Clinical trials: Incisions, Surgical
Wound Dehiscence, Incision
Pediatric Post-operative Abdominal Wound Dehiscence in Association With Midline vs Other Incisions: A Prospective Cohort Study
This study is designed to see different abdominal incisions complication among neonates, infants and children and to find risk factors for developing wound dehiscence
- Trial name
- NCT05963477
- Testing
- laparatomy
- Where
- Afghanistan
- Volunteers
- 270 people
- Sponsor
- French Medical Institute for Mothers and Children
Surgical Site Infection, Post-Op Infection
Analysis of Risk Factors for Surgical Site Infections in Patients With Acute Abdomen at Hospital of State University of Haiti
The purpose of this study is to identify the risk factors associated with surgical site infection.
- Trial name
- NCT06480344
- Where
- Haiti
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Haiti
Surgical Site Infection, Antibiotics Prophylaxis
Cefuroxime vs Ceftriaxone for SSI Prevention in Neurosurgery
BACKGROUND: Surgical site infection (SSI) is potentially catastrophic in neurosurgical procedures, causing poor in-hospital outcomes in more than half of those affected and significantly increased length of hospital stay.
- Trial name
- NCT05398081
- Testing
- Cefuroxime (Zinnat®), Ceftriaxone (Rocephin®)
- Where
- Nigeria
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Dr. Promise Tamunoipiriala Jaja
Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical
Effect of Continuous Versus Interrupted Suturing on Wound Dehiscence and Infection After Abdominal Surgery
The goal of this clinical trial is to learn whether the type of suturing technique used to close the abdomen after exploratory laparotomy affects the rate of wound complications.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical, Dehiscence of Laparotomy Wound, Suture, Interrupted
- Trial name
- NCT07241507
- Testing
- Continuous suturing, Interrupted suturing
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Allama Iqbal Teaching Hospital
Cholecystectasia, Wound Heal
Infrared LED Lighting Application and Wound Healing
Laparoscopic cholecystectomy is a commonly used procedural procedure for removal of the gallbladder. Following this healing, wound healing, scar formation and scar tissue formation are critical factors in the healing process.
- Conditions
- Cholecystectasia, Wound Heal, Scar
- Trial name
- NCT06533072
- Testing
- The group receiving infrared LED therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ardahan University
Open Fracture, Post-Op Wound Infection
Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens
To demonstrate noninferiority of three different empiric antimicrobial regimens compared to the traditional antimicrobial regimen for the management of grade III open fractures as well as evaluate outcomes among these groups.
- Trial name
- NCT03560232
- Testing
- Ceftriaxone, Ampicillin/sulbactam, Piperacillin/tazobactam
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Mercy Health Ohio
Pain, Postoperative, Wound; Abdomen
Surgical Versus Anaesthetic Placement of Rectus Sheath Catheters
This is a single centred randomized controlled trial comparing surgeon versus anaesthetist inserted rectus sheath catheters for management of analgesia post major abdominal surgery.
- Conditions
- Pain, Postoperative, Wound; Abdomen, Incision
- Trial name
- SPARC (NCT03137732)
- Testing
- Rectus Sheath Catheter
- Volunteers
- 50 people
- Sponsor
- Countess of Chester NHS Foundation Trust
Anesthesia
Trans-incisional Quadratus Lumborum Block Versus Caudal Analgesia in Pediatric Open Renal Surgeries.
There is scare literature about the usage of QLB in pediatric population, particularly the trans-incisional approach. Hence, the purpose of this study is to compare the postoperative analgesic efficacy of ultrasound-guided caudal…
- Trial name
- NCT04790318
- Testing
- Trans-incisional Quadratus lumborum block, Caudal block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Operation Wound; Infection, Endometritis
Use of Antiseptic Solution for Vaginal Wash Before Cesarean Section
To evaluate the rate of infections after cesarean sections in patients with premature rupture of membranes after vaginal wash either with an antiseptic solution (clorhexidine solution) vs. saline solution (placebo).
- Trial name
- NCT03442218
- Testing
- Clorhexidine, Saline solution
- Where
- Panama
- Volunteers
- 203 people
- Sponsor
- Saint Thomas Hospital, Panama
Surgical Site Infection, Closed Suction Drains
Bacterial Colonization of Suction Drains Following Spine Surgery
Closed suction drains are commonly used following surgery, if the wound is expected to discharge significant amounts of fluid. To this date, no evidence base exists as to the exact post operative time period or discharge volume…
- Trial name
- NCT01803490
- Where
- Israel
- Volunteers
- 224 people
- Sponsor
- Western Galilee Hospital-Nahariya
Coronary Artery Disease, Valvular Heart Disease
Efficacy of Sternum Guard in Post Cardiac Surgery Patient
This is a single-center, single-blind, randomized parallel superiority trial comparing two groups; Sternum GuardTM as the treatment arm and Bone Wax as the active control group.
