Clinical trials: Implants
Cochlear Implant, Cochlear Implant Users
Patient-Oriented Research to Optimize Cochlear Implant Outcomes
The rationale is that only through understanding how individual Cochlear Implant (CI) patients respond to interventions investigators further develop precision-medicine approaches to optimize outcomes.
- Conditions
- Cochlear Implant, Cochlear Implant Users, Cochlear Implant Recipients, Cochlear Implant Listeners
- Trial name
- NCT07678879
- Testing
- AC Group, CA group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Guided Immediate Implant Placement
Silicate β-TCP vs Extended Sticky Bone for Peri-Implant Jumping Gap in Guided Immediate Implants: RCT
This randomized clinical trial compares three peri-implant jumping gap management approaches following fully guided immediate implant placement in the maxillary esthetic zone.
- Conditions
- Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Guided Immediate Implant Placement, Bone Grafting, Customized Healing Abutment
- Trial name
- JUMP-ESTHETIC (NCT07700706)
- Testing
- No Grafting, Silicate-Added β-TCP Putty, Extended Sticky Bone
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Immediate Dental Implant Placement
Influence of Provisional Restoration Type on Outcomes of Immediate Implant Placement and Loading
A randomized clinical trial comparing 3D-printed resin and CAD/CAM-milled PMMA provisional restorations used for immediate loading of fully digitally guided immediate implants.
- Conditions
- Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Immediate Dental Implant Placement, Immediate Loading, Provisional Restoration
- Trial name
- PRODIGI (NCT07700771)
- Testing
- 3D-Printed Resin Provisional Crown, CAD/CAM-Milled PMMA Provisional Crown
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Breast Cancer, Implant Breast Reconstruction
Hypofractionated vs. Conventionally Fractionated Postmastectomy Radiotherapy After Implant-Based Reconstruction
This is a prospective, randomized controlled, non-inferiority clinical trial designed to compare the outcomes of hypofractionated radiotherapy versus conventionally fractionated radiotherapy following mastectomy and implant-based…
- Trial name
- NCT07835139
- Testing
- ConvRT, HypoRT
- Where
- China
- Volunteers
- 534 people
- Sponsor
- Fudan University
Peri-Implant Mucositis
Short Versus Standard Dental Implants: Clinical and Biomarker Outcomes
This study compares two types of dental implants, short implants (6 millimeters or less in length) and standard implants (longer than 8 millimeters), to evaluate their effect on the health of the gum and bone tissue surrounding…
- Trial name
- NCT07828067
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Inonu University
Immediate Implant
Immediate Implant Placement Using Immediate Dentoalveolar Restoration Versus Ice Cream Cone Technique With Labial Plate Dehiscence
: Evaluation of Soft and Hard Tissue Changes following Immediate Implant using Immediate Dentoalveolar Restoration Versus Ice Cream Cone technique for management of Cases With Labial Plate Dehiscence
- Trial name
- NCT05946954
- Testing
- Immediate Dentoalveolar Restoration, Ice cream cone technique
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Aya Sharaf
Peri-Implant Health, Peri Implant Mucositis
Impact of Smoking on Immune Responses in Peri-implant Health and Disease
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases…
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis
- Trial name
- NCT07750171
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cochlear Implant, Severe to Very Severe Sensorineural Hearing Loss
Epidemiological Survey on the Current Status of Cochlear Implantation in China
Cochlear implantation is an effective intervention for patients with severe to very severe sensorineural hearing loss. By the beginning of 2026, the total number of cochlear implants in China was about 180000.
- Trial name
- NCT07821281
- Testing
- Cochlear Implant
- Volunteers
- 180,000 people
- Sponsor
- Chinese PLA General Hospital
Jaw, Edentulous, Edentulism, Complete
Tri-Lobe vs. Hexagonal Connections in Immediately Loaded Mandibular Overdentures
Objective: Compare changes in crestal bone height and peri-implant bone density using cone-beam computed tomography (CBCT) at baseline, 6 months, and 12 months post-placement.
- Conditions
- Jaw, Edentulous, Edentulism, Complete, Peri-implant Bone Loss
- Trial name
- NCT07824219
- Testing
- ReActive Implant System (Internal Tri-Lobe Platform), Legacy II Implant System (Internal Hexagonal Platform)
- Where
- United Arab Emirates
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Immediate Implant Placement in Mandibular Molar Extraction Sockets
3D-Printed PLA Guide Versus Resin Guide in Mandibular Molar Implant Placement
This randomized clinical trial compares two tooth-supported computer-guided surgical guide systems for immediate implant placement in mandibular molar extraction sockets: a patient-specific 3D-printed PLA guide system and a…
- Trial name
- CGIIPMM-PLA-MR (NCT07826039)
- Testing
- immediate implant placement using PLA guide, Immediate implant placement using Modified resin guide.
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mohamed Esmail Ahmed Hassan
Cochlear Implants
Middle East MED-EL Observatory Study
In the field of cochlear implant research, there are only few data on long-term observational studies available to gain knowledge on clinical effectiveness.
- Trial name
- MEMOS (NCT03882229)
- Testing
- MED-EL CI systems
- Where
- 3 sites in Egypt, Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Implant Stability
Evaluation of Two Mini-implant Diameters in the Infra-zygomatic Crest Region.
The goal of this clinical trials is to compare two diameters, 1.6 and 2 mm, of mini implants both are 12 mm length placed in the infrazygomatic crest region.
- Trial name
- TADs (NCT07337538)
- Testing
- insersion of two diameters of mini implant.
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Peri-implant Soft Tissue Deficiency, Insufficient Peri-implant Keratinized Tissue
CTG Versus Collagen Matrix for Peri-Implant Soft Tissue Augmentation
This randomized controlled trial compares two techniques for peri-implant soft tissue augmentation in the mandibular molar region: an autogenous connective tissue graft (CTG) and a collagen matrix.
- Trial name
- NCT07371481
- Testing
- Collagen Matrix, Connective Tissue Graft
- Where
- Vietnam
- Volunteers
- 46 people
- Sponsor
- Hanoi Medical University
Alveolar Bone Loss in Mandible, Guided Bone Regeneration
Clinical and Patient-reported Outcomes of Guided Versus Freehand Harvesting Of Positioning of Autogenous Bone Shells
When people lose teeth or have gum disease, the jawbone can shrink over time. This shrinkage makes it difficult for dentists to place dental implants because implants need a strong and stable base of bone.
- Conditions
- Alveolar Bone Loss in Mandible, Guided Bone Regeneration, Dental Implant
- Trial name
- guided (NCT07381608)
- Testing
- Free hand shell technique, Guided shell technique
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shalash Dental education
Peri-Implant Marginal Bone Loss, Dental Implantation
CBCT Assessment of Marginal Bone Changes With Ozone Therapy
This study examined whether adding local gaseous ozone to standard dental implant treatment could reduce early bone loss around implants. Fifty adults requiring matched implants on opposite sides of the same jaw participated.
- Trial name
- ozone-ımplant (NCT07687641)
- Testing
- Gaseous Ozone Application, Conventional Implant Placement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Teeth Absent, Teeth Missing
Multicenter Clinical Study on the Efficacy and Esthetic Outcomes of Immediate Implant Placement Using the Socket-Shield Technique Versus Conventional Immediate Implantation in the Anterior Maxillary Esthetic Zone
This study plans to enroll no fewer than 48 adult patients who have non-restorable maxillary anterior teeth due to trauma or dental diseases and are candidates for immediate implant placement, meeting the inclusion and exclusion…
- Conditions
- Teeth Absent, Teeth Missing, Dental Implant
- Trial name
- NCT07822685
- Testing
- the Socket Shield Technique (SST) immediate implant placement, Conventional immediate implant placement
- Volunteers
- 48 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Implant Complication
Immediate Versus Delayed Loading of Maxillary Overdenture Implants
The purpose of the study is to evaluate the radiographic, clinical and patient-centered outcomes of implant-retained immediately-loaded maxillary complete dentures in comparison to delayed loading approach by primarily evaluating…
- Trial name
- NCT06038487
- Testing
- Immediate loading of maxillary implant overdenture, Delayed loading of maxillary implant overdenture
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
IMPLANTATION, Dental Implant
Flapless Mini-incision Implant Surgery
evaluate the clinical efficacy of the flapless mini-incision method compared to conventional flap and flapless punch methods
- Conditions
- IMPLANTATION, Dental Implant, Dental Implant Placement, Peri-Implant Tissues
- Trial name
- NCT07008079
- Testing
- Flapless punch, Flapless mini-incision, Conventional flap
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Alaa Emara
Immediate Dental Implant, Socket Sealing
Socket Sealing Abutment With Immediate Implant
This study aimed to evaluate bone and soft tissue changes clinically and radio-graphically after using socket sealing abutment with or without bone graft material.
- Conditions
- Immediate Dental Implant, Socket Sealing, Molar Teeth
- Trial name
- NCT07748494
- Testing
- Immediate Molar Implant Placement with Grafting Material, Immediate Molar Implant Placement without Grafting Material
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Edentulism; Implant-retained Mandibular Overdentures
Effect of Adding Silicon Dioxide (SiO₂) Nanoparticles to a Printable Acrylic Resin Denture Base
This clinical study evaluated whether adding a small amount (0.5 wt%) of silicon dioxide (SiO₂) nanoparticles to a 3D-printable acrylic denture material could improve the clinical performance of implant-retained mandibular…
- Trial name
- NCT07817420
- Testing
- Standard 3D-printed acrylic resin denture base, SIO2 nanoparticle-modified 3D-printed acrylic resin denture base
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University