Clinical trials: Implantation Failure
Missing Tooth, Osseointegration Failure of Dental Implant
X-space Implants in Post-extraction Sites.
Several recent systematic reviews have highlighted how the macrodesign of dental implants can influence stress distribution and biomechanical and biological behavior in implants immediately inserted in post-extraction sites.
- Trial name
- NCT04492111
- Testing
- post-extraction dental implant
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bari
Failure of Osseointegration of Dental Implant
Survival and Success of MIS C1 Implants- a Field Study
The aim of the present study is to evaluate the 1-year and 3-year survival and success of MIS® C1 implants with a length of 10-15mm. Specific Aims 1. To study 1-year and 3-year implant survival rate C1 implants 2.
- Trial name
- NCT01707108
- Testing
- Dental Implant (MIS Technologies)
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Bone Loss, Alveolar, Resorption, Bone
The Effect of Growth Factor on Implant Osseointegration
In this study, concentrated growth factor obtained by centrifuging the patient's own blood and advanced platelet-rich fibrin liquids were applied to the implant cavity and surface.
- Conditions
- Bone Loss, Alveolar, Resorption, Bone, Osseointegration Failure of Dental Implant
- Trial name
- NCT04879446
- Testing
- Concentrated growth factor(CGF), Advanced platelet rich fibrin (A-PRF), Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Uğur Can ÜNLÜGENÇ
Pregnancy Complicated by Low Implantation
Intralipid Therapy for Recurrent Implantation Failure and Recurrent Miscarriages: Is it a Hope or Myth?A Randomized Clinical Trial
Both organ-specific and systemic autoimmunity are associated with an increased prevalence of recurrent miscarriage and reproductive failure, rendering the role of the maternal immunological system in fertility a key concept.
- Trial name
- ILRIFRM (NCT01679561)
- Testing
- intralipid
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Implant Tissue Failure
Effects of ABO Blood Types on the Survival and Marginal Bone Resorption of Dental Implants
This study evaluates implant survival and marginal bone resorption in patients receiving implant treatment with respect to demographic data and AB0 (groups) blood types.
- Trial name
- NCT04054271
- Where
- Turkey (Türkiye)
- Volunteers
- 963 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Post-osseointegration Biological Failure of Dental Implant, Alveolar Bone Loss
The Influence of Mucosal Tissue Thickness on Soft and Hard Tissue Changes Around Implants
Crestal bone and soft tissue stability around implants is an important issue in implant dentistry. Initial vertical mucosal tissue thickness was shown to be one of the factors having impact on bone stability.
- Trial name
- NCT02580721
- Testing
- Dentsply Astra Tech Implant System EV
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Prosthesis Durability
Impact of Mandibular Overdenture Base Construction Techniques on Assessment of Occlusion
This within patient study will be conducted to compare between two different construction techniques (CAD-CAM Milled and Conventional techniques) of 4-implant-assisted complete mandibular overdenture bases regarding the digital…
- Trial name
- NCT06080815
- Testing
- CAD/CAM Complete denture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Repeated Implantation Failure, Normal Fertile
Uterine Microbiome in Women with Repeated Implantation Failure and Normal Fertile Women
Characterization of the uterine microbiome in women with repeated implantation failure as well as in normal fertile women.
- Trial name
- NCT03405883
- Testing
- Vaginal swab + endometrial biopsy
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Peri-Implantitis, Peri-implant Mucositis
Characterizing the Inflammation Around Dental Implants
The use of titanium dental implants has become a common modern treatment to restore teeth. Although the success rate of dental implants is high, inflammation around the dental implant still occurs.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Implant Site Reaction, Implant Site Infection
- Trial name
- NCT05675241
- Testing
- Clinical examination of a dental implant, Radiological Examination, Peri-implant crevicular fluid sample collection
- Where
- Canada
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- McGill University
Infertility
Intralipid Therapy for Women 35-40 Years With Positive Natural Killer Cells Undergoing Intracytoplasmic Sperm Injection (ICSI)
Intralipid can suppress natural killer cells that are known to be involve in repeated implantation failure and recurrent miscarriages.Intralipid is made of purified soybean oil, egg phospholipids, glycerol and water.
- Trial name
- NCT01916798
- Testing
- Intralipid infusion
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Implant Failed, Dental Prosthesis Failure
Peri-implant Tissues in BLX® Implants
This is a randomized triple-blind clinical trial to evaluate the behavior of peri-implant tissues (bone and soft tissues) in BLX implants loaded early or delayed and with different surgical milling protocols.
- Trial name
- BLX (NCT03720236)
- Testing
- Implant bed preparation protocol, Implant loading
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Failure of Dental Prosthesis
Comparison of Two Implant Prosthetic Pathways
To assess and compare the esthetic outcome and clinical performance of anterior maxillary all ceramic implant single crowns based either on prefabricated zirconia abutment veneered with pressed ceramics or on a CAD/CAM…
- Trial name
- NCT02905838
- Testing
- Anatomic e.max Abutment, CAD/CAM CARES Abutment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bern
Infertility
Intrauterine G-CSF Administration in RIF
Aim of this study is to investigate the effects of intrauterine G-CSF on endometrial thickness, clinical pregnancy rate and live birth rate in a recurrent implantation failure (RIF) group
- Trial name
- G-CSF (NCT03783208)
- Testing
- G-CSF, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Gurgan Clinic
Other Endosseous Dental Implant Failure
Effect of Immediate Placement and Loading of Compressive Versus Conventional Implants
The current study aims to compare immediate placement and loading of compressive versus conventional dental implants after atraumatic extraction regarding the effectiveness, bone resorption and survival of each of them.
- Trial name
- Implants (NCT07601347)
- Testing
- Immediate implant placement and loading
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ahmed Nagi Alghandour
Dental Implant, Dental Implant Failed
Effect of Systemic Vitamin D on Dental Implant Osseointegration
The primary goal for any oral implantologist is to obtain satisfactory healing and long-term treatment success. Osseointegration is the key to dental implant success8 and is required to achieve direct structural and functional…
- Conditions
- Dental Implant, Dental Implant Failed, Vitamin D Deficiency
- Trial name
- VIDOS (NCT07684404)
- Testing
- Vit D
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Endosseous Dental Implant Failure, Bone Loss
Compare Sterilized Clean vs Sterilized Aseptic Dental Implant Surgery
In patients that require dental implants , does performing the surgery in clean sterile field compared to aseptic field, produces more post-operatory complications, implant morbidity or patient discomfort ?
- Trial name
- NCT01970826
- Testing
- Single Dental Implants, Sterilized Aseptic, Sterilized Clean
- Where
- Portugal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Heart Failure
3D Assessment of RV Function in Patients Undergoing LVAD Implantation
This goal of this study is to analyze images of the right ventricle taken via 3D transesophageal echocardiography (TEE) during left ventricular assist device (LVAD) implantation.
- Trial name
- NCT05376254
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Dental Implant Failure
Accuracy of Computer-assisted Template-based Implant Placement Using Conventional or Digital Impression
Proper implant position has a significant impact in esthetic and functional outcomes of implant-supported restorations. Computer-assisted template-based implant placement (guided surgery) have become increasingly popular due to…
- Trial name
- NCT03764176
- Testing
- Conventional impressions, Digital impressions
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Prosthesis Durability
Direct Versus Indirect Pick up of the Locator Retentive Caps:(Within-patient Study)
The purpose of this study will be to evaluate the effect of direct and indirect pick up of the locator retentive caps and compare the clinical results with those of the manufacturer retentive force.
- Trial name
- NCT05289752
- Testing
- dental implants in the mandible, locator attachment and overdenture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Implant Tissue Failure, Dental Implant Failed
Laterally Rotated Flap for Soft Tissue Augmentation Around Maxillary Loaded Osseointegrated Dental Implant
Peri-implant mucositis is one of the most common peri-implant diseases. It was reported in more than 20% of the subjects rehabilitated with dental implants (Lee et al. 2017; Rodrigo et al. 2018; Wada et al. 2019).
- Conditions
- Implant Tissue Failure, Dental Implant Failed, Peri-Implantitis
- Trial name
- NCT06206499
- Testing
- soft tissue augmentation
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia