Clinical trials: Implementation Strategies
Behavior Disorders
Remote Training in Rural Schools
Rural areas have fewer, and less well trained, health care providers than non-rural areas. Schools have become more involved in the delivery of mental health services and hold great potential for increasing access to children and…
- Trial name
- NCT05034198
- Testing
- Coping Power Program (CPP), Cognitive behavioral therapy (CBT) for Anxiety Treatment in Schools (CATS), Check-in/Check-out (CI/CO)
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Hypertension, Health Services Accessibility
A Combination Triple Pill Implementation Strategy for Blood Pressure cONtrol
This study includes a survey of primary healthcare facilities in Nigeria and Sri Lanka. It will aim to assess the availability and readiness of hypertension care in primary healthcare facilities, and feasibility to conduct a…
- Trial name
- ACTION (NCT07784647)
- Where
- 2 sites in Nigeria, Sri Lanka
- Volunteers
- 1,444 people, healthy volunteers welcome
- Sponsor
- Imperial College London
HIV Infections
A Study Evaluating Implementation Strategies for the Delivery of Cabotegravir in Low and High-Volume PrEP Site in the United States
This is a two-arm study evaluating the impact of two implementation strategy conditions, dynamic implementation and routine implementation on the feasibility of delivering of Cabotegravir PrEP in low and high-volume PrEP sites in…
- Trial name
- PILLAR (NCT05374525)
- Testing
- APRETUDE, Cabotegravir OLI
- Where
- 17 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Type Two Diabetes Mellitus
Scaling up the DSMES Learning Collaborative
A multicomponent implementation strategy bundle designed to improve Diabetes Self-Management Education and Support (DSMES) referral and utilization in rural primary care clinics.
- Trial name
- NCT07888179
- Testing
- Multicomponent Implementation Strategy (MCIS) Bundle, Standard of Care
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mary Lacy
Firearm Safety, Firearm Safety Storage
Firearm Secure Storage Device Distribution RCT
This study aims to learn how to best promote safe firearm storage in the community. Firearm injuries are a major public health concern, and securely storing firearms can help prevent accidental injuries, suicide, and unauthorized…
- Trial name
- NCT07886983
- Testing
- Cable locks, Lock box, Lock box and cable locks
- Where
- United States
- Volunteers
- 1,858 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Mild Cognitive Impairment, Mild Cognitive Impairment (MCI)
Community-based Multi-domain Intervention to Detect and Delay Cognitive Decline in Community-dwelling Older Adults: A Pilot Study
The incidence of cognitive impairment and its burden are increasing with a rapidly ageing population. In Singapore, the prevalence of dementia among older adults aged 60 and above is approximately 10%, which will translate to…
- Trial name
- NCT07099040
- Testing
- Social support, Health coaching, Physical Activity
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Obesity
Developing and Testing Implementation Strategies for Evidence-Based Obesity Prevention in Childcare
Investigators will pilot test the impact of an enhanced implementation strategy on implementation and child health outcomes using continuous formative evaluation.
- Trial name
- NCT03075085
- Testing
- WISE (We Inspire Smart Eating)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Back Pain
Self-management of Low Back Pain in Horticulture Workers
The primary purpose of this hybrid Type II comparative effectiveness and implementation study is to compare two self-management strategies in nursery and landscape workers.
- Trial name
- NCT06153199
- Testing
- Self-management videos, Check lists for ergonomic options, Text reminders
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University of Florida
HIV Infections
The Test-to-PrEP Study
To compare the effectiveness of two social network strategies (direct distribution and referral-based distribution) in increasing HIV self-testing (HIVST) completion rates among social network contacts of current Pre-Exposure…
- Trial name
- NCT06927856
- Testing
- Test-to-PrEP, Access by Referral
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Miami
Acceptability, Feasibility Studies
Digital Support Strategies for Caregiver Home Practice
This project is a pilot trial of the Engaging Families home practice smartphone application (or "app") as an add on to a family-based prevention program.
- Trial name
- NCT06907966
- Testing
- Engaging Families home practice app, Scheduling app
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Smoking Cessation
Designing an Implementation Strategy for Lung Screening and Smoking Cessation Treatment in Community Health Centers
Tobacco use is the leading preventable cause of death in the US and a major driver of health disparities. Among our tools for reducing the harms of tobacco is lung cancer screening (LCS).
- Trial name
- SAILS-FQHC (NCT05447897)
- Testing
- Qualitative Group Interviews, Stakeholder advisory group
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Mental Health Disorder
Dissemination Strategies and Implementation Outcomes of Adolescent Character Strength Interventions.
The present research study will involve investigating the efficacy of large-scale dissemination models of evidence-based character strength interventions in secondary schools in Kenya.
- Trial name
- NCT05365503
- Where
- 3 sites in Kenya
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Shamiri Institute
Autism Spectrum Disorder
Translating Evidence-based Interventions for ASD: Multi-Level Implementation Strategy
The purpose of this study is to test the effectiveness of the "Translating Evidence-based Interventions (EBI) for ASD: Multi-Level Implementation Strategy" (TEAMS) model on provider-level implementation outcomes when used to…
- Trial name
- TEAMS (NCT03380078)
- Testing
- Teams Leadership Institute (TLI), Motivational Enhancement (TIPS for Training), Classroom Pivotal Response Teaching (CPRT)
- Where
- 3 sites in United States
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Suicide
Implementing Evidence Informed Practices in Schools to Address LGBTQ Adolescent Suicide
Reducing youth suicide in the U.S. is a national public health priority. Sexual and gender minority adolescents are at elevated risk for suicide. Safer school environments, however, can decrease this risk.
- Trial name
- RLAS (NCT02875535)
- Testing
- RLAS
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Parenting Intervention, Maltreatment
Early Test of an Innovative Child Maltreatment (CM) Prevention Strategy
Millions of children are victims of maltreatment each year in the United States. Research on home visiting programs show that child maltreatment can be prevented; however, these programs struggle to reach families in need and…
- Conditions
- Parenting Intervention, Maltreatment, Prevention
- Trial name
- (CM) (NCT06912685)
- Testing
- Technology Enhanced Implementation Package, SafeCare
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
HIV Prevention
Pre-exposure Prophylaxis (PrEP) Adherence for Black MSM
The goal of this clinical trial is to learn if two interventions-C4 and C4+3MV-can improve PrEP adherence (taking medication to prevent HIV) among Black men who have sex with men (MSM).
- Trial name
- C4+3MV (NCT06661343)
- Testing
- C4 Program, C4 + 3MV Program
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yale University
Post-traumatic Stress Disorder, Leadership
Testing the LOCI Intervention
The project will develop knowledge on how managers can lead the implementation of practices that have proven to be effective for post-traumatic stress disorders (PTSD) in child and adult specialized mental health services.
- Trial name
- NCT03719651
- Testing
- LOCI, EMDR, CT-PTSD
- Where
- Norway
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Human Papillomavirus Vaccines
Increasing Optimal Use of HPV Vaccination in Primary Care
Washington University will evaluate the effectiveness of a multi-component implementation strategy to increase use of HPV vaccine in primary care practices.
- Trial name
- NCT04180462
- Testing
- Practice Facilitation, Education, Audit and Feedback
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Malaria Infection, Malaria Vaccines
Comparison of Two Strategies for Administering the R21-Matrix M Vaccine in a Context of Seasonal Malaria Transmission in Chad
This is a two-arm, cluster-randomised, phase IV trial conducted in Chad to assess the protective efficacy and impact in real-life conditions of a new strategy for administering the R21/MM malaria vaccine, synchronized within a…
- Trial name
- COSAV-R21 (NCT07038837)
- Testing
- "Synchronised" arm (intervention)
- Where
- Chad
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Epicentre
Attention Deficit Hyperactivity Disorder Symptoms
Implementation Strategy Resource Package for Behavioral Classroom Interventions: Pilot Test
The purpose of this study is to pilot test for feasibility and initial promise an implementation strategy resource package that aims to support teachers in using behavioral classroom management interventions for children with…
- Trial name
- NCT05489081
- Testing
- Positive Behavior Management Toolkit
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia