Clinical trials: Impaired Health
Physical Disability
Feasibility of An Active Video Gaming Intervention
Replacing sedentary behaviors during leisure time with active video gaming (AVG) has been shown to be an enjoyable option for increasing the amount of physical activity acquired each week.
- Trial name
- NCT05310279
- Testing
- GAIMplank
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Upper Extremity Impairments, Cerebral Palsy (CP)
Obi Medical Robot: Evaluating Effectiveness Related to Usability
This mixed-methods usability study evaluates the effectiveness of the Obi Gen 3 robotic feeding device in meeting user needs among providers, caregivers, and patients.
- Conditions
- Upper Extremity Impairments, Cerebral Palsy (CP), ALS - Amyotrophic Lateral Sclerosis, Rett Syndrome
- Trial name
- NCT07151950
- Testing
- One-week trial of Obi Medical device, which provides robotic assistance with feeding to persons with upper extremity impairments who are unable to self-feed in the traditional manner using utensils
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Desin LLC
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Mild Cognitive Impairment (MCI), Cognitive Training
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial
Effective, clinically meaningful treatments are lacking for patients with mild cognitive impairment (MCI), which is associated with increased risk of transition to dementia.
- Trial name
- COGIT-2 (NCT06601933)
- Testing
- Cognitive Training
- Where
- 4 sites in United States
- Volunteers
- 240 people
- Sponsor
- Columbia University
Stroke Patients
Effect of BRACE on Balance, Cognition and Mobility Among Stroke Patients
The Objective of the is to determine effect of balance, resistance, aerobic, cognitive exercises (BRACE) protocol on balance, cognition and mobility among stroke patients and to compare the effect of Balance, Resistance, Aerobic…
- Trial name
- NCT06663709
- Testing
- BRACE, TASK-oriented
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Psoriasis
The Quality of Life Study in Psoriasis Patients After Ustekinumab Treatment
This study aims to see if patient quality of life can be approved after treatment with an injectable medication called ustekinumab for the treatment of generalized psoriasis.
- Trial name
- NCT01511315
- Testing
- Ustekinumab
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of California, San Francisco
Mild Cognitive Impairment, Subjective Cognitive Decline
Efficacy of a Multicomponent Cognitive Intervention in Adults With Subjective Cognitive Decline and Mild Cognitive Impairments
Individuals with mild cognitive impairment (MCI) and subjective cognitive decline (SCD) have greater risk of developing dementia.
- Trial name
- NCT04023032
- Testing
- multicomponent cognitive intervention
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- National Taiwan University Hospital
Prediabetes, Hyperglycemia
Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes - Main Study
Sweetch is a personalized mobile-health platform coaching system (mobile phone app) designed to promote adherence to physical activity guidelines for people with prediabetes.
- Conditions
- Prediabetes, Hyperglycemia, Postprandial Hyperglycemia, Impaired Glucose Tolerance
- Trial name
- NCT03315663
- Testing
- Sweetch App & DBWS, Sweetch App Alone
- Where
- 2 sites in United States
- Sponsor
- Johns Hopkins University
Cerebral Palsy, Child, Preschool
Effect of Power Wheelchairs on the Development and Function of Young Children With Severe Physical Disabilities
Self-produced locomotion often is limited in children with cerebral palsy and other conditions that cause severe motor impairments.
- Trial name
- NCT01115998
- Testing
- Power wheelchair, No power wheelchairs
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Oklahoma
Depression, Anxiety, Visual Impairment
Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss
The goal of this study is to develop and pilot test a therapeutic strategy combining cognitive behavioral therapy (CBT) with mindfulness practices tailored for individuals adjusting to vision loss.
- Conditions
- Depression, Anxiety, Visual Impairment, Adjustment, Adjustment Disorder With Anxious Mood
- Trial name
- NCT07073521
- Testing
- Integrated Cognitive Behavioral Therapy (CBT) & Mindfulness Group Intervention for Adjustment to Vision Loss
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Chicago Lighthouse
Mild Traumatic Brain Injury, Posttraumatic Stress Disorder
Imaging Biomarkers of Mild Traumatic Brain Injury: a Longitudinal Cohort Study
This longitudinal cohort study aims to detect the topographical nature of the white matter microstructure and resting state functional connectivity patterns across the whole brain in the evolution of pathology as a function of…
- Conditions
- Mild Traumatic Brain Injury, Posttraumatic Stress Disorder, Affective and Somatic Complaints, Cognitive Impairments
- Trial name
- NCT02868684
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Parkinson Disease, Multiple Sclerosis
Turkish Version of Mini-BESTest, Validity and Reliability for Adult Participants With Sensoriomotor Impairments
The aim of this study is to present the Turkish version of miniBESTest which evaluates the reasons of balance deficit and postural control.
- Conditions
- Parkinson Disease, Multiple Sclerosis, Trauma, Brain
- Trial name
- NCT03839381
- Volunteers
- 50 people
- Sponsor
- Ordu University
Psychological Stress, Psychosocial Impairment
Evaluation of the Psychosocial Impact on Health Professionals Exposed During COVID 19 Coronavirus Pandemic
Application of a survey in electronic support to hospital professionals. This survey will include different demographics as well as questions from own elaboration about the different aspects related to the development of work…
- Conditions
- Psychological Stress, Psychosocial Impairment, Anxiety, Depression
- Trial name
- NCT04752839
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
HIV/AIDS, Cognitive Impairment
A Randomized Pilot Trial Evaluating the Impact of a Yoga Intervention on Cognition in Older Adults Infected With HIV
Approximately 50% of people living with HIV (and as many as 80% over the age of 50) have difficulties with cognitive functions such as memory and thinking that can have a profound negative impact on activities of daily living and…
- Conditions
- HIV/AIDS, Cognitive Impairment, Aging, Mobility Limitation
- Trial name
- NCT03071562
- Testing
- Yoga-mindfulness
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Adria Quigley
Type 2 Diabetes
Oral Health Parameter-Based Diabetes Type 2 Indication Using Machine Learning
This study aims to explore the potential of using machine learning (ML) algorithms to predict Diabetes type2, based on oral health and demographic data.
- Trial name
- JFG (NCT06981286)
- Testing
- A dataset comprising participants withT2D will be used to evaluate the classification performance of various machine learning techniques.
- Where
- Sweden
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Patient Satisfaction, Neurocognitive Disorders
COgilus Remediation in Alzheimer Patients (CORA)
This study evaluates the usability of a new tablet PC application to stimulate cognitive functions. Patients hospitalized in a geriatric ward (day or complete hospitalisation) but also their informal and professional caregivers…
- Trial name
- CORA (NCT04113577)
- Testing
- usability survey
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Psychosomatic Disorder, Psychological Distress
Feasibility and Benefits of Digital Services During the COVID19 Pandemic
As a result of the pandemic, hygiene and distancing rules must be followed in Health care/ rehabilitation clinics to ensure the safety of patients and staff.
- Conditions
- Psychosomatic Disorder, Psychological Distress, Psychological Stress, Psychological Disease
- Trial name
- AnhandCOV19 (NCT04453475)
- Testing
- Training session adressing information and health literacy
- Where
- Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Temporomandibular Disorders (TMD), Disc Displacement
Differential Impact of TMJ Disc Displacement and Muscle Disorders on Pain, Function, and Quality of Life in TMD Patients
This study aims to explore the relationship between the position of the temporomandibular joint (TMJ) disc and key clinical outcomes in patients with temporomandibular disorders (TMD).
- Conditions
- Temporomandibular Disorders (TMD), Disc Displacement, Functional Impairment
- Trial name
- DPTMD (NCT06758479)
- Where
- India
- Volunteers
- 100 people
- Sponsor
- King Khalid University
Mental Health Impairment
Investigating the Impact of the Mental Health First-Aid Training Course in Danish Employees
The purpose of the study is evaluate the effect of the Mental Health First-aid training course on a Danish population of employees.
- Trial name
- NCT02334020
- Testing
- Mental Health First-aid
- Where
- Denmark
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Cocaine Use Disorder (CUD), Cognitive Impairments
The Role of Potassium Channels in Working Memory Impairments of Chronic Cocaine Users
The study aims to address the neurobiological basis of cognitive impairments in chronic cocaine users by investigating the potential impact of an acute potassium channel blockade on working memory performance and other cognitive…
- Trial name
- POTCHICUD (NCT07532460)
- Testing
- 4-aminopyridine (4-AP)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Boris Quednow