Clinical trials: Implementation, open to volunteers
Indoor Air Quality
DIY Indoor Air Cleaner Study in Rural and Urban Communities in Colorado
Elevated levels of particulate matter (PM) are associated with adverse health outcomes such as asthma exacerbations, cardiovascular issues, and respiratory diseases.
- Trial name
- NCT07815652
- Testing
- DIY Air Cleaner and Breathe Clean Video
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Social Determinants of Health (SDOH)
The Development, Implementation, and Evaluation of a Social Engagement Support System
The goal of this clinical trial is to determine if artificial intelligence and machine learning (AI/ML) models can help address social needs in Medicaid enrollees.
- Trial name
- NCT06913049
- Testing
- Social Engagement Support System
- Where
- United States
- Volunteers
- 249,660 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore County
Communication Disabilities
Implementation of Communication Disability Collection and Accommodations in Primary Care Settings
This multi-methods-multi-site study aims to adapt and evaluate the effects of an implementation support package of strategies to assist primary care clinics in documenting patients' communication disability (CD) and accommodation…
- Trial name
- DECA (NCT07656584)
- Testing
- Implementation Support Package
- Where
- 5 sites in United States
- Volunteers
- 126,870 people
- Sponsor
- NYU Langone Health
Cancer
Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)
The purpose of the study is to understand patient interest in telehealth and digital tools for pre-test genetic education and/or disclosure of genetic test results.
- Trial name
- eREACH3 (NCT07471958)
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Infusions, Intravenous, Implementation Science
Validation of the Effectiveness of the CFIR - ERIC Matching Tool in Implementation Research
The goal of this implementation study is to learn if the CFIR-ERIC matching tool is effective indeveloping implementation strategies for pediatric nurse.
- Trial name
- NCT07184489
- Testing
- implementation strategies
- Where
- China
- Volunteers
- 394 people
- Sponsor
- Children's Hospital of Fudan University
Preeclampsia (PE)
Prevention of Preeclampsia in Denmark: A National Implementation Study
The goal of this clinical study is to learn if a new first-trimester screening program can better find pregnant women who are at high risk of developing preeclampsia and help prevent the condition with early treatment.
- Trial name
- PREPRED (NCT07485140)
- Testing
- First trimester screening for preeclampsia
- Where
- 3 sites in Denmark
- Volunteers
- 80,000 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
Suspected Neutropenic Fever, Confirmed Neutropenic Fever
Diagnostic Accuracy, Clinical Utility and Implementation of Point-of-Care Absolute Neutrophil Count in Suspected Neutropenic Fever (DUCATIS) - Diagnostic Accuracy (S1)
Study 1 (S1). In a range of adult patients with sNF and controls, there is no significant difference between the POC-ANC and laboratory analyser. The diagnostic study will be performed 24 hours a day.
- Conditions
- Suspected Neutropenic Fever, Confirmed Neutropenic Fever, Severe Neutropenic Fever, Neutropenic Fever
- Trial name
- DUCATIS - S1 (NCT07901660)
- Testing
- Hemocue® WBC DIFF system
- Where
- Hong Kong
- Volunteers
- 317 people
- Sponsor
- The University of Hong Kong
HFrEF - Heart Failure With Reduced Ejection Fraction, Guideline Adherence
Guideline Implementation and Quality of Care Evaluation in Patients With Heart Failure and Reduced Ejection Fraction (HFrEF)
The IMPLEMENT HF study is part of the national heart failure quality of care registry (evaluation of given health care). Within the HF registry, the investigators will investigate whether mirror information on the actual 4…
- Trial name
- IMPLEMENT HF (NCT07702760)
- Where
- Netherlands
- Volunteers
- 1,500 people
- Sponsor
- Jasper Brugts MD PhD
Parenting Intervention, Stress
Resilience Through Interventions for Successful Early Outcomes
Purpose: The purpose of this research is to determine the effects of Attachment and Biobehavioral Catch-up (ABC), an evidence-based parenting program, on stress biomarkers in children.
- Conditions
- Parenting Intervention, Stress, Caregiver Child Relationship, Child Behavior Problem
- Trial name
- RISE (NCT06669624)
- Testing
- Attachment and Biobehavioral Catch-up (ABC), Waitlist with 4-month delay, then ABC
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteoarthritis, Osteoarthritis (OA) of the Knee
Feasibility of Choose to Move Replacement Ready
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis, Hip, Total Knee Arthroplasty; Total Hip Arthroplasty
- Trial name
- CTM-RR (NCT07069179)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Physical Activity, Exercise Training
Home-based Exercise and Physical Activity Intervention After Kidney Transplantation: Impact of Exercise Intensity
This multicentre two-phased RCT aims to evaluate implementation potential, cost-effectiveness, effectiveness, and the role of exercise intensity of a home-based exercise and physical activity intervention to improve de novo…
- Conditions
- Physical Activity, Exercise Training, Kidney Transplantation, Physical Fitness
- Trial name
- PHOENIX-Kidney (NCT06260579)
- Testing
- Exercise/physical activity
- Where
- 2 sites in Belgium
- Volunteers
- 147 people
- Sponsor
- KU Leuven
Aging, Hospitalization
Personalized Exercises Program Prescription to Prevent Functional Decline Throughout Older Adults Hospitalization
Bed rest related to hospitalization contributes to the physical decline in capacities of the elderly, the loss of autonomy accelerated in post-hospitalization and the prevalence of the iatrogenic functional decline is about 20 to…
- Trial name
- NCT04078334
- Testing
- MATCH, PATH, PATH 2.0
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Université du Québec a Montréal
Knowledge, Attitudes, Practice
MAP for Coaches: Translating Sports Injury Prevention Knowledge to Youth Sport Coaches
The goal of this clinical trial is to test the effectiveness of the MAP for Coaches, a web-based Musculoskeletal Athletic injury Prevention training course, in youth sport coaches.
- Trial name
- MAP (NCT05718063)
- Testing
- MAP for Coaches - Complete Course, Map for Coaches - Overview
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Cancer, Survivorship
Study of a Support Program for Quality of Life in Chinese Cancer Patients and Survivors
The purpose of this study is to evaluate different combinations of cancer education sessions, counseling sessions, and peer support meetings developed for Chinese cancer patients and survivors.
- Trial name
- NCT07454330
- Testing
- Cancer Education, Meaning-Centered Counseling, Peer Support
- Where
- 7 sites in United States
- Volunteers
- 64 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Low Back Pain
A Multilevel Intervention for Low Back Pain Management in Primary Care
Low back pain is the leading cause of disability worldwide and one of the main reasons for consulting in primary care. This project aims to improve the management of people with low back pain in primary care through an innovative…
- Trial name
- PRIME Back (NCT07137065)
- Testing
- PRImary care MultilEvel intervention for low back pain (PRIME), Usual Care
- Where
- 2 sites in Switzerland
- Volunteers
- 500 people
- Sponsor
- Guillaume Christe
Urinary Incontinence, Anal Incontinence
Pelvic Floor Muscle Training During Pregnancy
The project seeks to investigate effectiveness of PFMT during pregnancy.
- Conditions
- Urinary Incontinence, Anal Incontinence, Pelvic Organ Prolapse, Sexual Dysfunction
- Trial name
- NCT07104292
- Testing
- PFMT, Standard care
- Where
- Denmark
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Pain, Irritability
Implementation of the Pain and Irritability of Unknown Origin (PIUO) Pathway in Community Pediatric Practices
The Pain and Irritability of Unknown Origin (PIUO) Pathway is a clinical pathway that was developed to evaluate and manage unexplained pain and irritability for children with severe neurological impairments (SNI) who cannot…
- Conditions
- Pain, Irritability, Neuropathic Pain
- Trial name
- NCT06869928
- Testing
- PIUO Pathway
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Anxiety, Depression in Adolescence
Co-designing Adaptations of a Digital Mental Health Intervention (Wysa) for Adolescent Girls With Anxiety or Depression in Rural India
The goal of this study is to culturally and contextually adapt Wysa, an evidence-based AI-powered digital mental health intervention (DMHI), for adolescent girls (ages 13-18) with symptoms of anxiety and/or depression in rural…
- Conditions
- Anxiety, Depression in Adolescence, Anxiety Disorder of Adolescence
- Trial name
- NCT07595029
- Testing
- Digital psychosocial tool
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Wysa
Headache, Migraine
Adolescent Lifestyle Medicine Headache Study
The goal of this pilot clinical trial is to assess the implementation of a 7-week Lifestyle Medicine intervention for adolescents with headache.
- Trial name
- NCT07373275
- Testing
- Lifestyle Medicine Group Medical Visits
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- MaineHealth
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Consumption
Pilot of an Intervention to Reduce Alcohol Use and Improve ART Adherence Among Men Living With HIV With Pregnant Partners in Uganda.
Hazardous alcohol use, which is common among men in Uganda, is a primary driver of both HIV risk and intimate partner violence (IPV) in this setting.
- Trial name
- Kisoboka Amaka (NCT06900634)
- Testing
- Kisoboka Amaka, Screening and Referral
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- San Diego State University
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