Clinical trials: Implants
Severe Atrophy of the Edentulous Maxilla
"Tunnel" Flap vs Trapezoidal Flap for Lateral Sinus Lift
The goal of this clinical trial is to evaluate the efficacy of the lateral sinus lift procedure using the tunnel technique flap in comparison to the traditional lateral sinus lift in partially or totally edentulous patients with…
- Trial name
- NCT06105489
- Testing
- Lateral Sinus Lift using tunnel flap technique, Lateral Sinus Lift using crestal incision flap
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Studio Dentistico Associato Sivolella
Chronic Refractory Neuropathic Pain, Ischemic Peripheral Pain
Follow-up of Post-spinal Implantable Neurostimulator PRECISION®
Assessing the long-term efficacy, complications, revision rates and final explantation of the device
- Trial name
- PRECISION (NCT02208999)
- Testing
- Neurostimulator Precision
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Cemka-Eval
Teeth Loss, Bone Loss
Maxillary Sinus Elevation With Bio-Oss or Straumann BoneCeramic
The purpose of the study was to test a clinically relevant non-inferiority of Straumann BoneCeramic treatment compared to Bio-Oss treatment 180 to 240 days after sinus grafting procedure.
- Trial name
- NCT00901121
- Testing
- Straumann BoneCeramic, Bio-Oss
- Where
- 8 sites in Italy
- Volunteers
- 48 people
- Sponsor
- Institut Straumann AG
Dental Implant Failure Nos
CATER: Comprehensive Alveolar and Tooth Esthetic Replacement
The purpose of this study is to prospectively evaluate whether including an allogeneic gum graft (PerioDerm*) during dental implant therapy improves implant health and appearance.
- Trial name
- CATER (NCT04082143)
- Testing
- Allograft mucosal enhancement with dental implant, No allograft mucosal enhancement at time of dental implant placement
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Implantable Cardioverter Defibrillator (ICD)
Patient-Reported Quality of Life in Patients With an Implantable-Cardioverter Defibrillator - A Longitudinal Observational Study
Patients at risk for life-threatening arrhythmias are eligible for the implantation of an implantable cardioverter-defibrillator (ICD), which has repeatedly shown improved survival.
- Trial name
- QoL-ICD II (NCT06654284)
- Testing
- quality of life questionnaires
- Where
- Belgium
- Volunteers
- 400 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Partial Edentulism, Tooth Disease
Assessment of Integration Success of an Implant System With a Novel Abutment Attachment Design in Early Loaded Cases
Integration success rates measured by resistance to countertorque testing will be higher for the experimental implant design than for the control implants.
- Trial name
- Comet (NCT01529814)
- Testing
- Implant with new abutment connection, Nanotite Certain Tapered implant
- Where
- Chile
- Volunteers
- 49 people
- Sponsor
- ZimVie
Edentulous Alveolar Ridge
The Impact of the Adequacy of Keratinized Mucosa on Peri-implant Tissue Health and Patient-reported Outcomes
This study aims to conduct a cross-sectional study to compare the differences in clinical indices, patient-reported outcomes, and levels of inflammatory factors in peri-implant gingival crevicular fluid between sites with…
- Trial name
- NCT07124416
- Testing
- No intervention
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Stable Angina or Acute Coronary Syndrome Considered for Percutaneous Coronary Intervention With Dyslipidemia or Hypertension
Neointimal Coverage After Implantation of Biolimus Eluting Stent With Biodegradable Polymer: Optical Coherence Tomographic Assessment According to the Treatment of Dyslipidemia and Hypertension and the Types of Implanted Drug-eluting Stents
There has been little research on neointimal coverage and malapposition after BES implantation using OCT in human coronary artery. Furthermore, specific drug may possibly influence the vascular healing after stent implantation.
- Trial name
- NCT01502904
- Testing
- Sirolimus-eluting stent, Biolimus-eluting stents, pravastatin 20mg/day after DES implantation
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Yonsei University
Bleeding, Implants
Treatment of Unfavorable Bleeding Patterns in Contraceptive Implant Users
The etonogestrel (ENG) subdermal contraceptive implant (ENG implant) is a highly effective method of preventing pregnancy, but it has bleeding side effects that make it unappealing for many women.
- Conditions
- Bleeding, Implants, Breakthrough Bleeding
- Trial name
- Tamoxifen/BTB (NCT02903121)
- Testing
- Tamoxifen, Tamoxifen (open label)
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Sudden Cardiac Death, Implantable Defibrillator User
Implantable Cardioverter Defibrillators - Improving Risk Stratification
Worldwide three million people a year die from sudden cardiac death (SCD). In most cases there is no warning and the heart is stopped by a sudden arrhythmia.
- Conditions
- Sudden Cardiac Death, Implantable Defibrillator User, Myocardial Infarction, Arrhythmias, Cardiac
- Trial name
- ICD-IRS (NCT01944514)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Multifocal Intraocular Lenses, Extended Depth of Focus
Low Add Multifocal Versus Extended Depth of Focus Intraocular Lens
The innovations in phacoemulsification surgery and advances in surgical equipment ensure a safe extraction of the crystalline lens and implantation of intraocular lenses (IOL).
- Trial name
- NCT04865016
- Testing
- Tecnis +2.75 D (ZKB00) and Tecnis Symfony (ZXR00)
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Marmara University
Disorder of Oral Mucous Membrane
Phase II Clinical Trial of Intraoral Grafting of Human Tissue Engineered Oral Mucosa
The purpose of this study is to improve the current standard of care of repairing mouth soft tissue defects.
- Trial name
- NCT01834326
- Testing
- EVPOME (autogenous ex vivo produced oral mucosa equivalent), POM (Palatal oral mucosa)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Stephen E. Feinberg
Dental Implant, Surgical Dental Prostheses
Low Intensity Pulsed Ultrasound Versus Low Level Laser Therapy Post Dental Implant
The purpose of the study is to investigate the significance difference between low intensity pulsed ultrasound (LIPUS) versus low-level laser therapy (LLLT) on osseointegration, soft tissue healing, pain pressure threshold and…
- Conditions
- Dental Implant, Surgical Dental Prostheses, Dental Implantation
- Trial name
- NCT05938868
- Testing
- Low intensity pulsed ultrasound (LIPUS), low level diode laser therapy, Standard Care
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Ahram Canadian University
Implant Complication, Complication, Postoperative
Orthopaedic Implant Removal
The necessity of orthopedic implant removal is under intense discussion and even if it is performed as an elective procedure, the risk of complications is present.
- Conditions
- Implant Complication, Complication, Postoperative, Implant Site Infection
- Trial name
- NCT03164408
- Testing
- Orthopaedic Implant Removal
- Volunteers
- 1,545 people
- Sponsor
- Universitätsmedizin Mannheim
Clinically Significant Macular Edema Due to Diabetes Mellitus
Anti-VEGF Therapy Versus Dexamethasone Implant for DME
We look at a randomized comparative study of 2 FDA approved anti-VEGF agents(aflibercept and ranibizumab) and see how they compare against the dexamethasone implant for phakic as well as pseudophakic eyes with treatment naive…
- Trial name
- NCT03999125
- Testing
- Aflibercept,, Ranibizumab Injection, Ozurdex Drug Implant Product
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Sudhalkar Eye Hospital
Hypertension
Impact of Pacing Site and AV Delay on Blood Pressure in Hypertensive Patients
The purpose of this study is to test whether the A-V sequential pacing strategy shown to effectively reduce blood pressure in a dog model of hypertension also reduces blood pressure acutely in patients with hypertension (systolic…
- Trial name
- NCT02382484
- Testing
- A dual chamber pacing system (BackBeat Medical)
- Where
- China
- Volunteers
- 19 people
- Sponsor
- BackBeat Medical Inc
Alveolar Bone Loss
Comparison of Extra-short (4 mm) Implants Used as Distal Support of a Maxillary Full-arch Fixed Dental Prosthesis vs. 10 mm Implants Installed After Sinus Floor Elevation.
Recently, 4 mm long implants with a standard diameter have been used for the restoration of the posterior edentulous mandible with favorable results.
- Trial name
- NCT03958448
- Testing
- Placement of extra short implants, maxillary sinus lift, maxillary sinus elevation, maxillary sinus augmentation, placement of standard implant
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Dental Implant
Peri-implant Soft Tissue Phenotype and Early Marginal Bone Loss After Dental Implant Placement
This prospective observational cohort study evaluated the relationship between peri-implant soft tissue characteristics and early marginal bone loss following dental implant placement.
- Trial name
- NCT07769125
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Karabuk University
Glaucoma, Corneal Damage
Corneal Endothelium After Glaucoma Surgery
The purpose of this trial is to study the change in corneal endothelial cell after glaucoma surgery, non-contact specular microscopic examination is performed for the patients who underwent glaucoma surgery; trabeculectomy and…
- Conditions
- Glaucoma, Corneal Damage, Intraocular Pressure
- Trial name
- NCT00863018
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- Chungnam National University
Complication of Cardiac Defibrillator
Health Economic Evaluation of Remote Follow up for Implantable Cardioverter Defibrillator (ICD) Patients
The purpose of the study is to define the economic value of implantable cardioverter defibrillator (ICD) remote monitoring for hospitals, third payers and patients in Italy.
- Trial name
- TARIFF (NCT01075516)
- Where
- 6 sites in Italy
- Volunteers
- 209 people
- Sponsor
- Abbott Medical Devices
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