Clinical trials: Incomplete Spinal Cord Injury (SCI)
Spinal Cord Injury
Subarachnoid Administrations of Adults Autologous Mesenchymal Stromal Cells in SCI
The study goes on 24 months, with recruiting, treatment and follow period for all patients. The first day for each patient will be the first cellular administration. 3 doses will be administrated every 3 months from first dose.
- Trial name
- NCT02165904
- Testing
- Adult Autologous Mesenchymal Bone Marrow Cell
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Puerta de Hierro University Hospital
Incomplete Spinal Cord Injury
Mental Practice Impact on Gait and Cortical Organization in Spinal Cord Injury (SCI)
Spinal cord injury (SCI) is a disabling condition that impairs fundamental abilities, such as ambulation, respiration, and toileting. Compromised ambulation is a common, devastating impairment following SCI.
- Trial name
- NCT01302522
- Testing
- Mental practice
- Sponsor
- University of Cincinnati
Spinal Cord Injury (SCI), Gait
Implant for Walking After Incomplete SCI
This is a device study that will evaluate the effect of an implanted stimulator on improving walking in people with incomplete spinal cord injury.
- Trial name
- NCT06965127
- Testing
- NNP-LE
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Louis Stokes VA Medical Center
Spinal Cord Injury
Effect of Blood Flow-restricted Exercise Frequency on Strength Recovery Following Incomplete SCI
The goal of this clinical trial is to determine the effect of treatment frequency on the physical recovery of adults with incomplete spinal cord injury.
- Trial name
- NCT07678437
- Testing
- Blood flow-restricted exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Quality Living, Inc.
Spinal Cord Injuries (Complete and Incomplete), Spinal Cord Injuries (SCI)
Feasibility of Transcutaneous Spinal Stimulation in Rehabilitation
Transcutaneous spinal stimulation (TSS) is a non-invasive neuromodulation approach that delivers electrical stimulation to spinal nerve roots through electrodes placed over the spinal cord.
- Conditions
- Spinal Cord Injuries (Complete and Incomplete), Spinal Cord Injuries (SCI), Spinal Cord Injuries and Disorders (SCI/D)
- Trial name
- NCT07898150
- Testing
- Transcutaneous Spinal Stimulation, Inpatient SCI Physiotherapy, Inpatient SCI Occupational Therapy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Janelle Unger
Incomplete Spinal Cord Injury (SCI), SCI - Spinal Cord Injury
FES-assisted Gait Training for Incomplete Spinal Cord Injury
Spinal cord injuries (SCI) impair neural communication, leading to difficulties in walking due to muscle weakness, altered reflexes, and impaired muscle activation below the injury.
- Trial name
- FES-SCI (NCT07645144)
- Testing
- FES-assisted gait training
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Stichting Reade
Spinal Cord Injuries
Lokomat® vs RoboGait® Under Different Guidance Force Settings in Motor-Incomplete SCI
This study compares two robotic-assisted gait training systems, Lokomat® and RoboGait®, used under different guidance force (GF) settings, in people with motor-incomplete spinal cord injury (iSCI).
- Trial name
- NCT07137780
- Testing
- Lokomat® V6 (GF < 90%), Lokomat® V6 (GF ≥ 90%), RoboGait®
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Ankara City Hospital Bilkent
Spinal Cord Injury
Efficacy and Safety of Growth Hormone Treatment in Spinal Cord Injury
Objectives: To evaluate the efficacy and safety of one year treatment based on daily doses of exogenous growth hormone (GH) in patients with traumatic spinal cord injury.
- Trial name
- GHSCI (NCT01329757)
- Testing
- GH
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- Hospital Nacional de Parapléjicos de Toledo
Spinal Cord Injuries, Incomplete
Protocol for Rapid Onset of Mobilization in Patients With Traumatic Spinal Cord Injury III (PROMPT-SCI III) Trial
This longitudinal cohort study will investigate the clinical benefits of early acute exercise therapy after mild spinal cord injury (SCI).
- Trial name
- PROMPT-SCI III (NCT07798310)
- Testing
- Cycling
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Spinal Cord Injuries
High Intensity Exercise in Incomplete SCI
The goal of this study is to identify the comparative efficacy of high-intensity walking training in individuals with chronic, motor incomplete spinal cord injury as compared to lower-intensity walking exercise.
- Trial name
- NCT03714997
- Testing
- Walking training
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Indiana University
Spinal Cord Injury
Improving Hand and Arm Function After Spinal Cord Injury (SCI)
The long-term goal of this project is to develop rehabilitation strategies that facilitate optimal restoration of skilled hand use in individuals with spinal cord injury (SCI).
- Trial name
- NCT01143597
- Testing
- Arm and hand training
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Miami
Spinal Cord Injuries
Functional Electrical Stimulation During Cycling in People With Spinal Cord Injury
Neuroscience research that has identified potential for recovery (neuroplasticity) following incomplete SCI has changed clinical practice away from compensation strategies towards optimizing recovery.
- Trial name
- iCycle (NCT03834324)
- Testing
- FES
- Volunteers
- 11 people
- Sponsor
- University of Southampton
Spinal Cord Injuries (SCI)
VR-Integrated C-Mill® Combined With Conventional Therapy in Motor-Incomplete SCI
This study investigates the effects of C-Mill® treadmill training, which integrates virtual reality and gamified tasks, combined with conventional physiotherapy, on walking ability, mobility, functional independence, and…
- Trial name
- NCT07141784
- Testing
- C-Mill® Treadmill Training Combined with Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people
- Sponsor
- Ankara City Hospital Bilkent
Spinal Cord Injury
Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain With Stimulation
The purpose of this study is to investigate whether combining a noninvasive method of brain stimulation, called Transcranial Direct Current Stimulation (tDCS), enhances the effect of training of the affected upper limbs in…
- Trial name
- NCT01539109
- Testing
- Rehabilitation, Noninvasive brain stimulation: tDCS
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Spinal Cord Injury
Precision Versus Endurance Training to Improve Walking After Chronic Incomplete SCI
The objective of the study was to determine the efficacy of two forms of physical therapy training, one emphasizing precise, visually guided walking over obstacles and on targets (Precision Training), the other emphasizing mass…
- Trial name
- NCT01765153
- Testing
- Endurance, Precision
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Alberta
Spinal Cord Injuries
Randomized Controlled Trial on Robotic Exoskeleton in Spinal Cord Injury: Clinical Outcomes and Cortical Plasticity
The recent introduction of robotics for locomotor training in paraplegic patients, and in particular the use of anthropomorphic exoskeletons, has opened new frontiers in rehabilitation.
- Trial name
- NCT03443700
- Testing
- EKSO-GT, Standard neurorehabilitation locomotor training
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Usl di Bologna
Spinal Cord Injuries, Muscle Pareses
A Novel Combined Neuromodulation Therapy to Enhance Balance and Neuroplasticity
Many people with partial damages in their spinal cord (iSCI) have physical impairments such as muscle paralysis in legs which make standing balance difficult.
- Conditions
- Spinal Cord Injuries, Muscle Pareses, Fall
- Trial name
- NCT05940636
- Testing
- Activity-based rehabilitation+electrical stimulation
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University Health Network, Toronto
Stroke, Incomplete Spinal Cord Injury (SCI)
ZEPU-2000 Limb Rehabilitation Trainer Study (ZEPU2000RCT)
The goal of this clinical trial is to learn whether the ZEPU-2000A, ZEPU-2000D and ZEPU-2000E robotic rehabilitation trainers help people with weakness or movement problems in their arms and legs.
- Conditions
- Stroke, Incomplete Spinal Cord Injury (SCI), Traumatic Brain Injury, Upper Extremity Motor Dysfunction
- Trial name
- NCT07749612
- Testing
- ZEPU-2000A, ZEPU-2000D, ZEPU-2000E
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University
Incomplete Spinal Cord Injury
The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients
The purpose of this study is to further establish safety and efficacy of the BQ EMF treatment of chronic SCI subjects who demonstrate stability in The Graded and Redefined Assessment of Strength, Sensibility and Prehension…
- Trial name
- NCT04050696
- Testing
- BQ 1.2
- Where
- 3 sites in United States, Israel
- Volunteers
- 8 people
- Sponsor
- BrainQ Technologies Ltd.
Incomplete Spinal Cord Injury
Effects of Transcutaneous Spinal Direct Current Stimulation in Incomplete Spinal Cord Injury
The purpose of the study is to investigate the effects of a novel therapeutic approach with transcutaneous spinal direct current stimulation (tsDCS) to promote functional recovery and spasticity in chronic spinal cord injury…
- Trial name
- NCT03249454
- Testing
- Anodal tsDCS, Cathodal tsDCS
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston