Clinical trials: In-Hospital Mortality
Life Quality, Hospital Mortality
Effect of Nutritional Support and Early Rehabilitation on Sepsis
Sepsis is a syndrome of life-threatening organ dysfunction caused by a dysregulated host response to infection.Acute catabolic response in critically ill patients struck by sepsis, manifested by massive protein breakdown in a…
- Trial name
- NUSPOTER (NCT05781971)
- Testing
- high protein, rehabilitation, standard protein
- Volunteers
- 1,600 people
- Sponsor
- Jinling Hospital, China
Acute Kidney Injury, Kidney Failure, Acute
Clinical Characteristics and In-Hospital Outcomes of Critically Ill Patients Receiving Hemodialysis or Continuous Venovenous Hemodiafiltration in the Emergency Department
This retrospective observational study aims to evaluate the clinical characteristics and in-hospital outcomes of critically ill adult patients who underwent hemodialysis (HD) or continuous venovenous hemodiafiltration (CVVHDF) in…
- Conditions
- Acute Kidney Injury, Kidney Failure, Acute, Kidney Failure
- Trial name
- NCT07765030
- Testing
- Hemodialysis (HD), Continuous Venovenous Hemodiafiltration (CVVHDF)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Antalya Health Sciences University
Cardiac Arrest, Perioperative Complication
The Factors Associated 30-day Mortality After Perioperative Cardiac Arrest in Adults Undergoing Non-cardiac Surgery.
Perioperative cardiac arrest (PCA) in patients undergoing noncardiac surgery is a rare but potentially catastrophic event associated with high mortality.
- Trial name
- NCT06712134
- Volunteers
- 105 people
- Sponsor
- Siriraj Hospital
Cardiogenic Shock, Microbial Colonization
Influence of Enteral Microbiome on Mortality of Patients With Cardiogenic Shock
Cardiogenic shock is associated with a high mortality. The microbiome is a double-edged sword which can convey protective and detrimental cardiovascular effects.
- Conditions
- Cardiogenic Shock, Microbial Colonization, Out-Of-Hospital Cardiac Arrest, Acute Heart Failure
- Trial name
- NCT06006754
- Testing
- Observational study
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital, Essen
Burn Injury, In-Hospital Mortality
Burn Mortality Prediction Scores
This retrospective observational cohort study evaluates hospitalized burn admissions treated at the Burn Center of Gaziantep City Hospital between October 2023 and February 2026.
- Trial name
- BURN-PRED (NCT07689890)
- Testing
- Retrospective Prognostic Score Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 1,082 people
- Sponsor
- Gaziantep City Hospital
Hip Fractures, In-hospital Mortality
Mortality and Predictors of In-hospital Mortality Among Geriatric Patients With Hip Fracture
To assess the incidence of in-hospital mortality among geriatric patients with hip fractures and to identify its potential predictors
- Trial name
- NCT07873918
- Volunteers
- 141 people
- Sponsor
- Assiut University
Perioperative/Postoperative Complications, Morbidity, Multiple
Machine Learning Modeling of Intraoperative Hemodynamic Predictors of Postoperative Outcomes
With population aging and limited resources, strategies to improve outcomes after surgery are ever more important. There is a limited understanding of what ranges of hemodynamic variables under anesthesia are associated with…
- Conditions
- Perioperative/Postoperative Complications, Morbidity, Multiple, Surgery, Anesthesia
- Trial name
- NCT04014010
- Testing
- Blood pressure, Heart rate, Use of hemodynamic medications (i.e. special medications for blood pressure)
- Volunteers
- 35,000 people
- Sponsor
- Janny Xue Chen Ke
Advance Care Planning
Quality Improvement Project for Advance Care Planning Tool in Hospital Medicine
Hospitalized patients and their families are often unprepared regarding end-of-life care. Even patients with high risk of mortality within the index admission or 30 days after admission often do not have clearly defined goals of…
- Trial name
- NCT04296136
- Testing
- Advance Care Planning Discussion
- Where
- United States
- Volunteers
- 743 people
- Sponsor
- Duke University
Appointments and Schedules, Outpatient Clinics, Hospital/Economics
Non Attendance at Scheduled Appointments as a Marker of Mortality and Hospital Admission
To evaluate the association of non attendance at scheduled appointments with visits in the emergency department, hospitalizations and mortality during one year follow up.
- Conditions
- Appointments and Schedules, Outpatient Clinics, Hospital/Economics, Emergency Department, Hospitalization
- Trial name
- NCT02210637
- Where
- Argentina
- Volunteers
- 177,083 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Volume Outcome Relationship Among COVID-19 Inpatients in US Hospitals
Hospital COVID-19 Surge and Associated Mortality Risk
A retrospective cohort study will be conducted using a large administrative database of U.S. hospitals to understand the volume-outcome relationship among patients hospitalized with COVID-19.
- Trial name
- NCT04688372
- Testing
- Surge Index
- Where
- United States
- Volunteers
- 144,116 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Intensive Care Unit Syndrome, Mechanical Ventilation Complication
Ketamine Infusion as Sedative Analgesic in Severe ARDS
To evaluate whether ketamine is a safe sedative-analgesic agent to be used in an intensive care unit (ICU) setting as compared to traditionally used agents such as propofol, opioids, and midazolam
- Conditions
- Intensive Care Unit Syndrome, Mechanical Ventilation Complication, Sedatives and Hypnotics Causing Adverse Effects in Therapeutic Use, Delirium
- Trial name
- KISS (NCT04818827)
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Interfaith Medical Center
Pneumonia, Ventilator-Associated
Comparison Between Two Methods of Oral Care on the Incidence of VAP
Patients on ventilator are in high risk to develop ventilator associated pneumonia (VAP). This acquired infection significantly increases morbidity and mortality of these patients.
- Trial name
- NCT00521677
- Testing
- Sage oral care, Traditional oral care
- Where
- Israel
- Volunteers
- 108 people
- Sponsor
- HaEmek Medical Center, Israel
Pancreatic Diseases
Influence of Hospital Volume on Mortality and Length of Hospital Stay After Pancreatic Resection in Switzerland
The effect of centralisation measures on the operative outcomes after pancreatic resection in Switzerland has not been highlighted yet.
- Trial name
- NCT07022639
- Testing
- Total pancreatectomy, Proximal pancreatectomy, Distal pancreatectomy
- Where
- Switzerland
- Volunteers
- 6,785 people
- Sponsor
- Cantonal Hospital of St. Gallen
Malnutrition
Effects of Nutritional Supplementation and Dietary Advice in Elderly Patients After Hospital Discharge.
The purpose of this study is to evaluate the effects of nutritional therapy in elderly malnourished patients. The hypothesises are that nutritional supplementation and dietary advice alone or in combination affects mortality…
- Trial name
- NCT01057914
- Testing
- Nutritional supplementation with a liquid formula, Dietary advice, Combination of supplement and dietary advice
- Where
- 5 sites in Sweden
- Volunteers
- 671 people
- Sponsor
- Uppsala University
Covid-19, Thromboembolic Events
Anticoagulant Therapy and 28-days Mortality in Critically Ill COVID-19 Patients
The aims of the study are to to associate anticoagulation (AC) regime with outcome in critically ill patients with Covid-19. This will be done by describe baseline characteristics and comorbidities before hospital admission…
- Conditions
- Covid-19, Thromboembolic Events, Bleeding
- Trial name
- NCT04412304
- Testing
- Dose of Tinzaparin or Dalteparin
- Where
- Sweden
- Volunteers
- 166 people
- Sponsor
- Karolinska Institutet
Hyperglycemia, Critically Ill Patients
Impact of 2 Blood Glucose Levels on Hospital Mortality in Patients Admitted in ICU
During hospitalization in the intensive care unit (ICU), the occurrence of a blood glucose imbalance is frequent and associated with increased mortality.
- Trial name
- INSUREA (NCT00591071)
- Testing
- Strict glycemic control, Conventional glycemic control
- Where
- 2 sites in France
- Volunteers
- 440 people
- Sponsor
- Poissy-Saint Germain Hospital
Detection of Different Prognostic Factors and Their Relation With the Outcome, Using New Protocol to Prove the Role of N-acetyl Cysteine and Adequate Supportive Measures in Aluminum Phosphide Poisoning
Supportive Measures in Treatment of Aluminum Phosphide Poisoning
Aluminum phosphide poisoning (ALP) is a global public health problem, and self-poisoning accounts for one-third of the world's suicide rate.
- Trial name
- NCT03879356
- Testing
- N-acetyl cysteine
- Volunteers
- 44 people
- Sponsor
- Assiut University
Paediatric Surgery, Perioperative/Postoperative Complications
An African, Multi-centre Evaluation of Patient Care and Clinical Outcomes for Paediatric Patients Undergoing Surgery
Access to safe surgery is a basic human right. This is highlighted by the work of the Lancet Commission on Global Surgery. There is a large burden of surgical disease in the paediatric surgical population with a large unmet need.
- Conditions
- Paediatric Surgery, Perioperative/Postoperative Complications, Perioperative Outcomes, Hospital Mortality
- Trial name
- ASOS-Paeds (NCT05061407)
- Where
- 2 sites in South Africa, Sudan
- Volunteers
- 8,625 people
- Sponsor
- University of KwaZulu
Critical Illness
Lormetazepam Versus Midazolam in Critically Ill Patients: a Retrospective Cohort Trial
The aim of this retrospective cohort study is to evaluate the effect of lormetazepam versus midazolam on hospital mortality, intensive care unit outcomes and sedation management.
- Trial name
- RetroLoveMi (NCT04408911)
- Testing
- Midazolam vs. Lormetazepam
- Volunteers
- 3,314 people
- Sponsor
- Charite University, Berlin, Germany
Neonatal Morbidity and Mortality, Intrauterine Growth Disorders (IUGR and Macrosomia)
Analysis on the Health of Newborns in Three Hospitals, 2008-2024
The objective of this observational study is to analyze the factors associated with neonatal morbidity and mortality in three hospitals in Quito, Ecuador, from January 2008 to June 2024.
- Conditions
- Neonatal Morbidity and Mortality, Intrauterine Growth Disorders (IUGR and Macrosomia), Prematurity Complications, Neonatal Infections
- Trial name
- NCT06758622
- Where
- Ecuador
- Volunteers
- 40,000 people
- Sponsor
- HOSPITAL GINECO OBSTETRICO ISIDRO AYORA