Clinical trials: Immune System Function
Type 1 Diabetes
Vascular Function in Adolescent, Diabetic Children
The objectives of this investigator initiated study are to: 1. Determine if and when vascular abnormalities occur during early adolescence 2. Determine if poor diabetic control is related to vascular abnormalities.
- Trial name
- NCT00348179
- Testing
- Measurement of vascular function per SphymgnoCor equipment
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Healthy Volunteers, Immune System
Assessment of the Immunomodulatory Potential of Spirulina Blue Protein Capsule on Immunomodulation in Healthy Volunteers
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the safety and immunomodulatory effects of Spirulina Blue Protein capsules in healthy adults.
- Trial name
- NCT07733362
- Testing
- Spirulina capsules
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Phayao
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Retinal Function in Diabetic Patients Without Retinopathy
The primary purpose was to assess, in diabetic patients without diabetic retinopathy and control subjects, color vision, contrast sensitivity, electroretinography, and flicker-induced vasodilatation using the Dynamic Vessel…
- Trial name
- NEURODIAB (NCT00839150)
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Constipation
A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation
Constipation is common in the general population, especially in women and in the elderly. Hard stool is a complaint often associated with constipation, which suggests that stool softening would provide a major benefit in the…
- Trial name
- NCT02073006
- Testing
- Natural Fibre Supplement
- Where
- Ireland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials
Asthma, Pneumonia
The Influence of Medical Clowns on the Performance of Pulmonary Function Tests Among Preschooler Children
Medical clowns are known to assist in relaxing children and allowing better cooperation during performance of medical procedures.
- Trial name
- clowns (NCT02708225)
- Testing
- medical clown
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Multiple Sclerosis
Restoration of Walking in Multiple Sclerosis Using Treadmill Training.
The primary purpose of this study is to collect preliminary and pilot data to begin to determine whether the use of body weight support treadmill therapy (BWSTT) with and without driven-gait-orthotics (DGO), results in improved…
- Trial name
- NCT00156676
- Testing
- Body-weight supported treadmill, Lokomat
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
HIV Infections, HIV Seronegativity
A Study of Immune System Activity in Healthy Adults
The purpose of this study is to compare immune system activity in young people and older people who do not have HIV. This information will be compared to that of HIV patients in another study.
- Trial name
- NCT00014053
- Where
- 9 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Allergy, Gastrointestinal Function
Can Supplementation With Lactobacillus Reuteri and Omega-3 Fatty Acids During Pregnancy and Lactation Reduce the Risk of Allergic Disease in Infancy?
The incidence of allergic disease has increased worldwide during the last decades. Initially, a lot of effort has been put in elucidating which of the known risk factors commonly associated to the development of allergic disease…
- Trial name
- PROOM-3 (NCT01542970)
- Testing
- Omega-3 fatty acids, Refined coconut and peanut oil without L. reuteri, L. reuteri
- Where
- Sweden
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- Ostergotland County Council, Sweden
Bronchial Asthma, Pulmonary Healthy Controls
Evaluation of Novel Lung Function Parameters in Patients With Bronchial Asthma
Current guideline-based criteria defining bronchial asthma do not always meet the challenges set by the complex pathophysiology of the disease.
