Clinical trials: Individuality, open to volunteers
Condition: Healthy
Resting-state Connectivity and Individual Differences in Affective Placebo Responsiveness
Expectation effects on affective states are central to mechanisms relevant for mood disorders and their treatment. This study will test whether inter-individual differences in resting-state functional connectivity (rsFC) within…
- Trial name
- NCT07479966
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stefanie Brassen
Stuttering, Developmental, Dyslexia
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an…
- Conditions
- Stuttering, Developmental, Dyslexia, Healthy Participants
- Trial name
- NCT07459803
- Testing
- Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Colour Perception, Color Perception
Visual Perception, Binocular Rivalry, and Fatigue-Related Individual Differences in Colour and Illumination Judgement
This observational study aims to characterise individual differences in colour perception and binocular rivalry. Participants will complete computer-based visual perception tasks, including a colour perception task and a…
- Conditions
- Colour Perception, Color Perception, Binocular Rivalry
- Trial name
- NCT07671144
- Testing
- Computer-Based Visual Perception Tasks
- Where
- 2 sites in Hong Kong
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Chronic Low Back Pain, Spinal Cord Injury
SERENITY Study of Chronic Pain Interference in Adults
SERENITY is a remote observational study designed to characterize inter-individual differences in chronic pain among adults with chronic low back pain and adults with spinal cord injury-related neuropathic pain.
- Conditions
- Chronic Low Back Pain, Spinal Cord Injury, Neuropathic Pain, Chronic Pain
- Trial name
- SERENITY (NCT07820475)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Minnesota
Type 2 Diabetes Mellitus in Obese, Type 2 Diabetes
LCMD for Type 2 Diabetes Remission: Evaluation of Effectiveness and Exploration of Individual Differences
Type 2 diabetes (T2DM) has become a major public health problem. Achieving remission (HbA1c<6.5% without glucose-lowering medications) has recently become a new treatment goal.
- Trial name
- LCMD (NCT06442150)
- Testing
- Low-Calorie Medicine Diet, Low-Calorie Diet
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Shanghai Municipal Hospital of Traditional Chinese Medicine
Circadian Rhythm, Time Perception
Circadian Timing and Time Perception in Healthy Adults
This study examines how a person's natural daily rhythm ("chronotype") affects the way time is experienced and judged. Healthy Danish-speaking adults (23-45 years) who are clearly morning-type or evening-type will complete two…
- Trial name
- ChronoTime (NCT07292597)
- Testing
- Session timing relative to chronotype
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Aging, Alzheimer Disease
Exercise to Improve Brain Health in Older African Americans
The goal of this clinical trial is to test the effects of different types of exercise on brain health and Alzheimer's risk in older African Americans.
- Conditions
- Aging, Alzheimer Disease, Healthy Aging, Cognitive Change
- Trial name
- NCT05597124
- Testing
- Cardio-Dance Fitness, Strength, Flexibility & Balance
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Healthy Volunteers
Manipulating Social Percepts During fMRI
This study will investigate the use of real-time fMRI to change how participants perceive social information.
- Trial name
- NCT07528378
- Testing
- Real-time fMRI: Brain-state- triggered trials, Real-time fMRI: Covert neurofeedback
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Emotions, Anhedonia
Geolocation Positional System (GPS) Experience
The purpose of this study is to use smartphone technology to capture individual location emotional and cognitive data, to examine how real-world behaviors thoughts, emotions, and brain activity are related to one another.
- Conditions
- Emotions, Anhedonia, Depression
- Trial name
- NCT05991713
- Testing
- Modifying Exploration
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Healthy
Individual Differences in Placebo Analgesic Effects
This study examines the effects of placebo suggestions tailored to match or mismatch individual participants' motivational styles-an issue of person-situation 'fit' with important effects in public health settings, but which has…
- Trial name
- NCT04669093
- Testing
- Control cream
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Eye Movements, Attention
An Investigation of Attentional and Inhibitory Processes During Active Visual Search in Humans
The goal of this study is to investigate the finding that there are large individual differences in how participants move their eyes during active visual search.
- Conditions
- Eye Movements, Attention, Executive Function
- Trial name
- NCT06587113
- Testing
- Contour Search Task, Stop signal Task, Useful field of View
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Knee Osteoarthritis (OA), Chronic Pain
Individual Differences in Gait and Osteoarthritis Pain
The goal of this observational study is to look at inter-individual differences in knee osteoarthritis (OA) walking pain and performance.
- Conditions
- Knee Osteoarthritis (OA), Chronic Pain, Chronic Knee Pain
- Trial name
- INDIGO (NCT07308873)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder
More and Less Social Comprehension
The goal of this early Phase 1 clinical trial is to assess if the social content of a story impacts autistic children's listening comprehension of stories.
- Trial name
- MLSC (NCT06116552)
- Testing
- More Social Stories, Less Social Stories
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Kansas Medical Center
Healthy Control, Depression
Concurrent TMS-fMRI
The goal of this clinical trial is to examine the neural mechanisms underlying transcranial magnetic stimulation (TMS) using concurrent functional magnetic resonance imaging (fMRI) in both healthy controls (HCs) and patients with…
- Trial name
- NCT06633913
- Testing
- spTMS-TBS-spTMS
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Jing Jiang
Developmental Language Disorder
Syntactic Intervention for Cantonese-speaking Children With DLD
The goal of this clinical trial is to compare the efficacy of explicit vs. implicit intervention on subject relative clause production in Cantonese-speaking children with Developmental Language Disorder (DLD).
- Trial name
- NCT06954194
- Testing
- Explicit intervention (Shape Coding+syntactic priming), Implicit intervention (syntactic priming only)
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- The Hong Kong Polytechnic University
Behavior, Depressive Disorder
Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time
This study investigates the computational mechanisms associated with psychiatric disease dimensions. The study will characterize the relationship between computational parameter estimates of task performance and psychiatric…
- Conditions
- Behavior, Depressive Disorder, Anxiety Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- CABxtime (NCT06705179)
- Testing
- Behavioral task performance
- Where
- 2 sites in United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- California Institute of Technology
Healthy Adult Participants
Alcohol Sensitivity Among Older Adults Who Consume Alcohol
This is a proof-of-concept study exploring individual differences in sensitivity to alcohol among older healthy current drinkers aged 65 to 80.
- Trial name
- NCT07636447
- Testing
- Alcohol (Oral)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Florida
Math Learning Disability, Child Development
Interventions in Mathematics and Cognitive Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities
- Trial name
- NCT05201534
- Testing
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Healthy
Individual Differences in Cognitive Control Predict Real-time fMRI Neurofeedback Performance
The goal of this study is to investgate whether individual differences of cognitive control capacity could predict neurofeedback performance and the behavioral effects resulting from successful anterior insula regulation via…
- Trial name
- NCT07211269
- Testing
- Real-time fMRI neurofeedback training
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China