Clinical trials: Illness, Chronic
Chronic Kidney Diseases
Electronic Decision-support System to Improve Detection and Care of Patients With Chronic Kidney Disease in Stockholm
One in 10 adults in Region Stockholm have chronic kidney disease (CKD), which dramatically increases healthcare costs and the risk of medication errors or adverse health outcomes, including cardiovascular disease and death.
- Trial name
- ALMA-CKD (NCT06386172)
- Testing
- Clinical decision support trigger
- Where
- Sweden
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Chronic Renal Failure
NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED
The purpose of this study is to evaluate the effect of NAC or sodium bicarbonate in preventing the aggravation of renal function in chronic renal failure when enhanced computed tomography scan is checked in emergency room.
- Trial name
- NCT00501475
- Testing
- NAC Bicarbonate
- Where
- 2 sites in South Korea
- Sponsor
- Seoul National University Hospital
Allergic Rhinitis, Chronic Urticaria
Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 1 to Less Than 6 Years Suffering From Allergic Rhinitis or Chronic Urticaria of Unknown Origin
The purpose of this study is to determine the safety of the oral formulation of levocetirizine in children ages 1 to less than 6 years old who suffer from allergic rhinitis or chronic urticaria of unknown origin.
- Trial name
- PAL (NCT00619801)
- Testing
- Levocetirizine
- Where
- 28 sites in United States
- Volunteers
- 173 people
- Sponsor
- UCB Pharma
Indolent Non-Hodgkin Lymphomas/Chronic Lymphocytic Leukemia
Blinatumomab Expanded T-cells (BET) in Indolent Non-Hodgkin Lymphomas/Chronic Lymphocytic Leukemia
Non-Hodgkin CD20 + Indolent Lymphoma (iNHL) and Chronic Lymphatic Leukemia (CLL) are the most frequent neoplasms of B lymphocytes.
- Trial name
- BET2017 (NCT03823365)
- Testing
- Blinatumomab Expanded T-cells (BET)
- Where
- Italy
- Volunteers
- 19 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Palliative Care, Kidney Failure, Chronic
A Communication Tool to Assist Older Adults Facing Dialysis Choices
The purpose of this study is to test the effect of the "Best Case/Worse Case" (BC/WC) communication tool on receipt of palliative care and intensity of treatment at the end of life, quality of life, and quality of communication…
- Conditions
- Palliative Care, Kidney Failure, Chronic, Decision Making, Decision Support Techniques
- Trial name
- NCT04466865
- Testing
- Best Case/Worst Case communication tool training
- Where
- 11 sites in United States
- Volunteers
- 407 people
- Sponsor
- University of Wisconsin, Madison
Chronic Obstructive Pulmonary Disease (COPD), Acute Exacerbation of COPD
Remote Monitoring of COPD Patients Experiencing an Acute Exacerbation Through Health Evaluations Using Wearable Mobile Technology
Chronic obstructive pulmonary disease (COPD) causes about 3 million deaths annually and significantly burdens healthcare systems, costing the EU 38.6 billion euros, largely due to frequent hospitalizations triggered by acute…
- Trial name
- COPD-BREATHE (NCT06890767)
- Testing
- Wearable mobile device, CAT Questionnaire, DHRQ Questionnaire
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- David Ruttens
Chronic Myelocytic Leukemia, Erectile Dysfunctions
A Potential Relationship Between Treatment With Tyrosine Kinase Inhibitors and Erectile Dysfunction in Male Patients With Chronic Myeloid Leukemia
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the presence of the Philadelphia chromosome, resulting in the constitutive activation of the BCR-ABL1 tyrosine kinase.
- Conditions
- Chronic Myelocytic Leukemia, Erectile Dysfunctions, CVD - Cardiovascular Disease, Tyrosine Kinase Inhibitor
- Trial name
- ED2024 (NCT07061145)
- Testing
- Tirosin Kinase Inhibitors
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Chronic Periodontitis
Advantages of Autologous Platelet-Rich Fibrin Membrane on Growth Factor Levels and Periodontal Healing
Platelet rich fibrin is a second generation platelet concentration which contains various growth factors. The aim of this study is to evaluate the clinical and biochemical efficacy of PRF in subjects of chronic periodontitis in…
- Trial name
- NCT02898675
- Testing
- Platelet rich fibrine, Open Flap Debridement
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Chronic Disease, Hypertension
Rehabilitation in Primary Care: A Project to Maximize the Health Status of Adults With Chronic Illness
The purpose of the study is to determine whether occupational therapy and physiotherapy delivered in a primary care setting to adults with chronic illness is effective in improving health.
- Conditions
- Chronic Disease, Hypertension, Back Pain, Obesity
- Trial name
- NCT00229957
- Testing
- Occupational therapy, Physiotherapy, Self-management
- Where
- Canada
- Volunteers
- 303 people
- Sponsor
- Hamilton Health Sciences Corporation
Chronic Kidney Disease With and Without Hemodialysis
Patterns of Cardiac Arrhythmia in Patients With Chronic Kidney Disease
Cardiovascular diseases remain the primary leading cause of death in patients on maintenance hemodialysis accounting for nearly 41% of deaths.
- Trial name
- Arrhythmia (NCT07640919)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Glomerulonephritis, IGA, Renal Insufficiency, Chronic
Leflunomide Plus Low Dose Corticosteroid in Immunoglobulin A (IgA) Nephropathy With Renal Insufficiency
IgA nephropathy is the most common primary glomerulonephritis in the world. Because of the poor treatment effect in advanced patients, it is still the main cause of maintenance dialysis.
- Trial name
- NCT04020328
- Testing
- Leflunomide 20 mg+prednisone 0.5mg/kg/d
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Shenzhen Second People's Hospital
Chronic Kidney Disease
Chinese Observational Prospective Study of Aging Population With Chronic Kidney Disease(C-OPTION)
The study is an observational, multicenter, prospective cohort study aimed at evaluating a 5-year screening programme for chronic kidney disease(CKD) in a population of elderly patients, aged 65 years or more, in China.To analyze…
- Trial name
- NCT03246204
- Volunteers
- 3,000 people
- Sponsor
- Chinese PLA General Hospital
COPD, Healthy
The Effectiveness of Dual-task Exercises in Individuals With COPD
The goal of this clinical trial is to evaluate the effect of dual-task performance on motor and cognitive functions and to determine the effect of dual-task exercises given together with the pulmonary rehabilitation program on…
- Trial name
- NCT05930158
- Testing
- Dual Task Exercises, Pulmonary Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Marmara University
Cancer
Vaccine Therapy in Treating Patients Who Have Undergone a Donor Stem Cell Transplant and Have Cytomegalovirus Infection That Has Not Responded to Therapy
RATIONALE: Vaccines may help the body build an effective immune response to kill cytomegalovirus infections. PURPOSE: This phase I trial is studying the side effects and best dose of vaccine therapy in treating patients who have…
- Trial name
- NCT00509691
- Testing
- cytomegalovirus pp65-specific cytotoxic T lymphocytes, polymerase chain reaction, diagnostic laboratory biomarker analysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Louisville
Biliary Stricture, Chronic Pancreatitis
Covered Metal Stent for Benign Biliary Stricture Caused by Chronic Pancreatitis
Benign biliary strictures caused by chronic pancreatitis can be endoscopically treated with covered self-expandable metal stents (cSEMS).The purpose of the prospective randomized study is to define the optimal duration of…
- Trial name
- NCT01929538
- Testing
- ERCP, covered self-expanding biliary metal stent, 12mm in diameter, covered self-expanding biliary metal stent, 10mm in diameter
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital
Hepatitis B, Chronic
Linkage to Care and Treatment of Chronic HBV Patients
Chronic hepatitis B remains the leading cause of liver related mortality and morbidity globally and locally. Countries have been formulating initiatives to meet the WHO target of eliminating viral hepatitis by 2030.
- Trial name
- HBV (NCT06658678)
- Testing
- Receiving an educational intervention
- Where
- Hong Kong
- Volunteers
- 803 people
- Sponsor
- The University of Hong Kong
COPD
Human Safety of Capsaicin Inhalation Challenge Testing for Young and Older Men
In 2004, the investigators initiated a human Capsaicin inhalation experiment under an Investigational New Drug (IND) protocol approved by the FDA (IND 69,642) and the subject safety procedures instituted and approved by the…
- Trial name
- Capsaicin (NCT01621685)
- Testing
- biological/vaccine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Pulmonary Disease, Chronic Obstructive
Personalized Prediction Strategy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
This is a 3-year longitudinal study designed to establish a personalized prediction and prevention system for acute exacerbations of chronic obstructive pulmonary disease (AECOPD).
- Trial name
- NCT03240315
- Where
- China
- Volunteers
- 442 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
End Stage Renal Disease
An Extension to Assess the Effect of Expanded Dialysis on Patient Reported Symptoms Using LEVIL
Investigators know that many patients who are on dialysis suffer from burden of unwanted symptoms, which can affect quality of life.
- Trial name
- NCT06032208
- Testing
- Theranova Dialyzer
- Where
- 4 sites in Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Insomnia, Insomnia Chronic
Cognitive Behavioral Therapy for Insomnia (CBTi) in Patients With Mental Illness
Insomnia is common in patients with co-morbid mental illness and sleeping difficulties is a frequent complaint in most psychological disorders.
- Conditions
- Insomnia, Insomnia Chronic, Insomnia Due to Mental Disorder, Insomnia, Psychophysiological
- Trial name
- NCT04598425
- Testing
- Cognitive behavioral therapy for insomnia (CBTi)
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Diakonhjemmet Hospital
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