Clinical trials: Implant Osseointegration
Implant Stability
Stability Of Dental Implants Placed In Healed Bony Sites Of Hyperlipidemic Patients: A Case Series
Statement of the problem: Osseo-integration of dental implants depends mainly on bone regeneration around dental implant. Hyperlipidemia has significant adverse effects on bone health, leading to lower bone mineral density and to…
- Trial name
- NCT04718246
- Testing
- Dental Implants Placed In hyperlipidemia patients
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Cairo University
Dental Implant
Effect of Vitamin D3 Supplementation on Serum Sphingosine-1-Phosphate Levels and Dental Implant Osseointegration: A Prospective Study
This study aims to evaluate whether vitamin D3 supplementation can promote dental implant osseointegration by increasing serum sphingosine-1-phosphate (S1P) levels.
- Trial name
- NCT07883811
- Testing
- Vitamin D3 ( Colecalciferol)
- Volunteers
- 60 people
- Sponsor
- Air Force Military Medical University, China
L-PRF, Dental Implants
Evaluation of the Effect of Leucocyte Platelet-Rich Fibrin (L-PRF) Technique Applied in Post-extraction Sockets Before Placement of Dental Implants
Aim of study: The application of L-PRF membrane in post-extraction sockets outmatches the use of a) allograft covered with a collagen fleece b) allograft combined with L-PRF membrane c) natural healing, with reference to bone…
- Conditions
- L-PRF, Dental Implants, Osseointegration, Alveolar Bone Grafting
- Trial name
- NCT07387913
- Testing
- Allograft and collagen membrane, Allograft and L-PRF membrane, L-PRF
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Dental Implant Failed, Pre-osseointegration Failure of Dental Implant
Evaluation of the Stability of Implants With Two Different Surface Treatments
The aim of this study is to compare the stability of dental implant surface treated by sandblasting abrasive particles and acid subtraction (Control) with hydrophilic surfaces dental implants (chemical) and with a higher surface…
- Trial name
- NCT02134743
- Testing
- Implant surgery
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Osseointegration Failure of Dental Implant Due to Infection, Osseointegration Failure of Dental Implant Prior to Intentional Prosthetic Loading
Two-Piece Zirconia Dental Implant vs Two-Piece Titanium Dental Implant- Randomized Clinical Control Trial
2 Arms (60 subjects - 30 each arm). Experimental group with two-pice zirconia dental implant and Control group with two-piece titanium dental implant Evaluate Changes in inflammatory and microbiology levels from T0 (baseline) T2…
- Trial name
- NCT03336723
- Testing
- Dental Implant
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Different Surgical Techniques in Dental Implant Surgery
Effect of Different Drilling Techniques on Primary Stability and Marginal Bone Loss of Extra Short Implants
Our aim in this study is to compare the effects of low-speed drilling surgery technique without irrigation and conventional implant surgery technique with irrigation on extra short implants.
- Trial name
- NCT06234566
- Testing
- Conventional dental implant surgery, Low Speed Drilling Without Irrigation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Marginal Bone Loss, One-piece Implants Versus Two-piece Implants During the Osseointegration Phase
Comparative Evaluation Between One-piece and Two-piece Implants Supporting Mandibular Screw-retained All-On-Four Full-arch Prosthesis on Peri-implant Bone Changes.
Evaluating the bone changing after receiving one-piece implants supported full arch prosthesis compared to the conventional two-piece implants.
- Trial name
- RCT (NCT06790524)
- Testing
- One-piece dental implants with MUA, Two-piece dental implants
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Deficiency, Vitamin D
Effect of Vitamin D Replacement on Bone Healing in Mini-dental Implants
1. Title 2. Executive team 3. Research line 4. Summary 5. Research problem 6. Justification 7. Literature review 8. Objectives 9. Materials and methods 10. Dissemination of knowledge generated 11. Schedule of activities 12.
- Trial name
- NCT03356730
- Testing
- Vitamin D
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade de Passo Fundo
Osseointegration Failure of Dental Implant
A Randomised Control Clinical Trial Investigating the Effect of H-PRF on Implant Stability and Marginal Bone Levels
This research will be a randomised controlled trial (RCT) investigating whether the use of Horizontal Platelet Rich Fibrin (H-PRF) increases implant stability compared to those implants placed without H-PRF, and therefore…
- Trial name
- NCT06453330
- Testing
- Horizontal platelet-rich fibrin (H-PRF)
- Where
- Ireland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Dental Implants , Osseointegration , Marginal Bone Loss , Implant Stability
Effect of Locally Applied Simvastatin Gel on Dental Implant Stability and Marginal Bone Level
stability and marginal bone level. Forty-two patients received dental implants and were randomly assigned to two groups. In the test group, 1.2% simvastatin in 4% methylcellulose gel was applied around the implant, while in the…
- Trial name
- NCT07194447
- Testing
- Simvastatin Gel, Methylcellulose Gel
- Where
- Iraq
- Volunteers
- 42 people
- Sponsor
- Maha Zuhair
Prosthesis Migration, Amputation
Evaluation of the Stability of Osseointegrated Implant in Amputees
The study concerns the technique of osseointegration that consists of inserting a titanium pin into the bone of the amputated limb.
- Trial name
- METACOS (NCT03836755)
- Testing
- Metacos
- Where
- Italy
- Volunteers
- 4 people
- Sponsor
- Istituto Ortopedico Rizzoli
Dental Implants, Dental Implants , Osseointegration , Marginal Bone Loss , Implant Stability
Periosteal Sutures Versus Titanium Tacks for Guided Bone Re-generation in the Aesthetic Zone: a Pilot Randomized Controlled Trial
This randomized controlled clinical study, titled "Periosteal sutures for fixation of composite bone substitutes in guided bone regeneration: a randomized controlled clinical study," is being conducted at the Dental Unit of…
- Conditions
- Dental Implants, Dental Implants , Osseointegration , Marginal Bone Loss , Implant Stability, Maxillary Alveolar Reconstruction
- Trial name
- NCT07330232
- Testing
- Periosteal mattress sutures for graft/membrane stabilization in guided bone regeneration Titanium tacks for graft/membrane stabilization in guided bone regeneration
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- University of Chile
Dental Implant
Low-Level Diode Laser Therapy on the Acceleration of Osseointegration Around Delayed Dental Implant
Good quality soft tissue determines the possibility not only to obtain full primary wound closure during the bone defect reconstruction, but also assures effective implant treatment and stability of peri-implant…
- Trial name
- NCT07536451
- Testing
- Dental implant + LLDL, Dental implant
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Hams Hamed Abdelrahman
Osseointegration Failure of Dental Implant
Immediate Loading and Fully Guided Surgery: Single Implants
To evaluate the overall treatment outcome of single implants installed with the assistance of fully guided-surgery, submitted to immediate loading with restorations fabricated with the help of intraoral scanning, during a 1-year…
- Trial name
- NCT04061694
- Testing
- Immediate loading, fully guided surgery and 3D printed restoration, Immediate loading
- Where
- Sweden
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Folktandvården Skåne AB
Dental, Implant Osseointegration
Validity of Ozonated Olive Oil Gel Versus Injectable Bone Graft
Many of studies have been performed to improve osseointegration and bone density around implants by modifying the implant by adding bone graft or substitute material that increase success of implant.
- Conditions
- Dental, Implant Osseointegration, Ozone Therapy, Bone Graft
- Trial name
- NCT07368114
- Testing
- Immediate implant placement, β-tricalcium phosphate Injectable Bone Graft, Ozonated olive oil gel
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Partial Edentulism, Dental Implant Placement
Effect of Advanced PRF and Hyaluronic Acid on Dental Implant Healing
This randomized parallel-group clinical trial aimed to evaluate the clinical efficacy of advanced platelet-rich fibrin (A-PRF) combined with hyaluronic acid (HA) in enhancing peri-implant bone formation in patients undergoing…
- Trial name
- NCT07792720
- Testing
- Delayed Dental Implant Placement, Advanced Platelet-Rich Fibrin (A-PRF), Hyaluronic Acid 1.5%
- Where
- Yemen
- Volunteers
- 30 people
- Sponsor
- Samar Ali Abdu Salamah
Amputation
e-OPRA Implant System for Lower Limb Amputees
The e-OPRA Implant System, is a further development of the OPRA (Osseointegrated Prostheses for the Rehabilitation of Amputees) Implant System, approved under HDE (Humanitarian Device Exemption) H080004.
- Trial name
- NCT03720171
- Testing
- e-OPRA Implant System
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Integrum
Osseointegration Failure of Dental Implant, Periimplantitis
Prospective Longitudinal Clinical Study for the Evaluation of Peri-implant Tissue and Osseointegration After Rehabilitation With Osseointegrated Implants
The success of rehabilitation with osseointegrated implants is associated with numerous factors, including patient characteristics, installed implants, proper planning, and the prosthetic connections used.
- Conditions
- Osseointegration Failure of Dental Implant, Periimplantitis, Peri-Implant Tissues, Peri-Implant Health
- Trial name
- Dental Implant (NCT06967649)
- Testing
- TITANIUM IMPLANT
- Where
- Brazil
- Volunteers
- 350 people
- Sponsor
- Universidade Federal Fluminense
Dental Implant
Investigating Implant Surface Effect on Osseointegration: NGA vs. ModSLA
This study aims to characterise the stability of crestal bone levels one year after loading, the associated aesthetic outcomes, immunological response, prosthodontic outcomes as well as overall patient reported outcome measures…
- Trial name
- NCT06086873
- Testing
- Implant Type
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Guided Bone Regeneration
A Phase I Study of SB Cell for the Enhanced Osseointegration of Guided Bone Regeneration in Implant Surgery
This is a Phase 1 study to evaluate the safety profile of autologous-derived SB cells to enhance osseointegration of GBR in patients undergoing dental implant surgery.
- Trial name
- NCT04451486
- Testing
- SB cells
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University