Clinical trials: Implants
Peri Implant Mucositis, Peri Implant Bone Loss
Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.
Introduction: Dental implants offer a durable, aesthetic, and functional option for tooth replacement. However, they are not immune to failure.
- Conditions
- Peri Implant Mucositis, Peri Implant Bone Loss, Peri Implantitis, Calcium Deficiency
- Trial name
- NCT07766707
- Where
- Spain
- Volunteers
- 192 people
- Sponsor
- University of Barcelona
Heart Failure, Heart Failure With Preserved Ejection Fraction
Assessment of CCM in HF With Higher Ejection Fraction
The AIM HIGHer Clinical Trial will evaluate the safety and efficacy of Cardiac Contractility Modulation (CCM) therapy in patients with heart failure with LVEF ≥40% and ≤70%.
- Conditions
- Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction, Heart Failure With Moderately Reduced Ejection Fraction
- Trial name
- AIM HIGHer (NCT05064709)
- Testing
- Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System, OPTIMIZER™ Smart Mini System
- Where
- 67 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Impulse Dynamics
Edentulous Patients
Immediate and Flapless Full-arch Rehabilitation of Edentulous Jaws
The study involved 28 edentulous patients (20 female/8 males; average age of 67.75± 8.627 years) rehabilitated with 33 prostheses (17 all-on-4/16 all-on-6) supported by 164 implants.
- Trial name
- NCT05307029
- Testing
- rehabilitation with fixed full-arch prosthesis
- Volunteers
- 28 people
- Sponsor
- University of Roma La Sapienza
Focal Epilepsy, Electrodes, Implanted
Multi-level Approach of Brain Activity Using Intracranial Electrodes in Epileptic Patients
The main goal of this project is to study the mechanisms of epileptic activities using intracranial macro and micro electrodes in epileptic patients undergoing pre-surgical investigation.
- Conditions
- Focal Epilepsy, Electrodes, Implanted, Cognitive Function, Neurophysiology
- Trial name
- EpiMicro (NCT04653012)
- Testing
- Intracranial macro-microelectrode recording
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Tympanostomy Tube Insertion
Prediciton of the Round Window Visibility Through Posterior Tympanotomy by CT Scan Analysis
It is difficult to predict the intraoperative visibility of the round window through the posterior Tympanostomy. In case of non-visualization, the surgeon may have to change operative technique during cochlear implant surgery.
- Trial name
- NCT03589209
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Dental Implants
Implant-related Outcomes in the Context of Maxillary Sinus Lifting
The population of interest will be recruited out of a cohort of patients who were initially treated at the Department of Oral Surgery and Stomatology between 1997 and 2001.
- Trial name
- NCT06647381
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Peri-implant Soft Tissue Deficiency, Insufficient Peri-implant Keratinized Tissue
CTG Versus Collagen Matrix for Peri-Implant Soft Tissue Augmentation
This randomized controlled trial compares two techniques for peri-implant soft tissue augmentation in the mandibular molar region: an autogenous connective tissue graft (CTG) and a collagen matrix.
- Trial name
- NCT07371481
- Testing
- Collagen Matrix, Connective Tissue Graft
- Where
- Vietnam
- Volunteers
- 46 people
- Sponsor
- Hanoi Medical University
Alveolar Ridge Preservation, Horizontal Alveolar Bone Loss
Radiographic and Histomorphometric Assessment for Alveolar Ridge Preservation Using Autogenous Tooth Graft From Extracted Tooth Combined With Simvastatin 1:1 Versus Autogenous Tooth Graft
This study will be held to overcome the previous limitations related to bone loss after teeth extraction by taking advantages from both Autogenous tooth graft and Simvastatin which will offer a promising synergistic approach for…
- Conditions
- Alveolar Ridge Preservation, Horizontal Alveolar Bone Loss, Vertical Alveolar Bone Loss, Delayed Implant
- Trial name
- ARP (NCT06879171)
- Testing
- Alveolar ridge preservation
- Volunteers
- 26 people
- Sponsor
- Cairo University
Unspecified Atrophy of Edentulous Alveolar Ridge
Immediate Implant Placement in the Esthetic Zone
This study aims to examine dimensional alveolar ridge alterations and prevent buccal plate resorption and soft tissue recession following immediate implant placement in extraction sockets in the maxillary esthetic zone using…
- Trial name
- NCT01533571
- Testing
- Immediate implant placement with simultaneous bone grafting
- Where
- 4 sites in United States, Lithuania and 2 more
- Volunteers
- 60 people
- Sponsor
- Lithuanian University of Health Sciences
Prosthesis Survival
PEEK Prostheses in the All-on-4 Concept Using Zygomatic Implants for Full-arch Rehabilitation.
The goal of this study is to evaluate the outcome of a Poly-ether-ether-ketone - acrylic resin prosthesis for full-arch rehabilitation of the atrophic maxillae through the All-on-4 Hybrid concept (standard and zygomatic implants)…
- Trial name
- PEEKPilotZyg (NCT05589545)
- Testing
- Prosthetic full-arch rehabilitation using a PEEK-acrylic resin prosthesis
- Where
- Portugal
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Malo Clinic
Neurosensory Function of Inferior Alveolar Nerve
Computer - Guided Inferior Alveolar Nerve Lateralization With Simultaneous Prosthetic Driven Implant Placement Will be Performed on 10 Surgical Sides (Mandibular Quadrants) to Evaluate the Postoperative Neurosensory Disturbances Following Guided Inferior Alveolar Nerve Lateralization
The aim of this clinical trial is to primarily evaluate the postoperative neurosensory disturbances following guided inferior alveolar nerve lateralization with simultaneous implant placement in 10 surgical sides (mandibular…
- Trial name
- IANL (NCT06961045)
- Testing
- Guided Inferior Alveolar Nerve Lateralization with Simultaneous Implant Placement
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- AYMAN M. ARAKEEP, MSc, PhD researcher
Heart Failure, ICD
SGLT2i As Anti Arrhythmic Therapy to Prevent Sudden Cardiac Deaths.
Failing heart negative remodeling alterations might provide electrical heterogeneity and cardiac remodeling, thus potentially contributing to the occurrence of ventricular arrhythmia and subsequent sudden cardiac death (SCD).
- Conditions
- Heart Failure, ICD, Diabetes Mellitus Type 2, SGLT2i
- Trial name
- NCT03366181
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Campania Luigi Vanvitelli
Posterior Capsule Opacification
Posterior Capsule Opacification (PCO) With Single Piece Hydrophobic Versus Hydrophillic Intraocular Lens (IOL)
The purpose of the study was to compare the postoperative PCO results of the single-piece hydrophobic Acrylic IOLs versus the newer generation single-piece hydrophilic Acrylic IOLs in patients undergoing bilateral cataract…
- Trial name
- NCT01125345
- Testing
- Phacoemulsification
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Implant Site Reaction
Assessment of Osseointegration Properties of Nano-Hydroxy Apatite Coated Titanium Implant
the purpose of this trial is to evaluate the osseointegration properties of nano-hydroxy apatite coated titanium implants in posterior maxilla.
- Trial name
- NCT05936775
- Testing
- nano-hydroxy apatite coated titanium implants, sandblasted large acid itched coated titanium implant
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Tooth Extraction, Tooth Extraction Site Healing
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether β-TCP (Beta-Tricalcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Conditions
- Tooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- BTCPARPBV (NCT07638319)
- Testing
- Neocement Inject P® (Beta-Tricalcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Distal Radius Fractures
Do Generic Volar Locking Plates Provide Similar Outcomes at a Reduced Cost?
Across orthopedics, the investigators will be using the generic volar locking plates for patients undergoing open reduction and internal fixation (ORIF) of the distal radius using a block schedule, meaning one month we the…
- Trial name
- NCT06343467
- Testing
- Generic Volar Locking Plate, Conventional Volar Locking Plate
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Completely Edentulous Maxilla, Horizontal Alveolar Ridge Deficiency
ALVEOLAR RIDGE SPLIT FOR FULL-ARCH MAXILLA
This retrospective study evaluated the use of the alveolar ridge split (ARS) technique in patients with a completely edentulous upper jaw who received implant-supported fixed prostheses.
- Trial name
- NCT07846475
- Testing
- Conventional Dental Implant Placement
- Volunteers
- 47 people
- Sponsor
- Karadeniz Technical University
Hearing Loss, Hearing Impairment
Evaluating Possible Improvement in Speech and Hearing Tests After 28 Days of Dosing of the Study Drug AUT00063 Compared to Placebo (QuicKfire)
The objective of this pilot study is to explore whether repeat doses of AUT00063 can provide an indication of improvement in performance of tests across a battery of speech and hearing assessments in cochlear implant users.
- Trial name
- NCT02832128
- Testing
- AUT00063
- Where
- 4 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- Autifony Therapeutics Limited
Edentulous Alveolar Ridge, Complete Edentulism
Using Two Different Attachments in Mandibular Implant Overdenture Cases in Order to Retention and Patient Satisfaction
The Goal of the clinical trail is to evaluate the efficacy of Bar- OT Equator attachment on retention and patient satisfaction in comparison to the standard technique using Bar- clip attachment.
- Conditions
- Edentulous Alveolar Ridge, Complete Edentulism, Dental Implant, Attachments
- Trial name
- NCT06678945
- Testing
- Bar-Clip attachment, Bar- OT Equator attachment
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Recession
Aesthetic Evaluation of Two Piece 3mm Implants for Single Tooth Replacement of Maxillary Laterals and Mandibular Incisors
Aesthetic evaluation of two piece 3mm implants for single tooth replacement of maxillary laterals and mandibular incisors
- Trial name
- NCT01346345
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr.Suzanne Caudry Implant Dentistry and Periodontics
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