Clinical trials: Implementation
Nurse Practitioners, Implementation Research
Role Development, Implementation and Evaluation of Nurse Practitioners
Hospitals face new challenges in providing sustainable high quality care as the prevalence of chronic conditions, multimorbidity and the complexity of care increases.
- Conditions
- Nurse Practitioners, Implementation Research, Quality of Care
- Trial name
- NUPRA-DI (NCT05520203)
- Testing
- Care provided by the Nurse Practitioner
- Where
- 2 sites in Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Prediabetes, Diabetes Prevention
Optimizing Implementation of the Intensive Diabetes Prevention Program
The goal of this clinical trial is to explore the effectiveness and implementation outcomes of the optimized Intensive Diabetes Prevention Program (IDPP) in District Health Centres.
- Conditions
- Prediabetes, Diabetes Prevention, Implementation Science
- Trial name
- NCT07412912
- Testing
- Standard IDPP, Optimized IDPP
- Volunteers
- 170 people
- Sponsor
- The Hong Kong Polytechnic University
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans
Women Veterans are the fastest growing segment of VA users. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that they will want and be able…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Smoking
- Trial name
- EMPOWER (NCT05050266)
- Testing
- EBQI, REP
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Program Effectiveness, Program Implementation
Implementation Study With Embedded RCT of a Digital System of Parenting Support Within Government Services in South Africa
ParentText, a WhatsApp-based parenting support programme, is designed as a universal intervention to improve parent-child relationships (module 1) and promote child safety (module 2).
- Conditions
- Program Effectiveness, Program Implementation, Parent Child Relationship, Caregiver Child Relationship
- Trial name
- SWIFT (NCT07814261)
- Testing
- Module 1 - Improve My Relationship with My Teen/Child, Module 2 - Keep My Child/Teen Safe and Healthy
- Where
- South Africa
- Volunteers
- 4,961 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Delirium, Neurocognitive Disorders
Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders
The goal of this clinical trial is to compare the Hospital Elder Life Program (HELP) with a family-augmented version of HELP (FAM-HELP), that includes family members and care partners, for the prevention of delirium in older…
- Conditions
- Delirium, Neurocognitive Disorders, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- ENHANCE (NCT05929703)
- Testing
- HELP, FAM-HELP
- Where
- 7 sites in United States
- Volunteers
- 1,900 people
- Sponsor
- University of Michigan
Population Genomic Screening Implementation Best Practices
Facilitating the Implementation of Population-wide Genomic Screening
This is a multi-site hybrid implementation-effectiveness trial that uses a stepped-wedge cluster randomized design to evaluate the impact of the FOCUS toolkit, a multicomponent implementation guide, on improving the…
- Trial name
- FOCUS (NCT07806643)
- Testing
- FOCUS Toolkit Training
- Where
- 7 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Food Choice, Implementation Science
Healthy Options At Pantries (HOAP) Study
This study will evaluate a digital nudge intervention, Healthy Options At Pantries (HOAP), in the online food pantries of three large charitable food organizations.
- Conditions
- Food Choice, Implementation Science, Food Insecurity, Diet, Healthy
- Trial name
- HOAP (NCT07729436)
- Testing
- Behavioral economics-based Healthy Options At Pantries (HOAP) digital nudge intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Implementation Science, Engagement, Patient
Parents Helping Parents for Youth Vaping Cessation
The goal of this randomized controlled study is to test if this new intervention works to help adolescents quit vaping. A key feature of the program is the use of peer support for parents, delivered by trained parent coaches.
- Conditions
- Implementation Science, Engagement, Patient, E Cigarette Use, Peer Support
- Trial name
- PhP-VX (NCT07207850)
- Testing
- Parents Helping Parents program
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Nebraska
Nurse-Patient Relations, Implementation Research
Nurses in the Lead - Nursing Leadership and Autonomy in Function Focused Care in Hospital
The goal of this prospective before-after study (observational) is to implement Function Focused Care in Hospital (FFCiH), paying specific attention to the role of nurses and how they can take the leadership and autonomy in the…
- Conditions
- Nurse-Patient Relations, Implementation Research, Physical Inactivity, Physical Activities
- Trial name
- NCT06878820
- Testing
- Function Focused Care
- Where
- 3 sites in Netherlands
- Volunteers
- 425 people
- Sponsor
- Leiden University Medical Center
Implementation Science, Type 1 Diabetes in Adolescence
Pilot Implementation Trial of Implementation Toolkits for Diabetes Coaching
The goal of this study is to learn if toolkits of implementation strategies (e.g., provider and staff education, clear plan for how to refer and bill) help pediatric type 1 diabetes medical and psychology providers deliver a…
- Conditions
- Implementation Science, Type 1 Diabetes in Adolescence, Implementation Strategies
- Trial name
- NCT07766811
- Testing
- Base Implementation Toolkit (BIT), BIT-Enhanced, BIT-Sustainment
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Osteoarthritis (OA), Osteoarthritis (OA) of the Hip
Evaluation of Choose to Move Replacement Ready (CTM-RR)
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Total Knee Anthroplasty
- Trial name
- CTM-RR (NCT07696650)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 210 people
- Sponsor
- University of British Columbia
Pediatric Obesity, Implementation
Parks & Pediatrics Fit Together
The proposed project will test an implementation strategy (the "TrailGuide") for delivering an existing model of pediatric obesity treatment ("Fit Together") that has demonstrated ability to meet published recommendations for…
- Trial name
- NCT05455190
- Testing
- Fit Together, Educational materials
- Where
- 3 sites in United States
- Volunteers
- 209 people
- Sponsor
- Duke University
Implementation Science, Women Health
REmote Virtual Inspiration: Vitality and Energy
REVIVE is a randomized controlled trial designed to evaluate the effects of a remotely delivered seated Tai Chi/Qigong (TCQ) intervention on cardiometabolic health, stress, sleep, and psychological well-being among women with…
- Conditions
- Implementation Science, Women Health, Disability Physical, Meditation
- Trial name
- REVIVE (NCT07675681)
- Testing
- Accesible Tai Chi/Qigong (TCQ), Health Education Videos (HEV)
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Arizona State University
Implementation Science, Heart Transplant
Seeking Objectivity in Allocation of Advanced Heart Failure (SOCIAL HF) Therapies Trial
The primary goal of this study is to assess real-world effectiveness and implementation of an evidence-based multi-component strategy to reduce disparities in the allocation rate of advanced heart failure therapies, heart…
- Conditions
- Implementation Science, Heart Transplant, Decision Making
- Trial name
- SOCIAL HF (NCT05390411)
- Testing
- SOCIAL HF
- Where
- United States
- Volunteers
- 1,463 people, healthy volunteers welcome
- Sponsor
- Indiana University
Parenting, Prevention
Hybrid Delivery to Increase Access and Sustainability: Evaluating ezParent Implementation
The goal of this study is to evaluate the effects of the hybrid ezParent program (e.g., web-based training program plus synchronous group sessions) on parent and child outcomes in a community setting serving parents of children…
- Conditions
- Parenting, Prevention, Program Implementation, Early Childhood
- Trial name
- ezParent FT (NCT07417930)
- Testing
- ezParent
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Implementation Science, Informed Consent
Implementing a Novel Consent Process for Biospecimen Research After Newborn Screening
The purpose of this study is to implement an electronic consent education process for the retention and research use of residual dried bloodspots at four hospitals in Michigan and assess the impact of the new education, both on…
- Conditions
- Implementation Science, Informed Consent, Neonatal Screening
- Trial name
- MICI (NCT06192511)
- Testing
- Educational Website and Video
- Where
- 2 sites in United States
- Volunteers
- 5,980 people, healthy volunteers welcome
- Sponsor
- Erin Rothwell
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Palliative Therapy, Implementation Science
Clinical Surveillance Tool to Screen for Unmet Palliative Needs Among Patients in the Final Year of Life
One of the most important obstacles to improving end-of-life care is the inability of clinicians to reliably identify those who are approaching the end-of-life.
- Conditions
- Palliative Therapy, Implementation Science, Screening, Terminal Care
- Trial name
- HOMR (NCT04171830)
- Testing
- modified Hospital One-year Mortality Risk (mHOMR)
- Where
- 13 sites in Canada
- Volunteers
- 3,536 people
- Sponsor
- Ottawa Hospital Research Institute
Asthma in Children, Implementation
Y of Central Maryland Head Start Asthma Implementation
Despite a strong evidence-base for the efficacy of multilevel programs in reducing asthma symptoms among low-income preschool minority children, gaps remain in our understanding of how to best translate and scale up these…
- Conditions
- Asthma in Children, Implementation, Preschool Children
- Trial name
- NCT05004714
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Johns Hopkins University
Substance Use Disorder, Opioid Use Disorder
Testing the CrOss Systems Technical Assistance for Retaining Staff (COSTARS) Model for Improving Staff Retention Among Child Welfare Workers and Peer Supporters, and Implementation of Evidence Based Interventions.
The goal of this study is to test whether the CrOss System Technical Assistance for Retaining Staff (COSTARS) supervision leadership institute can promote workforce stability and improved implementation outcomes within the Ohio…
- Conditions
- Substance Use Disorder, Opioid Use Disorder, Child Maltreatment, Implementation
- Trial name
- COSTARS (NCT07439783)
- Testing
- COSTARS, Implementation As Usual
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Alicia Bunger