Clinical trials: Immune System Function
Multiple Sclerosis, Mobility Limitation
Innovative Approaches to Enhance Balance and Neuroplasticity in Multiple Sclerosis
This study will evaluate the effects of combining balance training with electrical stimulation techniques in individuals with Multiple Sclerosis (MS).
- Conditions
- Multiple Sclerosis, Mobility Limitation, Balance; Distorted, Gait
- Trial name
- NCT07174973
- Testing
- Balance training with FES, Balance training wiith combined neuromodulation (TSCS+FES), Balance training only
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University Health Network, Toronto
Rheumatoid Arthritis
Tai Chi for Patients With Rheumatoid Arthritis
The purpose of this study was to study the impact of Tai Chi group exercise on physical function, health and disease activity of patients with RA, and to examine the patients' experience and perception of Tai Chi.
- Trial name
- NCT00522054
- Testing
- Physical exercise
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Diakonhjemmet Hospital
Sensitivity
Effects of Acute Intermittent Hypoxia on Sensory Function in Healthy Adults
Exposure to acute intermittent hypoxia (AIH) can facilitate of motor output but no studies of sensory effects has been reported.
- Trial name
- SensoryFLO (NCT03283072)
- Testing
- Intervention 1, Intervention 2, Intervention 3
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Immune Thrombocytopenia
The Association Between Platelet Reactivity and Bleeding Risk in Adult ITP
It seems reasonable to assume that patients who present significant bleeding symptoms may have different quality of platelets than those without bleeding.
- Trial name
- NCT03377439
- Testing
- Platelet function tests
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shandong University
Hodgkin Disease, Lymphoma, Non-Hodgkin
Functional Assessment of Cancer Therapy - Bone Marrow Transplant
Functional Assessment of Cancer Therapy - Bone Marrow Transplant
- Trial name
- FACT-BMT (NCT01490957)
- Testing
- Database
- Where
- Saudi Arabia
- Volunteers
- 113 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Pneumonia, Pulmonary Fibrosis
Pulmonary Rehabilitation in Non-chronic Obstructive Pulmonary Disease Patients.
To determine the effect of pulmonary rehabilitation on pulmonary function in non-chronic obstructive pulmonary disease patients.To determine the effect of pulmonary rehabilitation on health related quality of life in non-chronic…
- Conditions
- Pneumonia, Pulmonary Fibrosis, Tuberculosis, Bronchiectasis
- Trial name
- NCT05174741
- Testing
- Conventional Chest Physiotherapy, Aerobic training Group
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Type 1 Diabetes
Dietary Fat and Endothelial Function in Type 1 Diabetes
The purpose of this study is to evaluate the effects of the add-on of extra vergin olive oil or butter to a high glycemic index meal on endothelial function in subjects with type 1 Diabetes and healthy subjects.
- Trial name
- NCT04812782
- Testing
- EVOO supplementation, Butter supplementation
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Cystic Fibrosis
Effect of the CFTR-modulating Triple Therapy Elexacaftor - Tezacaftor - Ivacaftor
The aim of this study is to investigate the frequency distribution, cytokine profile and function of peripheral, mononuclear leukocyte populations (monocytes, NK cells, T/B lymphocytes) and their correlation to clinical and…
- Trial name
- NCT05576324
- Testing
- Elexacaftor / Ivacaftor / Tezacaftor
- Where
- Germany
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Breast Cancer, Lymphoma
Assessment of Cognitive Function in Breast Cancer and Lymphoma Patients Receiving Chemotherapy
Cognitive impairments in cancer patients represent an important clinical problem. Studies to date estimating prevalence of difficulties in memory, executive function, and attention deficits have been limited by small sample sizes…
- Trial name
- CANTAB (NCT01382082)
- Where
- 29 sites in United States
- Volunteers
- 1,432 people, healthy volunteers welcome
- Sponsor
- University of Rochester NCORP Research Base
Ventricular Dysfunction, Asthma in Children
Evaluation of Cardiac Biomarkers and Ventricular Function in Asthmatic Children
Evaluation of cardiac biomarkers and the left and right ventricular systolic and diastolic function in asthmatic children in Assuit university hospital
- Trial name
- NCT05985720
- Volunteers
- 50 people
- Sponsor
- Assiut University
Asthma, Wheezing
Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation
In a randomized clinical trial (RCT) published in JAMA, the investigators have provided evidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates the effects of maternal smoking during pregnancy on…
- Conditions
- Asthma, Wheezing, In Utero Nicotine, Pulmonary Function
- Trial name
- VCSIP-ECHO (NCT03206710)
- Testing
- No current intervention
- Where
- 2 sites in United States
- Volunteers
- 395 people
- Sponsor
- Oregon Health and Science University
Delirium, Sleep Disorders, Circadian Rhythm
Study of Sleep and Delirium in the Intensive Care Unit (ICU)
The investigators will perform a prospective, cohort study of 100 older intensive care unit (ICU) patients, to investigate the association between sleep disruption and ICU delirium.
