Clinical trials: In Vitro Fertilization (IVF)
Infertility
Swanson-Based Supportive Care for Infertility Stress and Coping in Couples Undergoing ART
The goal of this clinical trial is to learn if supportive care based on Swanson's Caring Theory can reduce stress and improve coping in couples undergoing infertility treatment with assisted reproductive treatment (ART)…
- Trial name
- NCT07557069
- Testing
- Swanson Caring Theory-based supportive care
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ondokuz Mayıs University
Conventional IVF, ICSI
Child Follow-up in Women Treated With Conventional IVF or ICSI
To compare the physical, mental and motor development of babies born from pregnancy using ICSI technique and and conventional IVF in non-male factor infertile couples.
- Trial name
- NCT04866524
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 322 people
- Sponsor
- Mỹ Đức Hospital
Infertility, Female, IVF
Fertility Supportive Behavior Education Based On Watson's Theory Of Human Care
Infertile individuals frequently attempt behavioral changes to enhance the effectiveness of their treatment and improve fertility outcomes.
- Trial name
- NCT06591637
- Testing
- Fertility supportive behavior education based on Watson's Theory of Human Care, Routine nursing care, The booklet "Fertility-Supporting Health Training
- Where
- Palestinian Territories
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
in Vitro Fertilization
AOA Versus Non-AOA in Low Prognosis Patients by the POSEIDON Criteria
Poor ovarian response (POR) remains one of the significant challenges of Assisted Reproductive Technology (ART). Facing difficulties related to clinical practice, optimizing the embryo culture process is necessary to improve the…
- Trial name
- NCT05402605
- Testing
- ICSI with AOA, ICSI without AOA
- Where
- Vietnam
- Volunteers
- 528 people
- Sponsor
- Mỹ Đức Hospital
Repeated IVF Failure, Microbiota
The Role of the Physiological Endometrial Microbiota in Assisted Reproduction Outcomes
The goal of this observational study is to investigate the influence and contribution of the normal composition and balance of the endometrial microbiota on the achievement of embryo implantation and the maintenance of pregnancy…
- Trial name
- no exist (NCT07606053)
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Assisting Nature
Female Infertility
Impact of Clomiphene Citrate Administration During the Early Luteal Phase on Endocrine Profile in IVF Cycles
The purpose of this study is to evaluate the effect on LH levels of the 5-day CC administration during luteal phase in oocyte donors, to investigate whether the CC corrects the suppressed LH levels in the luteal phase and whether…
- Trial name
- CLOFA (NCT01791751)
- Testing
- Clomifene Citrate
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fundació Privada Eugin
Infertility
Atrificial Shrinkage of Blastocyst Before In Vitro Fertilization
Vitrification is a modern cryopreservation technique based on sudden cooling of reproductive cells to a temperature of -196 ° C in seconds that produces glass-like solidification of a solution without crystallization, but by…
- Trial name
- NCT04125017
- Testing
- ICSI with laser pulse, ICSI with micro needle technique
- Where
- Egypt
- Volunteers
- 409 people
- Sponsor
- Aljazeera Hospital
Anxiety, Infertility, Female
Stress and Fertility: How to Lower Stress When Trying to Conceive
Psychological stress and its sources differ among the population and can be reduced in various ways. The practice of yoga has been shown to be an effective stress reducing agent.
- Trial name
- NCT03031990
- Testing
- In-person yoga for fertility group, Online yoga for fertility group, In person discussion only group
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Fertility Centers of Illinois
IVF
Luteal Phase Estradiol Support for In Vitro Fertilization/Intracytoplasmic Sperm Injection Cycles
Optimizing in vitro fertilization (IVF) success is more important than ever, in light of new public funding of IVF in Ontario, Canada.
- Trial name
- NCT02677259
- Testing
- 17-beta estradiol, Micronized progesterone
- Volunteers
- 506 people, healthy volunteers welcome
- Sponsor
- One Fertility
DNA Damage, Other Complications Associated With Artificial Fertilization
Polscope Sperm: A Non-invasive Method to Assess DNA Damage in Individual Sperm
The purpose of this study is to find a non-invasive way to discover DNA (deoxyribonucleic acid, which is the genetic material inside your cells) alterations in the sperm's head, in the near future leading us to choose the "good…
- Trial name
- NCT01461395
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Pregnancy, Immune Tolerance
Mechanisms of Maternal Immune Tolerance in Early Pregnancy
This study explores the mechanisms of maternal immune tolerance in early pregnancy by characterizing immune cell profiles and functional pathways during the first trimester.
- Conditions
- Pregnancy, Immune Tolerance, In Vitro Fertilization
- Trial name
- NCT07297394
- Testing
- Blood sampling
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Basel, Switzerland
Covid-19 Vaccination
The Effect of Covid-19 Vaccination in Patients Undergoing IVF
Since emerging in the last months of 2019, over 127 000 000 individuals have suffered severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, and the documented death toll from coronavirus disease 2019 (COVID-19)…
- Trial name
- Covid-19 (NCT05063942)
- Volunteers
- 712 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
In Vitro Fertilization, Infertility
Sibling Oocyte Study of Medium for In Vitro Fertilization/Intracytoplasmic Sperm Injection (IVF/ICSI) With no Human Serum Albumine
The purpose of this study is to determine if a new medium with no human serum albumine added is as good as the media conventionally used for IVF/ICSI.
- Trial name
- NCT00541892
- Testing
- Medium with no human serum albumine added, Conventional medium
- Where
- Norway
- Sponsor
- Sykehuset Telemark
In Vitro Fertilization, Stress
What Amount of Stress is Enough for a Successful Conception?
The aim of the study is to determine whether premedication with midazolam before oocyte aspiration in IVF procedures affects the amount of (oxidative) stress in women undergoing IVF and whether stress is also transmitted to the…
- Conditions
- In Vitro Fertilization, Stress, Midazolam Adverse Reaction, Stress, Emotional
- Trial name
- NCT04160611
- Testing
- Midazolam 7.5mg
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- University Hospital Sestre Milosrdnice
Male Infertility
Impact of Folates in the Care of the Male Infertility
Unexplained male infertility is increasing, and, nowadays, the investigators only can propose palliative treatment, as In VITRO Fertilization (IVF). The folate metabolism is a key for the maintenance of genome integrity.
- Trial name
- FOLFIV (NCT01407432)
- Testing
- Folic acid
- Where
- France
- Volunteers
- 162 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fertility Disorders
Evaluating the Usability of the Product Kinder System Trial, Home Based Hormone for In-Vitro Fertilization (IVF) Monitoring System.
In-vitro fertilisation (IVF) treatment involves women undergoing hormone stimulation (drug dosing) to produce more oocytes (eggs) to increase their chances of fertilisation.
- Trial name
- NCT05634850
- Testing
- Kinder
- Where
- Singapore
- Volunteers
- 25 people
- Sponsor
- Planet Innovation
Infertility, PCOS
Metformin in Patients With PCOS and Predictors of Poor Ovarian Response Ongoing In-vitro Fertilization
Metformin should be administered with caution and could be potentially dangerous in infertile patients with PCOS who show a poor ovarian response and are undergoing gonadotropin-based ovarian stimulation.
- Conditions
- Infertility, PCOS, Prognosis for Poor Response
- Trial name
- NCT01208740
- Testing
- Metformin
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- University Magna Graecia
Infertility
Comparison of Vaginal and Intramuscular Progesterone in Vitrified-warmed Blastocyst Transfer Cycles
The aim of this study is to test the hypothesis that the pregnancy rates of women (ages 18-50 years) undergoing transfer of vitrified-warmed blastocysts (frozen at less than 41 years of age) as part of their IVF treatment are not…
- Trial name
- NCT02772120
- Testing
- Vaginal progesterone gel (Crinone® 8%), Intramuscular Progesterone
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Subfertility
RCT on the Effect of Endometrial Injury on Ongoing Pregnancy Rate in Subfertile Women Undergoing IVF
Implantation failure remains one of the major factors limiting success in IVF treatment. It was postulated that the local injury to endometrium induces secretions of cytokines and growth factors such as leukemia inhibitory…
- Trial name
- NCT01977976
- Testing
- Endometrial aspiration by pipelle
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Infertility
Effect of Recombinant Follicular Stimulating Hormone (FSH) Dosing Following Cori-follitropin Alfa
In the trial, women planned to be treated with 150μg corifollitropin alfa followed by rFSH in a fixed GnRH antagonist protocol will be asked to participate and sign the ICF.
- Trial name
- TBC (NCT03686852)
- Testing
- same medications but different dosages
- Where
- Belgium
- Volunteers
- 167 people
- Sponsor
- Universitair Ziekenhuis Brussel