Clinical trials: Incisional Hernia of Midline of Abdomen
Open Midline Laparotomy
Prophylactic Reinforcement of Ventral Abdominal Incisions Trial
This trial is being conducted to evaluate the efficacy of Phasix™ Mesh implantation at the time of midline fascial closure compared to primary suture closure in preventing a subsequent incisional hernia in subjects at risk for…
- Trial name
- PREVENT (NCT03911700)
- Testing
- Phasix™ Mesh
- Where
- 32 sites in United States, Austria and 3 more
- Volunteers
- 477 people
- Sponsor
- C. R. Bard
Incisional Hernia After Midline Laparotomy, Colorectal Cancer
A One-year Follow-up of Incisional Hernia Formation Between Device Assisted and Manual Laparotomy Closure
The study compares one-year incisional hernia formation between two cohorts of patients that underwent open surgery for colorectal diseases.
- Trial name
- NCT07766044
- Testing
- Device assisted laparotomy closure, Manual laparotomy closure
- Where
- Sweden
- Volunteers
- 218 people
- Sponsor
- Suturion AB
Incisional Hernia of Midline of Abdomen
Barbed Suture for Emergency Midline Laparotomy Closure
Urgency surgeries are often performed in a stressful setting with critical patient involved. In this context, laparotomy closure can sometimes be the most neglected part of the procedure.
- Trial name
- BAROTOMY (NCT05351970)
- Testing
- Barbed
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Hernia, Ventral
Endoscopic Mini/Less Open Sublay(EMILOS) Repair
Ventral hernias in the midline of the abdominal wall are one of the most frequent diseases in general and visceral surgery worldwide. The optimal operative technique is still in discussion.
- Trial name
- EMILOS (NCT05912868)
- Testing
- Endoscopic Mini/Less Open Sublay Repair
- Where
- 3 sites in Germany
- Volunteers
- 174 people
- Sponsor
- Diakonie-Klinikum Stuttgart
Incisional Hernia of Midline of Abdomen
Open Vs. Endoscopic Transversus Abdominis Release Trial
This study aims to comparatively evaluate the early and long-term results of open and endoscopic TAR procedure for large midline incisional ventral hernias.
- Trial name
- NCT06195332
- Testing
- open TAR, endoscopic TAR
- Where
- Russia
- Volunteers
- 36 people
- Sponsor
- City Clinical Hospital No.1 named after N.I. Pirogov
Incisional Hernia of Midline of Abdomen, Surgical Wound
Onlay Mesh in Abdominal Aortic Aneurysm Repair.
The aim of the study was to compare the incidence of IH after abdominal aortic aneurysm (AAA) open repair according to the abdominal wall closure technique used.
- Trial name
- NCT07416422
- Testing
- Abdominal Ultrasound or computed tomography
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Incisional Hernia, Incisional Hernia of Midline of Abdomen
Mesh Augmented Reinforcement of Abdominal Wall Suture Line to Limit the Rate of Incisional Hernia Occurrence
The purpose of this prospective, pivotal, multi-center, single-arm, pre-market, investigational clinical study is to assess the safety and performance of Deternia™ Self-Gripping Resorbable Mesh when used for suture line…
- Conditions
- Incisional Hernia, Incisional Hernia of Midline of Abdomen, Midline Laparotomy
- Trial name
- MARS (NCT05424484)
- Testing
- Self-Gripping Resorbable Mesh
- Where
- 13 sites in Croatia, Germany and 3 more
- Volunteers
- 123 people
- Sponsor
- Medtronic - MITG
Incisional Hernia Occurence
Primary Mesh Closure of Abdominal Midline Wounds
Incisional hernia is the most frequently seen long term complication in surgery causing much morbidity and even mortality in patients.
- Trial name
- PRIMA (NCT00761475)
- Testing
- mesh supported closure, primary closure
- Where
- 12 sites in Austria, Germany and 1 more
- Volunteers
- 480 people
- Sponsor
- Erasmus Medical Center
Hernia, Ventral, Hernias Intestinal
Optimization of Surgical Treatment of Patients With Incisional Ventral Hernias
The goal of our work of optimization of the treatment of postoperative hernias is to improve the results of treatment of patients with median and median-lateral postoperative hernias of medium (W2) and large (W3) sizes by…
- Conditions
- Hernia, Ventral, Hernias Intestinal, Hernia Abdominal Wall
- Trial name
- NCT05734222
- Testing
- A new method of repair of the abdominal wall of mid-lateral postoperative ventral hernias
- Where
- Russia
- Volunteers
- 110 people
- Sponsor
- Samara State Medical University
Incisional Hernia/Prevention and Control, Surgical Site Infection (SSI)
Comparison of Small-bite Versus Conventional Midline Fascial Closure in Abdominal Surgeries
This study investigates how different incision and fascial closure (suture) techniques used in abdominal surgery are associated with the development of incisional hernia, a common long-term complication after laparotomy.
