Clinical trials: Incontinence, open to volunteers
Stress Urinary Incontinence in Women
Treated Umbilical Vein Allograft (UVT) Versus Autologous Fascial Pubovaginal Sling in the Treatment of Female Stress Urinary Incontinence
The goal of this clinical trial is to evaluate whether a treated umbilical vein allograft is effective in treating stress urinary incontinence in females.
- Trial name
- NCT06678984
- Testing
- with treated umbilical vein allograft, with autologous fascial pubovaginal sling
- Where
- 8 sites in France
- Volunteers
- 96 people
- Sponsor
- TBF Genie Tissulaire
Postoperative Restriction, Midurethral Sling
Outcomes of Limited Postoperative Restrictions Following Sling Placement: A Randomized Controlled Trial
The purpose of this research study is to better understand optimal restrictions for patients postoperatively following a mesh urethral sling placement for patients with stress urinary incontinence.
- Conditions
- Postoperative Restriction, Midurethral Sling, Mesh, Stress Urinary Incontinence
- Trial name
- NCT06840093
- Testing
- Limited Restrictions, Standard Restrictions
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Iowa
Urinary Incontinence (UI), Laser Therapy
Laser Therapy and Pelvic Floor Muscle Training for Stress Urinary Incontinence
The aim of this study was to investigate the effects of Pelvic Floor Muscle Training (PFMT) in addition to high-intensity laser therapy (HILT) on pelvic floor dysfunction, sexual dysfunction, and quality of life in women with…
- Conditions
- Urinary Incontinence (UI), Laser Therapy, Stress Urinary Incontinence (SUI), Pelvic Floor Muscle Exercise
- Trial name
- NCT07319247
- Testing
- PFME and Laser Therapy, Plasebo Laser, PFME
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Necmettin Erbakan University
Urinary Incontinence, Prostatectomy
Evaluation of Non-Invasive Pelvic Floor Neuromuscular Stimulation for Urinary Incontinence After Prostatectomy
Urinary incontinence is a common complication following prostatectomy and affects a substantial proportion of patients. Despite advances in surgical technique, many patients experience persistent symptoms that negatively impact…
- Trial name
- NCT07534696
- Testing
- Non-invasive pelvic floor neuromuscular stimulation
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of California, Los Angeles
Overactive Bladder (OAB), Urgency Urinary Incontinence
Long-Term Effectiveness and Safety of Sacral Neuromodulation With InterStim for Lower Urinary Tract Dysfunction
This observational study will evaluate the long-term effectiveness, safety, and patient satisfaction associated with sacral neuromodulation using the InterStim™ system in adults treated for lower urinary tract dysfunction at…
- Conditions
- Overactive Bladder (OAB), Urgency Urinary Incontinence, Non-obstructive Urinary Retention, Non-obstructive Acontractile Detrusor
- Trial name
- NCT07856238
- Testing
- InterStim™ Sacral Neuromodulation System II - X
- Where
- Colombia
- Volunteers
- 1,700 people
- Sponsor
- Fundación Santa Fe de Bogota
Urinary Incontinence
Effects of a Multimodal and Multidimensional Intervention on Urinary Incontinence in Young Nulliparous Female Athletes.
A prevalence of urinary incontinence ranging from 5.7% to 80% has been observed in young nulliparous athletes during their activity. The usual recommendations for managing adult women do not seem to be transferable.
- Trial name
- PELVICATHLE (NCT07644273)
- Testing
- Combined pelvic health education and lumbar-pelvic-abdominal stability strengthening programme., Usual activities
- Where
- France
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Urinary Incontinence, Urinary Incontinence (UI)
Trial of NASHA Dx Urethral Bulking System
Prospective, randomized, single-blind study to evaluate the safety and efficacy of NASHA Dx investigational device compared to controlled device Bulkamid in adult women with mild, moderate and intrinsic sphincter deficiency (ISD).
- Conditions
- Urinary Incontinence, Urinary Incontinence (UI), Urinary Incontinence , Stress, Urinary Incontinence Due to Urethral Sphincter Incompetence
- Trial name
- NASHA-DX (NCT07850804)
- Testing
- NASHA Dx, Bulkamid
- Where
- 5 sites in United States
- Volunteers
- 314 people
- Sponsor
- Palette Life Sciences, Inc.
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy
Tractography-Guided Nerve-Sparing in Prostate Cancer
Radical prostatectomy (RP) is an effective treatment leading to a high rate of oncological control. However, despite advances in robot-assisted RP, the genito-urinary function, especially erectile function and urinary continence…
- Conditions
- Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy, Urinary Incontinence Following Surgical Procedure
- Trial name
- PRO-TRACT (NCT07847385)
- Testing
- Prostate Tractography for Nerve-Sparing
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Massimo Valerio
Urinary Incontinence (UI)
Comparison of Home Versus Clinic Kegel Rehabilitation in Women With Urinary Incontinence in the Tabuk Region
Urinary incontinence is a common condition among women that significantly affects physical health, emotional well-being, social participation, and overall quality of life.
- Trial name
- Incontinence (NCT07795931)
- Testing
- Home -Based Kegel Trainer Exercises (Kegel Trainer Application) will be used by the participants at home for training the pelvic floor muscles over 9 levels., Clinic-Based Rehabilitation Program will consist of physiotherapist supervised pelvic floor strengthening exercises for the participant , 2 times per week for 3 months
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- University of Tabuk
Incontinence
DEVELOPMENT AND VALIDATION OF THE URINARY INCONTINENCE KINESIOPHOBIA SEVERITY SCALE
This study aims to develop and validate a novel Turkish-language self-report instrument, the Kinesiophobia Severity Scale in Urinary Incontinence (KSS-UI), to assess movement avoidance and fear of movement associated with…
- Trial name
- NCT07842575
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Urinary Incontinence
Physiotherapy Management in Women With Urinary Incontinence
Main objective: The primary aim of the study is to assess whether the author's exercise programme has an effect on reducing urinary incontinence and pelvic floor dysfunction after childbirth, considering vacuum extractor, forceps…
- Trial name
- NCT06581601
- Testing
- physiotherapy, exercises
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Spina Bifida, Neurogenic Bowel
Bowel Continence Across the Lifespan in People With Spina Bifida
The goal of this observational study is to learn how different enema programs affect bowel control in children and adults with spina bifida.
- Conditions
- Spina Bifida, Neurogenic Bowel, Bowel Incontinence
- Trial name
- BCALS (NCT07390318)
- Testing
- Retrograde Enema, Antegrade Enema
- Where
- 24 sites in United States
- Volunteers
- 943 people
- Sponsor
- David Chu
Urinary Incontinence
Effects of Paula Exercises and Tibial Nerve Stimulation in Stress Urinary Incontinence
The aim of this study is to compare the combined effects of Paula method \& tibial nerve stimulation on incontinence, pelvic floor muscles strength, sexual function and quality of life in stress urinary incontinence
- Trial name
- NCT07576205
- Testing
- Paula Exercises, Tibial Nerve Stimulation
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Postpartum
Comparative Effects of Hypopressive and Transverses Abdominis Focused Core Training in Postpartum
The study aims to compare the effectiveness of these two core training approaches in improving urinary incontinence, pelvic floor function, and quality of life in postpartum women.
- Trial name
- NCT07576283
- Testing
- hypopressive training, transverses abdominis focused core training
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pelvic Organ Prolapse, Urinary Incontinence
Improving Uroflowmetry Interpretability: Evaluating the Impact of Patient Reminder Systems
The purpose of this study is to evaluate the impact of pre-procedure patient reminder systems on patient satisfaction, preparedness, and anxiety among patients undergoing urodynamics studies.
- Trial name
- NCT07692789
- Testing
- Patient reminder system
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Ohio State University
Stress Urinary Incontinence
Effectiveness of an 8-week Independent Cadence Retraining Program on Stress Urinary Incontinence in Parous Runners.
The purpose of this research is to assess the impact of an eight-week home cadence training program on stress urinary incontinence symptoms in parous women.
- Trial name
- NCT07829692
- Testing
- Cadence Increase, Cadence Maintenance
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Urinary Incontinence, Platelet Rich Plasma
Strategy for Managing Urinary Incontinence With PRP
Urinary incontinence is a public health issue; in France, approximately 3 million women are affected. Current treatment options-particularly surgical procedures involving the use of prosthetic materials-are being called into…
- Trial name
- PRPIU (NCT07832487)
- Testing
- Plasma rich platelet injection, Blood test, cytobacteriological examination of urine
- Where
- France
- Volunteers
- 41 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Supra-sacral Spinal Cord Injury, Spinal Cord Injury
CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury
The goal of this feasibility study is to learn whether Cannabidiol (CBD) can improve urinary incontinence and other symptoms in people with recent spinal cord injury (SCI).
- Conditions
- Supra-sacral Spinal Cord Injury, Spinal Cord Injury, Urinary Incontinence
- Trial name
- NCT06840899
- Testing
- CBD
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Urinary Incontinence (UI)
HIFEM for Incontinence After Menopause High-Intensity Focused Electromagnetic (HIFEM)
It is not difficult to imagine that leaking urine affects life in many contexts. Unfortunately, it is everyday life for far too many people in our society.
- Trial name
- HIM2025 (NCT07260604)
- Testing
- Pelvic floor training as described in point a above, with the addition of HIFEM., Pelvic Floor exercises
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI)
Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery
Suzetrigine is a selective NaV1.8 inhibitor that provides peripheral analgesia without opioid-related CNS effects. This single-center stepped-wedge randomized clinical trial evaluates whether a suzetrigine-based postoperative…
- Conditions
- Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI), Postoperative Pain
- Trial name
- NCT07600697
- Testing
- Suzetrigine, Opioid Analgesics (Tramadol or Oxycodone), Scheduled Acetaminophen and Ibuprofen
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles