Clinical trials: In-Vitro Fertilization
Infertility, Female, First Trimester Spontaneous Abortion
Determination of Circulating Placental Biomarkers Levels to Predict the Pregnancy Outcome of First Trimester After IVF.
This study will assess the predictive potential of circulating placental biomarkers for spontaneous miscarriage within the following month in an IVF setting.
- Trial name
- NCT04387994
- Testing
- Blood samples collection
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Infertility
In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization
Methods of infertility treatment may involve in vitro fertilization or IVF. Though effective, IVF is complex and expensive. Methods using no gonadotropin hormone stimulation of the ovaries are being compared to mild stimulation…
- Trial name
- IVM vs IVF (NCT00867763)
- Testing
- In vitro maturation and in vitro fertilization, Low doses of gonadotropin stimulation.
- Where
- 2 sites in United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Batzofin Fertility Services
In Vitro Fertilisation (IVF) Treatment
Effect of Oxytocin Antagonist on Reduction of Uterine Contractions
The main purpose of this clinical research trial was to evaluate the effects of barusiban compared to placebo on uterine contractions on luteal phase uterine contractions in oocyte donors supplemented with progesterone.
- Trial name
- EFFORT (NCT01043120)
- Testing
- Barusiban
- Where
- 5 sites in Belgium, Czechia and 1 more
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
GDM, Insulin Resistance
In Vitro Fertilization Impact on Metabolic Parameters
A quantitative prospective cohort study will be conducted, where blood samples will be collected at different timings during the IVF protocol, to assess the impact of fertility medications on metabolic parameters of patients…
- Conditions
- GDM, Insulin Resistance, Glucose Intolerance, PCOS
- Trial name
- IVF (NCT03426228)
- Testing
- HbA1C
- Where
- United Arab Emirates
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Acupuncture, in Vitro Fertilization
The Differences of Oocyte Maturation, Granulosa Cell Apoptosis Index Between Electroacupuncture And Sham Groups IVF
Interventional studies compared electroacupuncture group versus sham electroacupuncture group to granulosa cell apoptosis index, oocyte maturation, GDF9 and BMP15 levels, and fertilization rate in in vitro fertilization program
- Conditions
- Acupuncture, in Vitro Fertilization, BCL2 Gene mRNA Overexpression, Oocyte Maturation
- Trial name
- NCT03627533
- Testing
- Electroacupuncture
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
in Vitro Fertilization
Follicular Fluid Sialic Acid Levels in IVF Cycles
This cross-sectional study was conducted at the Reproductive Endocrinology and Invitro Fertilization (REI) unit of our hospital, following the approval of the hospital's ethics committee.
- Trial name
- NCT03745027
- Testing
- in vitro fertilization
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Mood Disorders
Gonadal Steroid Manipulation and Personality Characteristics: Association With Mood Fluctuations and in Vitro Fertilization (IVF) Outcomes
The current study's primary aim is to investigate the association between neuroendocrine fluctuations and mood disorders by monitoring mood states over distinct hormonal phases during in-vitro-fertilization (IVF) treatment.
- Trial name
- IVF (NCT01032421)
- Testing
- IVF procedure
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Embryo Transfer, Fertilization in Vitro
Does Sexual Intercourse Affect the Outcomes of Frozen-thawed Embryo Transfer?
The goal of this clinical trial is to test whether sexual intercourse the night after embryo transfer affects thawed embryo implantation rates.
- Conditions
- Embryo Transfer, Fertilization in Vitro, Coitus
- Trial name
- NCT06134609
- Testing
- Sexual intercourse
- Where
- Israel
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility
In Vitro Maturation (IVM) of Human Oocytes
The objectives of this study are to evaluate the clinical efficacy of Natural in vitro Fertilization and in vitro maturation.
- Trial name
- IVM (NCT01550861)
- Testing
- in vitro maturation, Polar Body Biopsy with preimplantation genetic screening
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Women Suffering From Unilateral or Bilateral Tubal Occlusion Due to Hydrosalpinx
Use of Adiana Tubal Occlusive Devices in Women With Hydrosalpinx Prior to In Vitro Fertilization
A condition called hydrosalpinx occurs when one or both of the fallopian tubes is blocked with fluid. The fluid can leak into the tube and the uterus.
- Trial name
- NCT01224080
- Testing
- Adiana placement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Reproductive Science Center
Infertility, in Vitro Fertilization
Ultrasound Guided Embryo Transfer: Abdominal Versus Transvaginal, a RCT
Ultrasound (US) guided embryo transfer (ET) appears to improve pregnancy outcomes in IVF-ET. Most reports are done using a transabdominal (TAS) approach, in contrast to a transvaginal ultrasound (TVS) which does not require a…
- Trial name
- NCT00682071
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Infertility
Study to Estimate Seedchrony's Predictive Capacity in the Success of Embryo Implantation.
In Vitro Fertilization (IVF) success is below 40%, with Embryo Transfer the leading cause of IVF failure. This clinical investigation aims to evaluate if the levels of an intrauterine biomarker dissolved in the uterine fluid…
- Trial name
- Seedchrony02 (NCT06259084)
- Testing
- Seedchrony
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Manina Medtech
Infertility
Protocol to Minimize Injections and Blood Draws for Women Undergoing in Vitro Fertilization
The purpose of the study is to evaluate the safety and efficacy of nasal gonadotropins (Menopur) in women undergoing IVF. The purpose of this study is also to report and monitor any and all side effects of the nasal Menopur.
- Trial name
- NCT02865681
- Testing
- Menopur, Synarel, HCG trigger
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- New Hope Fertility Center
Male Infertility
Proposed Research Protocol For Male Infertility
The purpose of this experiment is to test the feasibility of a minimally interventionist protocol for young couples with male factor infertility, which addresses the cause of infertility for these couples which is the inability…
- Trial name
- NCT01255397
- Testing
- Male Infertility Protocol
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Infertility, Female
Comparison of in Vitro Fertilization Rates of Oocytes and Embryo Development Using Two Techniques of Semen Processing
The investigators propose to assess one method of sperm selection based on the characteristics of spermatozoa recently introduced: Sperm Selection Assay, which used a gradient of concentration of progesterone to act as…
- Trial name
- NCT03186170
- Testing
- SSA sperm selection
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
IVF, Body Weight
Nutritional Status of Women Undergoing in Vitro Fertilization
Infertility affects around 15 % of couples in their reproductive years. Even though the use of assisted reproductive technologies (ART) in aforementioned couples is increasing, their success rate is still relatively low.
- Conditions
- IVF, Body Weight, Nutrient Deficiency, Dietary Vitamin B12 Deficiency Anemia
- Trial name
- NCT05865015
- Where
- 2 sites in Slovenia
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Poor Ovarian Response, Ovarian Insufficiency
Improving in Vitro Fertilization in Women With Poor Ovarian Response
Improving the results of in vitro fertilization in women with poor ovarian response and early ovarian insufficiency
- Trial name
- NCT04024722
- Testing
- In Vitro Fertilization
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Primary Female Infertility, Secondary Female Infertility
Effect of Traditional Chinese Medicine on In Vitro Fertilization (IVF) Success Rates
The purpose of this study is to determine the value of combining Traditional Chinese Medicine (TCM) Protocols including acupuncture with In Vitro Fertilization (IVF).
- Trial name
- TCM-P002 (NCT01331395)
- Testing
- Traditional Chinese Medicine
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Pacific Fertility Center
in Vitro Fertilization
Improvement of in Vitro Fertilization Implantation by Soluble CD146 Dose in Embryonic Culture Environment
The study of implantation potential of the embryo stay a priority in In Vitro Fertilization (IVF). Indeed, the selection of embryos to transfer is actually based in routine check on morphologic criteria, approved by literature…
- Trial name
- AMIFIV (NCT03785119)
- Where
- France
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Healthy
Effect of Body Composition and Metabolism on Oocyte Gene Expression
The investigators will test the hypothesis that obese women have a unique oocyte gene expression profile that differs significantly from that of normal weight women.
- Trial name
- NCT01480024
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute