Clinical trials: Imaging Guided
Rectal Cancer
Magnetic Resonance Imaging (MRI)-Guided Rectal Cancer Preservation Program
The goal of this clinical trial is to learn if the use of MRI-guided irradiation increases the rates of rectal preservation
- Trial name
- NCT07134296
- Testing
- MR-Guided Irradiation
- Volunteers
- 32 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Diabetes
IVI-guided Versus Angiography-guided PCI in Patients With Diabetes Mellitus
Intravascular ultrasound (IVUS) serves as a beneficial instrument during percutaneous coronary intervention (PCI) procedures, affording insight into lesion characteristics and stent implantation.
- Trial name
- IVI-DIABETES (NCT06380868)
- Testing
- Intravascular imaging-guided PCI, Angiography-guided PCI group
- Where
- China
- Volunteers
- 1,332 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Myocardial Infarction, Ventricular Tachycardia
MAgnetic Resonance Imaging-guided implanTation of Cardioverter DEFibrillators
Implantable cardioverter-defibrillators (ICD) are currently recommended for the primary prevention of sudden cardiac death (SCD) in patients with a remote (>6 weeks) myocardial infarction (MI) and a low (≤35%) left ventricular…
- Conditions
- Myocardial Infarction, Ventricular Tachycardia, Ventricular Fibrillation, Sudden Cardiac Death
- Trial name
- SMART-DEF (NCT06269692)
- Testing
- MRI screening, Implantable Loop Recorder, Implantable Cardioverter Defibrillator
- Where
- France
- Volunteers
- 1,812 people
- Sponsor
- Central Hospital, Nancy, France
Unresectable or Metastatic Melanoma
PICSTAT Pilot Study for CD8 PET/CT-Guided Lifileucel Treatment in Advanced Melanoma
This prospective, single-center pilot study is being performed to find out whether Zr-89 crefmirlimab berdoxam "CD8 PET/CT" scans can improve the effectiveness of the tumor-infiltrating lymphocyte (TIL) therapy called lifileucel…
- Trial name
- PICSTAT (NCT07700121)
- Testing
- Resection of PET (high) and PET (low) Tumors, Lifileucel Manufacturing Clinical v Research, Chemotherapy Regimen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Dermatofibrosarcoma Protuberans (DFSP), Skin Squamous Cell Carcinoma
NIFR Image-guided Surgery for Malignant Soft Tissue Tumor With Low-dose SWIG Technique
This research study will evaluate how near-infrared fluorescence (NIRF) imaging with low-dose second window indocyanine green (ICG) can assist in the radical resection and pathologic diagnosis of malignant soft tissue sarcoma…
- Trial name
- NIFR;SWIG (NCT06610071)
- Testing
- ICG administration
- Volunteers
- 592 people
- Sponsor
- The Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Prostate Cancer
Guided Biopsy for Mapping Prostate Cancer
Evaluate the accuracy of HIT guided biopsies for mapping tumor foci with men undergoing prostatectomy.
- Trial name
- HIT (NCT01007214)
- Testing
- Prostatectomy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Roswell Park Cancer Institute
Ischemic Cardiomyopathy
Radial Strain ECHO-Guided Implantation of Cardiac Resynchronization Therapy
The purpose of this study is to evaluate the use of radial strain imaging using speckle tracking analysis to predict the response to CRT in patients with ischemic cardiomyopathy (ICMP) with NYHA functional class 2-4 heart failure…
- Trial name
- RAISE-CRT (NCT01603706)
- Testing
- Echo guided implantation group
- Where
- 9 sites in United States, Israel
- Volunteers
- 172 people
- Sponsor
- Sheba Medical Center
Colorectal Surgery, Ureter
Randomised Controlled Trial of Fluorescent Urography Using Intravenous Methylene Blue Compared to White Light Alone in Left-sided Colorectal Surgery
This study will see if a blue dye (methylene blue) given into a vein, together with a special camera light, helps surgeons find the left ureter (the tube from the kidney to the bladder) faster during left-sided bowel surgery.
- Trial name
- NCT07835932
- Testing
- Intravenous Methylene blue, Fluorescence Imaging Device for Methylene Blue
- Where
- Hong Kong
- Volunteers
- 108 people
- Sponsor
- Chinese University of Hong Kong
Primary Hyperparathyroidism, Thyroid Disease
Optimization and Individualization of Diagnostic Scintigraphy Protocol and Minimally Invasive Radio-guided Parathyroid Surgery
The radio-guided technique offers both help with in-vivo identification and ex-vivo confirmation of parathyroid adenoma. In-vivo accuracy is most important but its results are not satisfactory.
- Conditions
- Primary Hyperparathyroidism, Thyroid Disease, Parathyroid Diseases, Parathyroid Adenoma
- Trial name
- NCT04344886
- Testing
- Conventional (dual-phase) SPECT/CT, Multi-phase SPECT/CT, Conventional minimally-invasive radio-guided parathyroidectomy
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Non-Small Cell Lung Cancer (NSCLC)
MRD and Imaging Guided Adaptive Neoadjuvant Therapy for Resectable NSCLC
Neoadjuvant immunotherapy combined with platinum-based doublet chemotherapy has been established as the standard of care for driver-gene-negative (EGFR/ALK wild-type) stage II-IIIB non-small cell lung cancer (NSCLC), yielding…
- Trial name
- NCT07885709
- Testing
- PD-1 inhibitor, Carboplatin, Nab-paclitaxel
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Ultrasound Imaging of Anatomical Structures
Validity of Experts and ScanNav Anatomy PNB When Identifying Sono-anatomical Structures for Ultrasound-Guided Regional Anaesthesia
This is a multi-centre, prospective, observational study, conducted under the auspices of the University of Oxford to evaluate ultrasound image analysis by human experts and an artificial intelligence device in the context of…
- Trial name
- NCT04983771
- Testing
- Annotate ultrasound scans
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- IntelligentUltrasound Limited
Glioma
Enhanced Detection in Glioma Excision
The purpose of this study is to determine whether use of an ultra-high sensitivity camera with enhanced imaging technology can be used during surgery to detect areas of brain tissue affected by diffuse glioma, a type of brain…
- Trial name
- EDGE (NCT04556929)
- Testing
- Intra-operative imaging of 5-ALA fluorescence using ultra-high sensitivity camera, Intra-operative imaging of 5-ALA fluorescence using in-built operative microscope camera, Biopsies
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- University of Oxford
Ischemic Heart Disease
Registry of Comprehensive Imaging and Physiological Evaluation of Deferred Lesions Based on FFR
1. To compare the risk of atherosclerotic lesion progression and subsequent patient-oriented composite outcomes (all-cause mortality, any MI, or any Ischemia-driven repeat revascularization) between deferred lesions with or…
- Trial name
- IMPACT-FFR (NCT03030495)
- Testing
- Comprehensive physiologic evaluation, Intravascular imaging devices
- Where
- 4 sites in South Korea
- Volunteers
- 1,400 people
- Sponsor
- Samsung Medical Center
Pancreatic Cancer, Pancreatic Adenocarcinoma
Near-infrared Image Guided Surgery in Pancreatic Adenocarcinoma
There is a need for better visualization of resection margins and detection of small tumor deposits during surgery for pancreatic cancer.
- Trial name
- PENGUIN (NCT02743975)
- Testing
- Bevacizumab-800CW
- Where
- 3 sites in Netherlands
- Volunteers
- 10 people
- Sponsor
- University Medical Center Groningen
Head and Neck Neoplasms
The Translational Research Image-Guided Operating Room (TRIGORA): Intraoperative 3D Imaging for Head & Neck Surgical Patients
Head and neck cancer surgery presents the challenge of tumour resection in close proximity to critical structures such as the carotid arteries and optic nerves.
- Trial name
- TRIGORA (NCT03345719)
- Testing
- 3D Cone-Beam Imaging
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University Health Network, Toronto
Cervical Cancer
Magnetic Resonance Imaging (MRI) Brachytherapy Applicator Study
The goal of this clinical research study is to learn if computed tomography (CT) and magnetic resonance imaging (MRI) images can better help to plan internal radiation treatment.
- Trial name
- NCT01706705
- Testing
- Intracavitary Applicator Placement, Computed Tomography (CT), Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer
MRI-guided Focal Laser Ablation
Magnetic resonance imaging-guided focal laser ablation of prostate cancer.
- Trial name
- Unicorn (NCT04379362)
- Testing
- Focal laser ablation
- Where
- Netherlands
- Volunteers
- 53 people
- Sponsor
- Radboud University Medical Center
Pancreas Adenocarcinoma
NIR-Fluorescence Guided Surgical Resection of Neoadjuvant Treated Localized Pancreatic Cancer Using SGM-101
Pancreatic carcinoma has a dismal prognosis at time of diagnosis, due to late onset of clinical symptoms, patients present with advance disease.
- Trial name
- FLUOPANC-II (NCT05984810)
- Testing
- Fluorescence-guided surgery using CEA-targeted fluorophore SGM-101
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Uterine Cervical Neoplasms
Exploratory Study on NIRFI Technology Combined with ICG Guided Cervical Cancer Lymph Node Metastasis
The goal of this exploratory study is to exploring the lymph node metastasis, tumor margin, blood vessels, ureters, and nerve imaging in cervical cancer surgery using near-infrared fluorescence imaging technology combined with…
- Trial name
- NCT06840418
- Testing
- Indocyanine green (ICG) injection for intraoperative lymph node imaging
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Obstetrics & Gynecology Hospital of Fudan University
Anesthesia, Local
PACMAN Ultrasound Recording Data Collection
Study to collect videos of ultrasound recordings during peripheral nerve block procedures.
- Trial name
- NCT03368976
- Where
- 8 sites in United States
- Volunteers
- 767 people
- Sponsor
- Avanos Medical