Clinical trials: Idiopathic Epimacular Membrane
Epimacular Membrane
Outcomes Based on the Pre-operative Integrity of IS/OS Junction in Idiopathic Epimacular Membrane Surgery
The aim of this study is to evaluate whether the pre-operative integrity or not of the inner segment (IS) and outer segment (OS) photoreceptoral junction may influence the post-operative visual acuity, the macular morphology…
- Trial name
- NCT04158791
- Testing
- pars plana vitrectomy with epimacular membrane removal and internal limiting membrane peeling
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Idiopathic Epimacular Membrane
Prospective, Single-blind Study Assessing the Benefit/Risk Ratio of Internal Limiting Membrane (ILM) Peeling During Epimacular Membrane (EMM) Surgery (Peeling)
The epimacular membrane (EMM) is a degenerative condition associated with age, with a variable impact on vision. Treatment is surgery based and consists of a vitrectomy followed by a peeling of the epimacular membrane using a…
- Trial name
- Peeling (NCT02146144)
- Testing
- ILM Peeling
- Where
- 6 sites in France
- Volunteers
- 213 people
- Sponsor
- Nantes University Hospital
Cataract, Epiretinal Membrane
Combined 25-gauge Vitrectomy and Cataract Surgery With Toric Intraocular Lens With Idiopathic Epiretinal Membrane.
Toric intraocular lens (IOL) is now widely used for the cataract surgery with preoperative corneal astigmatism. Symptomatic epiretinal membrane (ERM) is often treated with 25-gauge transconjunctival sutureless vitrectomy…
- Conditions
- Cataract, Epiretinal Membrane, Corneal Astigmatism
- Trial name
- NCT02328157
- Testing
- Vitrectomy with cataract surgery and toric IOL, Vitrectomy with cataract surgery and common IOL
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- Kagawa University
Surgery for Cataract, Surgery for and Idiopathic Epiretinal Membrane
Validation of a Prognostic Score for Good Visual Recovery at One Year Following Combined Surgery for Cataract and Idiopathic Epiretinal Membrane
The prevalence of idiopathic epiretinal membranes (ERM) in people over 50 is estimated at 6 to 19%. Even though most cases show very few symptomats, they may induce alterations of the underlying retina and lead to visual…
- Trial name
- PROCATMER (NCT03329976)
- Testing
- measurement of visual acuity
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Epiretinal Membrane
Outcomes of Vitrectomy Combined With Subtenon Triamcinolone Injection for the Idiopathic Epiretinal Membrane
This study compares the anatomical and visual outcomes of patients with idiopathic epiretinal membrane(ERM) treated by vitrectomy and membrane peeling with or without subtenon triamcinolone acetonide injection
- Trial name
- NCT01630876
- Testing
- Vitrectomy only group, Combined therapy group
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yeungnam University College of Medicine
Idiopathic Epiretinal Membranes
Diagnostic Reliability of OCT Biomarkers for iERM
Several optical coherence tomography (OCT) biomarkers with potential to influence postsurgical outcomes after vitrectomy with membrane peeling for idiopathic epiretinal membranes (iERM) have been described in single predictor…
- Trial name
- NCT04997876
- Testing
- Biomarker analysis
- Where
- Austria
- Volunteers
- 136 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Idiopathic Epiretinal Membranes
Clinical Evaluation of With or Without Internal Limiting Membrane Peeling for Idiopathic Epiretinal Membrane Surgery: A Randomized Controlled Trial
Idiopathic epiretinal membrane (ERM) is an age-related degenerative retinal condition. One of the primary treatment approaches is vitrectomy combined with epiretinal membrane peeling.
- Trial name
- NCT07142785
- Testing
- Epiretinal membrane peeling, Epiretinal membrane peeling combined with internal limiting membrane peeling
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Epiretinal Membrane
Vitrectomy Combined With Intravitreal Dexamethasone Implant for Idiopathic Epiretinal Membrane With Macular Oedema
The goal of this clinical trial is to evaluate the efficacy and safety of 25-gauge pars plana vitrectomy combined with intravitreal dexamethasone implant for the treatment of idiopathic epiretinal membrane with cystoid macular…
- Trial name
- NCT06232616
- Testing
- vitrectomy combined with intravitreal dexamethasone implant
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Epiretinal Membrane
Phacoemulsification and 25 Gauge (25G) Vitrectomy Versus Phacoemulsification Only in Idiopathic Epiretinal Membranes
The purpose of the study is to evaluate the difference in Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity, oct retinal thickness and microperimetry in 2 groups of 30 eyes each affected by idiopathic epiretinal…
- Trial name
- NCT01771939
- Testing
- 25-G vitrectomy and phacoemulsification, phacoemulsification (cataract surgery)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Epiretinal Membrane, Macular Edema
Dexamethasone Intravitreal Implant After Vitrectomy For Epiretinal Membrane
The purpose of this study is to evaluate the effect of dexamethasone intravitreal implant (Ozurdex) in combination with pars plana vitrectomy and membrane peeling for idiopathic epiretinal membrane (ERM).
