Clinical trials: Impacted Third Molar
Impacted Mandibular Third Molar Extraction
Submucosal Dexamethasone for Control of Post-operative Pain, Trismus, and Swelling After Mandibular Third Molar Surgery
Purpose: The aim of this study is to determine the efficacy of submucosal injection of dexamethasone in reducing pain, swelling and trismus, thus to minimize patient's discomfort after surgery, so that the patients could pursue…
- Trial name
- NCT07258498
- Testing
- Dexamethasone, Normal Saline
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- PAEC General Hospital, Islamabad
Pain
Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third Molars
This is a single centre, randomised, double-blind, double-dummy, parallel group, multiple-dose, active and placebo-controlled efficacy study to evaluate the efficacy and safety of 2×300mg ibuprofen Prolonged Release (PR) tablets…
- Trial name
- NCT03785756
- Testing
- Ibuprofen 300 mg Oral Tablet, Ibuprofen 200 mg Oral Tablet
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Mouth and Tooth Diseases, Tooth, Impacted
Ketamine on Acute Pain in Females and Males
The purpose of the study is to determine whether equal subanesthetic doses of racemic ketamine is equally effective on females and males after surgical removal of third molars
- Trial name
- NCT00232492
- Testing
- Ketamine 0,1 mg/kg males, Ketamine 0,3 mg/kg males, Ketamine 0,5 mg/kg males
- Where
- Norway
- Volunteers
- 128 people
- Sponsor
- Ullevaal University Hospital
Impacted Third Molar Tooth
Extraction of Impacted 3rd Molars, Can Bone Support of the Second Molar be Promoted by a Bio-Oss Graft?
A prospective study examining bilateral 3rd molar extraction, by a split mouth protocol the investigators augment unilaterally and compare periodontal parameters in between.
- Trial name
- NCT02753439
- Testing
- Geistlich Bio Oss
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Tooth, Impacted, Molar, Third
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement
The purpose of this study is to test whether the two MMPs can be up-regulated during orthodontic treatment. Alveolar bone samples will be collected from partially impacted third molars after orthodontic uprighting for different…
- Trial name
- NCT00154518
- Testing
- Orthodontic treatment
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Alveolar Bone Loss, Periodontal Attachment Loss
Bone Height and Extractions Study
A coronectomy is often chosen over complete extraction of a lower third molar when the tooth appears to be in close proximity to the inferior dental (ID) canal, as assessed on a plain radiograph or a cone beam computer tomograph…
- Conditions
- Alveolar Bone Loss, Periodontal Attachment Loss, Periodontal Pocket
- Trial name
- NCT03909568
- Testing
- Third molar surgery
- Volunteers
- 50 people
- Sponsor
- King's College London
Acute Pain
Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction
This study aims to evaluate the analgesic efficacy of single and multiple doses of a new fixed dose combination of nefopam hydrochloride 30 mg and paracetamol 500mg taken orally in comparison to each single component.
- Trial name
- NCT04622735
- Testing
- nefopam hydrochloride 30mg / paracetamol 500mg X2, Paracetamol 500 Mg Oral Tablet X2, Nefopam HCl 30 MG Oral Tablet X2
- Where
- 19 sites in Belgium, France and 3 more
- Volunteers
- 321 people
- Sponsor
- Unither Pharmaceuticals, France
Healthy Subjects, Hyperalgesia
Effect of High-dose Naloxone Following Third Molar Extraction
Recent studies have focused on the role of endogenous opioids on central sensitization. Central sensitization is known to be impaired or altered in chronic pain conditions, as fibromyalgia or chronic tension headache.
- Conditions
- Healthy Subjects, Hyperalgesia, Inflammations, Endodontic, Pain, Acute
- Trial name
- TME (NCT02976337)
- Testing
- Naloxone, Normal Saline
- Where
- Denmark
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- mads u werner
Dental Anxiety, Hemodynamic
Anxiety and Hemodynamic Changes in Third Molar Extraction After Patient Education
This randomized clinical trial investigates the effect of different preoperative patient information strategies on anxiety levels and hemodynamic responses during third molar extraction.
- Conditions
- Dental Anxiety, Hemodynamic, Molar, Third, Tooth Extraction
- Trial name
- NCT07018115
- Testing
- Basic Preoperative Information, Detailed Verbal Preoperative Information, Visual Preoperative Information (2D Animation)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Ummugulsum Coskun
Impacted Third Molar Tooth
Impact of Antibiotic Treatment and Extraction on the Oral Micro Biome
This is a prospective, longitudinal, observational, cohort study investigating young adults undergoing surgical extraction of a wisdom tooth with and without antibiotics post-operatively.
- Trial name
- NCT02951676
- Testing
- Extraction
- Where
- China
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Postoperative Morbidity, Trauma
Fruit And Vegetables and OUtcomes After Removal of Impacted TEeth
The proposed study will test the following hypotheses: 1. Pre-operative daily dual supplementation with Juice Plus+ (fruit \& vegetable) for 11 weeks will result in reduced post-operative morbidity in terms of quality of life…
- Conditions
- Postoperative Morbidity, Trauma, Wound Healing
- Trial name
- FAVOURITE (NCT01145820)
- Testing
- Juice plus
- Where
- United Kingdom
- Volunteers
- 246 people
- Sponsor
- University of Birmingham
Trismus, Edema
Low Laser Light Therapy After Impacted Third Molar Removal
Third molars extraction is a surgery frequently performed in dentistry. It is generally associated to a great postoperative distress rendered by pain, swelling and trismus, caused by surgical trauma inflammation.
- Conditions
- Trismus, Edema, Pain
- Trial name
- NCT02602431
- Testing
- Extra-oral laser irradiation, Intra-oral laser irradiation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Edema Face, Scanning Devices
Lidar-based Scanning of Fascial Edema (FE)
This study compared handheld and mechanically assisted scanning to evaluate fascial edema after third molar extraction. The flexible ruler served as the reference.
- Trial name
- FE (NCT07690488)
- Testing
- Measurement with flexible ruler, Measurement with handheld scanning, Measurement with mechanically assisted scanning
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ege University
Impacted Third Molar Tooth
EFFICACY OF ICE PACK THERAPY AFTER IMPACTED THIRD MOLAR SURGERY
this study evaluates the effect of cold application after impacted third molar extractions. Patients have bilateral impacted third molar tooth included in this study.
- Trial name
- NCT03261869
- Testing
- Cold application
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Baskent University
Impacted Third Molar Tooth
Effect of Honey and Dexamethason on Extraction Healing
Natural honey and dexamethason will be given before impaction removal then postoperative complications will be evaluated
- Trial name
- NCT04848259
- Testing
- Normal saline, Dexamethasone, Honey
- Where
- Saudi Arabia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Third Molars Extraction, Low Level Laser Therapy
Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction
Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure.
- Conditions
- Third Molars Extraction, Low Level Laser Therapy, Bone Healing
- Trial name
- NCT07190950
- Testing
- Low Level Laser Therapy
- Where
- Vietnam
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Trigemino-Cardiac Reflex, Impacted Third Molar Tooth
The Frequency of Trigeminocardiac Reflex During the Extraction of Impacted Mandibular Wisdom Teeth
The goal of this clinical trial is to investigate trigeminocardiac reflex (TCR) formation during surgical extraction of mandibular impacted wisdom teeth in healthy adults.
- Trial name
- NCT06499532
- Testing
- Monitoring and Surgical removal of mandibular impacted wisdom teeth, using Gow-Gates anesthesia technique, Monitoring and Surgical removal of mandibular impacted wisdom teeth, using inferior alveolar nerve block anesthesia technique
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Wound Heal, Quality of Life
Clinical Wound Healing After Lower 3rd Molar Fully-impacted Surgery With 2 Types of Flap
The dehiscence distal to the second molar after lower third molar extraction is very common because the access flap for surgical extraction cannot be repositioned on a portion of healthy bone to guarantee suture support.
- Conditions
- Wound Heal, Quality of Life, Dehiscence
- Trial name
- NCT04314765
- Testing
- lower third molar extraction
- Where
- Italy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Impacted Third Molar Tooth
Evaluation of the Effects of Silk and Polyester Suture on Postoperative Complications
Some undesirable complications such as pain, swelling, trismus, paresthesia, hematoma, infection and, albeit rare, fractures may occur after lower impacted wisdom tooth surgery.
- Trial name
- NCT05534204
- Testing
- Silk suture, Polyester suture
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Impacted Third Molar Tooth, Healing Surgical Wounds
Evaluation of Hydrogen Peroxide and Hyaluronic Acid (BMG0703) in the Healing of Post-extraction Sites
A clinical study to evaluate the efficacy and safety of a mouthwash containing Hydrogen Peroxide, Sodium Hyaluronate and Glycine in the healing of post-extraction sites of wisdom teeth by film forming action.
- Trial name
- NCT04438434
- Testing
- Filming Formulation of Hydrogen Peroxide and Hyaluronic Acid, Chlorhexidine mouthwash
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- University of Milan