Clinical trials: In-vitro Fertilization
Children Born After Assisted Reproductive Technologies, Health Status
Health Status of Children Born After Assisted Reproductive Technologies
The goal of this observational study is to study the features of psychophysical development and the morbidity patterns of children born after assisted pregnancy, and to identify the connection with the health status of mothers…
- Conditions
- Children Born After Assisted Reproductive Technologies, Health Status, Child Development
- Trial name
- NCT06094998
- Testing
- hemogram examination
- Where
- Kazakhstan
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Kazakhstan's Medical University "KSPH"
Anxiety, Pregnancy Outcomes
Effect of Breathing Exercises on Embryo Transfer Outcomes
Breathing exercises are being used in many different clinical issues in the area of medicine. Also in gynecological practice, especially during labor, breathing exercises are encouraged by health professionals to aid the…
- Trial name
- BreathIVF (NCT07109544)
- Testing
- Breathing Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eurofertil IVF Health Center
IVF
Comparative Study Between Fresh and Frozen Embryo Transfer in PCOS Patients Undergoing IVF Treatment
The objective of our study is to compare in vitro fertilization (IVF) outcomes between fresh embryo transfer (ET) and frozen-thawed ET in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT05167838
- Testing
- fresh embryo transfer, Frozen embryo transfer
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infertility, Female
The Effect of Progressive Muscle Relaxation and Laughter Therapy on Women Undergoing In Vitro Fertilization
Purpose: This study was aimed to evaluate the effect of progressive muscle relaxation exercises and laughter therapy on the mental health and treatment outcomes of women receiving IVF treatment.
- Trial name
- NCT04782882
- Testing
- Progressive muscle relaxation+laughter therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Poor Responders Undergoing IVF
The Comparison of Effect of Four Different Treatment Protocols on IVF Outcomes in Poor Responders Undergoing in Vitro Fertilization.
The comparison of effect of four different treatment protocols: Antagonist/letrozole protocol, microdose flare-up protocol, Antagonist/clomiphene protocol, Antagonist on IVF outcomes in poor responders undergoing in vitro…
- Trial name
- NCT01948804
- Testing
- GnrH Antagonist/letrozole protocol (Cetrotide; serono + Femara; Novartis Pharma AG), microdose flare-up protocol (Lucrin; Abbott + Gonal F, Serono), Antagonist/clomiphene protocol (Cetrotide; serono + Klomen, Kocak pharma)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pınar Özcan Cenksoy
Minor Intra-uterine Abnormalities
The Impact of Treating Minor Uterine Cavity Abnormalities Diagnosed by Office Hysteroscopy in Unselected In Vitro Fertilization (IVF) Cases
This is a comparative, controlled trial to evaluate the impact of treating undetected, asymptomatic, predefined minor uterine cavity abnormalities on the success of IVF treatment.
- Trial name
- NCT00830401
- Testing
- Treatment of predefined abnormality by hysteroscopic surgery, Ofloxacinum/Doxycycline
- Where
- Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Infertility, Female, Infertility, Male
Oral Dydrogesterone vs. Micronized Vaginal Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer Cycles
The aim of this randomized controlled trial is to compare the efficacy of oral dydrogesterone vs. micronized vaginal progesterone for luteal phase support in frozen-thawed embryo transfer cycles.
- Conditions
- Infertility, Female, Infertility, Male, Embryo Transfer, Fertilization in Vitro
- Trial name
- NCT04124913
- Testing
- Dydrogesterone 10 MG Oral Tablet, Progesterone Vaginal Gel [Crinone]
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Memorial Sisli Hospital, Istanbul
Pregnancy, Live Birth
Folic Acid and Zinc Supplementation Trial (FAZST)
The overarching goal of this trial is to determine if an intervention comprising folic acid and zinc dietary supplementation improves semen quality and indirectly fertility outcomes (i.e., live birth rate) among couples trying to…
- Conditions
- Pregnancy, Live Birth, Spontaneous Abortion
- Trial name
- FAZST (NCT01857310)
- Testing
- 5 mg folic acid and 30 mg elemental zinc
- Where
- 4 sites in United States
- Volunteers
- 2,370 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
in Vitro Fertilization
Embryo Transfer With Self-spent Culture Medium
Embryo Transfer With Self-spent Culture Medium or new Culture Medium in Vitro Fertilization - Embryo Transfer Process, to analyze which way can improve clinical pregnancy outcomes, is there a significant difference between the…
- Trial name
- NCT03728140
- Testing
- Self-spent Culture Medium
- Where
- China
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Bin Wu
Maternal Cardiometabolic Health, Infertility
St Mary's Assisted Reproductive Technology and Cardiometabolic Health: Modifiable Targets for Multimorbidity Prevention (START-HEALThY)
The main causes of death in women are conditions affecting the heart and blood vessels (cardiovascular disease, CVD). Women who have difficulties getting pregnant (infertility) may be at increased risk, but the reasons for this…
- Conditions
- Maternal Cardiometabolic Health, Infertility, Assisted Reproductive Technology, Cardiovascular Health
- Trial name
- START-HEALThY (NCT07173569)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Endometrium
Endometrial Dating by Ex-vivo Imaging of Endometrial Biopsies of In-vitro Fertilization Candidate Participants
To evaluate the correlation between cycle day determination by clinical signs, study participant testimony, endometrium histopathology biopsy and ex-vivo imaging of the uterus endometrium.
