Clinical trials: Incision Infection
Cesarean Section, Endometritis
Vaginal Cleansing at Cesarean Delivery to Reduce Infection: A Randomized, Controlled Trial
The objective of the project is to find out whether cleansing the vagina before a cesarean delivery decreases the risk of complications and infections after having the baby.
- Conditions
- Cesarean Section, Endometritis, Surgical Wound Infection
- Trial name
- NCT00386477
- Testing
- Vaginal cleansing before cesarean delivery
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Indiana University
Spinal Deformity
Incisional Negative Pressure Wound Therapy
The purpose of this study is to evaluate the outcome of incisional negative pressure wound therapy in preventing surgical site infections and wound complications (dehiscence) in high-risk patients undergoing complex spinal…
- Trial name
- NCT01759381
- Testing
- Negative pressure wound therapy (NPWT)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Duke University
Wound Infections
Cubicin(R) for Complicated Post-surgical Wound Infections
The purpose of the study is to describe the clinical efficacy of CUBICIN therapy in patients with superficial and deep post-surgical Gram-positive wound infections
- Trial name
- PSW (NCT00651131)
- Testing
- daptomycin
- Volunteers
- 69 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical
Effect of Continuous Versus Interrupted Suturing on Wound Dehiscence and Infection After Abdominal Surgery
The goal of this clinical trial is to learn whether the type of suturing technique used to close the abdomen after exploratory laparotomy affects the rate of wound complications.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical, Dehiscence of Laparotomy Wound, Suture, Interrupted
- Trial name
- NCT07241507
- Testing
- Continuous suturing, Interrupted suturing
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Allama Iqbal Teaching Hospital
Postoperative Wound Infection
Effects of Triclosan-coated Sutures in Cardiac Surgery
The purpose of this study is to assess if triclosan-coated sutures reduces wound infections after saphenous vein harvesting in CABG patients.
- Trial name
- NCT01212315
- Testing
- Triclosan coated sutures
- Where
- Sweden
- Volunteers
- 392 people
- Sponsor
- Sahlgrenska University Hospital
Surgical Site Infection
Assessment of the Efficacy of ChatGPT in Detecting Surgical Site Infections Following Elective Colorectal Surgery
Epidemiological surveillance is one of the eight core components of the World Health Organization Infection Prevention and Control Programmes. These include surveillance programmes for surgical site infection (SSI).
- Trial name
- ChatCCR (NCT06556017)
- Testing
- Diagnosis of SSI
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Hospital de Granollers
Surgical Site Infection, Surgical Wound
Triclosan-antibacterial Sutures Efficacy on the Incidence of Surgical Site Infection in Clean-contaminated Wounds
Comparing the incidence of SSI in cases using coated Polyglactin 910 suture with Triclosan and cases using Polyglactin 910 suture without Triclosan in clean-contaminated wound surgery
- Conditions
- Surgical Site Infection, Surgical Wound, Surgical Wound Infection
- Trial name
- NCT04256824
- Testing
- coated vicryl plus, Vicryl
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- ClinAmygate
Surgical Site Infection, Microbial Colonization
Broad-spectrum Antibiotic Prophylaxis in Tumor and Infected Orthopedic Surgery
The perioperative antibiotic prophylaxis is evidence-based in orthopedic surgery. While its duration ranges from a single dose to three doses throughout the world, the choice of the prophylactic agents is undisputed.
- Conditions
- Surgical Site Infection, Microbial Colonization, Antibiotic Resistant Infection
- Trial name
- BAPTIST (NCT05502380)
- Testing
- Standard antibiotic prophylaxis
- Where
- Switzerland
- Volunteers
- 1,100 people
- Sponsor
- Balgrist University Hospital
Inguinal Hernia Unilateral
STAPLES VERSUS SUTURES FOR MESH FIXATION IN LICHTENSTEIN HERNIOPLASTY: A RANDOMIZED CONTROLLED TRIAL EVALUATING POSTOPERATIVE OUTCOMES IN INGUINAL HERNIA PATIENTS
The study is aimed at comparing postoperative complications between two different techniques of mesh fixation in lichtenstein inguinal hernia repair.
- Trial name
- NCT07627425
- Testing
- Mesh fixation with Staples, Mesh Fixation with Sutures
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Huzaif Saeed Khan
Postoperative Surgical Site Infection
Negative Pressure Incision Management System in Infrainguinal Vascular Surgery
Negative pressure wound therapy (NPWT) has been used in treating postoperative SSI with encouraging results and is now an accepted element in the arsenal of tools for treating these complications.
- Trial name
- NCT03395613
- Testing
- NPWT
- Where
- Sweden
- Volunteers
- 118 people
- Sponsor
- Karolinska University Hospital
Surgical Site Infection
Pharmacokinetic Study of Vancomycin, Clindamycin And/or Gentamicin Administration During Surgery Using a Microdialysis Procedure
The surgical site infection is one of the most important causes of postoperative morbidity. The appropriate antibiotic prophylaxis is one of the most effective way to prevent surgical site infections.
- Trial name
- NCT03845790
- Testing
- Blood and microdialysis samples
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Poitiers University Hospital
Incisional Hernia of Anterior Abdominal Wall, Dehiscence Wound
Prevention of Incisional Hernia With Mesh-suture at Umbilical Trocar Site.
Incisional hernia related to the umbilical trocar site is probably the most frequent complication after laparoscopic surgical procedures.
- Conditions
- Incisional Hernia of Anterior Abdominal Wall, Dehiscence Wound, Wound Infection
- Trial name
- INDURATE (NCT06251583)
- Testing
- duramesh suture
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- Miguel A ngel Garci-a Urena
Colorectal Surgery
Mechanical Bowel Prep Randomized Study
Following colon surgery, surgical site infection (SSI) is the most common complication and leads to longer recovery time for patients and increased health care costs.
- Trial name
- NCT04931173
- Testing
- IVA+OA versus IVA+MBP+OA
- Volunteers
- 1,062 people
- Sponsor
- Mount Sinai Hospital, Canada
Incisional Ventral Hernia, Recurrent Ventral Hernia
Modified "Open Intraperitoneal Mesh" Technique of Incisional Ventral Hernia Repair
Ventral hernias, primary and recurrent, are major surgical challenge. We aim to investigate efficacy of modified technique of ventral hernias repair: an "open intraperitoneal mesh" technique.
- Trial name
- NCT01953302
- Testing
- modified "open mesh technique"
- Where
- Croatia
- Volunteers
- 124 people
- Sponsor
- Varazdin General Hospital
Surgical Site Infection
Environmental Risk Factors of Mesh Infection After Abdominal Wall Hernia Repair
Mesh infection is the main complication in abdominal hernia repair. In case of infection, a conservative management of mesh is not always possible.
- Trial name
- NCT04174976
- Testing
- wall hernia repair
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Cesarean Section
The Effect of Amniotic Membrane Application on Post-Cesarean Wound Healing and Cosmetic Outcomes
This clinical trial evaluates the effectiveness of amniotic membrane application during cesarean delivery in reducing post-surgical complications and improving wound healing and cosmetic outcomes in women aged 18-40 undergoing…
- Trial name
- Amniotic Membr (NCT06770946)
- Testing
- Amniotic Membrane Application
- Where
- Turkey (Türkiye)
- Volunteers
- 372 people
- Sponsor
- Yuzuncu Yil University
Colorectal Cancer
Standard Versus Advanced Antimicrobial Dressing Containing Ionic Silver Following Colorectal Cancer Surgery
The purpose of this study is to evaluate the efficacy of treatment with hydrofibre dressing in comparison with the efficacy of standard dressing in terms of prevalence of surgical site infections (SSI) in patients who underwent…
- Trial name
- AM (NCT00981110)
- Testing
- AQUAGEL Ag Hydrofiber Wound Dressing, Mepore Self-adhesive absorbent dressing
- Where
- 2 sites in Italy
- Volunteers
- 120 people
- Sponsor
- European Institute of Oncology
Breast Cancer
Does a Preoperative Prophylactic Antibiotic Reduce Surgical Site Infection Following Wire-localized Lumpectomy
Background: Data on the benefits of preoperative prophylactic antibiotics for breast surgery are conflicting and there is no guideline for their use for wire-localized lumpectomy.
- Trial name
- NCT04818931
- Testing
- Cefazolin Injection
- Where
- Canada
- Volunteers
- 326 people
- Sponsor
- CHU de Quebec-Universite Laval
Surgical Site Infection
SMS-Based Follow-Ups to Improve Post-Discharge Surgical Outcomes
The purpose of this study is to determine whether low-cost Short Message Service (SMS)-based follow-up medication reminders and surveys for surgical site infection (SSI) reporting can improve outcomes by increasing medication…
- Trial name
- NCT03161262
- Testing
- SMS-based reminders
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Emory University
Surgical Site Infection Following Cesarean Delivery
Comparison of Surgical Skin Preps During Cesarean Deliveries
In women that undergo non-emergency cesarean delivery, we are comparing the skin preparation solutions for best outcome of surgical site infection.
- Trial name
- NCT01870583
- Testing
- Iodine povidone, Chlorhexidine, Combination iodine and chlorhexidine
- Where
- 2 sites in United States
- Volunteers
- 1,404 people
- Sponsor
- Montefiore Medical Center