Clinical trials: Image-Guided Surgery
Breast Cancer
Precision Breast Conserving Surgery With Guidance.
From 2021 to 2022, 31 patients with unifocal breast cancer were enrolled for precision breast conserving surgery (PBCS) guided by wire guided localization (WGL) combined with CT guided 3D reconstruction.
- Trial name
- NCT05708664
- Testing
- precision breast conserving surgery guided by wire guided localization combined with MDCT guided 3D reconstruction
- Where
- China
- Volunteers
- 92 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Surgical Education
Patient Specific Virtual Reality for Simulation of Spine Procedures: an Intelligent Image Segmentation, Registration and 3-dimensional Visualization in a Unified Virtual Reality Workflow for Image Guided Therapy, and Education - Physician Testing
The goal of this clinical trial is to learn if patient specific virtual reality (VR) simulations can be used for surgical orthopaedic education in resident and fellow physician populations.
- Trial name
- NCT06714539
- Testing
- Patient Specific Virtual Reality Stimulation
- Volunteers
- 13 people
- Sponsor
- Sunnybrook Health Sciences Centre
Non-Small Cell Lung Cancer, Lymph Node Metastasis
XR-Assisted PET/CT Navigation for Cervical Lymph Node Dissection in Lung Cancer
This single-arm, prospective feasibility study evaluates an Extended Reality (XR) headset-based preoperative surgical planning workflow that fuses 18F-FDG PET metabolic hotspots with CT anatomy on the OpVerse platform, in…
- Conditions
- Non-Small Cell Lung Cancer, Lymph Node Metastasis, Supraclavicular Lymph Node Metastasis
- Trial name
- XR-NeckLND (NCT07593872)
- Testing
- OpVerse XR Surgical Planning Platform with HoloLens HMD, Cervical / Supraclavicular Lymph Node Dissection
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Early Gastric Cancer, Gastric Adenocarcinoma
Image-Guided Platform-Assisted Sentinel Lymph Node Retrieval in Early Gastric Cancer
This prospective, single-center, randomized controlled trial aims to evaluate the clinical effectiveness of an Image-Guided Platform assisted by a deep learning model for sentinel lymph node (SLN) retrieval in patients with early…
- Trial name
- NCT07835087
- Testing
- Image-Guided Retrieval Specimen Platform, Traditional Palpation-Based Sentinel Lymph Node Retrieval
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Beijing Friendship Hospital
Hepatic Carcinoma
Arterial Base Fluorescence Segmental Positive Staining
More and more laparoscopic hepatectomy were performed due to increasing experience, well designed instruments and energy device.
- Trial name
- NCT04266548
- Testing
- Superselective Intra-arterial Hepatic Injection of Indocyanine Green (ICG) for Fluorescence Image-guided Segmental Positive Staining
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- Chang Gung Memorial Hospital
CT-guided Minimally Invasive Procedures e.g. Biopsies
Evaluation of the XACT Robotic System for Image-guided Percutaneous Lung Procedures
This is a prospective, single arm study, to evaluate the safety, effectiveness and usability of the XACT device. Subjects undergoing CT-guided, minimally invasive percutaneous lung procedures in the interventional radiology…
- Trial name
- NCT04612985
- Testing
- XACT Robotic System
- Where
- 2 sites in United States, Israel
- Sponsor
- Xact Robotics Ltd.
Prostate Cancer
Tracer-Guided Surgery for Recurrent Prostate Cancer
ADT with or without robot-assisted PSMA-radioguided surgery for patients with recurrent prostate cancer.
- Trial name
- Trace-II (NCT05555017)
- Testing
- PSMA-radioguided surgery, ADT
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- The Netherlands Cancer Institute
Liver Cancer
Feasibility of a Minimally Invasive Image-Guided Surgery System for Hepatic Procedures
This study was designed to confirm that the surgeon is able to perform accurate liver surface registration including standard liver features used as landmarks during a scheduled laparoscopic liver procedure.
- Trial name
- NCT01238653
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Pathfinder Therapeutics
Colorectal Surgery, Ureter
Randomised Controlled Trial of Fluorescent Urography Using Intravenous Methylene Blue Compared to White Light Alone in Left-sided Colorectal Surgery
This study will see if a blue dye (methylene blue) given into a vein, together with a special camera light, helps surgeons find the left ureter (the tube from the kidney to the bladder) faster during left-sided bowel surgery.
- Trial name
- NCT07835932
- Testing
- Intravenous Methylene blue, Fluorescence Imaging Device for Methylene Blue
- Where
- Hong Kong
- Volunteers
- 108 people
- Sponsor
- Chinese University of Hong Kong
Hearing Loss
Percutaneous Cochlear Implantation: Implementation of Technique
The investigators are studying a new way of doing cochlear implant surgery called "Percutaneous Cochlear Implantation". In this surgery, instead of doing a mastoidectomy where about 30ml of bone is removed, the investigators use…
- Trial name
- PCI-I (NCT01460823)
- Testing
- Percutaneous Cochlear Implantation using image guided surgical techniques
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Vanderbilt University
Oral Cavity Disease
RetracTOR/ Retractor for Image Guided Trans-Oral Surgery
This study aims to demonstrate that a polymer retractor functions the same as a standard metal retractor used during endoscopy and throat surgery.
- Trial name
- NCT06381505
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ryan J. Halter
Pancreatic Cancer
Cetuximab and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed by Surgery
RATIONALE: Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT00599833
- Testing
- cetuximab, 3-dimensional conformal radiation therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 44 people
- Sponsor
- The Christie NHS Foundation Trust
Head and Neck Carcinoma
Near-Infrared Image Guided Surgical Resection With Indocyanine Green in Treating Patients With Head and Neck Cancer
This phase Ib/II trial studies the side effects of near-infrared image guided surgical resection with indocyanine green in treating patients with head and neck cancer.
- Trial name
- NCT03745690
- Testing
- Image-Guided Surgery, Indocyanine Green Drug
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Squamous Cell Carcinoma of the Head and Neck, Oral Cancer
Fluorescence-guided Surgery Using cRGD-ZW800-1 in Oral Cancer
This is a two-staged clinical trial to investigate the feasibility of intraoperative Fluorescence Imaging (FLI) to adequately assess tumor margins in patients with oral cancer using cRGD-ZW800-1.
- Conditions
- Squamous Cell Carcinoma of the Head and Neck, Oral Cancer, Squamous Cell Carcinoma of the Oral Cavity
- Trial name
- GuidedbyLight (NCT04191460)
- Testing
- cRGD-ZW800-1.
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- Erasmus Medical Center
Hepatocellular Carcinoma
Trial Comparing PLA to HIGRT (PROVE-HCC)
This phase II, randomized trial compare Quality of Life for patients with Hepatocellular Carcinoma (HCC) who are not surgical candidates or decline surgery and are treated with Percutaneous Local Ablation (PLA) or…
- Trial name
- PROVE-HCC (NCT03402607)
- Testing
- Percutaneous Local Ablation, Hypofractionated Image Guided Radiation Therapy
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Non Small Cell Lung Cancer
Phase II Image Guided Stereotactic Ablative Radiotherapy for Non-Small Cell Lung Cancer
This study will help researchers learn about the best dose of radiation to be used when treating large early stage non-small cell lung cancer (NSCLC) with a treatment called stereotactic ablative radiotherapy (SABR).
- Trial name
- SABR (NCT02262000)
- Testing
- Image Guided Stereotactic Ablative Radiotherapy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- West Virginia University
Renal Cancer
Prospective Observational Trial of Image-guided Ablative STereotactic bOdy Radiation Therapy for Primary kidNey Cancer: the STONE Trial
The study objective is to evaluate the use of Stereotactic Body Radiotherapy (high dose of radiation in a few fractions) to cure primary renal cancer in those patients that are not indicated to surgery (high risk of…
- Trial name
- NCT07299357
- Testing
- Stereotactic body radiotherapy (SBRT)
- Where
- 2 sites in Italy
- Volunteers
- 53 people
- Sponsor
- Istituto Clinico Humanitas
Gastric Cancer, Sentinel Lymph Node
Fluorescence Image-Guided Lymphadenectomy in Robotic Gastrectomy
Gastric cancer is a worldwide challenge due to its spread, even epidemic in some areas, and the high mortality rates. Lymphadenectomy is considered the fundamental step during radical gastrectomy.
- Trial name
- IG-MIG (NCT03931044)
- Testing
- Image-Guided Robotic Gastrectomy
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- International Study Group on Minimally Invasive Surgery for Gastric Cancer
Aortic Aneurysm, Endoleak
Endoleak Repair Guided by Navigation Technology
The study is aimed at investigating whether repair of endoleak type II can be improved by adding navigation technology. Can this technology increase precision by guiding the needle that punctures through the skin as used during…
- Trial name
- NCT01843322
- Testing
- endoleak repair procedure (navigation technology )
- Where
- Norway
- Volunteers
- 27 people
- Sponsor
- Norwegian University of Science and Technology
Liver Cancer
Evaluation of Image-Guided Liver Surgical System for Resection of Liver Cancer
Image-guided surgery essentially describes the interactive use of medical images during a surgical procedure and is often referred to as a "global positioning" system (GPS) for surgery.
- Trial name
- NCT00782886
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- Pathfinder Therapeutics