Clinical trials: Indigestion
Dyspepsia
Heterogeneous Distribution of Health Literacy and Emotional State on Patients With Functional Dyspepsia.
Patients with indigestion were often found in gastroenterology clinic, those who about 20 % was caused by organic, while the rest of patients are showed abnormal inspection, and these are so called functional dyspepsia.
- Trial name
- NCT02737683
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Dysbiosis
PPI and Microbiome in Healthy Volunteers and Functional Dyspepsia
Prospective interventional study of the effect of PPI on the duodenal microbiome in healthy volunteers and functional dyspepsia patients
- Trial name
- NCT03545243
- Testing
- Pantoprazole 40mg, PPI withdrawal
- Where
- Belgium
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Functional Dyspepsia
Assessment of GI Function to a Large Test Meal by Non-invasive Imaging
Dyspeptic symptoms such as abdominal pain, bloating and nausea after a meal are common; however the cause of these problems in many patients is often unclear despite medical investigation.
- Trial name
- NCT03007433
- Testing
- 400ml of Liquid Nutrient Drink
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Healthy Subjects, COVID-19 Pneumonia
Jing Si Herbal Tea for Long-Coronavirus Disease(COVID) Gut-brain Interaction
Dyspepsia refers to chronic or recurrent upper gastrointestinal symptoms. According to the Rome IV criteria, functional dyspepsia (FD) symptoms included meal related fullness, early satiation, epigastric pain or burning which are…
- Conditions
- Healthy Subjects, COVID-19 Pneumonia, Irritable Bowel Syndrome, Functional Gastrointestinal Disorders
- Trial name
- NCT05668104
- Testing
- Jing Si Herbal Tea Liquid Packet
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Functional Dyspepsia
Study of Endogenous Inhibitory Modulation During Gastric and Somatic Stimulation
Visceral hypersensitivity as evidence of central sensory sensitization is evident in many patients with functional disorders such as functional dyspepsia (FD) and irritable bowel syndrome (IBS).
- Trial name
- NCT00693407
- Testing
- gastric capsaicin with heterotopic stimulation/ distraction
- Where
- 2 sites in Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Irritable Bowel Syndrome, Functional Dyspepsia
The Multi-disciplinary Treatment of Functional Gut Disorders Study
Randomised controlled trial comparing standard outpatient clinic treatment with multi-disciplinary clinic treatment for functional gastrointestinal disorders.
- Conditions
- Irritable Bowel Syndrome, Functional Dyspepsia, Constipation - Functional, Faecal Incontinence
- Trial name
- MANTRA (NCT03078634)
- Testing
- Multi-disciplinary clinic model, Standard outpatient care
- Where
- Australia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- St Vincent's Hospital Melbourne
Irritable Bowel Syndrome, Dyspepsia
Treatment of Functional Abdominal Distension by Non-instrumental Biofeedback
Background. Abdominal distention is produced by an abnormal somatic postural tone. The authors developed an original biofeedback technique based on electromyography-guided control of abdominothoracic muscular activity.
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Bloating
- Trial name
- NCT06150638
- Testing
- Biofeedback
- Where
- Spain
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Functional Dyspepsia
Functional Dyspepsia Hypnosis
The purpose of this study is to evaluate the efficacy of a hypnotherapy treatment program for functional dyspepsia that can be self-administered using on-line audio recordings. This is a non-randomized study.
- Trial name
- NCT03884270
- Testing
- Hypnotherapy
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Sarah Kinsinger
Functional Dyspepsia
Duodenal Microbiota in Functional Dyspepsia
The goal of this observational study is to assess the type of duodenal microbiota and duodenal microbiome in in FD patients compared to control group.
- Trial name
- NCT06326918
- Testing
- Duodenal mucosal brushing, Duodenal mucosal biopsy
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Chulalongkorn Memorial Hospital
Gastroparesis, Dyspepsia
Longitudinal Evaluation of Gastric Emptying and Accommodation in Children With Dyspepsia
The purpose of this research is to further study the relationship between gastroparesis (GP) (a condition in which the stomach cannot empty itself of food in a normal fashion) and functional dyspepsia (FD) (frequent symptoms of…
- Trial name
- NCT05055336
- Testing
- Gastric emptying breath test, Stomach ultrasound
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Dyspepsia
Defining Central Circuits of Pain
The purpose of the study is to use functional Magnetic Resonance Imaging (MRI) to help us understand what parts of the subject's brain are involved when he experiences visceral pain, or pain in the gut.
- Trial name
- NCT00112333
- Testing
- fMRI
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Signs and Symptoms, Digestive, Dyspepsia
Evaluation of the Effect of a Probiotic Supplement Upon Gastrointestinal Function
The purpose of this pilot study is to evaluate whether a probiotic supplement improves gastrointestinal (GI) function.
- Trial name
- NCT02928484
- Testing
- Probiotic mix CBP-004019/C
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biopolis S.L.
Functional Dyspepsia
Mechanisms of Electroacupuncture for Functional Dyspepsia Based on "Enterotypes" and Metabolomics
The goal of this clinical trial is to explore the clinical efficacy and possible mechanisms of electroacupuncture treatment for functional dyspepsia (FD).
- Trial name
- NCT05920395
- Testing
- Electro-acupuncture
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Wuhan Central Hospital
Functional Dyspepsia
Physiological Response and Visual Attention to Visual Food Images in Healthy Subjects and in Functional Dyspepsia Patients
In functional dyspepsia (FD), abnormal cognitive and emotional changes such increased sensitization, anxiety, and depression scores have been reported in addition to the peripheral changes in gastrointestinal tract functions.
- Trial name
- NCT02727556
- Testing
- visual images
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Dyspepsia
The Effects of Z-338 in Subjects With and Without Functional Dyspepsia
To assess in subjects with and without functional dyspepsia the effects of Z-338 on: 1. Type and severity of symptoms a standardized nutrient challenge 2.
- Trial name
- NCT00298194
- Testing
- Z-338
- Where
- Australia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zeria Pharmaceutical
Dyspepsia, Healthy
Effect of Secretin in Functional Dyspepsia and Healthy Subjects
Insights into the pathophysiology of functional dyspepsia, with recent demonstration of inflammation with eosinophilia and mastocytosis in the duodenum (3, 6, 7), providing a possible lead toward reduced secretion of a potential…
- Trial name
- NCT03617861
- Testing
- Human Secretin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis
Biomagnetic Characterization of Gastric Dysrhythmias III
There is a tremendous clinical need for a noninvasive technique that can assess gastric electrical activity and would be repeatable without any exposure to radiation.
- Conditions
- Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis, Total or Partial Gastrectomy
- Trial name
- NCT03176927
- Testing
- magnetogastrogram
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Functional Dyspepsia, BIA
Bio-electrical Impedance Analysis in Patients With Functional Dyspepsia
The primary objective of this study is to compare the BIA parameters, including Phase Angle, Fat Free Mass and Fat Mass, between women with functional dyspepsia and healthy women.
- Conditions
- Functional Dyspepsia, BIA, Fat Free Mass, Fat Mass
- Trial name
- NCT07196735
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Functional Dyspepsia, Irritable Bowel Syndrome
The Efficacy and Safety of "BST104" (Lonicera Flos Extract) in Mild to Moderate Functional Dyspepsia Subjects
This study was conducted to prove the efficacy of BST-104 in patients with mild to moderate FD.
- Trial name
- NCT04008901
- Testing
- BST-104 (Lonicera Flos Extract)
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
IBS-D and Functional Dyspepsia
Trenev Trio/Healthy Trinity for Symptoms of Diarrhea-predominant Irritable Bowel Syndrome (IBS) and Functional Dyspepsia
Primary Objective: To confirm the efficacy of the probiotic product Healthy Trinity (retail label)/Trenev Trio (professional label) in the improvement of symptoms in adult patients with diarrhea-predominant irritable bowel…
- Trial name
- NCT01268618
- Testing
- Probiotic
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sprim Advanced Life Sciences