Clinical trials: Immediate Effect
Dermatitis, Atopic
Clinical Effect, Safety and Tolerability of GSK1070806 in Atopic Dermatitis
This study will evaluate efficacy and safety of GSK1070806 in moderate to severe atopic dermatitis (AtD) participants.
- Trial name
- NCT04975438
- Testing
- GSK1070806
- Where
- 11 sites in United States, Canada
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
Parkinson's Disease With End of Dose Wearing Off
Effects of Carbidopa/Levodopa/Entacapone on Motor Function and Quality of Life in Patients With Parkinson's Disease
To assess motor function and quality of life (QoL) in Parkinson's disease (PD) subjects with end-of-dose wearing off, comparing immediate and delayed switch to carbidopa/levodopa and entacapone.
- Trial name
- NCT00219284
- Testing
- Carbidopa/levodopa/entacapone
- Where
- 42 sites in United States, Puerto Rico
- Volunteers
- 359 people
- Sponsor
- Novartis Pharmaceuticals
Lateral Elbow Tendinopathy, Elbow Pain
Isometric Intervention for Lateral Elbow Tendinopathy
This study will be looking at people with lateral elbow tendinopathy (elbow pain). The goal is to determine if a one-time isometric intervention will positively change the level of pain and strength as compared to baseline…
- Conditions
- Lateral Elbow Tendinopathy, Elbow Pain, Elbows Tendonitis, Elbow Sprain
- Trial name
- NCT03756155
- Testing
- isometric intervention
- Where
- United States
- Sponsor
- University of Minnesota
Asthma
Evaluation of the Effect of Web-designed Training Developed for Asthma Patients
The study is an experimental study with pre-test-post-test control group in order to determine the effect of web-designed training developed for asthma patients on drug compliance, asthma control, and fatigue
- Trial name
- NCT04607681
- Testing
- EDUCATION
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Asthma
Examining the Effects of a Remote Pulmonary Rehabilitation Program in the Severe Asthma Population.
This is a randomized control trial evaluating the effect of a novel mobile application-delivered pulmonary rehabilitation program in adult severe asthma patients.
- Trial name
- STAPLE (NCT06150300)
- Testing
- Pulmonary rehab program
- Volunteers
- 34 people
- Sponsor
- University of Saskatchewan
Asthma
Effect of Clopidogrel on Allergen Challenge in Asthma
In asthma, breathing in an allergen, such as house dust mite induces inflammation in the airways. This process appears to involve an interaction between two different sorts of blood cells, platelets and white blood cells via a…
- Trial name
- NCT01955512
- Testing
- Clopidogrel
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University of Southampton
Asthma
Investigate the Effect of the CREON2000A on Asthma Control in Children With Mild to Moderate Persistent Asthma
This is a pivotal, 12-month, randomized, sham controlled, parallel group, multicenter, double blind study with an allocation ratio of 1:1.
- Trial name
- CREON2000A (NCT02715375)
- Testing
- CREON2000A
- Where
- 8 sites in United States
- Volunteers
- 83 people
- Sponsor
- General Innovations and Goods, Inc.
Childhood Asthma, Passive Smoke Exposure
The Invisible Trigger: A Quasi-Experimental Study on the Effect of Passive Smoke Exposure and Counselling Intervention in Childhood Asthma
This study evaluates the effect of passive smoke exposure on childhood asthma and the role of structured counseling in reducing SHS exposure and improving asthma control.
- Trial name
- Asthma (NCT07069192)
- Testing
- Counselling
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Foundation University Islamabad
Asthma
Effects of Balloon-blowing Exercises in 90/90 Bridge Position With a Ball on Pulmonary Function Among Asthmatic Patients
In asthma, the airways in the respiratory system can experience inflammation and constriction, causing increased difficulty in expelling air during exhalation.
- Trial name
- NCT06660537
- Testing
- Balloon-blowing exercises in 90/90 bridge position with a ball., Buteyko breathing exercises management
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- Foundation University Islamabad
Asthma
Study to Assess the Effect of the NEXThaler® Device (DPI - Dry Powder Inhaler) on the Central and Peripheral Airway Dimensions in Asthmatic Patients
The objective of this study is to evaluate the effect of the combination of formoterol and beclometasone dipropionate in a dry powder inhaler (NEXThaler®) on central and peripheral airway dimensions in asthmatic patients.
- Trial name
- NCT01650441
- Testing
- Beclomethasone dipropionate 100 µg + formoterol fumarate 6 µg, CT thorax
- Where
- Belgium
- Volunteers
- 31 people
- Sponsor
- University Hospital, Antwerp
Asthma
Assessment Of The Effects Of Short and Long Term Use Of CPAP
We hypothesize that the nocturnal use of continuous positive airway pressure in adults and children with asthma will decrease airway reactivity.
- Trial name
- NCT00592631
- Testing
- CPAP-Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Indiana University
Asthma, COPD
Effect of Spacer Use on Exacerbation Risk in High-Risk Older Adults With Chronic Airway Diseases Receiving Triple Therapy
This study evaluates whether adding a spacer device to triple inhaled therapy (ICS/LABA/LAMA via pMDI) can reduce acute exacerbations in elderly patients (≥65 years) with stable chronic airway diseases (COPD or asthma) who are…
- Trial name
- NCT07030881
- Testing
- pMDI Triple Inhaler and Spacer, pMDI Triple Inhaler Only
- Where
- 9 sites in China
- Volunteers
- 380 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Asthma
Study to Evaluate Efficacy & Safety of Tralokinumab in Subjects With Asthma Inadequately Controlled on Corticosteroids
A Multicentre, Randomized, Double-blind, Parallel Group, Placebo Controlled, 12-Week, Phase 2 Study to Evaluate the Effect of Tralokinumab on Airway Inflammation in Adults with Asthma Inadequately Controlled on Inhaled…
- Trial name
- MESOS (NCT02449473)
- Testing
- Tralokinumab
- Where
- 15 sites in Canada, Denmark and 1 more
- Volunteers
- 79 people
- Sponsor
- AstraZeneca
Oral Biofilm, Periodontitis
Methodology Antiseptic Application, Influence on Oral Biofilm.
The study has the objective to compare two different methodology of application the antiseptic on the oral biofilm will be formed during 48h in situ on a specific device.
- Conditions
- Oral Biofilm, Periodontitis, Gingivitis
- Trial name
- NCT02267239
- Testing
- essential oils, immersion, Chlorhexidine, immersion, essential oils, mouthwash
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Asthma
Study of ARO-RAGE in Healthy Subjects and Patients With Inflammatory Lung Disease
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of ARO-RAGE in normal healthy volunteers (NHVs) and in participants with inflammatory lung disease (asthma).
- Trial name
- NCT05276570
- Testing
- ARO-RAGE
- Where
- 8 sites in Australia, New Zealand and 3 more
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Arrowhead Pharmaceuticals
Asthma
Effect of Omalizumab in Patients With Severe Persistent Non-atopic Uncontrolled Asthma
This study will assess the change in the expression of FcεRI receptors of blood basophils and dendritic cells after 16 weeks of treatment with omalizumab as compared with placebo, in adult patients with non-atopic severe…
- Trial name
- NATAIR (NCT01007149)
- Testing
- omalizumab
- Where
- 10 sites in France
- Volunteers
- 79 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
Analysis of Exhaled Breath by Biosensors in Adults With Asthma
The aim of this study is to investigate the pattern of organic volatile compounds (VOCs) in the exhaled breath detected by biosensors in adults with persistent mild asthma.
- Trial name
- NCT00819676
- Testing
- analysis of exhaled breath by biosensors, measurement of exhaled nitric oxide
- Where
- Italy
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Atopic Dermatitis
Clinical Trial to Evaluate the Effect of a Probiotic Mixture in the Treatment of Atopic Dermatitis in Children
A prospective case-control multicentric pilot study of 12 weeks duration to evaluate the effect of a probiotic mixture in the treatment of atopic dermatitis in children from 0 to 3 years old, by measuring the severity of the…
- Trial name
- NCT05443490
- Testing
- Probiotic mixture with three bacterial strains with maltodextrin as a carrier.
- Where
- 3 sites in Bolivia, Costa Rica and 1 more
- Volunteers
- 4 people
- Sponsor
- Bionou Research, S.L.
Asthma, Status Asthmaticus
Study Evaluating the Safety and Effects of MN-221 in Subjects Experiencing an Acute Exacerbation of Asthma
The objective of this clinical study is to examine the safety and effectiveness of intravenous MN-221 compared to placebo when administered as an adjunct to standard therapy in subjects experiencing an acute exacerbation of…
- Trial name
- NCT00683449
- Testing
- Dose Group 1, Dose Group 2, Dose Group 3
- Where
- 9 sites in United States
- Volunteers
- 29 people
- Sponsor
- MediciNova
Asthma
Effect of in Vitro Blocking the Common Beta Chain on Cell Viability in Asthma
This study examines in vitro blockade of signaling through the β-chain, on viability, activation and differentiation of eosinophils and their progenitors collected in sputum, blood and bone marrow samples pre and post-allergen…
- Trial name
- NCT01759849
- Testing
- Allergen
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation