Clinical trials: In-Hospital Cardiac Arrest
Out-of-hospital Cardiac Arrest
Tracheal Intubation vs. Bag-valve-mask Ventilation in Patients With Out-of-Hospital Cardiac Arrest _ CAAM STUDY
The aim of this study is to improve the management of patients in cardiac arrest, and this by comparing two initial airway management methods: Tracheal intubation and bag-valve-mask ventilation.
- Trial name
- CAAM (NCT02327026)
- Testing
- bag-valve-mask ventilation, tracheal intubation
- Where
- France
- Volunteers
- 2,043 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Patient Transfer to Intensive Care Unit (Procedure), Respiratory Arrest (Disorder)
Evaluation of the Patient Deterioration Warning System
The overall goal of the project is to reduce the number of unexpected patient deteriorations by 50% at Emergency Departments (ED) by investigating if the novel Patient Deterioration Warning Systems (PDWS), can improve clinicians'…
- Conditions
- Patient Transfer to Intensive Care Unit (Procedure), Respiratory Arrest (Disorder), Cardiac Arrest (Disorder), Patient Died in Hospital (Finding)
- Trial name
- PDWS (NCT03375658)
- Testing
- PDWS Intervension
- Where
- 2 sites in Denmark
- Volunteers
- 6,500 people
- Sponsor
- University of Southern Denmark
Arrest Cardio Respiratory
Free Iron and Out of Hospital Cardiac Arrest
Out of hospital cardiac arrest is associated with a poor prognosis. The aim of this study is to provide a better understanding of perturbations of iron metabolism after cardiac arrest and to analyze the impact on clinical…
- Trial name
- DESFER (NCT03491670)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Brest
Out-Of-Hospital Cardiac Arrest, Ventricular Fibrillation Sustained
Percutaneous Left Stellate Ganglion Block In Out-of-hospital Cardiac Arrest Due to Refractory VEntricular Arrhythmias (LIVE Study)
This is an observational, prospective study to verify the feasibility and practicability of percutaneous stellate ganglion block (PSGB) in patient suffering from a refractory out-of-hospital cardiac arrest (OHCA) due to a…
- Conditions
- Out-Of-Hospital Cardiac Arrest, Ventricular Fibrillation Sustained, Shockable Rhythm, Medical Etiology
- Trial name
- LIVE (NCT04168970)
- Testing
- PSGB
- Where
- 2 sites in Italy
- Volunteers
- 62 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Out-of-hospital Cardiac Arrest (OHCA)
Ventilation Performance and Feedback Simulation Trial
The study "Understanding the Effect of Feedback on Ventilation Performance of Rescuers in a Simulation Trial" will address treatments administered by Emergency Medical Services (EMS) during cardiopulmonary resuscitation (CPR) in…
- Trial name
- VENT-SIM (NCT07352709)
- Testing
- Real-time feedback
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas Southwestern Medical Center
in Hospital Cardiac Arrest, in Situ Simulation
Clinical Audit of Cardio Pulmonary Resuscitation Management in Adults Patient Units of Care by in Situ Simulation
Clinical audit of in-hospital cardiac arrest management by in situ simulation Objectives: correct latent safety threats, knowledge gap, and crisis resource management (CRM) Design: clinical audit, observational sudy.
- Conditions
- in Hospital Cardiac Arrest, in Situ Simulation, Clinical Audit, Education
- Trial name
- SIMACRIS (NCT02065934)
- Testing
- cardio-pulmonary resuscitation
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Out-Of-Hospital Cardiac Arrest, Heart Arrest
The PulsePoint Study
This randomized controlled trial will evaluate whether use of the PulsePoint system increases bystander CPR or defibrillator use compared to standard dispatch procedures in patients who suffer non-traumatic, out-of-hospital…
- Conditions
- Out-Of-Hospital Cardiac Arrest, Heart Arrest, Heart Diseases, Cardiovascular Diseases
- Trial name
- NCT04806958
- Testing
- PulsePoint notification
- Where
- 2 sites in United States, Canada
- Volunteers
- 340 people
- Sponsor
- Dr. Steven Brooks
Heart Arrest, Out-Of-Hospital
Calcium for Out-of-Hospital Cardiac Arrest
This is an investigator-initiated, multicenter, randomized, placebo-controlled, parallel group, double-blind, superiority trial of calcium during adult out-of-hospital cardiac arrest.
- Trial name
- COCA (NCT04153435)
- Testing
- Calcium Chloride, Sodium chloride 0.9%
- Where
- Denmark
- Volunteers
- 397 people
- Sponsor
- Lars Wiuff Andersen
Out-Of-Hospital Cardiac Arrest, Oxygen Toxicity
ORI to Reduce Hyperoxia After Out Hospital Cardiac Arrest
The investigator's research proposal is a randomized controlled study evaluating two different monitoring strategies to titrate FiO2 in order to rapidly and safely achieve optimal SatO2 targets during early ROSC of non-traumatic…
- Trial name
- ORI-ONE (NCT03653325)
- Testing
- ORI measurement, oxygen saturation measurement
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Out-of-hospital Cardiac Arrest
The PulsePoint Randomized Controlled Trial
"Sudden cardiac arrest" occurs when someone's heart stops beating unexpectedly. Each year, more than 45,000 Canadians have a cardiac arrest.