- Trial name
- NCT07340918
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Incisional Hernia of Midline of Abdomen
Algorithm for Prophylactic Mesh Use in Emergency Laparotomy.
Use of informed algorithm for patients selection of prophylactic mesh aplication after midline laparotomy in emergency surgery.
- Trial name
- NCT04808063
- Testing
- Prophylactic mesh implantation
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital del Mar
Chronic Pain, Wound Dehiscence
Comparing Polyglactin vs Polypropylene Sutures for Rectus Sheath Closure
This randomized controlled trial aims to compare the outcomes of Polyglactin (Vicryl) versus Polypropylene (Prolene) sutures for rectus sheath closure in patients undergoing midline laparotomy.
- Conditions
- Chronic Pain, Wound Dehiscence, Surgical Site Infection (SSI), Incisional Hernia
- Trial name
- PolySuture (NCT07280975)
- Testing
- Polyglactin 910 (Vicryl) Suture, Polypropylene (Prolene) Suture
- Where
- Pakistan
- Volunteers
- 156 people
- Sponsor
- Lady Reading Hospital, Pakistan
Incisional Hernia, Abdominal Aortic Aneurysm
Aneurysma Hernia Study - Incidence of Incisional Hernias After Abdominal Aortic Aneurysm Repair
Principles= Prevention of incision hernias by primary closure of mid line laparotomies with the best-evidenced suture techniques.
- Trial name
- АНЕУРИЗМА (NCT02012270)
- Testing
- PRINCIPLES technique, Conventional group
- Where
- 2 sites in Poland, Serbia
- Volunteers
- 240 people
- Sponsor
- Igor Koncar
Hernia, Ventral, Body Image
Functional Outcome After Incisional Hernia Repair: Open Versus Laparoscopic Repair
Background: Midline incisional hernia is reported from 0,5 to 11% after abdominal operations. Primary repair without mesh reinforcement is almost abandoned because of high recurrence rates (24 to 46%).
- Conditions
- Hernia, Ventral, Body Image, Respiratory Function Tests, Quality of Life
- Trial name
- GINCISHERNIA (NCT00625053)
- Testing
- Laparoscopic repair, Open midline incisional hernia repair
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Geneva
Incisional Hernia of Midline of Abdomen
Laparoscopic IPOM Plus vs. eTEP Trial
The survey will compare primary and secondary outcomes of laparoscopic intraperitoneal onlay mesh (IPOM plus) and extended totally extraperitoneal (eTEP) repair for incisional hernia.
- Trial name
- NCT05528107
- Testing
- Lap IPOM plus, eTEP
- Where
- Russia
- Volunteers
- 72 people
- Sponsor
- City Clinical Hospital No.1 named after N.I. Pirogov
Abdominal Aortic Aneurysm, Morbid Obesity
Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH)
The aim of the study is to describe the effectiveness of Optilene® Silver Mesh Elastic on prevention of surgical site infection (SSI) at 6 months follow-up in patients undergoing urgent laparotomy by collecting clinical data on…
- Trial name
- SSIHLVER (NCT06547138)
- Testing
- Prophylactic mesh
- Where
- 5 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Aesculap AG
Wound Complication
Comparing Wound Complications After Elective Abdominal Surgery Using Two Closure Techniques
Wound complications, increased hospital stays and post-operative morbidity are all common following abdominal surgery. Abdominal closure complications are strongly associated with the closure technique and material used.
- Trial name
- COFACTOR (NCT03527433)
- Testing
- New closure technique
- Where
- Lebanon
- Volunteers
- 274 people
- Sponsor
- American University of Beirut Medical Center
Incisional Hernia After Midline Laparotomy, Quality of Life (QOL)
NoPro - Norwegian Hernia Prophylaxis Study
A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh.
- Conditions
- Incisional Hernia After Midline Laparotomy, Quality of Life (QOL), Burst Abdomen, Surgical Site Infections
- Trial name
- NoPro (NCT06858020)
- Testing
- Prophylactic polypropylene onlay mesh
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sykehuset Innlandet HF
Hernia Incisional, Suture Materials
Fascial Abdominal Closure Evaluation
FACE (Fascial Abdominal Closure Evaluation) Trial is a prospective, single center, open-label, randomized trial of Duramesh versus PDS loop suture for midline incision fascial abdominal closure evaluation in patients with…
- Conditions
- Hernia Incisional, Suture Materials, Duramesh
- Trial name
- FACE (NCT07683546)
- Testing
- DURAMESH, (Ethicon) PDS II 1-0 double loop
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
HERNIA, VENTRAL
ProLOVE - Prospective Randomized Study of Midline Incisional Hernia Treatment
This purpose of this study is to compare the recovery after an operation of an incisional hernia within the limits of the rectus muscles of the abdominal wall.
- Trial name
- ProLOVE (NCT00472537)
- Testing
- Retromuscular Mesh repair of midline incisional hernia, Laparoscopic repair of midline incisional hernia
- Where
- 7 sites in Sweden
- Volunteers
- 157 people
- Sponsor
- Skane University Hospital