- Trial name
- OZURDEX2 (NCT01410201)
- Testing
- Dexamethasone Intravitreal Implant
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Barnes Retina Institute
Epiretinal Membrane
Microperimetry and Optical Coherence Tomography (OCT) in Idiopathic Epiretinal Membrane
Purpose: To evaluate macular sensitivity and its correlation with visual acuity and Spectral Domain Optical Coherence Tomography (SD-OCT) in eyes with idiopathic epiretinal membrane (ERM).
- Trial name
- NCT01481987
- Testing
- Epiretinal Membrane Surgical treatment
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Epiretinal Membrane, Macular Edema (ME)
Minimal Vitrectomy Surgery for Epiretinal Membrane
This multicenter randomized controlled trial evaluates Minimal Vitrectomy Surgery (MVS) versus conventional vitrectomy for idiopathic epiretinal membrane (ERM).
- Conditions
- Epiretinal Membrane, Macular Edema (ME), Nuclear Cataract
- Trial name
- MVS-ERM (NCT07019896)
- Testing
- Minimal Vitrectomy Surgery, Conventional Vitrectomy
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Peking Union Medical College Hospital
Epiretinal Membrane, Cataract Senile
Mid-term Evaluation of Metamorphopsia in Epiretinal Membrane Surgery
This study evaluates the safety and efficacy simultaneous, trans-conjunctival, 25-Gauge vitrectomy and phacoemulsification with intraocular lens implant in patients with metamorphopsia and visual impairment due to idiopathic…
- Trial name
- NCT03045367
- Testing
- Phacoemulsification, intraocular lens implant, vitrectomy.
- Volunteers
- 30 people
- Sponsor
- Clinica Oculistica dell'Università di Torino
Idiopathic Epiretinal Membranes
Trypan Blue Versus Brillant Blue for Epiretinal Membranes
Membraneppeling alone versus Membranepeeling with Membrane Limitans Interna Pelling using two different Dyes for Epiretinal Membrane Surgery.
- Trial name
- NCT00757380
- Testing
- Trypan Blue, Brillant Blue
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Epiretinal Membrane, Age-related Disease
Comprehensive Review of Retinal Pseudo-Holes: Clinical Presentation, Diagnosis, Pathophysiology, and Management
Retinal pseudo-holes (RPH) are macular abnormalities that mimic macular holes (MH) but lack full-thickness retinal disruption. This systematic review, based on 35 studies, explores their clinical presentation, diagnosis…
- Conditions
- Epiretinal Membrane, Age-related Disease, Idiopathic ERM
- Trial name
- NCT06800638
- Where
- Iran
- Volunteers
- 10 people
- Sponsor
- Mohammad Reza Tokhmehchi
Idiopathic Epiretinal Membrane
Macular Resurfacing Using Autologous ILM Patch Transposition for Idiopathic Epiretinal Membrane
Idiopathic epiretinal membrane is a condition in which abnormal tissue grows on the surface of the retina and can cause blurred vision and distortion.
- Trial name
- NCT07767539
- Testing
- Non-Inverted Autologous Internal Limiting Membrane (ILM) Patch Transposition, Conventional Epiretinal Membrane and Internal Limiting Membrane Peeling
- Volunteers
- 90 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Idiopathic Epiretinal Membrane, Cataract
Surgical Removal of Idiopathic Epiretinal Membrane With and Without the Assistance of Indocyanine Green.
It was the aim of the present study to prospectively compare the functional and morphological outcome of idiopathic epiretinal membrane surgery with and without the assistance of Indocyanine green (ICG).
- Trial name
- NCT00376857
- Testing
- Surgery with and without the aid of Indocyanine Green (ICG)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Regensburg
Proliferative Diabetic Retinopathy
Gene Expression in Patients With Epiretinal Membranes
The purpose of this study was to investigate the expression of selected genes both in epiretinal membranes (ERMs) and peripheral blood mononuclear cells (PBMCs) from patients with primary and secondary epiretinal membranes in…
- Trial name
- NCT01946451
- Where
- Poland
- Sponsor
- Medical University of Silesia
Epiretinal Membranes
Prognostic Factors in Epiretinal Membrane Surgery
Retrospective interventional case series study reporting preoperative clinical and anatomical factors associated with visual recovery 1 year after combined cataract and idiopathic epiretinal membrane surgery.
- Trial name
- NCT02406430
- Testing
- a combined cataract and ERM surgery
- Volunteers
- 142 people
- Sponsor
- Centre Hospitalier Universitaire Dijon