitamin C)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Alabama at Birmingham
Ventilator-Induced Lung Injury, Ventilatory Failure
"Lung Barometric Measurements in Normal And in Respiratory Distressed Lungs"
Little is known about how lung mechanics are affected during the very early phase after starting mechanical ventilation. Since the conventional method of measuring esophageal pressure is complicated, hard to interpret and…
- Conditions
- Ventilator-Induced Lung Injury, Ventilatory Failure, Ventilator Lung, Ventilation Therapy; Complications
- Trial name
- LUNAR (NCT04484727)
- Testing
- PEEP-step method
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Göteborg University
Ventilator Acquired Pneumonia, Central Line Associated Blood Stream Infections (CLABSI)
Evidence-Based Nursing to Reduce Adverse Events Regarding Ventilator Associated Pneumonia, Pressure Injuries and Central Line Bloodstream Infection in Intensive Care Unit in Bangladesh
Quality of care is crucial for preventing adverse events such as infection in the intensive care units (ICUs). The most common ICU-acquired infections include pneumonia such as Ventilator Associated Pneumonia (VAP), Pressure…
- Conditions
- Ventilator Acquired Pneumonia, Central Line Associated Blood Stream Infections (CLABSI), Pressure Ulcer (PU), Medical Device Related Pressure Ulcer (MDRPU)
- Trial name
- EBP in Nursing (NCT07299799)
- Testing
- Education with EBP, This is a pre- and post- quasi-experimental study.
- Where
- 2 sites in Bangladesh, Japan
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Traumatic Wound, Infective Wound
The Effect of OASIS Ultra on Critical Sized Wound Healing
The aim of this study is to evaluate the speed and quality with which OASIS® Ultra (Healthpoint Biotherapeutics; Fort Worth, Texas) increases wound healing in the critical sized defect.
- Conditions
- Traumatic Wound, Infective Wound, Iatrogenic Critical Sized Wound Defects, Wound Healing
- Trial name
- NCT01848821
- Testing
- OASIS Ultra, Wound VAC Standard Therapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Cardiovascular Disease, Healthcare Associated Infectious Disease
Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery (HAI)_2
The investigators will conduct qualitative interviews of hospital personnel regarding HAI prevention practices, and use coded data from these interviews to assist in developing standardized practices.
- Conditions
- Cardiovascular Disease, Healthcare Associated Infectious Disease, Sternal Superficial Wound Infection, Deep Sternal Infection
- Trial name
- NCT02073760
- Testing
- There is no intervention. The investigators are interviewing cardiac surgery staff with knowledge of infection prevention.
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Aorto-iliac Occlusive Disease (AIOD), Visceral Artery Occlusive Disease (VAOD)
GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis Post-Market Clinical Follow-Up (PMCF) Observational Registry (RE-PROVE)
Collect real-world post-market clinical follow-up data on subjects treated with the Reduced Profile GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis (Reduced Profile VBX Stent Graft-BXB)
- Conditions
- Aorto-iliac Occlusive Disease (AIOD), Visceral Artery Occlusive Disease (VAOD), Isolated Artery Aneurysms (IAA), Trauma or Iatrogenic Vessel Injury
- Trial name
- NCT07279649
- Testing
- Reduced Profile GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis (Reduced Profile VBX Stent Graft-BXB)
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- W.L.Gore & Associates
Iatrogenic Esophageal Perforation
Endoscopic Management Of Iatrogenic Esophageal Perforation After Laparoscopic Upper Gastrointestinal Surgery
The investigators included all patients who were presented to General Surgery Department with Iatrogenic Esophageal Perforation after Laparoscopic Upper Gastrointestinal Surgery at Zagazig University hospital between (December…
- Trial name
- NCT05781022
- Testing
- endoscopic repair of iatrogenic esophageal perforation
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Zagazig University
Ventilator-Associated Pneumonia (VAP), Inha'le'd
Inhaled Colistin to Prevent Ventilator-Associated Pneumonia in Patients With Acute Brain Injury
Ventilator associated pneumonia is the most common manifestation of hospital acquired infections in ICU. The incidence of ventilator-associated pneumonia in patients receiving mechanical ventilation is as high as 20% -71%, which…
- Trial name
- NCT06819462
- Testing
- Inhaled colistin, Inhaled 0.9% sodium chloride
- Where
- China
- Volunteers
- 444 people
- Sponsor
- Southeast University, China
Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection
Impact of Nurses' Behavior Change and Evidence-Based Practice Implementation on Quality Indicators in Intensive Care Units in Low- and Middle-Income Countries
Study title: Impact of nurses' behavior change and implementing evidence-based practice to improve quality indicators in intensive care units in low-and middle-income countries Background and Rationale: Quality care is crucial…
- Conditions
- Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection, Pressure Ulcers (Hospital-acquired Pressure Injuries), Prolonged Intensive Care Unit Length of Stay
- Trial name
- NCT07397364
- Testing
- Evidence based practices bundles of care
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Respiratory Tract Diseases, Respiratory Tract Infections
Assesment of the Endotracheal Tube Cuff Pressure Values in ICU Pateints Before and After Training Seminar
There is no accepted standard for the frequency of monitoring endotracheal tube cuff pressures (ETCP). the investigators plan on comparing two strategies for monitoring ETCP in mechanically ventilated patients.
- Conditions
- Respiratory Tract Diseases, Respiratory Tract Infections, Pneumonia, Ventilator-Associated, Ventilator-Induced Lung Injury
- Trial name
- NCT03401463
- Testing
- traning seminar
- Where
- Poland
- Volunteers
- 188 people
- Sponsor
- Jagiellonian University
Ventilator Associated Pneumonia
Antibiotic Prophylaxis for Early Ventilator-associated Pneumonia in Neurological Patients
This study seeks to assess whether coma patients really benefit from the use of antibiotics as a prophylactic for reducing the incidence of early ventilator-associated pneumonia in this population group.
- Trial name
- NAVPRO (NCT01118403)
- Testing
- Sultamicillin
- Where
- Colombia
- Sponsor
- Hospital Pablo Tobón Uribe
Traumatic Brain Injury, Deep Vein Thrombosis
Traumatic Brain Injury Associated Radiological DVT Incidence and Significance Study
Whilst deep vein thrombosis (DVT) is common following traumatic brain injury (TBI), optimal timing and safety of pharmacological prophylaxis is uncertain. Paradoxically the harm associated with the occurrence of is also unclear.
- Conditions
- Traumatic Brain Injury, Deep Vein Thrombosis, Acute Lung Injury, Ventilator Associated Pneumonia
- Trial name
- TARDIS (NCT03937947)
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- NHS Lothian
Wound
Povidone-Iodine Versus Chlorhexidine in Surgical Wound Care
This comparison examines the effectiveness of povidone-iodine and chlorhexidine in managing iatrogenic wounds in surgical patients.
- Trial name
- NCT06667089
- Testing
- Povidone-Iodine, Chlorhexidine
- Where
- Spain
- Volunteers
- 107 people
- Sponsor
- University of Jaén
Iron Deposition, Dialysis
Iron Deposits in the Pancreas by MRI Method of Dialysis Patients With Hemosiderosis Iatrogenic (ERDFP)
Recently, a multidisciplinary scientific conference proposed to consider iron overload in dialysis patients as pathological only in the event of demonstration of radiological (in MRI), pancreatic or cardiac ferric deposits.
- Conditions
- Iron Deposition, Dialysis, Iatrogenic Hemosiderosis
- Trial name
- ERDFP (NCT05593068)
- Testing
- MRI
- Where
- France
- Volunteers
- 185 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche