Clinical trials: Immobilization
Finger Injuries
Treatment of Proximal Interphalangeal Joint Injuries. Clinical Efficiency of Syndactyly Treatment and Digital Compression
Proximal interphalangeal joint injuries of the fingers may be treated in various ways and no treatment has been shown to be superior.
- Trial name
- NCT02548260
- Testing
- Syndactyly without compression, Syndactyly with compression, Rigid splint without compression
- Where
- Switzerland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Motion Analysis, Biomechanical Parameters
The Impact of Shoulder Immobilization by Orthoses on Human Joint Biomechanics and Inter-joint Coordination
Shoulder joint orthoses are commonly used for patients with shoulder disorders to stabilize and protect shoulder joint after injury or surgery.
- Trial name
- Biomechanics (NCT07659054)
- Testing
- Shoulder immobilization by sling
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Muscle Protein Synthesis, Endotoxemia
Whey vs Casein to Combat Post-inflammatory Protein and Muscle Waste in Acute Disease
This study compares three different protein supplements (casein, whey and leucine-enriched whey) and their effect on post-inflammatory muscle waste in a model of acute disease.
- Conditions
- Muscle Protein Synthesis, Endotoxemia, Nutrition, Milk Protein
- Trial name
- NCT03319550
- Testing
- Casein, Whey, Leucine-enriched whey
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Muscle Atrophy, Disuse Atrophy (Muscle) of Lower Leg
The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation
It is well known that periods of weight training lead to increases in skeletal muscle size and strength. In contrast, periods of inactivity such as bed rest or immobilization result in losses of skeletal muscle size and strength.
- Trial name
- HYPAT (NCT03046095)
- Testing
- Unilateral Resistance Exercise, Immobilization
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- McMaster University
Muscle Loss
Brain Stimulation During Arm Immobilisation
The research project explores how non-invasive brain stimulation can be used to detect and ameliorate loss of muscle strength after inactivity.
- Trial name
- ImmobiStim (NCT04130581)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Prostate Cancer
External Immobilization Compared to Limited Immobilization Using a Novel Real-time Localization System of the Prostate
This prospective study at MAMC evaluates the utility of a rigid pelvic external immobilization compared to limited immobilization using a novel real-time localization system of the prostate.
- Trial name
- NCT01588938
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research Acquisition Activity
Cervical Spine
Measurements of Angulation of the C-spine
This is a prospective study aiming to assess the shape of the neck in adults. In addition the study will look at the shape of the neck in a spinal collar and the comfort while wearing a spinal collar.
- Trial name
- NCT03958149
- Testing
- spinal collar
- Where
- 2 sites in United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Snake Bites, Snakebite
Analysis of the Efficacy of Pressure Pad vs Pressure Bandage Immobilisation for Snake Bite First Aid in Healthy Volunteers.
Snake bite affects thousands of Australians every year, but few die as a result due to high quality first aid and timely medical care.
- Conditions
- Snake Bites, Snakebite, Snake Envenomation, Snake Bite
- Trial name
- NCT07261982
- Testing
- Pressure bandage immobilisation first aid, Pressure pad first aid, Control - no first aid
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Townsville University Hospital
Healthy
Forearm Immobilization, Metabolic Health, and Muscle Loss
The present study will investigate the impact of altered substrate availability on muscle atrophy, insulin sensitivity and muscle protein synthesis following short-term forearm immobilization
- Trial name
- NCT03866512
- Testing
- Forearm immobilization
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Automobile Driving With an Aircast Walker, Automobile Driving With a Walking Cast
Effects of Right Lower Limb Orthopedic Immobilization on Braking Function
Research on the implications of orthopedic injury and surgery on automobile driving ability has been limited. Only a handful of orthopedic issues have been studied to date, especially the safe postoperative resumption of driving.
