Clinical trials: Idiopathic Gastroparesis
Gastroparesis
An Efficacy and Safety Study of Cisapride in Patients With Chronic Gastroparesis After Failure of Other Treatment Options
The purpose of this study is to assess the effectiveness of cisapride in patients with a primary diagnosis of chronic gastroparesis (a stomach disorder) of unknown cause.
- Trial name
- NCT01281540
- Testing
- Cisapride
- Volunteers
- 20 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Gastroparesis
Pioglitazone for Idiopathic Gastroparesis
The principal objective of this pilot study will be to evaluate whether 8 weeks of treatment of pioglitazone will improve symptoms as measured by the Gastrointestinal Symptom Index (GCSI) in patients with Idiopathic Gastroparesis.
- Trial name
- PIOGAS (NCT04300127)
- Testing
- Pioglitazone 30 mg
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Johns Hopkins University
Gastroparesis, Nausea
Acupuncture Treatment for Gastroparesis: a Pilot Study
Gastroparesis is a disorder characterized by delayed gastric emptying leading to symptoms of nausea, vomiting, bloating, and abdominal pain.
- Conditions
- Gastroparesis, Nausea, Vomiting, Abdominal Pain
- Trial name
- NCT01643577
- Testing
- Acupuncture for gastroparesis, Acupuncture for musculoskeletal pain
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Gastroparesis
Phase 2 Study of Velusetrag in Diabetic or Idiopathic Gastroparesis
This is a multicenter, randomized, double-blind, incomplete block, three period fixed sequence crossover, multicenter, placebo-controlled study.
- Trial name
- NCT01718938
- Testing
- velusetrag dose 1, velusetrag dose 2, velusetrag dose 3
- Where
- 9 sites in United States
- Volunteers
- 34 people
- Sponsor
- Theravance Biopharma
Diabetic Gastroparesis, Idiopathic Gastroparesis
G-POEM for Treatment of Refractory Gastroparesis
This study is performed to assess the efficacy and outcomes of Gastric Per Oral Endoscopic Myotomy "G-POEM" in patients presenting with gastroparesis.
- Conditions
- Diabetic Gastroparesis, Idiopathic Gastroparesis, Gastroparesis Postoperative
- Trial name
- NCT02732821
- Testing
- Gastric Per Oral Endoscopic Myotomy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Johns Hopkins University
Gastroparesis, Diabetic Gastroparesis
Gastroparesis Registry 3
The purpose of this study is to create a new registry of patients with gastroparesis in order to better understand the characteristics of patients with gastroparesis and follow how their condition changes over time.
- Conditions
- Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis
- Trial name
- GpR3 (NCT03680859)
- Where
- 6 sites in United States
- Volunteers
- 406 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis
Biomagnetic Characterization of Gastric Dysrhythmias III
There is a tremendous clinical need for a noninvasive technique that can assess gastric electrical activity and would be repeatable without any exposure to radiation.
- Conditions
- Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis, Total or Partial Gastrectomy
- Trial name
- NCT03176927
- Testing
- magnetogastrogram
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Gastroparesis, Diabetes Complications
To Study the EGG Abnormalities in Healthy Subjects and in Patients With Idiopathic and Diabetic Gastroparesis.
Electrogastrogram (EGG) is a non-invasive method for recording myoelectric activities by placing electrodes on the abdomen surface.
- Conditions
- Gastroparesis, Diabetes Complications, Idiopathic Gastric Motility Disorder, Dyspepsia
- Trial name
- NCT05624034
- Testing
- Electrogastrography
- Where
- India
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Idiopathic Gastroparesis, Diabetic Gastroparesis
Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis
To investigate the safety and efficacy of tradipitant versus placebo in relieving nausea and other symptoms of gastroparesis.
- Conditions
- Idiopathic Gastroparesis, Diabetic Gastroparesis, Gastroparesis
- Trial name
- NCT04028492
- Testing
- Tradipitant, Open Label Tradipitant
- Where
- 36 sites in United States
- Volunteers
- 979 people
- Sponsor
- Vanda Pharmaceuticals
Gastroparesis, Idiopathic Gastric Motility Disorder
Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms
The overall objective of this study is to determine if there are pyloric sphincter abnormalities in patients with gastroparesis symptoms and determine how prevalent these abnormalities are using tests to assess the pyloric…
- Conditions
- Gastroparesis, Idiopathic Gastric Motility Disorder, Diabetic Gastroparesis
- Trial name
- PSAGS (NCT04661215)
- Where
- 5 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Idiopathic Gastroparesis, Diabetic Gastroparesis
Intraluminal Endosonography for Examination of the Structural Changes of the Stomach in Gastroparetic Patients
Patients who empty their stomach slowly may have what we call "Slow gastric emptying" or "gastroparesis". These patients can have some changes in the thickness of their stomach wall.