- Trial name
- NCT04288843
- Where
- 2 sites in Israel
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Fertigo Medical Ltd
Ovarian Stimulation
Clomiphene Citrate (CC)/Gonadotropin/Gonadotropin Releasing Hormone (GnRH) Antagonist Versus Gonadotropin/GnRH Agonist
Objective: To compare the efficacy of using mild ovarian stimulation protocol and conventional stimulation protocol in IVF outcome. Design: Prospective randomized trial Setting: University IVF setting.
- Trial name
- NCT00830492
- Testing
- clomiphene citrate, Ultrasound, GnRH antagonist
- Where
- Iran
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
Infertility
Rekovelle PK Trial in Chinese Women
FE 999049 is a gonadotropin preparation containing recombinant human follicle stimulating hormone (rhFSH) under development by Ferring Pharmaceuticals.
- Trial name
- NCT04150861
- Testing
- Follitropin Delta
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Women Suffering From Unilateral or Bilateral Tubal Occlusion Due to Hydrosalpinx
Use of Adiana Tubal Occlusive Devices in Women With Hydrosalpinx Prior to In Vitro Fertilization
A condition called hydrosalpinx occurs when one or both of the fallopian tubes is blocked with fluid. The fluid can leak into the tube and the uterus.
- Trial name
- NCT01224080
- Testing
- Adiana placement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Reproductive Science Center
Poor Response to Ovulation Induction, Infertility, Female
Autologous Platelet Rich Plasma Intraovarian Infusion for Poor Responders
Autologous platelet rich plasma (PRP) intraovarian infusion may improve ovarian response to controlled ovarian stimulation as well as the hormonal profile of poor ovarian response infertile women subjected to intracytoplasmic…
- Conditions
- Poor Response to Ovulation Induction, Infertility, Female, Ovarian Insufficiency, Ovarian Failure
- Trial name
- PRPPOR (NCT05181748)
- Testing
- Autologous platelet rich plasma
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Infertility, Oocytes
Efficacy of a Simulator Based (PickUpSimTM) Residents' Training Program for Oocyte Retrievals
Simulation is an educational approach that has recently found an application in healthcare.acquire. Angers university hospital has decided to acquire, in December 2016, the high-fidelity Oocyte Pick up (OPU) simulator…
- Conditions
- Infertility, Oocytes, Fertilization in Vitro
- Trial name
- NCT03700255
- Testing
- PickUpSimTM simulation training program
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Infertility
Study to Estimate Seedchrony's Predictive Capacity in the Success of Embryo Implantation.
In Vitro Fertilization (IVF) success is below 40%, with Embryo Transfer the leading cause of IVF failure. This clinical investigation aims to evaluate if the levels of an intrauterine biomarker dissolved in the uterine fluid…
- Trial name
- Seedchrony02 (NCT06259084)
- Testing
- Seedchrony
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Manina Medtech
Reproductive Techniques, Assisted, DNA Methylation
First Live Birth Rate With eSET After Preimplantation Methylome Screening (PIMS) Versus Conventional In-vitro Fertilization
To determine whether using DNA methylome to select embryos can increase the live birth rate.
- Trial name
- NCT05442125
- Testing
- Using DNA methylome to select embryos, Using morphologic score to select embryos
- Where
- 28 sites in China, Thailand
- Volunteers
- 1,146 people, healthy volunteers welcome
- Sponsor
- Shandong University
Poor Ovarian Response, Ovarian Insufficiency
Improving in Vitro Fertilization in Women With Poor Ovarian Response
Improving the results of in vitro fertilization in women with poor ovarian response and early ovarian insufficiency
- Trial name
- NCT04024722
- Testing
- In Vitro Fertilization
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
in Vitro Fertilization
The Role of DNA Damage of Granulosa Cell on Oocyte Quality and in Vitro Fertilization Outcome
Deoxyribonucleic acid (DNA) damage of granulosa cells obtained during oocyte retrieval will be evaluated by comet assay in unexplained infertile patients undergoing in vitro fertilization (IVF) treatment.
- Trial name
- NCT03345030
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University