Clinical trials: Impulse-Control Disorders
Delayed Sleep Phase
Delayed Sleep Timing in Teens Study
This study will (1) comprehensively characterize the substance use disorder (SUD) risk profile associated with adolescent Delayed Sleep Phase (DSP), and (2) probe whether SUD risk is diminished by altering sleep/circadian timing.
- Trial name
- NCT03806296
- Testing
- Increase morning bright light, Decrease evening blue light, Sleep scheduling
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy
Detecting a Reward Signal in the Motor Cortex
This study will use transcranial magnetic stimulation (TMS) to determine whether the activity in the brain when someone wins something affects the part of the brain that controls movement.
- Trial name
- NCT00422071
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alcohol Use Disorder, Intermittent Explosive Disorder
Neural Correlates During Alcohol Intoxication
Alcohol intoxication is responsible for a large proportion of violent crime/assault and personal injury in our society. While a number of variables have been associated with alcohol-related aggression, high trait aggression and…
- Trial name
- NCT06118580
- Testing
- Alcohol (Ethanol)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Parkinson's Disease
Acamprosate for Treatment of Compulsive Behaviors and Craving in Parkinson's Disease
The purpose of this study is to determine how many patients with Parkinson's disease have compulsive behaviors, and what types of behaviors they have.
- Trial name
- NCT00640952
- Testing
- acamprosate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Drug Addiction, Vulnerability to Substance Addiction
Individual Differences in Reward and Impulse Control
Background: The risk for becoming addicted to drugs varies among individual, even those using similar drugs in a similar way. It is not known why some people become addicted and others do not.
- Trial name
- NCT01621607
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tourette Syndrome
Impulse Control in Gilles de la Tourette Syndrome
The study intends to evaluate the role of Mirror Neurons in the determination of gestures, words, and repetitive vocalizations in subjects affected by Tourette's syndrome and to verify if these subjects are faster to assemble…
- Trial name
- NCT04197804
- Testing
- Routine tests perform
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Migraine Disorders, Brain, Healthy Adult Participants
Effect of Atogepant on the Vestibulo-Ocular Reflex in Healthy Adults and Adults With Migraine
Researchers want to find out how a substance in the body called CGRP affects balance. CGRP (calcitonin gene-related peptide) is a small protein involved in migraine. Several approved migraine medicines work by blocking it.
- Conditions
- Migraine Disorders, Brain, Healthy Adult Participants, Vestibulo-Ocular Reflex
- Trial name
- VOR-GRIP (NCT07826910)
- Testing
- Atogepant 60 mg
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Konrad Peter Weber
Pathological Gambling
Community Reinforcement Approach and Family Training (CRAFT) for Problem Gambling
Nova Scotia is experiencing a proliferation of gambling opportunities and their related gambling problems. The 2003 Nova Scotia Prevalence Study (2004) found that approximately 50,000 adult Nova Scotians are at some risk for…
- Trial name
- NCT01340274
- Testing
- CRAFT treatment, Treatment as Usual
- Where
- 3 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Colchester East Hants Health Authority
Gambling, Opioid
Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray
Non-controlled pilot study. Two groups: Group A: naloxone nasal spray max 8 mg/per day; Group B: naloxone max 16 mg/per day. Study duration 8 weeks. Brief intervention.
- Conditions
- Gambling, Opioid, Naloxone, Spray
- Trial name
- NALPILO (NCT03223896)
- Testing
- Naloxone hydrochloride 20mg/ml
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Gambling
Effects of Positive Psychological Group Psychotherapy and Auricular Acupressure on Withdrawal Symptoms
Objective The purpose of this study is to examine the effects of auricular acupressure and group counseling with positive psychology on gambling severity, withdrawal symptoms, and dopamine.
- Trial name
- NCT05241041
- Testing
- group counseling, auricular acupressure
- Where
- South Korea
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Inha University Hospital
Gambling Disorder
Online Intervention to Promote Change and Help-Seeking in Young Adults With Gambling and Trading Problems
The goal of this study is to investigate if personalized online normative feedback (PONF) can increase intention to change and help-seeking behaviors in young adults with gambling or trading problems in Spain.
- Trial name
- NCT06681103
- Testing
- Personalized Normative Feedback
- Where
- Spain
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Gambling Disorder
BANCO Study: Behavioral Addictions and Related NeuroCOgnitive Aspects: A Monocentric, Prospective, Controlled, Open-label Study of a Sample of Patients With Gambling Disorder
The prevalence of people suffering from gambling disorder is relatively high, and the impact on this disorder the individual and those around him is considerable.
- Trial name
- BANCO (NCT03202290)
- Testing
- Cognitive and clinical assessment
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Gambling
Biomarkers of Online Gambling Addiction
The purpose of this study is to identify alterations of motivational processes related to decision making in uncertainty condition associated with gambling addiction: by studying the dynamics between brain systems involved in…
- Trial name
- BLUNDER (NCT02862821)
- Testing
- HR-EEG
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Impulse Control Disorders
Fingerprinting of Impulsivity
The study aims to examine a battery of behavioral and questionnaire measures in 4 disorders clinically associated with impulsivity and in health controls, to: 1) investigate if the different populations have a distinct behavioral…
- Trial name
- NCT02722174
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Intermittent Explosive Disorder
Inflammatory Challenge in Human Aggression.
The goal of this clinical trial is to explore the differences in behavioral and cytokine response to a low dose infusion of endotoxin (vs.
- Trial name
- LPSS (NCT06665074)
- Testing
- Endotoxin (E. coli O:113, Reference Endotoxin)
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Asthma, Small Airway Disease
The Prevalence Of Small Airways Dysfunction In Asthma Patients And The Impact On The Asthma Control
Asthma, which are one of the most important causes of morbidity and mortality both in the world and in our country, constitute a very serious social and economic burden.
- Trial name
- NCT04375995
- Testing
- Impulse oscillometry, Spirometric pulmonary function test, Fractional exhaled nitric oxide (FENO) test
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Sibel Naycı
Anger, Intermittent Explosive Disorder
Maladaptive Anger Treatment
From a psychoevolutionary perspective, anger is a universal emotion that can serve the function of making us aware of wrongdoing and motivating us to undo/correct the wrongdoing.
- Conditions
- Anger, Intermittent Explosive Disorder, Emotional Distress, Aggression
- Trial name
- NCT06275607
- Testing
- Cognitive Behavioral Affective Therapy, Emotional Discussion
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas at San Antonio
Intermittent Explosive Disorder
Pimavanserin and Aggression and Social Cognition.
The investigators are studying how certain drugs can reduce anger outbursts in people with anger problems. In this study the investigators seek to determine if a single 34 mg (two 17 mg tablets) oral dose of the 5-HT2a receptor…
- Trial name
- NCT05895513
- Testing
- Pimavanserin 34 mg
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Impulse Control Disorders, Borderline Personality Disorder
fMRI in Impulsivity
This study aims to use resting-state and task based functional Magnetic Resonance Imaging (fMRI) as a tool to evaluate trait characteristics of impulsivity in subjects with borderline personality disorder.
- Trial name
- NCT02755181
- Testing
- Experimental
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Overweight and Obesity
Effect of Transcranial Direct Current Stimulation (tDCS) and Probiotic Supplementation in Overweight Adults
The aim of the current study is to investigate and compare the effectiveness of probiotic supplementation and tDCS stimulation on risky decision-making related to food choices in overweight people.
- Trial name
- NCT06035718
- Testing
- Probiotic Blend Capsule, tDCS
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Tehran