Clinical trials: Indigestion
Functional Dyspepsia
Effects of Green Tea Extracts on Gastric Mucosal Protection
The investigators conduct a randomized, double-blind, placebo-controlled pilot study to investigate the effects of a combined extract of green tea seed (saponins) and green tea leaves (epigallocatechin-3-gallate) on gastric…
- Trial name
- NCT04742985
- Testing
- Green tea combined extracts group
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Functional Dyspepsia, Constipation-predominant Irritable Bowel Syndrome
Efficacy of Linaclotide in Patients With Overlapping Functional Gastrointestinal Disorders
This study aims to assess the efficacy and safety of linaclotide in patients with overlapping symptoms of both functional dyspepsia (FD) and constipation-predominant irritable bowel syndrome (IBS-C).
- Trial name
- NCT05134584
- Testing
- Linaclotide, Lactulose, Omeprazol
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Functional Dyspepsia, BIA
Bio-electrical Impedance Analysis in Patients With Functional Dyspepsia
The primary objective of this study is to compare the BIA parameters, including Phase Angle, Fat Free Mass and Fat Mass, between women with functional dyspepsia and healthy women.
- Conditions
- Functional Dyspepsia, BIA, Fat Free Mass, Fat Mass
- Trial name
- NCT07196735
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Dyspepsia
Efficacy of Motilitone on Gastric Accommodation in Healthy Adult Patients: Evaluation Using MRI Method
Functional dyspepsia (FD) is a disorder characterized by chronic or recurrent upper abdominal pain or discomfort in the absence of a specific structural cause.
- Trial name
- NCT02091635
- Testing
- Motilitone
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Functional Dyspepsia, Gastritis
The Prevalence and the Pathophysiological Role of Non-Helicobacter Pylori Helicobacter Spp. in Well-defined Gastric Diseases and (Pre-) Malignancies
The goal of this clinical trial is to discover the prevalence of NHPH bacteria (Non-Helicobacter pylori Helicobacter species) in patients with one of the following conditions: 1.
- Conditions
- Functional Dyspepsia, Gastritis, Gastritis Chronic, Gastric Cancer (GC)
- Trial name
- HELIS (NCT07770126)
- Where
- 3 sites in Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Dyspepsia
The Effects of Z-338 in Subjects With and Without Functional Dyspepsia
To assess in subjects with and without functional dyspepsia the effects of Z-338 on: 1. Type and severity of symptoms a standardized nutrient challenge 2.
- Trial name
- NCT00298194
- Testing
- Z-338
- Where
- Australia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zeria Pharmaceutical
Therapeutic Mechanism of Antidepressants for Refractory FD
MRI Study of Antidepressants in the Treatment of Refractory Functional Dyspepsia
In this study, diffusion tensor imaging（DTI）technique was used to evaluate the brain microstructures and connective white matter microstructures in patients with refractory FD, resting fMRI was used to evaluate the functional…
- Trial name
- NCT03973567
- Testing
- selective serotonin reuptake inhibitor (SSRI) or serotonin noradrenaline reuptake inhibitor (SNRI) antidepressants, conventional therapy
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Constipation, Dyspepsia
Study of Yili "Changqing" Pro-ABB Yoghurt in the Improvement of Human Gastrointestinal Tract System
The purpose of this study is to determine whether Yili "Chang Qing" Pro-ABB yoghurt is effective in improving mild constipation and the intestinal micro-ecology environment \& alimentation.
- Conditions
- Constipation, Dyspepsia, Flatulence, Abdominal Pain
- Trial name
- NCT01682798
- Testing
- Yili "Chang Qing" Pro-ABB yoghurt (Formula 1), Yili "Chang Qing" Pro-ABB yoghurt (Formula 2)
- Where
- 2 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Inner Mongolia Yili Industrial Group Co., Ltd
Dyspepsia
Abdominothoracic Muscular Tone in Functional Dyspepsia
Background. Patients with functional dyspepsia report symptoms after eating without detectable cause. A recent proof-of-concept study demonstrated that in healthy subjects, the activity of the abdominal walls influences…
- Trial name
- NCT05417204
- Testing
- Abdominothoracic biofeedback
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Barrett Esophagus, Gastroesophageal Reflux
Demographics and Findings of Upper Endoscopy Patients
The purpose of this study is to evaluate the demographics, patients symptoms, and findings during endoscopy. Patients presenting for an endoscopy procedure to the KCVA GI endoscopy suite, will be asked to fill out questionnaires…
- Trial name
- NCT00576992
- Where
- United States
- Volunteers
- 1,177 people, healthy volunteers welcome
- Sponsor
- Midwest Biomedical Research
Motility Disorder, Gastroparesis
Body Surface Gastric Mapping to Evaluate Patients With Upper Gastrointestinal Symptoms and Controls
This is an analytical validation observational cohort study is designed to provide evidence of: safety and reliability of Body Surface Gastric Mapping using the Gastric Alimetry System (GAS), normal reference values, and…
- Conditions
- Motility Disorder, Gastroparesis, Functional Dyspepsia, Cyclical Vomiting
- Trial name
- NCT05812339
- Testing
- Gastric Alimetry System
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Dyspepsia
Tricyclic Antidepressants (TCAs) on Gastric Emptying
The purpose of this study is to determine the effects of two tricyclic antidepressant agents (TCAs), amitriptyline and desipramine, on gastric emptying and gastric accommodation using a newly developed scintigraphic test that…
- Trial name
- NCT00220844
- Testing
- Desipramine, Amitriptyline
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Temple University
GI Motility Disorder
Effect of CRH on Duodenal Markers and Gastric Sensorimotor Function
In the present study, during Part 1, after a baseline gastroduodenoscopy, the investigators will perform a gastroduodenoscopy twice, to take duodenal biopsies before and 2 hours after administration of CRH/placebo.
- Trial name
- NCT05071781
- Testing
- Corticotropin-release hormone
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Allergy, Fatigue
NAET® Testing Devices in Detection of Hypersensitivity to Cane Sugar
Background: Studies have noted a correlation between food sensitivities and health disorders. Various commonly seen health problems may be caused by cane sugar since it is lavishly and frequently used by people worldwide.
- Conditions
- Allergy, Fatigue, Hypoglycemia, Hyperglycemia
- Trial name
- NCT00292578
- Testing
- NAET Testing Modalities
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nambudripad's Allergy Research Foundation
Healthy Subjects, COVID-19 Pneumonia
Jing Si Herbal Tea for Long-Coronavirus Disease(COVID) Gut-brain Interaction
Dyspepsia refers to chronic or recurrent upper gastrointestinal symptoms. According to the Rome IV criteria, functional dyspepsia (FD) symptoms included meal related fullness, early satiation, epigastric pain or burning which are…
- Conditions
- Healthy Subjects, COVID-19 Pneumonia, Irritable Bowel Syndrome, Functional Gastrointestinal Disorders
- Trial name
- NCT05668104
- Testing
- Jing Si Herbal Tea Liquid Packet
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Dyspepsia
Proton Pump Inhibitors Effects on Dyspepsia During Ramadan Fasting
evaluate the interest of proton pump inhibitors in subjects with or with GI symptoms who intend to observe fasting in Ramadan. The investigators will compare the effectiveness of proton pump inhibitors to prevent or reduce the…
- Trial name
- NCT05287633
- Testing
- Esomeprazole
- Where
- Tunisia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Food Sensitivities, Headache
NAET Screening for Food Allergy, Sensitivity and Intolerances Using IgE-Specific Antigen Test and NST- NAET®
Food allergy reactions cause various health disorders in sensitive people. These reactions may be IgE-mediated,cell-mediated, energy disturbance-mediated, or a combination of the three.
- Conditions
- Food Sensitivities, Headache, Backache, Indigestion
- Trial name
- NCT00275795
- Testing
- NAET Procedures
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nambudripad's Allergy Research Foundation
Helicobacter Pylori Infection, Dyspepsia
Effect of H. Pylori Eradication on The Improvement of Gastrointestinal Symptoms
This study aims to evaluate the effect of Helicobacter pylori eradication on gastrointestinal symptoms in adult patients. H. pylori infection is a common cause of dyspepsia and other upper gastrointestinal complaints.
- Conditions
- Helicobacter Pylori Infection, Dyspepsia, Gastrointestinal Symptoms
- Trial name
- HPE-GI (NCT07272681)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amany Usama Ahmed Arafa
Irritable Bowel Syndrome, Dyspepsia
Visible Abdominal Distension
Background. Abdominal distention is produced by an abnormal somatic postural tone. The authors developed an original biofeedback technique.
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Bloating
- Trial name
- NCT06369753
- Testing
- Biofeedback
- Where
- 7 sites in United States, Canada and 5 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Irritable Bowel Syndrome, Functional Dyspepsia
The Multi-disciplinary Treatment of Functional Gut Disorders Study
Randomised controlled trial comparing standard outpatient clinic treatment with multi-disciplinary clinic treatment for functional gastrointestinal disorders.
- Conditions
- Irritable Bowel Syndrome, Functional Dyspepsia, Constipation - Functional, Faecal Incontinence
- Trial name
- MANTRA (NCT03078634)
- Testing
- Multi-disciplinary clinic model, Standard outpatient care
- Where
- Australia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- St Vincent's Hospital Melbourne