- Trial name
- SID (NCT01280097)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of California, San Francisco
Juvenile Idiopathic Arthritis
OHRQoL Evaluation After Functional Therapy in JIA Patients
The aim of the study was to determine the changes in Oral Health-Related Quality of Life (OHRQoL) in patients with juvenile idiopathic arthritis (JIA) and temporomandibular joint (TMJ) disorders who underwent functional therapy…
- Trial name
- NCT03008681
- Testing
- Andresen functional removable orthodontic appliance
- Where
- Italy
- Volunteers
- 93 people
- Sponsor
- University of Messina
Radiotherapy, Inflamation
Effects of Moderate-intensity Interval Aerobic Exercise (MIIAE) on Inflammatory, Immune, Metabolic, Physical Fitness, and Quality of Life Parameters in Breast Cancer Patients Undergoing Radiotherapy.
Breast cancer and its treatment with radiotherapy may be associated with systemic inflammatory, hematological, cardiac, body composition, functional and quality-of-life alterations.
- Conditions
- Radiotherapy, Inflamation, Immune System, Physical Fitness
- Trial name
- NCT07583719
- Testing
- Moderate-Intensity Interval Aerobic Exercise
- Volunteers
- 40 people
- Sponsor
- Universidad Francisco de Vitoria
Asthma, Respiratory Sounds
Treatment of Persistent Wheezing in Infants and Children
Wheezing is a high-pitched whistling sound that is produced when air flows through narrowed lung airways. It is a common symptom of asthma.
- Trial name
- NCT00301171
- Testing
- Inhaled Fluticasone
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
HIV Infections
Developing a Functional Cure for HIV Disease: Clinical Specimen Collection From HIV Positive Individuals
Clinical specimens are required from HIV positive individuals with viremia controlled by antiretroviral therapy to complete process development for a genetically modified autologous T cell product, AGT103-T.
- Trial name
- NCT03215004
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- American Gene Technologies International Inc.
Asthma, Asthma Exacerbations
Vitamin D In the Prevention of Viral-induced Asthma in Preschoolers
In this 7-month randomized controlled trial, children aged 1 to less than 6 years, with recurrent asthma attacks triggered mostly by colds, will receive a high dose of vitamin D or a placebo every 3.5 months during their usual…
- Conditions
- Asthma, Asthma Exacerbations, Preschool Child, Vitamin D
- Trial name
- DIVA (NCT03365687)
- Testing
- Vitamin D
- Where
- 9 sites in Canada
- Volunteers
- 323 people
- Sponsor
- Professor Francine Ducharme
Type 1 Diabetes
Artificial Pancreas - Adolescent Physiology & Psychology Longitudinal Evaluation
This study designed to assess changes in control of Type 1 Diabetes in pubertal adolescents over a two year period. There are two arms/substudies, the first being a longitudinal randomized controlled trial and the second an…
- Trial name
- AP APPLE (NCT04510506)
- Testing
- Artificial Pancreas (AP)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Virginia
Multiple Sclerosis
Functional Electrical Stimulation for People With Multiple Sclerosis Who Experience Foot Drop
People with Multiple Sclerosis (pwMS) often experience 'foot-drop' which means that the foot is not adequately lifted during the so-called swing phase (foot is off the ground) during walking which can lead to trips and falls.
- Trial name
- NCT01914016
- Testing
- prolonged walk
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Queen Margaret University
Neoplasm, Plasma Cell, Lymphoma
Impact of Chemotherapeutic Treatments in Patients Aged 75 Years and Over Treated for Lymphoid Hematological Malignancy
The aim of the study is to assess the prevalence of functional decline in elderly patients treated with chemotherapy or immunochemotherapy for lymphoid hematologic malignancies.
- Trial name
- LYMPHOLD (NCT05101759)
- Testing
- Comprehensive Geriatric Assessment
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
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