- Trial name
- NCT01916460
- Testing
- Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Diabetic Gastroparesis, Idiopathic Gastroparesis
Effect of TAK-954 on Gastrointestinal and Colonic Transit in Diabetic or Idiopathic Gastroparesis Participants
The purpose of this study is to evaluate the dose-dependent effects of TAK-954 on gastric emptying time of solids in participants with diabetic or idiopathic gastroparesis assessed by scintigraphy.
- Trial name
- NCT03281577
- Testing
- TAK-954
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Takeda
Gastroparesis, GERD
Domperidone for Relief of Gastrointestinal Disorders
The purpose of this study is to make Domperidone available to patients with gastrointestinal disorders who have failed standard therapy and who might benefit from it.
- Conditions
- Gastroparesis, GERD, Esophagitis, Dyspepsia
- Trial name
- NCT00761254
- Testing
- Domperidone
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Carle Physician Group
Diabetic Gastroparesis, Idiopathic Gastroparesis
A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants With Symptomatic Diabetic or Idiopathic Gastroparesis
The purpose of this study is to assess the safety and efficacy of various dose levels of NG101 compared with placebo in adult participants with gastroparesis during 12 weeks of treatment.
- Trial name
- NCT04303195
- Testing
- NG101
- Where
- 83 sites in United States
- Volunteers
- 161 people
- Sponsor
- Neurogastrx, Inc.
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Idiopathic Gastroparesis, Diabetic Gastroparesis
Open Label Safety Study of Tradipitant in Idiopathic and Diabetic Gastroparesis
This is a multicenter, open label, 3-month safety study with tradipitant in patients with idiopathic and diabetic gastroparesis.
- Conditions
- Idiopathic Gastroparesis, Diabetic Gastroparesis, Gastroparesis
- Trial name
- NCT06836557
- Testing
- Tradipitant
- Where
- 3 sites in Belgium, Germany
- Volunteers
- 17 people
- Sponsor
- Vanda Pharmaceuticals
Gastroparesis
Safety, PK and Efficacy of PCS12852 on Gastric Emptying Rate in Patients With Moderate to Severe Gastroparesis
This is a randomized, double-blind, placebo-controlled study that will compare the effect of 2 different dosage regimens of PCS12852 on gastric emptying time to placebo in both idiopathic gastroparesis (IG) and diabetic…
- Trial name
- MOMENTUM (NCT05270460)
- Testing
- PCS12852
- Where
- 9 sites in United States
- Volunteers
- 25 people
- Sponsor
- Processa Pharmaceuticals
Gastroparesis
The Diabetic and Idiopathic Gastroparesis Efficacy, Safety, and Tolerability (DIGEST) Study
Study 0099 explores the efficacy and safety of multiple doses of velusetrag in the treatment of symptoms in subjects with diabetic or idiopathic gastroparesis.
- Trial name
- DIGEST (NCT02267525)
- Testing
- Velusetrag
- Volunteers
- 233 people
- Sponsor
- Theravance Biopharma
Gastroparesis
A Phase 2 Study of CIN-102 in Adults With Idiopathic and Diabetic Gastroparesis
This is a randomized, double-blind, placebo-controlled Phase 2A study to evaluate safety, efficacy, PK, and dose response of oral CIN-102 in adults with idiopathic and diabetic gastroparesis.
- Trial name
- NCT04026997
- Testing
- CIN-102 Dose 1, CIN-102 Dose 2, CIN-102 Dose 3
- Where
- 19 sites in United States
- Volunteers
- 72 people
- Sponsor
- CinDome Pharma, Inc.
Idiopathic Gastroparesis
Effects of Global Osteopathic Manual Treatments in Patients With Idiopathic Gastroparesis
Global osteopathic manual treatments will decrease the severity score of the Gastroparesis Cardinal Symptom Index tool of patients with idiopathic gastroparesis.
- Trial name
- NCT02232334
- Testing
- Global Osteopathic Manual Treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Kathleen Brannan Brown, Inc.