Clinical trials: Image-guided Biopsy
Sedation, Interventional Radiology
Evaluation of Ketamine/Midazolam Sedation vs. Fentanyl/Midazolam Sedation for Image-Guided Percutaneous Procedures in Interventional Radiology
This study aims to reduce pain during interventional radiology (IR) procedures, making the experience better for patients. Typically, doctors use medications like fentanyl and midazolam for sedation.
- Conditions
- Sedation, Interventional Radiology, Biopsy, Drainage Procedure
- Trial name
- NCT07040163
- Testing
- ketamine, fentanyl, Midazolam
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- CAMC Health System
Image-guided Biopsy, Complications
Renal Parenchymal Core Needle Biopsy
Percutaneous image-guided parenchymal renal biopsy has been used to detect the different pathologies of renal parenchyma, to define the degree of reversible changes, and to define when the medical treatment fails.
- Conditions
- Image-guided Biopsy, Complications, Kidney Glomerulus
- Trial name
- NCT02758535
- Testing
- coaxial renal biopsy, noncoaxial renal biopsy
- Where
- Iran
- Volunteers
- 166 people
- Sponsor
- Modarres Hospital
Lung Neoplasms, Thoracic Neoplasms
A Multimodality Image-guided System for Peripheral Lung Cancer Diagnosis and Therapy
The goal of this clinical research study is to test the use of a minimally invasive multimodality image-guided (MIMIG) intervention system used for performing a lung biopsy.
- Conditions
- Lung Neoplasms, Thoracic Neoplasms, Neoplasms by Site, Neoplasms
- Trial name
- MIMIG (NCT02111824)
- Testing
- MIMIG System, Indocyanine Green (ICG)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The Methodist Hospital Research Institute
Pneumothorax, Biopsy, Needle
CT-guided Lung Biopsy Risk Optimization Method
The purpose of this randomized controlled study is to evaluate the extent to which injection of a small amount of fluid in the pleural cavity at the biopsy site may reduce the risk of pneumothoraces, in addition to patient…
- Conditions
- Pneumothorax, Biopsy, Needle, Risk Factors, Radiology, Interventional
- Trial name
- BROM-I (NCT06340178)
- Testing
- Fluid application during ct-guided lung biopsy
- Where
- Switzerland
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Prostate Cancer
Fusion Targeted Biopsy of the Prostate
The objective of the proposed study is to evaluate a new, molecular image directed, three-dimensional (3D) ultrasound guided biopsy system in human patients. The current biopsy uses ultrasound imaging as guidance.
- Trial name
- NCT02013414
- Testing
- 3D ultrasound-guided biopsy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Emory University
Sentinel Lymph Node, Breast Cancer
Sentinel Lymph Node Biopsy in Breast Cancer Surgery Using ICG
This clinical trial is a prospective, multicenter, self-controlled clinical study. In order to meet the requirements of this plan, 130 breast cancer patients need the sentinel lymph node biopsy with novel near-infarred…
- Trial name
- NCT03579979
- Testing
- Methylene Blue, Indocyanine Green
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Chinese Academy of Sciences
Malignancy, Infection
Augmented Reality Headset as Adjunct Display Monitor in AMIGO
The investigators' overarching goal is to investigate whether use of an augmented reality display system (utilized in addition to, not as a replacement to, conventional CT and MRI displays currently available in the procedure…
- Conditions
- Malignancy, Infection, Pain
- Trial name
- NCT03328416
- Testing
- Augmented Reality
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Nasopharyngeal Carcinoma, Image-Guided Biopsy
Detection and Biopsy Guidance of Nasopharyngeal Carcinoma Based on Artificial Intelligence and Endoscopic Images
Due to the occult anatomic location of the nasopharynx and frequent presence of adenoid hyperplasia, the positive rate for nasopharyngeal carcinoma identification during biopsy is low, thus leading to delayed or missed diagnosis…
- Trial name
- NCT05202626
- Testing
- Nasopharyngeal Endoscopy image-guided Biopsy
- Where
- 5 sites in China
- Volunteers
- 100 people
- Sponsor
- Chinese Academy of Sciences
Lung Biopsy
Detection and Prediction of Clinically Significant Pneumothorax After Image-guided Transthoracic Lung Biopsy
Objective: The goal of this study is to evaluate the sensitivity and specificity of the presence of pneumothorax on a 4-hour CXR after image-guided transthoracic lung biopsy (TTLB) for diagnosing subsequent clinically significant…
- Trial name
- NCT06563167
- Testing
- CXR
- Where
- Hong Kong
- Volunteers
- 330 people
- Sponsor
- Chinese University of Hong Kong
Prostate Cancer
Magnetic Resonance Imaging-Transrectal Ultrasound Fusion Image-Guided Prostate Biopsy Following Radical Prostatectomy in Patients With Prostate Cancer
This pilot clinical trial studies magnetic resonance imaging (MRI)-transrectal ultrasound (TRUS) fusion image-guided prostate biopsy following radical prostatectomy in patients with prostate cancer.
- Trial name
- NCT01764347
- Testing
- therapeutic conventional surgery, ultrasound-guided prostate biopsy, magnetic resonance imaging
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Southern California
Image-Guided Biopsy - Carcinoma, Bronchogenic / Diagnosis- Outpatients
CT Scan Guide Percutaneous Biopsy of Lytic Bone Metastases of Lung Cancer : Contribution in Pathology Diagnosis and Molecular Biology
In case of primary lung cancer, bone metastases biopsy can be done in initial diagnosis or follow-up. Nevertheless, any study focus on rentability and biopsy complications of lytic bone lesion for the context of lung cancer.
- Trial name
- stasfa (NCT03386916)
- Testing
- CT scan guide percutaneous biopsy of lytic bone metastases of lung cancer
- Volunteers
- 80 people
- Sponsor
- University Hospital, Grenoble
Lung Neoplasms
Transthoracic Needle Biopsy Using 3D Printed Navigational Template: A Phase I Feasibility Trial
This study evaluates the feasibility of three-dimensional printed template in transthoracic pulmonary nodule biospy. Investigator planned to include 20 patients with lung nodule biopsy schedule to receive template-guided…
- Trial name
- NCT03325907
- Testing
- navigational template
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Prostate Cancer
Biopsy Study Comparing MRI and Ultrasound Soft Image Fusion Guided Biopsies and Gold Standard Prostate Biopsies.
Background: Prostate biopsies are usually performed due to accidentally discovered elevated prostate specific antigen (PSA) and/or abnormal digital rectal examination.
- Trial name
- NCT01455792
- Testing
- Biopsies using image fusion, Gold standard biopsy
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Breast Cancer
Percutaneous Removal and Margin Ablation for Breast Cancer
We hypothesize that radiofrequency ablation after single-insertion image guided vacuum assisted biopsy (IVEB) can be used to achieve negative margins in small unicentric breast cancers (≤1.5 cm).
- Trial name
- NCT00574301
- Testing
- Percutaneous Removal and Margin Ablation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Arkansas
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
A Dose-Image Optimization Trial Evaluating Mannitol and Voluven as Adjuncts for Indocyanine Green
The goal of this clinical trial is to exploring the use of Mannitol 20% as a solvent to prepare ICG solution, combining with Voluven, forming a hybrid small-large molecular weight solvent for protecting ICG in monomer form and…
- Trial name
- ICGMV (NCT06768268)
- Testing
- Voluven-assisted Indocyanine green fluorescence guided sentinel lymph node biopsy for breast cancer, Mannitol (20%)
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Lung Neoplasms, Liver Neoplasms
A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy
Background: Currently, standard procedures for biopsies that are guided by computed tomography (CT) imaging involve CT scans and a computer program to plan and illustrate where the physician will place the needle to obtain the…
- Conditions
- Lung Neoplasms, Liver Neoplasms, Kidney Neoplasms, Cancer
- Trial name
- NCT01218854
- Testing
- Needle angle measurement
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Prostate Neoplasm
PRostate Evaluation for Clinically Important Disease: Sampling Using Image-guidance Or Not?
This evaluates the detection rates of prostate cancer by MRI-targeted prostate biopsy compared to standard 12-core trans-rectal ultrasound guided (TRUS) prostate biopsy.
- Trial name
- PRECISION (NCT02380027)
- Testing
- MRI, MRI-targeted biopsy, TRUS-biopsy
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- University College, London
Barrett's Esophagus
Optical Frequency Domain Imaging (OFDI) Surveillance and Image Guided Biopsy of the Esophagus
The specific aim of this study is to determine the feasibility of marking target pathologic locations identified on Optical Frequency Domain Imaging (OFDI) datasets using superficial cautery marks of the esophagus that are…
- Trial name
- NCT01439633
- Testing
- MGH OFDI marking
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Massachusetts General Hospital
Prostate Cancer, Local Anesthesia
A Prospective Randomized Trial of Two Different Prostate Biopsy Schemes
The main purpose is to compare the detection rate of 20-core versus 12-core prostate biopsy. The secondary objective is to evaluate pain perception using a validated scale to compare the analgesia provided by the two different…
- Conditions
- Prostate Cancer, Local Anesthesia, Prostate-Specific Antigen/Blood, Biopsy/Methods
- Trial name
- NCT02825225
- Testing
- 20 core-biopsy fragments, Base and apex local anesthesia
- Where
- Brazil
- Volunteers
- 750 people
- Sponsor
- University of Nove de Julho
Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma
Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy
This clinical trial studies mechanisms of resistance to 177-lutetium prostate specific membrane antigen (177Lu-PSMA) radioligand therapy using image-guided biopsies in patients with castrate-resistant prostate cancer that had…
- Conditions
- Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IV Prostate Cancer American Joint Committee on Cancer (AJCC) v8, Stage IVA Prostate Cancer AJCC v8
- Trial name
- NCT05398302
- Testing
- Image Guided Biopsy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Jonsson Comprehensive Cancer Center