- Trial name
- NCT03820427
- Testing
- impulse oscillometry, multiple breath washout test, body plethysmography
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Multiple Sclerosis
Improving Hand Movement and Coordination in People With Multiple Sclerosis Using Transcranial Magnetic Stimulation (TMS) and Muscle Electrostimulation (FES) To Support Manual Dexterity and Daily Function
The goal of this interventional study is to test whether combining transcranial magnetic stimulation (TMS) with functional electrical stimulation (FES) can improve hand and upper limb function in adults with Multiple Sclerosis…
- Trial name
- MANTRAStim (NCT07098273)
- Testing
- TMS and FES- based rehabilitation, FES-based rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
HIV Infections
The Use of Bacteriophage Phi X174 to Assess the Immune Competence of HIV-Infected Patients In Vivo
The objective of this study is to evaluate the safety and utility of bacteriophage phi X174 immunization as a tool to assess the immune competence of HIV-infected patients at different stages of disease in vivo, and to assess the…
- Trial name
- NCT00001540
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Multiple Sclerosis
Study of Social Cognition by Morphological and Functional Imaging in Multiple Sclerosis Patients
In recent years, studies have brought knowledge of the difficulties of social cognition in Multiple Sclerosis (MS). The brain tissue alteration at the origin of these difficulties in social cognition mechanisms remain poorly…
- Trial name
- SOCOG-MS (NCT02290587)
- Testing
- Brain MRI - Clinical and cognitive evaluation, MRI
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Asthma-COPD Overlap Syndrome
This Study Include Asthma Chronic Obstructive Pulmonary Disease (COPD) Overlap Patients.Patients Were Vitamin D Deficient.Age Range 40-70 Years, Smokers.Patients Were Advised to Take Either Placebo or Vitamin D3.Lung Functions and Exercise Tolerance Were Assessed at Baseline and at 26th Weeks.
Vitamin D3 supplementation doen not change lung functions and exercise tolerance in vitamin D3 deficient ACO patient was the null hypothesis of the research.
- Trial name
- NCT03880734
- Testing
- Cholecalciferol
- Where
- Bangladesh
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
HIV Dementia
Exploring Racial Disparities in Sleep Health and Neurocognitive Function
Despite longer life expectancies due to combination antiretroviral therapy (cART), the prevalence of HIV-associated neurocognitive disorders (HAND) persists thus affecting 52% of the HIV population.
- Trial name
- NCT04015830
- Testing
- electroencephalography (EEG) and event related potentials (ERP)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Pediatric ALL
Assessing Neurophysiological and Cognitive Function in School Children
This trial will investigate the feasibility of implementing our novel assessment battery in a neurodiverse pediatric population.
- Trial name
- WIS (NCT06209528)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Life University
Multiple Sclerosis
Telerehabilitation Based Motor Imagery and Action Observation Training in Multiple Sclerosis
This study aims to investigate the effects of the treatment combination consisting of motor imagery and action observation therapy on balance, functional mobility, lower extremity muscle strength, fatigue and quality of life.
- Trial name
- NCT06295601
- Testing
- Traditional rehabilitation, Action observation therapy and motor imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Inonu University
Exercise Induced Asthma
Kt and Myofascial Release in Exc Asthma
Purpose of this study was to compare between the effects of kinesio tap and myofascial release of respiratory muscles on exercise induced asthma
- Trial name
- NCT05703334
- Testing
- Kinesio tap
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sensitivity
Effects of Acute Intermittent Hypoxia on Sensory Function in Healthy Adults
Exposure to acute intermittent hypoxia (AIH) can facilitate of motor output but no studies of sensory effects has been reported.
- Trial name
- SensoryFLO (NCT03283072)
- Testing
- Intervention 1, Intervention 2, Intervention 3
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Multiple Sclerosis
The Effect of Dual Task On Upper Extremity Functions In Multiple Sclerosis Patients
The primary aim of this study was to investigate the effect of dual tasking on upper extremity functions in individuals with multiple sclerosis (MS) and compare with healthy controls.
- Trial name
- NCT06270342
- Testing
- dual task assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Immune Thrombocytopenia, Thrombocytopathy
Assesment of the Functional Activity of Platelets for the Differential Diagnosis of Thrombocytopathies
The purpose of this study is to develop a highly sensitive method for assessing the functional activity of platelets for use in the differential diagnosis of thrombocytopenia and platelet defects.
- Conditions
- Immune Thrombocytopenia, Thrombocytopathy, Acute Leukemia, Hemorrhagic Disorders
- Trial name
- NCT05654766
- Testing
- Flow cytometry, Platelet aggregation and plasma coagulation
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus