Clinical trials: Implants
Ischemic Heart Disease, Non-ischemic Cardiomyopathy
Serial Infusions of Allogeneic Mesenchymal Stem Cells in Cardiomyopathy Patients With Left Ventricular Assist Device
A study to assess the safety and preliminary efficacy of serial intravenous dose of Allogeneic Mesenchymal Bone Marrow Cells in subjects with heart failure and implanted left ventricular assist devices.
- Trial name
- STEM-VAD (NCT03925324)
- Testing
- Human Allogeneic Mesenchymal Bone Marrow Cells (aMBMC)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Medstar Health Research Institute
Cochlear Implant
Dexamethasone Eluting Cochlear Implant: a Pivotal Study
The newly developed MED-EL Cochlear Implant Mi1250 +FLEX28 DEX (CIDEXEL) incorporates the anti-inflammatory agent dexamethasone (DEX) into the electrode array.
- Trial name
- CDEX2 (NCT06142682)
- Testing
- Cochlear Implant
- Where
- 7 sites in Germany
- Volunteers
- 59 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Alveolar Bone Loss
Biologically Oriented Alveolar Ridge Preservation (BARP) With and Without Advanced Platelet-Rich Fibrin Plus (A-PRF+)
Twenty patients were selected from the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University seeking for extraction of non-restorable maxillary premolar teeth prior to…
- Trial name
- NCT07869082
- Testing
- Socket preservation by deproteinized bovine bone graft, socket preservation by deproteinized bovine bone graft mixed with advanced PRF+
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tachycardia, Ventricular, Implantable Cardioverter Defibrillator (ICD)
PREPARE - Primary Prevention Parameters Evaluation
The purpose of this study is to test specific device programming in patients without a previous history of a life-threatening, abnormally fast heartbeat who are implanted with a Medtronic ICD (Implantable Cardioconverter…
- Conditions
- Tachycardia, Ventricular, Implantable Cardioverter Defibrillator (ICD), Fibrillation, Ventricular, Syncope
- Trial name
- NCT00279279
- Testing
- Implanted Device
- Where
- 32 sites in United States, Puerto Rico
- Volunteers
- 700 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Interphalangeal; Osteoarthritis, Proximal (Bouchard)
Results of the Tactys Implant in Proximal Interphalangeal Joint Arthroplasty
Study at middle term of the functional and radiographic results of proximal interphalangeal joint arthroplasty with the Tactys prothesis. The aim is to evaluate if the short term results are maintained in time.
- Trial name
- NCT04658459
- Testing
- Proximal Interphalangeal Joint Arthroplasty with the Tactys Prosthesis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Acute Coronary Syndrome
Vessel Wall Response of the Bio-Active-stent and Everolimus-Eluting Stent Assessed By Optical Coherence Tomography
The purpose of the trial is to evaluate the completeness of struts coverage and vessel wall response (strut malapposition, neoin-timal formation) to the bio-active-stent (BAS) versus ever-olimus-eluting stent (EES) implanted for…
- Trial name
- BASE-OCT (NCT01080859)
- Testing
- OCT
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- The Hospital District of Satakunta
Anophthalmos, Orbital Implants
Prosthetic Motility and Complications in Pegged Versus Unpegged Hydroxyapatite Orbital Implants
Pegging the hydroxyapatite for increasing prosthetic motility sometimes leads to some complications for the patient. These complications ranging from discharge, granuloma formation, exposure, implant infection to socket…
- Trial name
- NCT00371280
- Testing
- orbital implant
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Tooth Loss, Partial-edentulism
Retrospective Evaluation of a Novel Biomimetic Synthetic Bone Substitute (Creos® Syntogain)
Guided bone regeneration (GBR) is a commonly performed technique, using autogenous grafts, allografts, xenografts, or synthetic bone grafts (SBG).
- Conditions
- Tooth Loss, Partial-edentulism, Tooth Fracture, Edentulous Alveolar Ridge
- Trial name
- NCT06473545
- Where
- 2 sites in Spain
- Volunteers
- 173 people
- Sponsor
- International dentistry Research Group
Complication of Dialysis, Thrombus Due to Renal Dialysis Device, Implant, or Graft
Cerebral Microembolism During Hemodialysis
There is increasing evidence that renal replacement therapy (= continuous veno-venous hemodialysis) generates cerebral microembolism which is detectable on transcranial Doppler ultrasound.
- Conditions
- Complication of Dialysis, Thrombus Due to Renal Dialysis Device, Implant, or Graft, Cerebral Embolism
- Trial name
- NCT02021045
- Testing
- Renal hemodialysis (Fresenius 2008K, Bad Homburg, Germany)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Deafness
Perception and Equilibrium After Cochlear Implantation
The cochlear implant is an electrical hearing aid that restores the perception of surrounding sounds and speech intelligibility in profoundly deaf patients.
- Trial name
- ORIENTIMPLANT (NCT02723695)
- Testing
- Evaluation of postural performances
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Tooth Extraction, Immediate Implant Placement
Immediate Implant Placement Using Volume-Stable Collagen Matrix Combined With rhPDGF-BB
The goal of this study is to test a volume-stable collagen matrix in combination with recombinant human platelet-derived growth factor-BB, specifically in patients who have an immediate implant placement for teeth #5-#12.
- Trial name
- NCT06038695
- Testing
- Xenogeneic Volume-Stable Collagen (VCMX) graft with growth factor-BB
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- I-Ching Wang
Dental Prosthesis, Implant-Supported
A Retrospective Data Collection on NobelProcera® Zirconia Implant Bridges from 4 to 14 Units.
This is a retrospective multicenter data collection in which clinical and radiographic data on implant zirconia bridges are collected from partially or fully edentulous subjects consecutively treated with at least one 4- to…
- Trial name
- NCT06600451
- Testing
- observational study, no intervention is required
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
High-risk Corneal Transplantation, Corneal Blindess
Open-label Prospective Clinical Trial Evaluating the Safety and Efficacy of Biosynthetic CLP-PEG-MPC Corneal Implants in Patients Undergoing High-risk Deep Anterior Lamellar Keratoplasty.
This is an open-label and prospective clinical trial, in which a maximum of 5 eyes of 5 patients will receive a CLP-PEG-MPC synthetic cornea during deep anterior lamellar keratoplasty (DALK) surgery and will be followed up over…
- Conditions
- High-risk Corneal Transplantation, Corneal Blindess, Corneal Inflammation, Deep Anterior Lamellar Keratoplasty
- Trial name
- CLP-PEG-MPC (NCT05667337)
- Testing
- CLP-PEG-MPC, Human donor cornea penetrating keratoplasty
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pancreatic Cancer
Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source
Initial study to evaluate local control and the preferred method of attachment of the CivaSheet in the setting of suspected close or positive margins at the time of surgical tumor removal.
- Trial name
- NCT02843945
- Testing
- Directional Brachytherapy Source Implant
- Where
- 6 sites in United States
- Volunteers
- 80 people
- Sponsor
- CivaTech Oncology
Prosthesis Durability
Swallowing Threshold and Efficiency for Maxillary Implant Assisted Overdenture
This study aimed to compare the swallowing threshold and efficiency of conventional maxillary implant overdenture and palatless designs.
- Trial name
- NCT06622837
- Testing
- implant overdenture
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tennis Elbow, Lateral Epicondylitis
Efficacy Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis)
The investigators are testing the efficacy of a new, FDA-approved bioinductive patch in lateral epicondylitis (tennis elbow) patients.
- Trial name
- NCT03718637
- Testing
- Smith & Nephew Bioinductive Implant, Lateral Epicondylectomy, Ultrasound Imaging
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Henry Ford Health System
Spinal Cord Injury, Tetraplegia
Implanted Myoelectric Control for Restoration of Hand Function in Spinal Cord Injury
The purpose of this study is to evaluate the effectiveness of an implanted stimulator and sensor for providing hand and arm function for individuals with cervical level spinal cord injury.
- Trial name
- NCT00583804
- Testing
- IST-12
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- MetroHealth Medical Center
Healthy
Reject Analysis of Periapical Radiographs of Dental Implants.
Periapical radiographs of dental implants, acquired as part of two ongoing research projects, will be retrospectively analyzed using a newly developed image quality scoring form.
- Trial name
- RA1-2025 (NCT07876687)
- Where
- Belgium
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Ghent
Breast Implant; Complications, Quality of Life
An Analysis of Adverse Events and Satisfaction Outcomes of Women Who Underwent Primary and Secondary Breast Augmentation Using Silimed® Breast Implants With Smooth Surface
The study investigates the safety and performance of Silimed® brand smooth surface breast implants in women born with indication for primary and secondary (revision) augmentation to be followed up for 10 years.
- Conditions
- Breast Implant; Complications, Quality of Life, Satisfaction, Safety and Performance
- Trial name
- STEPS S (NCT05345821)
- Where
- Brazil
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Silimed Industria de Implantes Ltda
Osteoarthritis
Fixation of OsseoTi™ Porous Structure Versus PPS (Porous Plasma Spray) Coating on the G7™ Acetabular Component for Primary Total Hip Arthroplasty
The primary objective of this project is to investigate, using RSA, acetabular implant migration of the OsseoTi™ G7 acetabular cup in comparison to conventional PPS coated G7 acetabular cup, and compare liner wear of thinnest…
- Trial name
- NCT02316704
- Testing
- THA with G7 PPS coted acetabular component, THA with G7 OsseoTi coted acetabular component
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 98 people
- Sponsor
- Hvidovre University Hospital
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