Clinical trials: Immune Health
Diabetes Mellitus, Type 1
Strengths-Based Behavioral mHealth App for Parents of Adolescents With Type 1 Diabetes-Pilot Study
Type 1 diabetes (T1D) management is particularly challenging during adolescence as responsibility for management begins to shift from parents to youth, and positive family teamwork is critical to achieving optimal diabetes…
- Trial name
- T1DoingWell (NCT02877680)
- Testing
- T1Doing Well
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Baylor College of Medicine
Rheumatoid Arthritis
REU-stop - Effect of Intensive Smoking Cessation Intervention on Smoking Cessation and Disease Activity in Patients With Rheumatoid Arthritis.
This study aims to test the effect of an intensive smoking cessation intervention (motivational counseling combined with nicotine replacement) on smoking cessation and disease activity in patients with Rheumatoid Arthritis (RA).
- Trial name
- NCT02901886
- Testing
- Intensive smoking cessation intervention
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 150 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Bronchial Asthma, Adherence, Medication
Efficacy of a Phone Application on Treatment Adherence in Asthmatic Patients in Upper Egypt
asthma adherence is mandatory for disease control
- Trial name
- NCT06233123
- Testing
- the Medisafe android application (https://www.medisafe.com).
- Volunteers
- 180 people
- Sponsor
- Assiut University
Asthma
Does Improving Insulation and Heating Improve Health?
The Housing, Heating and Health Study has enrolled 409 households with ineffective heaters, who have a child with asthma between 6 and 12 years.
- Trial name
- NCT00489762
- Testing
- Installation of an energy efficient heater
- Where
- New Zealand
- Volunteers
- 409 people
- Sponsor
- University of Otago
Asthma
Asthma and Health Literacy in Newcomer Communities in the Greater Vancouver Area
In this study, the investigators aim to develop and test the effectiveness of culturally appropriate asthma videos and other educational materials based on knowledge from this study and the investigators' previous studies.
- Trial name
- NCT01474928
- Testing
- patient role played community video, both videos group, Pamphlet group
- Where
- 2 sites in Canada
- Volunteers
- 92 people
- Sponsor
- University of British Columbia
Chronic Disease, Asthma
Feasibility of Ripple Health Smart Pill Caps in Clinical Settings
The purpose of this research is to determine whether Ripple Health Smart Medicine Bottle Caps can allow for better interface medication administration than traditional pill bottles.
- Trial name
- NCT05192928
- Testing
- Ripple Health Smart Pill Cap
- Where
- 4 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Manan Shukla
Arthritis
Evaluation of the Active Living Every Day Exercise Program for People With Arthritis
The primary goal of this study is to assess the effectiveness and feasibility of the Active Living Every Day Physical Activity Program (ALED) for people with arthritis.
- Trial name
- NCT00146367
- Testing
- Active Living Every Day
- Volunteers
- 355 people
- Sponsor
- Centers for Disease Control and Prevention
Multiple Myeloma (MM), Hematologic Neoplasm
Factors Associated With Health-related Quality of Life and Social Participation of Patients With Multiple Myeloma and Their Caregivers
Individuals with multiple myeloma (MM) are vulnerable because of the effects of systemic organ damage and the side effects of treatment.
- Trial name
- MMYLIFE (NCT07014865)
- Where
- Italy
- Volunteers
- 190 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Substance-Related Disorders, Mental Disorder
Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa
Poor engagement in care contributes to HIV- and TB-related morbidity and mortality in South Africa (SA). Community health workers (CHWs) are frontline lay health workers who work to re-engage patients who are lost to follow-up…
- Conditions
- Substance-Related Disorders, Mental Disorder, Social Stigma, Depression
- Trial name
- Siyakhana (NCT05282173)
- Testing
- Siyakhana CHW Training
- Where
- South Africa
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Multiple Sclerosis
Fatigue Management Programs for People With MS
This is a multi-site randomized clinical trial comparing 3 modes of delivering the Managing Fatigue course for reducing fatigue in individuals with multiple sclerosis (MS).
- Trial name
- NCT03550170
- Testing
- Teleconference, Internet, 1-to-1, in-person or videoconference
- Where
- 3 sites in United States
- Volunteers
- 590 people
- Sponsor
- Case Western Reserve University
Multiple Myeloma, Relapsed Hematologic Malignancy
PRO and Wearable Data Insights From Individuals With R/R Multiple Myeloma
This study will evaluate the feasibility of a digital health coaching program for adults with relapsed or refractory multiple myeloma (R/R MM). One hundred adults with R/R MM will be enrolled at The University of Washington.