- Conditions
- Coronary Artery Disease, Valvular Heart Disease, Congenital Heart Disease in Adolescence, Post Operative Wound Infection
- Trial name
- NCT05229276
- Testing
- Sternum Guard, Bone Wax
- Where
- Indonesia
- Volunteers
- 414 people
- Sponsor
- Universitas Indonesia
Pilonidal Sinus, Wound Healing
ENVELOP: Wound Care Following Pilonidal Sinus Surgery
This is a single-blinded, multicentre, prospective randomised controlled trial (RCT) comparing post-operative and patient-reported outcomes for patients undergoing application of negative-pressure wound therapy (NPWT) after sinus…
- Trial name
- ENVELOP (NCT06647290)
- Testing
- Negative Pressure Wound Therapy, Standard wound care
- Where
- 10 sites in Ireland
- Volunteers
- 200 people
- Sponsor
- Royal College of Surgeons, Ireland
Hearing Loss, Conductive
Comparative Study of Two Surgical Techniques for Soft Tissue Healing and Implant Stability of Cochlear BI300 Implants.
The study compares two different operative techniques for placement of the Cochlear Bi300 implant to be used for bone anchored hearing aid.
- Trial name
- NCT01699620
- Testing
- BAHA implant insertion
- Where
- Denmark
- Volunteers
- 49 people
- Sponsor
- Aarhus University Hospital
Surgical Site Infection
Prevention of Surgical Site Infections: Effectiveness of Nasal Povidone-Iodine and Nasal Mupirocin
We hypothesize the application of mupirocin or povidone-iodine to the nares is equally effective in short term Staphylococcus aureus(SA)suppression.
- Trial name
- NCT01313182
- Testing
- mupirocin calcium ointment, 2%, 3M Skin and Nasal Antiseptic
- Where
- United States
- Volunteers
- 1,874 people
- Sponsor
- Solventum US LLC
Surgical Site Infections
Antibiotic Prophylaxis in Prosthetic Breast Reconstructions
The added benefit of prolonged antibiotic prophylactic treatment in patients undergoing breast reconstruction who have drains placed for several days after surgery is controversial.
- Trial name
- NCT02012517
- Testing
- Prolonged antibiotic treatment, Short antibiotic course (standard of care)
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Sheba Medical Center
Wound Healing, Scarring
The Effects of Topical Calcium Glycerophosphate on Surgical Wound Healing and Residual Scarring
The purpose of this study is to determine whether topical application of calcium glycerophosphate will result in superior wound appearance and scar minimization.
- Trial name
- TOPCGP-2008 (NCT01264588)
- Testing
- Topical calcium glycerophosphate lotion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- AkPharma Inc.
Cataract (Post-operative Cataract Surgery Follow-up), Refraction Error
Can Tailored Surgical Incisions Reduce Refractive Error and Dependence on Glasses After Cataract Surgery?
Astigmatism is a common cause of continued dependence on glasses after cataract surgery and may lead to patient dissatisfaction with surgical outcomes.
- Trial name
- AST-2 (NCT07623317)
- Testing
- Adapted clear corneal incisions
- Volunteers
- 100 people
- Sponsor
- Linkoeping University
Wound
Povidone-Iodine Versus Chlorhexidine in Surgical Wound Care
This comparison examines the effectiveness of povidone-iodine and chlorhexidine in managing iatrogenic wounds in surgical patients.
- Trial name
- NCT06667089
- Testing
- Povidone-Iodine, Chlorhexidine
- Where
- Spain
- Volunteers
- 107 people
- Sponsor
- University of Jaén
Breast Cancer, Sentinel Lymph Node Biopsy (SLNB)
Finding Sentinel Lymph Nodes During Mastectomy Using Indocyanine Green (INIGMA Study)
This pilot study evaluates the diagnostic value of indocyanine green (ICG) fluorescence for sentinel lymph node biopsy (SLNB) performed through the mastectomy incision in breast cancer patients.
- Conditions
- Breast Cancer, Sentinel Lymph Node Biopsy (SLNB), Sentinel Lymph Node Detection, Sentinel Lymph Node
- Trial name
- INIGMA (NCT07362485)
- Testing
- Indocyanine green (ICG)-fluorescence guided sentinel lymph node biopsy
- Where
- 2 sites in Netherlands
- Volunteers
- 90 people
- Sponsor
- Isabelle Henskens
Subjects Undergoing Cataract Surgery and Insertion of IOL
Clinical Evaluation of TrueVision System: LRI and Capsulorhexis Templates
To evaluate the ability of the TRUEVISION 3D VISUALIZATION AND GUIDANCE SYSTEM FOR MICROSURGERY to provide the ophthalmic surgeon appropriate alignment, orientation and sizing information during cataract or refractive lens…
- Trial name
- NCT01123343
- Testing
- TrueVision 3D Visualization and Guidance System for MicroSurgery
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- TrueVision Systems, Inc
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