- Trial name
- NCT01746290
- Testing
- PulsePoint notification
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Cardiac Arrest, Out of Hospital Cardiac Arrest
Compression Only-CPR Versus Standard-CPR
Out-of-hospital cardiac arrest (OHCA) is one of the leading causes of mortality in the industrialized world. Bystander CPR before arrival of the Emergency Medical Service (EMS) is a positive predictor of survival.
- Trial name
- TANGO2 (NCT02401633)
- Testing
- CO-CPR, S-CPR
- Where
- Sweden
- Volunteers
- 1,250 people
- Sponsor
- Karolinska Institutet
Hypoxic Ischemic Encephalopathy
Targeted Temperature Management After In-Hospital Cardiac Arrest
The purpose of this study is to determine whether targeted temperature management at 36.0˚C(TTM-36) in patients who remain unconscious after resuscitation from in-hospital cardiac arrest(IHCA) will reduce death and disability…
- Trial name
- TTM36-IHCA (NCT02578823)
- Testing
- Arctic Sun®, Arcticgel™, Conventional antipyretic treatment
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Out-of-hospital Cardiac Arrest
Prehospital Resuscitation Intra Nasal Cooling Effectiveness Survival Study
Promising result of intra-arrest cooling on neurological intact survival in cardiac arrest patients has recently been published in the PRINCE-study in Circulation 2010.
- Trial name
- PRINCESS (NCT01400373)
- Testing
- Prehospital intra-nasal cooling with RhinoChill
- Where
- 2 sites in Belgium, Sweden
- Volunteers
- 700 people
- Sponsor
- Karolinska Institutet
Infections, Cardiac Arrest
Steroids and Post-resuscitation Infectious (Septic) Complications
Postresuscitation disease is characterized by post-insult systemic inflammation, adrenal insufficiency, and circulatory failure.
- Trial name
- NCT02408939
- Testing
- Stress-dose hydrocortisone
- Where
- 5 sites in France, Greece
- Volunteers
- 191 people
- Sponsor
- University of Athens
Hospital Rapid Response Team, Hospital Medical Emergency Team
Deep Learning Based Early Warning Score in Rapid Response Team Activation
The objective of this study is to evaluate the safety and clinical usefulness of the Deep learning based Early Warning Score (DEWS).
- Trial name
- NCT04951973
- Testing
- Deep Learning Based Early Warning Score (DEWS)
- Volunteers
- 50,000 people
- Sponsor
- Seoul National University Hospital
Wounds and Injuries, Out-of-Hospital Cardiac Arrest
Psychoactive Drug Use and Acute Care Use After Trauma and Out-of-Hospital Cardiac Arrest
This retrospective population-based cohort study uses linked administrative healthcare data from the Local Health Authority of Bologna (Italy) to describe the use of four classes of psychoactive drugs (opioids, antiepileptics…
- Conditions
- Wounds and Injuries, Out-of-Hospital Cardiac Arrest, Traumatic Brain Injury
- Trial name
- LIFT-C (NCT07882589)
- Testing
- Opioids (ATC N02A), Antiepileptics (ATC N03A), Antipsychotics (ATC N05A)
- Where
- 2 sites in Italy
- Volunteers
- 52,720 people
- Sponsor
- Azienda Usl di Bologna
Out-of-hospital Cardiac Arrest
German Cardiac Arrest Registry
In Germany, 70.000 to 100.000 patients suffer from out-of-hospital cardiac arrest (OHCA) every year. More than half of these are due to cardiac causes.
- Trial name
- G-CAR (NCT05142124)
- Where
- 25 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Leipzig Heart Science gGmbH
Hypoxemia, Arrhythmias
Differences in Morbidity Between a Necessity Endotracheal Suctioning Protocol Versus a Routine Endotracheal Suctioning
Morbidity frequency associated to a endotracheal suctioning is different between a necessity endotracheal suctioning protocol versus a routine endotracheal protocol.
- Conditions
- Hypoxemia, Arrhythmias, Cardiac Arrest, Ventilator Associated Pneumonia
- Trial name
- NCT01069185
- Testing
- Necessity endotracheal suctioning, Routine endotracheal suctioning
- Where
- Colombia
- Volunteers
- 92 people
- Sponsor
- Hospital Pablo Tobón Uribe
Out-of-Hospital Cardiac Arrest
Smartphone Video-assisted Advanced Life Support of Patients With Out-of-hospital Cardiac Arrest by EMS Under Physician Direction
Direct medical control using video conferencing capabilities of smartphones has never been conducted in out-of-hospital cardiac arrest patients.
- Trial name
- SWALS (NCT03041350)
- Testing
- Smartphone video-assisted ALS(advanced life support)
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Seoul National University Hospital
Cardiac Death, Cardiac Arrest
Quality of Cardiopulmonary Resuscitation Pre- and Intra Hospital
The survival after intrahospital cardiac arrest has been reported to 15%. In Norway this varies between 16 and 23%.). Many factors are associated with survival after cardiac arrest, both intra- and prehospital.
- Conditions
- Cardiac Death, Cardiac Arrest, Cardiac Arrhythmia, Cardiac Disease
- Trial name
- NCT04295291
- Volunteers
- 300 people
- Sponsor
- Ostfold University College