Clinical trials: Implementation Science
Oral Disease, Dental Caries
Implementing a Participatory, Multi-level Intervention to Improve Asian American Health Study
This feasibility and acceptability study will be conducted at 3 community outreach centers serving an urban, low-income Chinese population.
- Trial name
- NCT03438045
- Testing
- Partnered intervention
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
HIV Infections
A Study Evaluating Implementation Strategies for the Delivery of Cabotegravir in Low and High-Volume PrEP Site in the United States
This is a two-arm study evaluating the impact of two implementation strategy conditions, dynamic implementation and routine implementation on the feasibility of delivering of Cabotegravir PrEP in low and high-volume PrEP sites in…
- Trial name
- PILLAR (NCT05374525)
- Testing
- APRETUDE, Cabotegravir OLI
- Where
- 17 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Seriously Ill Patients, Cancer
Goals of Care Conversations Study
The long term goal is to improve quality of care in Veterans with serious illnesses by aligning medical care with Veterans' goals and values.
- Conditions
- Seriously Ill Patients, Cancer, Heart Failure, Interstitial Lung Disease
- Trial name
- LSTDI (NCT05001009)
- Testing
- Clinician Implementation Strategy Stage 1: low intensity clinician training, Clinician Implementation Strategy Stage 2: high intensity clinician training, Low patient engagement
- Where
- 3 sites in United States
- Volunteers
- 2,859 people
- Sponsor
- VA Office of Research and Development
Anxiety, Depression
Sibling-Support for Adolescent Girls (SSAGE)
Forcibly displaced adolescents face increased risks for mental illness and distress, with adolescent girls disproportionately affected in part due to the heightened gender inequity that often accompanies forced displacement.
- Conditions
- Anxiety, Depression, Mental Illness
- Trial name
- NCT06078124
- Testing
- Sibling Support for Adolescent Girls in Emergencies
- Where
- Colombia
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Health Behavior
Training LHDs to Disseminate Evidence-Based Interventions to Small Worksites
The proposed project will advance implementation science by comparing the effectiveness of different levels of technical support in an important but understudied community-based setting: local health departments.
- Trial name
- NCT03930420
- Testing
- Connect to Wellness
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Washington
Diabetes
Using Practice Facilitation and Operationalizing Referral Information Technology to Increase DSMES Utilization
This is a pilot and feasibility study of a pragmatic cluster randomized trial that utilizes health information technology and practice facilitation to address referral barriers and increase clinician awareness and motivation to…
- Trial name
- NCT05472142
- Testing
- UP FOR IT - practice facilitation, UP FOR IT - health information technology
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Mary Lacy
Independent Living
Implementation of CAPABLE in the Michigan Medicaid Waiver
Main study: Nearly half of older adults report problems with function, which can lead to difficulty with activities of daily living and nursing home placement.
- Trial name
- NCT03634033
- Testing
- MiCAP with IF (Main Study), MiCAP with IF and EF (Main Study), MiCAP with IF and Caregiver Engagement (Administrative Supplement)
- Where
- 18 sites in United States
- Volunteers
- 7,777 people, healthy volunteers welcome
- Sponsor
- Grand Valley State University
Hepatitis C
eHealth Partnered Evaluation Initiative - Evaluation of the Initial Deployment of VA's Annie Texting System
Conduct a rigorous formative evaluation of the initial deployment of the Annie texting system across several pilot test sites and from these findings, develop and test an augmented implementation strategy to facilitate more rapid…
- Trial name
- AnnieEval (NCT03898349)
- Testing
- Annie text messaging system, Annie text messaging system with Usual implementation, Annie text messaging system with Augmented implementation
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- VA Office of Research and Development
Pulmonary Disease, Chronic Obstructive, Smoking
Electronic Proactive Outreach for Smokers With COPD
Chronic obstructive pulmonary disease (COPD) is one of the most common respiratory diseases, with 90% of cases directly attributable to smoking. Unfortunately, many patients continue to smoke and have an urgent need to quit.
- Trial name
- NCT04462289
- Testing
- Proactive Outreach
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- VA Office of Research and Development
Colorectal Cancer, Cancer
Effectiveness and Implementation of mPATH-CRC
Study Investigators are conducting this study to learn how to best implement a new iPad program in clinical practice.
- Conditions
- Colorectal Cancer, Cancer, Rectum Cancer, Colon Cancer
- Trial name
- NCT03843957
- Testing
- mPATH-CRC, mPATH-Checkin, "high touch" Implementation strategy
- Where
- United States
- Volunteers
- 77,145 people
- Sponsor
- Wake Forest University Health Sciences
Psychiatric Emergency
Telepsychiatry to Enable Expedited Disposition of Psychiatric Emergencies
The goal of this observational study is to examine the effect of using a video link for evaluation of patients in the psychiatric emergency room.
- Trial name
- NCT05771545
- Testing
- Telepsychiatry
- Where
- 8 sites in Israel
- Volunteers
- 959 people
- Sponsor
- Hebrew University of Jerusalem
Post-traumatic Stress Disorder
Increasing Engagement in Evidence-Based PTSD Therapy for Primary Care Veterans
The purpose of this study is to implement an evidence-based Referral Management System that will address patient and system-level barriers to the uptake of evidence-based psychotherapy for PTSD by Veterans Affairs primary care…
- Trial name
- NCT01984515
- Testing
- Referral Management System
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
HIV Infections
A Study Evaluating Implementation Strategies for the Delivery of APRETUDE for Black cis-and Transgender Women in United States EHE Territories
The purpose of the study is to evaluate the appropriateness, adoption, feasibility, fidelity, and acceptability of implementation strategies and Cabotegravir (CAB) pre-exposure prophylaxis (PrEP).
- Trial name
- EBONI (NCT05514509)
- Testing
- APRETUDE, Cabotegravir tablet
- Where
- 22 sites in United States
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Early Ambulation
Implementing a Hospital-Based Walking Program (STRIDE): Function QUERI 2.0
Implementing a Hospital-Based Walking Program (STRIDE): Function QUERI 2.0 aims to compare implementation strategies for large-scale spread of STRIDE, a supervised walking program for hospitalized older Veterans.
- Trial name
- STRIDE (NCT04868656)
- Testing
- Implementation Strategy: Foundational Support, Implementation Strategy: Enhanced Support
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- VA Office of Research and Development
HIV Infections
A New APPROACH to HIV Testing: Adaptation of POCT for Pharmacies to Reduce Risk and Optimize Access to Care in HIV
An estimated 21% of Canadians with HIV are unaware of their infection. There is a need to improve access to HIV testing to detect infections earlier so individuals can access care early and take steps to prevent transmission to…
- Trial name
- APPROACH (NCT03210701)
- Testing
- A HIV POCT program adapted for & provided by community pharmacists
- Where
- Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Knee Osteoarthritis
Implementing Group Physical Therapy (PT) for Veterans With Knee Osteoarthritis (Group PT): Function QUERI 2.0
Implementing Group Physical Therapy (PT) for Veterans with Knee Osteoarthritis (OA): Function QUERI 2.0 (Group PT) aims to implement, evaluate and sustain Group PT in 16 VA sites using a type III effectiveness-implementation…
- Trial name
- Group PT (NCT05282927)
- Testing
- Implementation Strategy: Foundational REP, Implementation Strategy: Enhanced REP (enREP)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Suicidal Self-directed Violence, Suicidal Preparatory Behavior
Maintaining Implementation Through Dynamic Adaptations (MIDAS) Suicide Prevention 2.0 Clinical Telehealth
Scientific advances are constantly leading to better treatments. However, it is quite challenging for healthcare systems, including VA, to ask very busy providers to change the way they practice.
- Trial name
- MIDAS SPCT (NCT06011759)
- Testing
- Academic Detailing (AD), LEAP
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- VA Office of Research and Development
Smoking, Tobacco, Mental Illness
Proactive Outreach for Smoking Treatment
Tobacco use disorder is a chronic disease. This is particularly true for people living with mental illness, who are more likely to smoke and make more unsuccessful quit attempts than those without.
- Trial name
- POST (NCT04988477)
- Testing
- Study 3: Chronic care management, Study 2: Pilot trial
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Sandra Japuntich
Alcohol Drinking
Implementing Mobile Technology for Unhealthy Alcohol Use
Scalable approaches are needed to support patients identified in the emergency department as unhealthy alcohol users and text messaging intervention approaches are a promising solution.
- Trial name
- NCT05350878
- Testing
- Implementation Intervention
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- UConn Health
Medication Therapy Management, Implementation Science
Senior PharmAssist: Co-Design and Evaluation of a Toolkit to Promote Scalable Implementation
This project aims to evaluate the scalability of an established, evidence-based, multi-component intervention, Senior PharmAssist^TM (SPA), designed to improve function and quality of life of older adults with limited incomes.
- Trial name
- NCT05278650
- Testing
- Senior PharmAssist^TM Program Implementation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University