Clinical trials: Impulse Control Disorders
Pathological Gambling
An Open-Label Study of N-Acetyl Cysteine in Pathological Gambling
After completing all screening evaluations, subjects will receive unblinded N-Acetyl Cysteine 600 mg/day for 2 weeks. The dose will be raised to 1200 mg/day at visit 4 and to 1800 mg/day at visit 6 unless clinical improvement has…
- Trial name
- NCT00273702
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pathological Gambling
Dopamine Responsivity in Gamblers
This study deals with how people decide between rewards of different value. The investigators want to understand how the brain's dopamine system impacts this kind of decision making.
- Trial name
- NCT02772978
- Testing
- Tolcapone
- Volunteers
- 19 people
- Sponsor
- University of California, San Francisco
Trichotillomania, Obsessive Compulsive Disorder
Marinol in Trichotillomania or Obsessive Compulsive Disorder
The goal of the proposed study is to evaluate the efficacy and safety of dronabinol in individuals with obsessive-compulsive disorder (OCD) or the obsessive-compulsive spectrum disorders, trichotillomania (TTM) or pathological…
- Trial name
- NCT01093976
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Chicago
Trichotillomania, Hair Pulling Disorder
Milk Thistle in Trichotillomania in Children and Adults
The goal of the proposed study is to evaluate the efficacy and safety of silymarin (milk thistle) in children and adults with trichotillomania.
- Trial name
- NCT02473913
- Testing
- Milk Thistle
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Chicago
Child, Only, Chronic Renal Failure in Children
The Effect of a Mobile Game Application on Children With CRF
The aim of this study was to investigate the effect of a mobile game application developed for children with Chronic Renal Failure (CRF) on disease management. The study was a randomized controlled trial.
- Conditions
- Child, Only, Chronic Renal Failure in Children, Gambling, Disease
- Trial name
- NCT07162220
- Testing
- The clinic's routine education program, Mobile game app
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Akdeniz University
Trichotillomania
A Study in Patients With Trichotillomania
The purpose of this study is to explore the safety, tolerability and activity of SXC-2023 when dosed for 6 weeks versus placebo in adult patients with moderate to severe Trichotillomania.
- Trial name
- TTM (NCT03797521)
- Testing
- SXC-2023
- Where
- 13 sites in United States
- Volunteers
- 128 people
- Sponsor
- Promentis Pharmaceuticals, Inc.
Migraine Disorders, Brain, Healthy Adult Participants
Effect of Atogepant on the Vestibulo-Ocular Reflex in Healthy Adults and Adults With Migraine
Researchers want to find out how a substance in the body called CGRP affects balance. CGRP (calcitonin gene-related peptide) is a small protein involved in migraine. Several approved migraine medicines work by blocking it.
- Conditions
- Migraine Disorders, Brain, Healthy Adult Participants, Vestibulo-Ocular Reflex
- Trial name
- VOR-GRIP (NCT07826910)
- Testing
- Atogepant 60 mg
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Konrad Peter Weber
Gambling, Pathological
Adding Contingency Management to Treatment as Usual for Disordered Gambling.
The aim of this study is to conduct a trial to investigate the efficacy of adding Contingency Management (CM) to Treatment as Usual (TAU) for the treatment of Disordered Gambling.
- Trial name
- NCT02613754
- Testing
- Contingency Management, Treatment as Usual
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Lethbridge
Parkinson's Disease, Non-motor Symptoms
Objective Assessment of Behavioural Disorders in PD
The aim of this project is to measure behavioural disorders in Parkinson's disease (PD) patients in a more objective way, in order to facilitate the detection of those symptoms and improve the treatment of non-motor symptoms in…
- Trial name
- TECHNO-PARK (NCT04611581)
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Intermittent Explosive Disorder
A Comparison of Fluoxetine and Divalproex for the Treatment of Intermittent Explosive Disorder
This study will compare the medications fluoxetine (Prozac®) and divalproex (Depakote®) for the treatment of aggressive behavior in individuals with Intermittent Explosive Disorder (IED).
- Trial name
- NCT00078754
- Testing
- Fluoxetine, Divalproex
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Chicago
Gambling, Pathological Gambling
Indicated Prevention With At-Risk Gamblers
The overall purpose of this study is to reduce the prevalence of gambling risk in college students by evaluating the effectiveness of different treatments in reducing gambling behavior and related negative consequences.
- Conditions
- Gambling, Pathological Gambling, Problem Gambling
- Trial name
- NCT00078273
- Testing
- Personalized Feedback Intervention, Cognitive Behavioral Intervention
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- University of Washington
Gambling Disorder
Effect of High-Intensity Transcranial Alternating Current Stimulation on Gambling Disorder: A Randomized Controlled Trial
The investigators assume that High-intensity transcranial Alternating Current Stimulation (HI-tACS) could improve gambling disorder patients' executive-control function by modulating abnormal neural activity, particularly…
- Trial name
- HITACSRCT-GD (NCT07228182)
- Testing
- HI-tACS
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Substance Use Disorder
OPAL: "Opiates and PhArmacoLogy"
The aim of this study is to determine the current prevalence of co-addictions, including problem/pathological gambling, in patients receiving Opiate Substitution Treatment (OST), and to then compare patients receiving OST with or…
- Trial name
- OPAL (NCT01847729)
- Where
- 7 sites in France
- Volunteers
- 263 people
- Sponsor
- Nantes University Hospital
Addictive Behaviors, Internet Addiction Disorder
Is Craving a Central Criterion for Diagnosing a Behavioral Addiction?
This study is a cross-sectional observational study designed to evaluate the diagnostic criteria for behavioral addictions (gambling, online video game disorder, screen addiction, food addiction, and pathological use of sex…
- Conditions
- Addictive Behaviors, Internet Addiction Disorder, Gambling, Technology Addiction
- Trial name
- CRIBA (NCT07854912)
- Testing
- Questionnaires, Telephone interview
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Gambling
Drug Treatment for Pathologic Gambling Disorder
This study will establish the best dose of the drug naltrexone to treat patients with Pathological Gambling Disorder (PGD) and severe urge symptoms.
- Trial name
- NCT00053677
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Compulsive Buying
Memantine Treatment of Compulsive Buying
This is an 8-week, open-labe study of memantine in the treatment of compulsive buying.
- Trial name
- NCT00830375
- Testing
- Memantine
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Minnesota
Transcutaneous Electric Nerve Stimulation, Gambling
Brain Mechanism and Intervention of Executive-control Dysfunction Among Gambling Disorder
The investigators assume that transcranial Alternating Current Stimulation (tACS) could improve gambling disorder patients' executive-control function by adjusting the synchronization patterns and enhancing the functional…
- Trial name
- NCT06195995
- Testing
- Transcranial alternating current stimulation-true stimulus
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Mental Health Center
Gambling Disorder
Don't Go There: A Geospatial mHealth App for Gambling Disorder
The goal of this project is to develop and to test the efficacy of a novel mHealth app for gambling disorder. The app capitalizes on smartphones' global positioning software (GPS) that recognizes a user's location to within 15…
- Trial name
- NCT04158037
- Testing
- mHealth App
- Where
- United States
- Sponsor
- St. Louis University
Obsessive Compulsive Disorder, Body Dysmorphic Disorder
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
To examine the effectiveness and clinical care outcomes of cognitive-behavioral therapy interventions at Massachusetts General Hospital (MGH).
- Conditions
- Obsessive Compulsive Disorder, Body Dysmorphic Disorder, Tourette Syndrome, Trichotillomania
- Trial name
- NCT01075672
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Massachusetts General Hospital
Pathological Gambling
Repeated Low-frequency Transcranial Magnetic Stimulation Reduces Cue-induced Craving: a Randomized, Prospective, Double-blind, Sham-controlled, Cross-over Study
The aim of this study is to evaluate the effect of repeated low-frequency Transcranial Magnetic Stimulation (rTMS) of the right dorsolateral prefrontal cortex, combined with gambling cues, on gambling craving.
- Trial name
- STIMJEU (NCT01560351)
- Testing
- rTMS
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Nantes University Hospital