Clinical trials: Implants, open to volunteers
Breast Cancer, Implant Breast Reconstruction
Hypofractionated vs. Conventionally Fractionated Postmastectomy Radiotherapy After Implant-Based Reconstruction
This is a prospective, randomized controlled, non-inferiority clinical trial designed to compare the outcomes of hypofractionated radiotherapy versus conventionally fractionated radiotherapy following mastectomy and implant-based…
- Trial name
- NCT07835139
- Testing
- ConvRT, HypoRT
- Where
- China
- Volunteers
- 534 people
- Sponsor
- Fudan University
Distal Radius Fractures, Degenerative Lumbar Spondylolisthesis
Long-term Safety Trial with NVDX3
An study evaluating the long-term safety of all patients previously treated with NVDX3.
- Trial name
- X3LTFU (NCT06532253)
- Testing
- NVDX3
- Where
- Luxembourg
- Volunteers
- 15 people
- Sponsor
- Novadip Biosciences
Osteoarthritis, Hip, Inflammatory Arthritis
The ACTIVE Trial: A Prospective Randomised Control Trial Of The H1 Implant Versus Total Hip Replacement
The goal of this randomised controlled trial is to compare the success of two types of hip replacement in patients with hip arthritis.
- Trial name
- ACTIVE (NCT06162195)
- Testing
- The H1 Implant, Cementless total hip replacement
- Where
- 3 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Embody Orthopaedic Limited
Cochlear Hearing Loss
Vocal Emotion Communication With Cochlear Implants
Patients with hearing loss who use cochlear implants (CIs) show significant deficits and strong unexplained intersubject variability in their perception and production of spoken emotions in speech.
- Trial name
- NCT05486637
- Testing
- Perception of acoustic cues to emotion, Production of acoustic cues to emotion
- Where
- 4 sites in United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Dental Implant, Bone Resorption
Randomized Clinical Study Comparing Two Guided Surgery Techniques for Free-end Implant Placement
This is a randomized multicenter clinical study that compares two static guided surgery techniques in free-end partial edentulism.
- Trial name
- NCT06764654
- Testing
- Dental implant placement
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Aula Dental Avanzada
Peri Implant Mucositis, Dental Implant Rehabilitation
Home-Use Dual-Light Antibacterial Photodynamic Therapy for Peri-Implant Mucositis in Full-Arch Implant Prostheses
The goal of this clinical trial is to learn whether a home-use light device helps control gum inflammation around dental implants in adults who have a full set of fixed teeth attached to implants.
- Conditions
- Peri Implant Mucositis, Dental Implant Rehabilitation, Prosthesis and Implant Dentistry, Implant Supported Prosthesis
- Trial name
- NCT07763431
- Testing
- Dual-light antibacterial photodynamic therapy, Supportive peri-implant care
- Where
- Vietnam
- Volunteers
- 24 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Partial-edentulism
Extra-short vs. Non-extra-short Dental Implants Splinted on the Same Prosthesis
The main aim of this prospective study is to analyze the survival rate of short-length implants (<6.5 mm) in subjects with partial edentulism. Non-short length implant will be used as control arm.
- Trial name
- NCT04927819
- Testing
- BTI Implant
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Fundación Eduardo Anitua
Dental Implant
Optimizing Alveolar Ridge Expansion
The goal of this clinical trial is to compare two surgical techniques-Magneto-Dynamic Ridge Splitting and Versah Osseodensification-for expanding narrow alveolar ridges in adults requiring dental implant placement.
- Trial name
- NCT07066930
- Testing
- Magneto-Dynamic Ridge Expansion, Osseodensification with Versah Drills
- Where
- Iraq
- Volunteers
- 40 people
- Sponsor
- Hawler Medical University
Deafness Caused by High Grade Microtia or Ear Atresia
OSIA System Bilateral Implantation Efficacy Evaluation in Children With Ear Aplasia
The aim of this study is to compare speech perception in noise with one activated Osia (unilateral) versus two activated Osia (bilateral), in children with high grade microtia/ear atresia fitted with bilateral Osia implants.
- Trial name
- APLOSIA (NCT07358728)
- Testing
- Audiological tests, Speech, Spatial and Qualities of Hearing Scale
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ridge Preservation, Allografts
Comparison of Two Types of Bone Grafts in Patients Who Need One of Their Front Teeth Removed and Replaced With an Implant
The purpose of this study is to compare two different bone graft materials (freeze-dried bone allograft, FDBA and collagen-enriched bovine xenograft, CEBX) that are routinely used for preserving the remaining bone after…
- Conditions
- Ridge Preservation, Allografts, Extraction, Tooth, Xenograft
- Trial name
- FDBA or CEBX (NCT06722482)
- Testing
- FDBA, CEBX
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Rochester
Peri-Implantitis
Intaglio Surface of Full-arch Implant Supported Prosthesis
The purpose of the study is to determine if there is an association between the intaglio shape of full-arch implant-supported prosthesis and marginal bone level around implants.
- Trial name
- NCT06636097
- Testing
- Full arch
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Dental Implant
Immediate Versus Conventional Loading of Early Placed Dental Implant Supporting Single Crowns
This study focuses on examining the efficacy and clinical performance of immediate loading of early placed single implants. The aim of the randomized controlled trial is to compare between two loading protocols (immediate versus…
- Trial name
- NCT06693297
- Testing
- Immediate loading of early placed implants, Conventional loading of early placed implants
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Partial Edentulism, Dental Implant
Immediate vs Conventional Loading With Different Crown Materials on Immediately Placed Single Implants
This randomized controlled trial compares immediate and conventional loading of single implants placed immediately into fresh extraction sockets in the upper front and premolar region.
- Conditions
- Partial Edentulism, Dental Implant, Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement
- Trial name
- NCT07882095
- Testing
- Conventional loading, Monolithic zirconia crown, Permanent 3D-printed PMMA crown
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Peri-Implant Health, Peri-Implant Tissues
Volumetric Analysis of Peri-Implant Soft Tissue Changes Between Polyethereketone(PEEK) Anatomic Healing Abutments and Standard Healing Abutments in Posterior Single Implant Restorations
This prospective randomized clinical trial will evaluate the clinical outcomes of the implant crown fabricated with standard scan body (control) and polyetheretherketone (PEEK) anatomic healing abutment (test).
- Conditions
- Peri-Implant Health, Peri-Implant Tissues, Soft Tissue Augmentation at Dental Implants
- Trial name
- anatomic (NCT07624331)
- Testing
- AHA PEEK, standard healing abutment
- Where
- Malaysia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- DR NUR HAFIZAH KAMAR AFFENDI
Breast Cancer Female, Breast Cancer Prevent
First-in-human, Study of MATTISSE® Tissue Engineering Chamber in Adult Female Patients Undergoing Breast Reconstruction After Mastectomy for Cancer
This study is a first in human, two-stage single arm non-comparative study of safety and performance. The aim of the study is to asses the safety and the clinical performance of a new device : the MATTISSE tissu engineering…
- Conditions
- Breast Cancer Female, Breast Cancer Prevent, Breast Reconstruction
- Trial name
- TIDE (NCT05460780)
- Testing
- MATTISSE TEC
- Where
- 3 sites in France, Georgia
- Volunteers
- 50 people
- Sponsor
- Quanta Medical
Immediate Dental Implant Placement
Effect of Theravex Tissue Care on Implant Stability
The aim of this randomized clinical trial is to evaluate the clinical and radiographic outcomes of using Bone Bioactive Liquid (Theravex) compared to Xenograft and a combination therapy (Theravex + Xenograft) during immediate…
- Trial name
- NCT07707388
- Testing
- Bone Bioactive Liquid, Bovine-derived Xenograft, Immediate Implant Placement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Embolic Stroke of Undetermined Source
AI-Based Prediction of Atrial Fibrillation in ESUS Patients With ICM
This study investigates patients with Embolic Stroke of Undetermined Source (ESUS) who have received an Implantable Cardiac Monitor (ICM).
- Trial name
- SMART-ESUS (NCT07347691)
- Where
- 5 sites in South Korea
- Volunteers
- 92 people
- Sponsor
- Inha University Hospital
Edentulous Mandible, Implant-Supported Overdentures
Mandibular Implant Overdenture With OT Cap Bar vs Bar Attachment
This clinical study is being conducted at Cairo University to evaluate two different types of attachments used with implant-supported dentures in the mandible.
- Trial name
- NCT07067190
- Testing
- Conventional Bar Attachment, Bar with OT Cap Attachment
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Maisa Mohamed Farid Shaaban
Dental Implant, Dental Implant-Abutment Design
SOI Immediately vs Delayed
The aim of this randomized controlled trial is to compare the clinical and radiographic of immediately loaded, immediate (post-extractive, test group) versus delayed (control group) implants with new SOI surface
- Trial name
- NCT06286579
- Testing
- Immediately implant placement, Delayed
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Dental Implant
Immediate vs Conventional Loading for Early Implant Placement
The goal of this study is to assess clinical, radiological and patient centred outcomes of immediate and conventional implant loading protocols, and to compare clinical outcomes of these two different loading protocols (immediate…
- Trial name
- NCT06526351
- Testing
- Early implant placement with immediate provisional restoration, Early implant placement with delayed loading
- Where
- Serbia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
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