- Trial name
- NCT01171287
- Testing
- Driving with an Aircast Walker, Driving with a walking cast, Driving with a running shoe
- Where
- 2 sites in Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Transcranial Direct Current Stimulation
Effects of Transcranial Direct Current Stimulation After Short-term Immobilization on Motor Learning and Hand Function in Healthy Young Adults
The purpose of the study is to investigate the effects of short-term braking on the motor learning and fine motor skills of healthy adults, and to analyze whether transcranial direct current stimulation can alleviate the effects…
- Trial name
- NCT07089056
- Testing
- transcranial direct current stimulation, immobilization
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Muscle Disuse Atrophy, Nutrition, Healthy
Effect of a Natural Source Supplementation on Muscle Mass
Periods of muscle disuse are commonly experienced in young and elderly individuals as a result of short-term hospitalization or leg casting after injury.
- Trial name
- NCT05369026
- Testing
- Single leg immobilization
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- McMaster University
Optic Nerve Sheath Diameter, Point of Care Ultrasound
Effect of Cervical Immobilization on Optic Nerve Sheath Diameter
Effect of Cervical Immobilization on Optic Nerve Sheath Diameter
- Trial name
- NCT04507620
- Testing
- cervical neck collar
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanta University
Injury of Extensor Tendon of Hand (Disorder)
Functional Recovery Measurement : Comparing Early Active Mobilization Versus Immobilization After Extensor Tendon Repair in Zones IV to VIII
Functional recovery measurement : Comparing early active mobilization versus immobilization after extensor tendon repair in zones IV to VIII.
- Trial name
- NCT04221113
- Testing
- physiotherapy
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
Abduction Brace Versus Antirotation Sling for Immobilization Following Reverse Shoulder Arthroplasty and Rotator Cuff Repair
To compare the functional and anatomical outcomes, and patient satisfaction and compliance between two different postoperative immobilization methods - abduction shoulder brace versus simple arm sling - following 2 common…
- Trial name
- NCT03488433
- Testing
- Abduction brace, Antirotation sling
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Muscle Disuse Atrophy
Can Supplemental Leucine Offset Disuse-induced Muscle Atrophy?
Ageing is associated with a gradual decline in muscle mass that is detrimental to both physical function and metabolic health, increasing the risk of morbidity and mortality.
- Trial name
- LEU-DIMA (NCT03762278)
- Testing
- Leucine
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Muscle Weakness
Mitigating Neural Hypoexcitability and Weakness During Disuse in Women
Clinical trial The goal of this clinical trial is to learn how muscle weakness and atrophy develop during short periods of arm immobilization and whether a type of exercise called cross-education can help reduce these effects in…
- Trial name
- MiND (NCT07166198)
- Testing
- Wrist immobilization, Resistance training, Resistance training rehabilitation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Atrophy, Muscular, Atrophy, Disuse
Blood Flow Restricted Electrical Stimulation During Immobilisation
Following injury or surgery to a limb, it is often immobilised to allow tissue healing. Short periods of disuse cause loss of muscle size and strength and impaired mechanical properties of tendons, which leads to reduced…
- Trial name
- NCT05093985
- Testing
- Neuromuscular electrical stimulation with blood flow restriction
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Pediatrics, Immobilization
Immobilization During Peripheral Venous Catheter Placement
Aim: To determine the most effective type of upper limb immobilization in the cannulation of a peripheral venous line in the pediatric emergency department.
- Trial name
- NCT07182994
- Testing
- Elbow joint immobilization, Arm restraint without elbow immobilization
- Where
- Spain
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Mitochondrial Energetics, Dietary Nitrate
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men
Diminished use of skeletal muscle, such as occurs with many chronic diseases (e.g., heart failure or cancer cachexia), denervation, bedrest, immobilization (e.g., limb casting or bracing), etc., is a common clinical condition…
- Conditions
- Mitochondrial Energetics, Dietary Nitrate, Disuse Atrophy (Muscle) of Lower Leg
- Trial name
- NCT07161973
- Testing
- Beetroot Juice - Active
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Indiana University