- Trial name
- NCT05956457
- Testing
- Digital Health Coaching Program, Fitbit
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Pack Health
Sexually Transmitted Diseases, Pregnancy
Internet-Based Sexual Health Education for Middle School Native American Youth
This study will evaluate the effect of an American Indian/Alaska Native (AI/AN) adaptation of the It's Your Game…Keep It Real (IYG) intervention, relative to a comparison condition on sexual behavior outcomes and psychosocial…
- Conditions
- Sexually Transmitted Diseases, Pregnancy, HIV Infections
- Trial name
- IYG-AI/AN (NCT01303575)
- Testing
- HIV, STI and Pregnancy Prevention Curriculum, Control Curricula
- Where
- 4 sites in United States
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pneumonia, Pulmonary Fibrosis
Pulmonary Rehabilitation in Non-chronic Obstructive Pulmonary Disease Patients.
To determine the effect of pulmonary rehabilitation on pulmonary function in non-chronic obstructive pulmonary disease patients.To determine the effect of pulmonary rehabilitation on health related quality of life in non-chronic…
- Conditions
- Pneumonia, Pulmonary Fibrosis, Tuberculosis, Bronchiectasis
- Trial name
- NCT05174741
- Testing
- Conventional Chest Physiotherapy, Aerobic training Group
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Hiv, AIDS
ALHIV Smartphone Game Study
This is a cluster-randomized controlled trial that aims to conduct comprehensive feasibility testing of a smartphone game in a sample of 120 adolescents living with HIV (ALHIV) ages 15-21 in Kisumu, Kenya, to determine whether…
- Conditions
- Hiv, AIDS, Adolescent Behavior, Treatment Compliance
- Trial name
- NCT06913660
- Testing
- MyGoals, Standard of care
- Where
- Kenya
- Volunteers
- 120 people
- Sponsor
- Emory University
HIV Infections, Tuberculosis
Digital Health Promotion in Iringa, Tanzania
Increased health education has the potential to facilitate better use of health care services and to promote early treatment, thus it can strengthen the health care system, and ultimately reduce morbidity and mortality.
- Conditions
- HIV Infections, Tuberculosis, Cysticercosis, Tapeworm Pork
- Trial name
- NCT03808597
- Testing
- Digital health promotion intervention
- Where
- 6 sites in Tanzania
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Oslo
HIV/AIDS, STI
MAKASI Intervention for African and Caribbean Migrants' Empowerment in Sexual Health in Paris Greater Area
Background. Immigrants from Sub-Saharan Africa are the second group most affected by HIV in France. Part of these HIV infections occurred after arrival in France, in relation to social hardships.
- Trial name
- MAKASI (NCT04468724)
- Testing
- MAKASI
- Where
- France
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Asthma, Wheezing
Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation
In a randomized clinical trial (RCT) published in JAMA, the investigators have provided evidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates the effects of maternal smoking during pregnancy on…
- Conditions
- Asthma, Wheezing, In Utero Nicotine, Pulmonary Function
- Trial name
- VCSIP-ECHO (NCT03206710)
- Testing
- No current intervention
- Where
- 2 sites in United States
- Volunteers
- 395 people
- Sponsor
- Oregon Health and Science University
Osteonecrosis, Acute Lymphoblastic Leukemia
Osteonecrosis in Children With Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia is the most common form of childhood cancer with current treatment survival rates approaching 80%. Improved outcomes show an increased number of survivors at risk for long-term treatment related side…
- Trial name
- NCT01104324
- Where
- 10 sites in Canada
- Volunteers
- 130 people
- Sponsor
- Halton, Jacqueline, M.D.
Anaphylaxis, Mastocytosis
Analysis of the Role of IgE Proteoforms in Health and Disease
The goal of this observational study is to evaluate the role of IgE proteoforms in healthy volunteers and in patients with type I allergy, patients with chronic spontaneous urticaria, patients with a recent history of…
- Conditions
- Anaphylaxis, Mastocytosis, X-linked Agammaglobulinaemia, Venom Allergy
- Trial name
- IgE-PhD (NCT07328178)
- Testing
- Blood sample collection
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Asthma
Effectiveness of an Integrated Care Program on Asthma Control and Inhaled Corticosteroids Adherence
The investigators propose to implement and evaluate an integrated care program for enhancing the care of patients with asthma in a region of Quebec province, Canada.
- Trial name
- RESPIRE (NCT02093013)
- Testing
- Integrated care program
- Where
- Canada
- Volunteers
- 349 people
- Sponsor
- Laval University
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